Lisa M. Pence

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NCTR

Also affiliated: United States Food and Drug Administration (2010–2022); Center for Drug Evaluation and Research (2020); Eskenazi Health (2014); University of Oklahoma Health Sciences Center (2001)

16 h-index 36 pubs 654 cited

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OverviewAI-generated summary

Lisa M. Pence's research focuses on the application of metabolomics and proteomics to understand disease mechanisms and identify biomarkers. She has investigated acylcarnitine profiles in acetaminophen toxicity in both pediatric human patients and mouse models, examining relationships with metabolism and hepatocyte regeneration. Pence has also explored early metabolomics changes in the heart and plasma during chronic doxorubicin treatment in mice. Her work includes the discovery of novel proteomic biomarkers for predicting kidney recovery in dialysis-dependent acute kidney injury patients. Additionally, she has studied methylation potential in relation to diet, genotype, and metabolite levels, as well as the stability of the human plasma proteome to pre-analytical variability using an aptamer-based approach. Pence's scholarship metrics include an h-index of 16, with 36 total publications and 737 total citations.

Metrics

h-index: 16
Publications: 36
Citations: 654

Selected Publications

Effects of Serum and Compound Preparation Methods on Delayed Repolarization Evaluation With Human iPSC-CMs (2022)

Toxicological Sciences 6 citations DOI OpenAlex
Serum metabolite profiles predict outcomes in critically ill patients receiving renal replacement therapy (2021)

Journal of Chromatography B 17 citations DOI OpenAlex
Discovery of Novel Proteomic Biomarkers for the Prediction of Kidney Recovery from Dialysis-Dependent AKI Patients (2021)

Kidney360 34 citations DOI OpenAlex
Distinct lipid signatures are identified in the plasma of rats with chronic inflammation induced by estradiol benzoate and sex hormones (2020)

Metabolomics 8 citations DOI OpenAlex
Hepatic Transcript Profiles of Cytochrome P450 Genes Predict Sex Differences in Drug Metabolism (2020)

Drug Metabolism and Disposition 22 citations DOI OpenAlex
Stability of the Human Plasma Proteome to Pre-analytical Variability as Assessed by an Aptamer-Based Approach (2019)

Journal of Proteome Research 31 citations DOI OpenAlex
An Integrated Analysis of Metabolites, Peptides, and Inflammation Biomarkers for Assessment of Preanalytical Variability of Human Plasma (2019)

Journal of Proteome Research 27 citations DOI OpenAlex
Testicular function in cultured postnatal mouse testis fragments is similar to that of animals during the first wave of spermatogenesis (2019)

Birth Defects Research 23 citations DOI OpenAlex
An Aptamer‐Based Approach to Assess the Human Plasma Proteome for Pre‐Analytical Variability (2018)

The FASEB Journal DOI OpenAlex
Targeted metabolomic profiling indicates structure-based perturbations in serum phospholipids in children with acetaminophen overdose (2016)

Toxicology Reports 13 citations DOI OpenAlex
Early metabolomics changes in heart and plasma during chronic doxorubicin treatment in B6C3F1 mice (2016)

Journal of Applied Toxicology 40 citations DOI OpenAlex
Comparison of Bile Acids and Acetaminophen Protein Adducts in Children and Adolescents with Acetaminophen Toxicity (2015)

PLoS ONE 27 citations DOI OpenAlex
Genetic associations with micronutrient levels identified in immune and gastrointestinal networks (2014)

Genes & Nutrition 16 citations DOI OpenAlex
Targeted Liquid Chromatography–Mass Spectrometry Analysis of Serum Acylcarnitines in Acetaminophen Toxicity in Children (2014)

Biomarkers in Medicine 69 citations DOI OpenAlex
Comprehensive analysis of alterations in lipid and bile acid metabolism by carbon tetrachloride using integrated transcriptomics and metabolomics (2014)

Metabolomics 6 citations DOI OpenAlex