N
Nithin Karakala
Professor
faculty
Internal Med, College of Medicine
13 h-index
44 pubs
667 cited
Research Areas
Links
Biography and Research Information
OverviewAI-generated summary
Nithin Karakala, Professor of Internal Medicine at the University of Arkansas for Medical Sciences, focuses his research on biomarkers in renal disease. His clinical interests include continuous renal replacement therapy, early prognostic markers for acute kidney injury (AKI), and volume management in AKI.
Dr. Karakala's work has been published in peer-reviewed journals, with recent publications investigating urinary NGAL as a marker for AKI in cirrhosis, the role of SOD1 as a prognostic biomarker in AKI following cardiothoracic surgery, and the prognostic significance of IGFBP-1 in AKI. He has also published on terlipressin for hepatorenal syndrome and vascular access for continuous renal replacement therapy.
With an h-index of 13 and 39 total publications, Dr. Karakala collaborates with researchers at UAMS, including Luis A. Juncos, Joseph H. Holthoff, Manisha Singh, and Neriman Gökden. He maintains an active lab website to share his research.
Research Overview
Dr. Karakala is an Assistant Professor of Medicine in the Division of Nephrology, Department of Internal Medicine. He received his medical degree from Deccan College of Medical Sciences in India. He completed his internal medicine residency at Greater Baltimore Medical Center in Maryland and his nephrology fellowship training at Medical University of South Carolina. He served as the Chief Nephrology Fellow at MUSC as well. Dr. Karakala was on the faculty at MUSC for two years before coming to UAMS. Dr. Karakala is board certified in internal medicine and nephrology. His clinical interests are continuous renal replacement therapy, early prognostic markers of acute kidney injury, and volume management in acute kidney injury. His research interests include biomarkers in renal disease.
Metrics
- h-index: 13
- Publications: 44
- Citations: 667
Selected Publications
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Perfusion Under Pressure: Reversing Anuric AKI with Targeted Intra-Abdominal Pressure (IAP) Reduction (2025)
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Protective Phosphorus Ranges for Major Adverse Cardiovascular Events in CKD: Insights from Spline-Based Survival Models (2025)
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Calculated Preemptive Strike: Solving Overcorrection of Hyponatremia with Math and Medicine (2025)
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Hypophosphatemia as a Marker for Immune Effector Cell-Associated Neurotoxicity Syndrome in Chimeric Antigen Receptor T Cell Recipients (2025)
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SGLT2 Inhibitors as a Therapeutic Option for Both Acute and Chronic Refractory Hypomagnesemia in Diabetic and Nondiabetic Patients: A Multicenter Case Series (2025)
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The role of IGFBP-1 in the clinical prognosis and pathophysiology of acute kidney injury (2025)
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Gastrointestinal Mucosal Cell Injury Caused by Sevelamer Crystals: Case Series and Literature Review (2025)
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Urine Chemistry: A Valuable Link Binding Kidney Physiology to Patient Care (2024)
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Stepwise Teamwork Approach Saves Patients Extensive Work-Up (2024)
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Urinary Complement C3 and Vitamin D-Binding Protein Predict Adverse Outcomes in Patients with Acute Kidney Injury after Cardiac Surgery (2024)
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I Am in a Crystal Bind! A Case that Gave Us Ulcers (2023)
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The Drug that Keeps Giving: Hypomagnesemia Fixed by SGLT2 Inhibitor (2023)
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SOD1 is a novel prognostic biomarker of acute kidney injury following cardiothoracic surgery (2023)
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High-Cutoff Hemodialysis Therapy for Patients with Light Chain Cast Nephropathy and AKI Requiring Dialysis: CON (2023)
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Responsiveness to Vasoconstrictor Therapy in Hepatorenal Syndrome Type 1 (2023)
Grants & Funding
- Clinical Scientist Award UAMS Principal Investigator
- No FP attached Potrero Medical - Pass Through: Biomedical Research Foundation - Arkansas Principal Investigator
- Clinical Scientist Award UAMS Principal Investigator
- Targeting Abdominal Perfusion Pressure in Septic Shock (The MAP APP Study) IRB 228252 Potrero Medical - Pass Through: Biomedical Research Foundation - Arkansas Principal Investigator
Collaboration Network
Top Collaborators
Luis A. Juncos
Central Arkansas Veterans Healthcare System
8 shared publications
In database
- Urinary NGAL as a Diagnostic and Prognostic Marker for Acute Kidney Injury in Cirrhosis: A Prospective Study
- Terlipressin and the Treatment of Hepatorenal Syndrome: How the CONFIRM Trial Moves the Story Forward
- Vascular access, membranes and circuit for CRRT
- Point-of-Care Ultrasound in Acute Care Nephrology
- SOD1 is a novel prognostic biomarker of acute kidney injury following cardiothoracic surgery
Showing 5 of 8 shared publications
Joseph H. Holthoff
University of Arkansas for Medical Sciences
6 shared publications
In database
- SOD1 is a novel prognostic biomarker of acute kidney injury following cardiothoracic surgery
- The Drug that Keeps Giving: Hypomagnesemia Fixed by SGLT2 Inhibitor
- The role of IGFBP-1 in the clinical prognosis and pathophysiology of acute kidney injury
- Urine Chemistry: A Valuable Link Binding Kidney Physiology to Patient Care
- SGLT2 Inhibitors as a Therapeutic Option for Both Acute and Chronic Refractory Hypomagnesemia in Diabetic and Nondiabetic Patients: A Multicenter Case Series
Showing 5 of 6 shared publications
Andrew S. Allegretti
Massachusetts General Hospital (US)
3 shared publications
- Urinary NGAL as a Diagnostic and Prognostic Marker for Acute Kidney Injury in Cirrhosis: A Prospective Study
- Terlipressin and the Treatment of Hepatorenal Syndrome: How the CONFIRM Trial Moves the Story Forward
- Responsiveness to Vasoconstrictor Therapy in Hepatorenal Syndrome Type 1
Kevin R. Regner
Medical College of Wisconsin (US)
3 shared publications
- Urinary NGAL as a Diagnostic and Prognostic Marker for Acute Kidney Injury in Cirrhosis: A Prospective Study
- Terlipressin and the Treatment of Hepatorenal Syndrome: How the CONFIRM Trial Moves the Story Forward
- Responsiveness to Vasoconstrictor Therapy in Hepatorenal Syndrome Type 1
Justin M. Belcher
VA Connecticut Healthcare System (US)
3 shared publications
- Urinary NGAL as a Diagnostic and Prognostic Marker for Acute Kidney Injury in Cirrhosis: A Prospective Study
- Terlipressin and the Treatment of Hepatorenal Syndrome: How the CONFIRM Trial Moves the Story Forward
- Responsiveness to Vasoconstrictor Therapy in Hepatorenal Syndrome Type 1
Juan Carlos Q. Velez
Ochsner Health System (US)
3 shared publications
- Urinary NGAL as a Diagnostic and Prognostic Marker for Acute Kidney Injury in Cirrhosis: A Prospective Study
- Terlipressin and the Treatment of Hepatorenal Syndrome: How the CONFIRM Trial Moves the Story Forward
- Responsiveness to Vasoconstrictor Therapy in Hepatorenal Syndrome Type 1
Ahmed Abdallah
University of Arkansas for Medical Sciences (US)
3 shared publications
- The Drug that Keeps Giving: Hypomagnesemia Fixed by SGLT2 Inhibitor
- I Am in a Crystal Bind! A Case that Gave Us Ulcers
- Stepwise Teamwork Approach Saves Patients Extensive Work-Up
Ahmed Elkalashy
University of Arkansas for Medical Sciences
3 shared publications
In database
- The Drug that Keeps Giving: Hypomagnesemia Fixed by SGLT2 Inhibitor
- I Am in a Crystal Bind! A Case that Gave Us Ulcers
- Gastrointestinal Mucosal Cell Injury Caused by Sevelamer Crystals: Case Series and Literature Review
Kiran Chandrashekar
Central Arkansas Veterans Healthcare System (US)
2 shared publications
- Vascular access, membranes and circuit for CRRT
- Point-of-Care Ultrasound in Acute Care Nephrology
Xavier Vela Parada
Massachusetts General Hospital (US)
2 shared publications
- Urinary NGAL as a Diagnostic and Prognostic Marker for Acute Kidney Injury in Cirrhosis: A Prospective Study
- Terlipressin and the Treatment of Hepatorenal Syndrome: How the CONFIRM Trial Moves the Story Forward
Douglas A. Simonetto
WinnMed (US)
2 shared publications
- Urinary NGAL as a Diagnostic and Prognostic Marker for Acute Kidney Injury in Cirrhosis: A Prospective Study
- Terlipressin and the Treatment of Hepatorenal Syndrome: How the CONFIRM Trial Moves the Story Forward
Hani M. Wadei
Mayo Clinic in Florida (US)
2 shared publications
- Urinary NGAL as a Diagnostic and Prognostic Marker for Acute Kidney Injury in Cirrhosis: A Prospective Study
- Terlipressin and the Treatment of Hepatorenal Syndrome: How the CONFIRM Trial Moves the Story Forward
Mitra K. Nadim
University of Southern California (US)
2 shared publications
- Urinary NGAL as a Diagnostic and Prognostic Marker for Acute Kidney Injury in Cirrhosis: A Prospective Study
- Terlipressin and the Treatment of Hepatorenal Syndrome: How the CONFIRM Trial Moves the Story Forward
Guadalupe García–Tsao
Massachusetts General Hospital (US)
2 shared publications
- Urinary NGAL as a Diagnostic and Prognostic Marker for Acute Kidney Injury in Cirrhosis: A Prospective Study
- Terlipressin and the Treatment of Hepatorenal Syndrome: How the CONFIRM Trial Moves the Story Forward
Samir M. Parikh
Beth Israel Deaconess Medical Center (US)
2 shared publications
- Urinary NGAL as a Diagnostic and Prognostic Marker for Acute Kidney Injury in Cirrhosis: A Prospective Study
- Terlipressin and the Treatment of Hepatorenal Syndrome: How the CONFIRM Trial Moves the Story Forward
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