Oscar Zuniga

Researcher

University of Arkansas for Medical Sciences

unknown

1 h-index 7 pubs 5 cited

Research Areas

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OverviewAI-generated summary

Oscar Zuniga's research focuses on understanding and overcoming therapeutic resistance in various cancers, with a particular emphasis on pancreatic and rectal cancers. His work investigates molecular mechanisms that contribute to radioresistance and explores strategies to enhance the efficacy of radiation therapy. Recent publications explore the role of signaling pathways, such as the RAS-RAF-miR-296-3p axis, in increasing Rad18 expression to augment radioresistance. Additionally, Zuniga's research examines methods to improve radiosensitization, including targeting specific genes like SETD2 and employing dietary interventions such as methionine restriction. His studies also address the targeting of homologous repair mechanisms to combat genotoxic therapy resistance in pancreatic cancer. Zuniga collaborates with researchers at the University of Arkansas for Medical Sciences, including Henrique Rodrigues, Lokesh Akana, Nükhet Aykin‐Burns, and Isabelle Racine Miousse, contributing to a collective effort in cancer research.

Metrics

h-index: 1
Publications: 7
Citations: 5

Selected Publications

Enhancing Rectal Cancer Radiosensitivity and Gut Protection through Methionine Restriction (2025) DOI
RAS-RAF-miR-296-3p signaling axis increases Rad18 expression to augment radioresistance in pancreatic and thyroid cancers (2024) DOI
Abstract A006: Targeting SETD2 in combination with radiotherapy in rectal cancer (2024) DOI
Ras-Raf-Mir-296-3p Signaling Axis Increases Rad18 Expression to Augment Radioresistance in Pancreatic and Thyroid Cancers (2023) DOI
Abstract 2839: Methionine restriction radiosensitizes KRAS mutant rectal cancer (2023) DOI
205 Targeting Homologous Repair to Overcome Genotoxic Therapy Resistance in Pancreatic Cancer (2022) DOI