Shelley E. Crary
Professor, Pediatric Hematology-Oncology
Also affiliated: Children's Medical Center (2007–2013); Arkansas Children's Hospital (2013–2026); Berkeley College (2019); University of Arkansas Medical Center (2018–2024); Erasmus MC (2023); Clinical Research Institute (2011); Cook Children's Medical Center (2008); Southwestern Medical Center (2008–2010); Center for Cancer and Blood Disorders (2007–2013); Duke Medical Center (2011); Pediatrics and Genetics (2017); Southwestern Medical Center (2009–2010); American Society for Clinical Pathology (2019); The University of Texas Southwestern Medical Center (2005–2013); Amsterdam UMC Location Vrije Universiteit Amsterdam (2023); University of California, Berkeley (2019)
Faculty Researcher
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Dr. Shelley E. Crary is a Professor of Pediatrics in the Division of Pediatric Hematology-Oncology at the University of Arkansas for Medical Sciences (UAMS) and Arkansas Children’s Hospital (ACH). She holds leadership positions as the Medical Director of the Arkansas Center for Bleeding Disorders and Director of Hematology at ACH. Dr. Crary also serves as Co-Director of the UAMS Clinical and Translational Science Pilot Program, focusing on advancing translational research and supporting career development for junior faculty and fellows.
Her research interests include the treatment of hematologic conditions in children, with recent publications addressing gene therapy for Hemophilia B, anticoagulant therapy for venous thromboembolism, and treatment practices for kaposiform hemangioendothelioma and vascular malformations. Dr. Crary also investigates pharmacokinetic properties of sclerotherapy agents and approaches to coagulopathy in patients with vascular anomalies. Her work has contributed to understanding long-term biological effects in sickle cell disease and defining pediatric refractory immune thrombocytopenia (ITP).
Dr. Crary is actively involved in medical education and mentorship, co-directing the UAMS Master’s in Clinical and Translational Sciences Scholarship Program and participating in the American Society of Hematology (ASH) Classical Hematology Mentorship Program. She earned her undergraduate degree from Washington University in St. Louis and her medical degree from Tulane University School of Medicine, followed by residency at Vanderbilt University and a fellowship at UT Southwestern Medical Center, where she also obtained a Master of Science in Clinical Science.
Metrics
- h-index: 20
- Publications: 99
- Citations: 2,051
Selected Publications
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Bone Mineral Density, Bone Remodeling Biomarkers, and Hemostatic Correlates in Hemophilia and von Willebrand Disease (2026)
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ReInspire: A Phase 2 Study of Mutant-Selective PI3Kα Inhibitor, RLY-2608, in Adults and Children with PIK3CA-Related Overgrowth Spectrum and Malformations Driven by PIK3CA Mutation (2026)
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HTRS2025.P1.27 Prevalence Vitamin D deficiency and risk factors for poor bone health in persons with Hemophilia A and B in Arkansas – A retrospective single institution study (2025)
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Recombinant von willebrand factor for perioperative management of bleeding in pediatric patients with severe von willebrand disease: Interim results from a phase 3 multicenter study and a phase 3b continuation study (2025)
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Multimodal neuroimaging and neurocognitive assessment in adolescents with and without sickle cell disease (2025)
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End-of-study results from the ICON3 pines trial, a phase 3, randomized trial of eltrombopag vs. standard first-line treatment for newly diagnosed immune thrombocytopenia in children (2025)
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Knowledge, interest, and willingness of hematologists and oncologists to care for adults with vascular anomalies (2025)
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Eltrombopag for Newly Diagnosed Pediatric Immune Thrombocytopenia Requiring Treatment (2025)
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Parental Adverse Childhood Experiences and Health Care Use Among Children With Sickle Cell Disease (2025)
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Pediatric hematology: selected topics (2025)
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The Functional Characterization of Venous Thromboembolic Disease (FUVID) study: rationale, design, and methods of a prospective, observational, multicenter study to evaluate mechanisms of exercise intolerance and dyspnea following pediatric pulmonary embolism (2024)
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Hemostasis and thrombosis risks and management in vascular anomalies (2024)
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Efficacy Findings in a Phase 3, Randomized Trial of Eltrombopag Vs. Standard First-Line Treatment for Newly Diagnosed Immune Thrombocytopenia in Children (2024)
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Hypercoagulability Evaluation in Pediatric Kidney Transplant Recipients to Optimize Outcomes (2024)
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What is in a name: defining pediatric refractory ITP (2024)
Grants & Funding
As listed on this researcher's institutional profile.
- CUMG UAMS College of Medicine
- GR034186-Crary-HRSA Great Plains Regional Hemophilia Network-UT University of Texas via UAMS ACHRI Flow Through
- Public Health Surveillance for the Prevention of Complications of Bleeding and Clotting UAMS ACHRI Flow Through
Collaboration Network
Top Collaborators
- Pharmacokinetics of bleomycin sclerotherapy in patients with vascular malformations
- How we approach coagulopathy with vascular anomalies
- Hypercoagulability Evaluation in Pediatric Kidney Transplant Recipients to Optimize Outcomes
- Parental Adverse Childhood Experiences and Health Care Use Among Children With Sickle Cell Disease
- How we approach coagulopathy with vascular anomalies.
Showing 5 of 7 shared publications
- Treatment practices and response in kaposiform hemangioendothelioma: A multicenter cohort study
- What is in a name: defining pediatric refractory ITP
- A Phase 3 Study of Eltrombopag Vs. Standard First-Line Management for Newly Diagnosed Immune Thrombocytopenia in Children: Trial in Progress Update
- Efficacy Findings in a Phase 3, Randomized Trial of Eltrombopag Vs. Standard First-Line Treatment for Newly Diagnosed Immune Thrombocytopenia in Children
- Eltrombopag for Newly Diagnosed Pediatric Immune Thrombocytopenia Requiring Treatment
Showing 5 of 6 shared publications
- What is in a name: defining pediatric refractory ITP
- A Phase 3 Study of Eltrombopag Vs. Standard First-Line Management for Newly Diagnosed Immune Thrombocytopenia in Children: Trial in Progress Update
- Efficacy Findings in a Phase 3, Randomized Trial of Eltrombopag Vs. Standard First-Line Treatment for Newly Diagnosed Immune Thrombocytopenia in Children
- Eltrombopag for Newly Diagnosed Pediatric Immune Thrombocytopenia Requiring Treatment
- End-of-study results from the ICON3 pines trial, a phase 3, randomized trial of eltrombopag vs. standard first-line treatment for newly diagnosed immune thrombocytopenia in children
- What is in a name: defining pediatric refractory ITP
- A Phase 3 Study of Eltrombopag Vs. Standard First-Line Management for Newly Diagnosed Immune Thrombocytopenia in Children: Trial in Progress Update
- Efficacy Findings in a Phase 3, Randomized Trial of Eltrombopag Vs. Standard First-Line Treatment for Newly Diagnosed Immune Thrombocytopenia in Children
- Eltrombopag for Newly Diagnosed Pediatric Immune Thrombocytopenia Requiring Treatment
- End-of-study results from the ICON3 pines trial, a phase 3, randomized trial of eltrombopag vs. standard first-line treatment for newly diagnosed immune thrombocytopenia in children
- What is in a name: defining pediatric refractory ITP
- A Phase 3 Study of Eltrombopag Vs. Standard First-Line Management for Newly Diagnosed Immune Thrombocytopenia in Children: Trial in Progress Update
- Efficacy Findings in a Phase 3, Randomized Trial of Eltrombopag Vs. Standard First-Line Treatment for Newly Diagnosed Immune Thrombocytopenia in Children
- Eltrombopag for Newly Diagnosed Pediatric Immune Thrombocytopenia Requiring Treatment
- End-of-study results from the ICON3 pines trial, a phase 3, randomized trial of eltrombopag vs. standard first-line treatment for newly diagnosed immune thrombocytopenia in children
- What is in a name: defining pediatric refractory ITP
- A Phase 3 Study of Eltrombopag Vs. Standard First-Line Management for Newly Diagnosed Immune Thrombocytopenia in Children: Trial in Progress Update
- Efficacy Findings in a Phase 3, Randomized Trial of Eltrombopag Vs. Standard First-Line Treatment for Newly Diagnosed Immune Thrombocytopenia in Children
- Eltrombopag for Newly Diagnosed Pediatric Immune Thrombocytopenia Requiring Treatment
- End-of-study results from the ICON3 pines trial, a phase 3, randomized trial of eltrombopag vs. standard first-line treatment for newly diagnosed immune thrombocytopenia in children
- What is in a name: defining pediatric refractory ITP
- A Phase 3 Study of Eltrombopag Vs. Standard First-Line Management for Newly Diagnosed Immune Thrombocytopenia in Children: Trial in Progress Update
- Efficacy Findings in a Phase 3, Randomized Trial of Eltrombopag Vs. Standard First-Line Treatment for Newly Diagnosed Immune Thrombocytopenia in Children
- Eltrombopag for Newly Diagnosed Pediatric Immune Thrombocytopenia Requiring Treatment
- End-of-study results from the ICON3 pines trial, a phase 3, randomized trial of eltrombopag vs. standard first-line treatment for newly diagnosed immune thrombocytopenia in children
- Parental Adverse Childhood Experiences and Health Care Use Among Children With Sickle Cell Disease
- Poor School Performance As an Indicator of Severity of Sickle Cell Disease
- A case of bruising and joint hypermobility: The need to consider genetic testing for platelet disorders
- HTRS2025.P1.27 Prevalence Vitamin D deficiency and risk factors for poor bone health in persons with Hemophilia A and B in Arkansas – A retrospective single institution study
- A Phase 3 Study of Eltrombopag Vs. Standard First-Line Management for Newly Diagnosed Immune Thrombocytopenia in Children: Trial in Progress Update
- Efficacy Findings in a Phase 3, Randomized Trial of Eltrombopag Vs. Standard First-Line Treatment for Newly Diagnosed Immune Thrombocytopenia in Children
- Eltrombopag for Newly Diagnosed Pediatric Immune Thrombocytopenia Requiring Treatment
- End-of-study results from the ICON3 pines trial, a phase 3, randomized trial of eltrombopag vs. standard first-line treatment for newly diagnosed immune thrombocytopenia in children
- A Phase 3 Study of Eltrombopag Vs. Standard First-Line Management for Newly Diagnosed Immune Thrombocytopenia in Children: Trial in Progress Update
- Efficacy Findings in a Phase 3, Randomized Trial of Eltrombopag Vs. Standard First-Line Treatment for Newly Diagnosed Immune Thrombocytopenia in Children
- Eltrombopag for Newly Diagnosed Pediatric Immune Thrombocytopenia Requiring Treatment
- End-of-study results from the ICON3 pines trial, a phase 3, randomized trial of eltrombopag vs. standard first-line treatment for newly diagnosed immune thrombocytopenia in children
- A Phase 3 Study of Eltrombopag Vs. Standard First-Line Management for Newly Diagnosed Immune Thrombocytopenia in Children: Trial in Progress Update
- Efficacy Findings in a Phase 3, Randomized Trial of Eltrombopag Vs. Standard First-Line Treatment for Newly Diagnosed Immune Thrombocytopenia in Children
- Eltrombopag for Newly Diagnosed Pediatric Immune Thrombocytopenia Requiring Treatment
- End-of-study results from the ICON3 pines trial, a phase 3, randomized trial of eltrombopag vs. standard first-line treatment for newly diagnosed immune thrombocytopenia in children
- A Phase 3 Study of Eltrombopag Vs. Standard First-Line Management for Newly Diagnosed Immune Thrombocytopenia in Children: Trial in Progress Update
- Efficacy Findings in a Phase 3, Randomized Trial of Eltrombopag Vs. Standard First-Line Treatment for Newly Diagnosed Immune Thrombocytopenia in Children
- Eltrombopag for Newly Diagnosed Pediatric Immune Thrombocytopenia Requiring Treatment
- End-of-study results from the ICON3 pines trial, a phase 3, randomized trial of eltrombopag vs. standard first-line treatment for newly diagnosed immune thrombocytopenia in children
- A Phase 3 Study of Eltrombopag Vs. Standard First-Line Management for Newly Diagnosed Immune Thrombocytopenia in Children: Trial in Progress Update
- Efficacy Findings in a Phase 3, Randomized Trial of Eltrombopag Vs. Standard First-Line Treatment for Newly Diagnosed Immune Thrombocytopenia in Children
- Eltrombopag for Newly Diagnosed Pediatric Immune Thrombocytopenia Requiring Treatment
- End-of-study results from the ICON3 pines trial, a phase 3, randomized trial of eltrombopag vs. standard first-line treatment for newly diagnosed immune thrombocytopenia in children
- A Phase 3 Study of Eltrombopag Vs. Standard First-Line Management for Newly Diagnosed Immune Thrombocytopenia in Children: Trial in Progress Update
- Efficacy Findings in a Phase 3, Randomized Trial of Eltrombopag Vs. Standard First-Line Treatment for Newly Diagnosed Immune Thrombocytopenia in Children
- Eltrombopag for Newly Diagnosed Pediatric Immune Thrombocytopenia Requiring Treatment
- End-of-study results from the ICON3 pines trial, a phase 3, randomized trial of eltrombopag vs. standard first-line treatment for newly diagnosed immune thrombocytopenia in children
- A Phase 3 Study of Eltrombopag Vs. Standard First-Line Management for Newly Diagnosed Immune Thrombocytopenia in Children: Trial in Progress Update
- Efficacy Findings in a Phase 3, Randomized Trial of Eltrombopag Vs. Standard First-Line Treatment for Newly Diagnosed Immune Thrombocytopenia in Children
- Eltrombopag for Newly Diagnosed Pediatric Immune Thrombocytopenia Requiring Treatment
- End-of-study results from the ICON3 pines trial, a phase 3, randomized trial of eltrombopag vs. standard first-line treatment for newly diagnosed immune thrombocytopenia in children
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