Qinglei Gan
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Research Associate
Also affiliated: Iowa State University (2007–2011); University of Guelph (2008)
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Qinglei Gan's research focuses on understanding post-translational modifications (PTMs) of proteins, particularly lysine acetylation, and developing methods for their site-specific installation. Gan has investigated these modifications in various biological systems, including Escherichia coli, humans, and maize (Zea mays). Recent work has explored the characterization of lysine acetylation in specific enzymes like malate dehydrogenase and isocitrate dehydrogenase, as well as methyl-coenzyme M reductase. Gan has also explored the genetic incorporation of multiple PTMs into single proteins and developed orthogonal translation systems for site-specific PTM installation. Collaborations at the University of Arkansas at Fayetteville with Chenguang Fan, Nour Fatema, and Sara Ottinger, as well as with Carson W. Ercanbrack at the University of Arkansas for Medical Sciences, have contributed to a publication record of 39 papers, with an h-index of 18 and over 1,000 citations.
Metrics
- h-index: 18
- Publications: 37
- Citations: 1,109
Positions
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Research Associate publications 2016–2026University of Arkansas at Fayetteville Institution web page
Selected Publications
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Expanding the Genetic Code with Lysine Aminoacylation (2026)
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Additional file 1 of Genome-wide screening of antibiotic survival genes in Escherichia coli MG1655 (2026)
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Additional file 1 of Genome-wide screening of antibiotic survival genes in Escherichia coli MG1655 (2026)
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Genome-wide screening of antibiotic survival genes in Escherichia coli MG1655 (2026)
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Genome-wide screening of antibiotic survival genes in Escherichia coli MG1655 (2026)
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Genome-wide screening of antibiotic survival genes in Escherichia coli MG1655 (2026)
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Functional consequences of lysine acetylation of phosphofructokinase isozymes (2025)
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Orthogonal Translation for Site-Specific Installation of Post-translational Modifications (2024)
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Characterizing lysine acetylation of glucokinase (2023)
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“ Not‐so‐popular ” orthogonal pairs in genetic code expansion (2022)
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Studying Acetylation of Aconitase Isozymes by Genetic Code Expansion (2022)
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Genome-Wide Screening of Oxidizing Agent Resistance Genes in Escherichia coli (2021)
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Introducing noncanonical amino acids for studying and engineering bacterial microcompartments (2021)
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Methyl-Coenzyme M Reductase and Its Post-translational Modifications (2020)
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A Synthetic Reporter for Probing Mistranslation in Living Cells (2020)
Collaboration Network
Top Collaborators
- Studying the Lysine Acetylation of Malate Dehydrogenase
- Genetically Incorporating Two Distinct Post-translational Modifications into One Protein Simultaneously
- Methyl-Coenzyme M Reductase and Its Post-translational Modifications
- Orthogonal Translation for Site-Specific Installation of Post-translational Modifications
- Characterizing Lysine Acetylation of Isocitrate Dehydrogenase in Escherichia coli
Showing 5 of 30 shared publications
- Studying the Lysine Acetylation of Malate Dehydrogenase
- Genetically Incorporating Two Distinct Post-translational Modifications into One Protein Simultaneously
- Characterizing Lysine Acetylation of Isocitrate Dehydrogenase in Escherichia coli
- Recent Development of Genetic Code Expansion for Posttranslational Modification Studies
- Characterizing lysine acetylation of Escherichia coli type II citrate synthase
Showing 5 of 13 shared publications
- Studying the Lysine Acetylation of Malate Dehydrogenase
- Genetically Incorporating Two Distinct Post-translational Modifications into One Protein Simultaneously
- Genetically encoding thioacetyl‐lysine as a non‐deacetylatable analog of lysine acetylation in Escherichia coli
- Biochemical Characterization of the Lysine Acetylation of Tyrosyl‐tRNA Synthetase in Escherichia coli
- A Facile Protocol to Generate Site-Specifically Acetylated Proteins in Escherichia Coli
Showing 5 of 6 shared publications
- Characterizing Lysine Acetylation of Isocitrate Dehydrogenase in Escherichia coli
- Recent Development of Genetic Code Expansion for Posttranslational Modification Studies
- Characterizing lysine acetylation of Escherichia coli type II citrate synthase
- Genome-Wide Quantification of the Effect of Gene Overexpression on Escherichia coli Growth
- Genome-wide screening of antibiotic survival genes in Escherichia coli MG1655
- Genome-wide screening of antibiotic survival genes in Escherichia coli MG1655
- Additional file 1 of Genome-wide screening of antibiotic survival genes in Escherichia coli MG1655
- Additional file 1 of Genome-wide screening of antibiotic survival genes in Escherichia coli MG1655
- Genetically Incorporating Two Distinct Post-translational Modifications into One Protein Simultaneously
- Characterizing Lysine Acetylation of Isocitrate Dehydrogenase in Escherichia coli
- Characterizing lysine acetylation of Escherichia coli type II citrate synthase
- Characterizing Lysine Acetylation of Isocitrate Dehydrogenase in Escherichia coli
- Characterizing lysine acetylation of Escherichia coli type II citrate synthase
- Genome-Wide Quantification of the Effect of Gene Overexpression on Escherichia coli Growth
- Genome-Wide Screening of Oxidizing Agent Resistance Genes in Escherichia coli
- Genome-Wide Quantification of the Effect of Gene Overexpression on Escherichia coli Growth
- Introducing noncanonical amino acids for studying and engineering bacterial microcompartments
- The Application of Cell-Free Protein Synthesis in Genetic Code Expansion for Post-translational Modifications
- Site-Specifically Studying Lysine Acetylation of Aminoacyl-tRNA Synthetases
- A Synthetic Reporter for Probing Mistranslation in Living Cells
- Studying the Lysine Acetylation of Malate Dehydrogenase
- Genetically Incorporating Two Distinct Post-translational Modifications into One Protein Simultaneously
- Characterizing Lysine Acetylation of Isocitrate Dehydrogenase in Escherichia coli
- Site-Specifically Studying Lysine Acetylation of Aminoacyl-tRNA Synthetases
- Site-Specifically Studying Lysine Acetylation of Aminoacyl-tRNA Synthetases
- A Synthetic Reporter for Probing Mistranslation in Living Cells
- Genome-Wide Screening of Oxidizing Agent Resistance Genes in Escherichia coli
- A Synthetic Reporter for Probing Mistranslation in Living Cells
- Studying Acetylation of Aconitase Isozymes by Genetic Code Expansion
- Introducing noncanonical amino acids for studying and engineering bacterial microcompartments
- Characterizing lysine acetylation of glucokinase
- Functional consequences of lysine acetylation of phosphofructokinase isozymes
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