Roger G. Rank
professor emeritus
Also affiliated: Arkansas Children's Hospital (1995–2020); The University of Texas at San Antonio Health Science Center (1997); University of California, San Francisco (2001); Wayne State University (2010); University of Washington (1995); University of Arkansas Medical Center (2008–2014); Veterans Health Administration (1981); Audie L. Murphy Memorial VA Hospital (1996–1997); Hahnemann University Hospital (1975–1976); Central Arkansas Veterans Healthcare System (1981–1988); San Antonio State Chest Hospital (1994); Arkansas Children's Nutrition Center (2016); John L. McClellan Memorial Veterans Hospital (1979); Texas Center for Infectious Disease (1995); Arkansas Children's Research Institute (2008–2020); UConn Health (1995)
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Roger G. Rank's research has focused on the study of molecular biology techniques and applications. His work includes investigations into the mechanisms of various diseases and the development of potential treatments. Rank has also contributed to the understanding of immune responses and inflammation, as well as the pharmacological effects of compounds. His publications span several years, indicating a sustained engagement with these scientific areas.
Metrics
- h-index: 48
- Publications: 120
- Citations: 5,847
Positions
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professor emeritus publications 1979–2020University of Arkansas for Medical Sciences Institution web page
Selected Publications
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Endocervical miRNA Expression Profiles in Women Positive for Chlamydia trachomatis with Clinical Signs and/or Symptoms Are Distinct from Those in Women Positive for Chlamydia trachomatis without Signs and Symptoms (2020)
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Differential signaling pathways are initiated in macrophages during infection depending on the intracellular fate of Chlamydia spp. (2018)
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Erratum to: Formula diet alters small intestine morphology, microbial abundance and reduces VE-cadherin and IL-10 expression in neonatal porcine model (2016)
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MicroRNAs Modulate Pathogenesis Resulting from Chlamydial Infection in Mice (2016)
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Formula diet alters small intestine morphology, microbial abundance and reduces VE-cadherin and IL-10 expression in neonatal porcine model (2016)
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Chlamydial Variants Differ in Ability To Ascend the Genital Tract in the Guinea Pig Model of Chlamydial Genital Infection (2015)
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Is it time to switch to doxycycline from azithromycin for treating genital chlamydial infections in women? Modelling the impact of autoinoculation from the gastrointestinal tract to the genital tract (2015)
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Genomic variant representation in a Chlamydia population is dynamic and adaptive with dependence on in vitro and in vivo passage (2015)
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In Vivo Chlamydial Infection (2014)
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Models of Immunity (2014)
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STI-GMaS: An open-source environment for simulation of sexually-transmitted infections (2014)
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Erratum for Yeruva et al., Early MicroRNA Expression Profile as a Prognostic Biomarker for the Development of Pelvic Inflammatory Disease in a Mouse Model of Chlamydial Genital Infection (2014)
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Early MicroRNA Expression Profile as a Prognostic Biomarker for the Development of Pelvic Inflammatory Disease in a Mouse Model of Chlamydial Genital Infection (2014)
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Hidden in Plain Sight: Chlamydial Gastrointestinal Infection and Its Relevance to Persistence in Human Genital Infection (2014)
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Use of a Guinea Pig-Specific Transcriptome Array for Evaluation of Protective Immunity against Genital Chlamydial Infection following Intranasal Vaccination in Guinea Pigs (2014)
Collaboration Network
Top Collaborators
- Chlamydial infection of the gastrointestinal tract: a reservoir for persistent infection
- Strain and Virulence Diversity in the Mouse Pathogen Chlamydia muridarum
- In VivoUltrastructural Analysis of the Intimate Relationship between Polymorphonuclear Leukocytes and the Chlamydial Developmental Cycle
- Early MicroRNA Expression Profile as a Prognostic Biomarker for the Development of Pelvic Inflammatory Disease in a Mouse Model of Chlamydial Genital Infection
- Characterization of Lymphocyte Response in the Female Genital Tract during Ascending Chlamydial Genital Infection in the Guinea Pig Model
Showing 5 of 14 shared publications
- Hidden in Plain Sight: Chlamydial Gastrointestinal Infection and Its Relevance to Persistence in Human Genital Infection
- Chlamydial infection of the gastrointestinal tract: a reservoir for persistent infection
- Early MicroRNA Expression Profile as a Prognostic Biomarker for the Development of Pelvic Inflammatory Disease in a Mouse Model of Chlamydial Genital Infection
- Formula diet alters small intestine morphology, microbial abundance and reduces VE-cadherin and IL-10 expression in neonatal porcine model
- Differential Susceptibilities to Azithromycin Treatment of Chlamydial Infection in the Gastrointestinal Tract and Cervix
Showing 5 of 12 shared publications
- A New Animal Model for the Study of Chlamydia trachomatis Genital Infections: Infection of Mice with the Agent of Mouse Pneumonitis
- Target Tissues Associated with Genital Infection of Female Guinea Pigs by the Chlamydial Agent of Guinea Pig Inclusion Conjunctivitis
- Effects of Various Doses of Estradiol on Chlamydial Genital Infection in Ovariectomized Guinea Pigs
- Absence of Progesterone Effects on Chlamydial Genital Infection in Female Guinea Pigs
- Chlamydial Salpingitis in Female Guinea Pigs Receiving Oral Contraceptives
Showing 5 of 10 shared publications
- Chlamydial infection of the gastrointestinal tract: a reservoir for persistent infection
- Early MicroRNA Expression Profile as a Prognostic Biomarker for the Development of Pelvic Inflammatory Disease in a Mouse Model of Chlamydial Genital Infection
- Formula diet alters small intestine morphology, microbial abundance and reduces VE-cadherin and IL-10 expression in neonatal porcine model
- Differential Susceptibilities to Azithromycin Treatment of Chlamydial Infection in the Gastrointestinal Tract and Cervix
- Endocervical miRNA Expression Profiles in Women Positive for Chlamydia trachomatis with Clinical Signs and/or Symptoms Are Distinct from Those in Women Positive for Chlamydia trachomatis without Signs and Symptoms
Showing 5 of 8 shared publications
- Early Local Cytokine Profiles in Strains of Mice with Different Outcomes from Chlamydial Genital Tract Infection
- Critical Role for Interleukin-1β (IL-1β) duringChlamydia muridarumGenital Infection and Bacterial Replication-Independent Secretion of IL-1β in Mouse Macrophages
- Chlamydia trachomatis Induces Expression of IFN-γ-Inducible Protein 10 and IFN-β Independent of TLR2 and TLR4, but Largely Dependent on MyD88
- A Role for Interleukin-6 in Host Defense against MurineChlamydia trachomatisInfection
- Role of Proapoptotic BAX in Propagation of Chlamydia muridarum (the Mouse Pneumonitis Strain of Chlamydia trachomatis) and the Host Inflammatory Response
Showing 5 of 8 shared publications
- Resolution of chlamydial genital infection in B-cell-deficient mice and immunity to reinfection
- Resolution of chlamydial genital infection with antigen-specific T-lymphocyte lines
- Effect of gamma interferon on resolution of murine chlamydial genital infection
- Humoral immune response to chlamydial genital infection of mice with the agent of mouse pneumonitis
- Strain and Virulence Diversity in the Mouse Pathogen Chlamydia muridarum
Showing 5 of 7 shared publications
- AChlamydia trachomatis-Specific Th2 Clone Does Not Provide Protection against a Genital Infection and Displays Reduced Trafficking to the Infected Genital Mucosa
- A Role for Interleukin-6 in Host Defense against MurineChlamydia trachomatisInfection
- Characterization of Lymphocyte Response in the Female Genital Tract during Ascending Chlamydial Genital Infection in the Guinea Pig Model
- Differential Regulation of CD4 Lymphocyte Recruitment between the Upper and Lower Regions of the Genital Tract duringChlamydia trachomatisInfection
- Expression of Mucosal Homing Receptor α4β7 Is Associated with Enhanced Migration to theChlamydia-Infected Murine Genital Mucosa In Vivo
Showing 5 of 7 shared publications
- Critical Role for Interleukin-1β (IL-1β) duringChlamydia muridarumGenital Infection and Bacterial Replication-Independent Secretion of IL-1β in Mouse Macrophages
- Chlamydia trachomatis Induces Expression of IFN-γ-Inducible Protein 10 and IFN-β Independent of TLR2 and TLR4, but Largely Dependent on MyD88
- Essential Role for Neutrophils in Pathogenesis and Adaptive Immunity in Chlamydia caviae Ocular Infections
- Molecular characterization of guinea ‐ pig (Cavia porcellus) CD8α and CD8β cDNA
- Differential signaling pathways are initiated in macrophages during infection depending on the intracellular fate of Chlamydia spp.
Showing 5 of 6 shared publications
- Mouse strain-dependent variation in the course and outcome of chlamydial genital tract infection is associated with differences in host response
- Early Local Cytokine Profiles in Strains of Mice with Different Outcomes from Chlamydial Genital Tract Infection
- Critical Role for Interleukin-1β (IL-1β) duringChlamydia muridarumGenital Infection and Bacterial Replication-Independent Secretion of IL-1β in Mouse Macrophages
- Mouse Strain-Dependent Chemokine Regulation of the Genital Tract T Helper Cell Type 1 Immune Response
- Role of Proapoptotic BAX in Propagation of Chlamydia muridarum (the Mouse Pneumonitis Strain of Chlamydia trachomatis) and the Host Inflammatory Response
Showing 5 of 6 shared publications
- Prospects for a vaccine against Chlamydia genital disease I. — Microbiology and pathogenesis
- Systemic immunization with Hsp60 alters the development of chlamydial ocular disease.
- Prospects for a vaccine against Chlamydia genital disease II. — Immunity and vaccine development
- Genomic Plasticity of therrn-nqrFIntergenic Segment in theChlamydiaceae
- The chlamydial invasin-like protein gene conundrum
- Protective role of serum antibody in immunity to chlamydial genital infection
- Susceptibility to reinfection after a primary chlamydial genital infection
- Role of cell-mediated immunity in the resolution of secondary chlamydial genital infection in guinea pigs infected with the agent of guinea pig inclusion conjunctivitis
- Immunization against chlamydial genital infection in guinea pigs with UV-inactivated and viable chlamydiae administered by different routes
- Endocervical miRNA Expression Profiles in Women Positive for Chlamydia trachomatis with Clinical Signs and/or Symptoms Are Distinct from Those in Women Positive for Chlamydia trachomatis without Signs and Symptoms
- Role for CD8+ T cells in antichlamydial immunity defined by Chlamydia-specific T-lymphocyte clones
- Susceptibility to reinfection after a primary chlamydial genital infection is associated with a decrease of antigen-specific T cells in the genital tract
- Integrin-mediated epithelial-T cell interaction enhances nitric oxide production and increased intracellular inhibition of Chlamydia
- Inhibition of Intracellular Multiplication of Human Strains ofChlamydia trachomatisby Nitric Oxide
- An in vitro model for immune control of chlamydial growth in polarized epithelial cells
- A New Animal Model for the Study of Chlamydia trachomatis Genital Infections: Infection of Mice with the Agent of Mouse Pneumonitis
- Target Tissues Associated with Genital Infection of Female Guinea Pigs by the Chlamydial Agent of Guinea Pig Inclusion Conjunctivitis
- Chlamydial Salpingitis in Female Guinea Pigs Receiving Oral Contraceptives
- Cystitis Associated with Chlamydia IInfection of the Genital Tract in Male Guinea Pigs
- Response of Guinea Pigs to Intravaginal Inoculation with Guinea Pig Cytomegalovirus
- A New Animal Model for the Study of Chlamydia trachomatis Genital Infections: Infection of Mice with the Agent of Mouse Pneumonitis
- Target Tissues Associated with Genital Infection of Female Guinea Pigs by the Chlamydial Agent of Guinea Pig Inclusion Conjunctivitis
- Cystitis Associated with Chlamydia IInfection of the Genital Tract in Male Guinea Pigs
- Ultrastructural studies of chlamydial infection in guinea-pig urogenital tract
- Electron microscopic observations concerning the in vivo uptake and release of the agent of guinea-pig inclusion conjunctivitis (Chlamydia psittaci) in guinea-pig exocervix
- Early MicroRNA Expression Profile as a Prognostic Biomarker for the Development of Pelvic Inflammatory Disease in a Mouse Model of Chlamydial Genital Infection
- Impact of Azithromycin Resistance Mutations on the Virulence and Fitness of Chlamydia caviae in Guinea Pigs
- Effect of Inflammatory Response on In Vivo Competition between Two Chlamydial Variants in the Guinea Pig Model of Inclusion Conjunctivitis
- Chlamydial Variants Differ in Ability To Ascend the Genital Tract in the Guinea Pig Model of Chlamydial Genital Infection
- Erratum for Yeruva et al., Early MicroRNA Expression Profile as a Prognostic Biomarker for the Development of Pelvic Inflammatory Disease in a Mouse Model of Chlamydial Genital Infection
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