Paul Bertone Source Confirmed

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

High Impact

Principal Investigator

John Brown University

faculty

55 h-index 110 pubs 17,418 cited

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Biography and Research Information

OverviewAI-generated summary

Paul Bertone, a principal investigator at John Brown University, focuses on genomics and chromatin dynamics, with applications spanning pluripotent stem cell research, phylogenetic studies, and cancer biology. His investigations extend to gene expression analysis for cancer classification and the use of CRISPR technology for genetic engineering. Recent work includes characterizing transcriptional programs acquired by glioblastomas to evade immune detection via epigenetic immunoediting and exploring the influence of hydrogel mechanical properties on pluripotent stem cells. Bertone's research also encompasses transcriptional profiling of pulmonary artery endothelial cells in pulmonary hypertension and the role of BCL-2 proteins in castration-resistant prostate cancer.

Metrics

  • h-index: 55
  • Publications: 110
  • Citations: 17,418

Selected Publications

  • Enabling CAR-T Cell Immunotherapy in Glioblastoma by Modifying Tumor Microenvironment via Oncolytic Adenovirus Encoding Bispecific T Cell Engager (2025) DOI
  • The Role of BCL-2 Proteins in the Development of Castration-resistant Prostate Cancer and Emerging Therapeutic Strategies (2021) DOI

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