Chenguang Fan Data-verified

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

Federal Grant PI High Impact

Assistant Professor

Last publication 2026 Last refreshed 2026-05-22

faculty

34 h-index 78 pubs 4,126 cited

Biography and Research Information

OverviewAI-generated summary

Chenguang Fan studies the fundamental mechanisms of biological processes, with a particular focus on protein modifications and genetic code expansion. His research investigates the role of lysine acetylation in human metabolic enzymes, including aconitase isozymes and glucokinase, utilizing genetic code expansion techniques to understand these post-translational modifications. Fan also examines the function ofthreonyl-tRNA synthetase in relation to lysine acetylation. His work extends to bacterial genetics, including genome-wide screening for resistance genes in *Escherichia coli*.

Fan's research group has received significant funding from the National Institutes of Health (NIH)/National Institute of General Medical Sciences for two projects totaling over $1 million. These grants support his investigations into lysine aminoacylation of human metabolic enzymes and the role of lysine acetylation in human threonyl-tRNA synthetase. He is recognized as a high-impact researcher with 77 publications and over 4,000 citations, and has a collaboration network including researchers from the University of Arkansas at Fayetteville and the University of Arkansas for Medical Sciences.

Beyond his primary research areas, Fan's publication record includes work on cellulose-based biomaterials for biomedical applications and thermal storage in ice units, indicating a breadth of scientific interest and potential interdisciplinary collaborations.

Metrics

  • h-index: 34
  • Publications: 78
  • Citations: 4,126

Selected Publications

  • Additional file 1 of Genome-wide screening of antibiotic survival genes in Escherichia coli MG1655 (2026)
  • Additional file 1 of Genome-wide screening of antibiotic survival genes in Escherichia coli MG1655 (2026)
  • Genome-wide screening of antibiotic survival genes in Escherichia coli MG1655 (2026)
  • Genome-wide screening of antibiotic survival genes in Escherichia coli MG1655 (2026)
  • Genome-wide screening of antibiotic survival genes in Escherichia coli MG1655 (2026)
  • Crystal structures of <i>Escherichia coli</i> glucokinase and insights into phosphate binding (2025)
    1 citation DOI OpenAlex
  • Functional consequences of lysine acetylation of phosphofructokinase isozymes (2025)
    2 citations DOI OpenAlex
  • Orthogonal Translation for Site-Specific Installation of Post-translational Modifications (2024)
    40 citations DOI OpenAlex
  • Characterizing lysine acetylation of glucokinase (2023)
    5 citations DOI OpenAlex
  • Studying lysine acetylation of citric acid cycle enzymes by genetic code expansion (2023)
    3 citations DOI OpenAlex
  • “<scp>Not‐so‐popular</scp>” orthogonal pairs in genetic code expansion (2022)
    17 citations DOI OpenAlex
  • Modifications of cellulose-based biomaterials for biomedical applications (2022)
    48 citations DOI OpenAlex
  • Editorial: Engineering Nucleic Acids-Based Functional Nanomaterials, Nanodrugs, and Biosensors (2022)
    1 citation DOI OpenAlex
  • Studying Acetylation of Aconitase Isozymes by Genetic Code Expansion (2022)
    13 citations DOI OpenAlex
  • Editorial: Synthetic Nucleic Acids for Expanding Genetic Codes and Probing Living Cells (2021)
    2 citations DOI OpenAlex

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Federal Grants 2 $1,012,500 total

NIH/National Institute of General Medical Sciences Contact PI Sep 2025 - Aug 2028

Studying lysine aminoacylation of human metabolic enzymes

National Institute of General Medical Sciences $562,500 R15
NIH/National Institute of General Medical Sciences Contact PI Dec 2020 - Nov 2024

The role of lysine acetylation of human threonyl-tRNA synthetase

National Institute of General Medical Sciences $450,000 R15

Collaboration Network

29 Collaborators 11 Institutions 4 Countries

Top Collaborators

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