Shelley E. Crary
Professor, Pediatric Hematology-Oncology
Also affiliated: University of North Carolina at Chapel Hill (2023); Children's Medical Center (2007–2013); Arkansas Children's Hospital (2013–2026); University Medical Center Groningen (2023); Duke University (2011); Utrecht University (2023); University of Michigan (2023); University of Arkansas Medical Center (2018–2026); Erasmus MC (2023); University Medical Center Utrecht (2023); Cook Children's Medical Center (2008); Center for Cancer and Blood Disorders (2010–2011); Duke Medical Center (2011); American Society of Pediatric Hemotology Oncology (2019); Amsterdam University Medical Centers (2023); The University of Texas Southwestern Medical Center (2005–2013); University of Amsterdam (2023); Erasmus University Rotterdam (2023); University of California, Berkeley (2019)
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Dr. Shelley E. Crary is a Professor of Pediatrics in the Division of Pediatric Hematology-Oncology at the University of Arkansas for Medical Sciences (UAMS) and Arkansas Children’s Hospital (ACH). She holds leadership positions as the Medical Director of the Arkansas Center for Bleeding Disorders and Director of Hematology at ACH. Dr. Crary also serves as Co-Director of the UAMS Clinical and Translational Science Pilot Program, focusing on advancing translational research and supporting career development for junior faculty and fellows.
Her research interests include the treatment of hematologic conditions in children, with recent publications addressing gene therapy for Hemophilia B, anticoagulant therapy for venous thromboembolism, and treatment practices for kaposiform hemangioendothelioma and vascular malformations. Dr. Crary also investigates pharmacokinetic properties of sclerotherapy agents and approaches to coagulopathy in patients with vascular anomalies. Her work has contributed to understanding long-term biological effects in sickle cell disease and defining pediatric refractory immune thrombocytopenia (ITP).
Dr. Crary is actively involved in medical education and mentorship, co-directing the UAMS Master’s in Clinical and Translational Sciences Scholarship Program and participating in the American Society of Hematology (ASH) Classical Hematology Mentorship Program. She earned her undergraduate degree from Washington University in St. Louis and her medical degree from Tulane University School of Medicine, followed by residency at Vanderbilt University and a fellowship at UT Southwestern Medical Center, where she also obtained a Master of Science in Clinical Science.
Metrics
- h-index: 20
- Publications: 103
- Citations: 2,103
Positions
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Professor, Pediatric Hematology-Oncology 2011–presentUniversity of Arkansas for Medical Sciences Pediatrics Institutional directory
Selected Publications
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Mental Health Evaluation in Patients with Vascular Malformations (2026)
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Bone mineral density, bone remodeling biomarkers, and hemostatic correlates in hemophilia and von Willebrand disease (2026)
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ReInspire: A Phase 2 Study of Mutant-Selective PI3Kα Inhibitor, RLY-2608, in Adults and Children with PIK3CA-Related Overgrowth Spectrum and Malformations Driven by PIK3CA Mutation (2026)
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HTRS2025.P1.27 Prevalence Vitamin D deficiency and risk factors for poor bone health in persons with Hemophilia A and B in Arkansas – A retrospective single institution study (2025)
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Recombinant von willebrand factor for perioperative management of bleeding in pediatric patients with severe von willebrand disease: Interim results from a phase 3 multicenter study and a phase 3b continuation study (2025)
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Multimodal neuroimaging and neurocognitive assessment in adolescents with and without sickle cell disease (2025)
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End-of-study results from the ICON3 pines trial, a phase 3, randomized trial of eltrombopag vs. standard first-line treatment for newly diagnosed immune thrombocytopenia in children (2025)
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Knowledge, interest, and willingness of hematologists and oncologists to care for adults with vascular anomalies (2025)
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Eltrombopag for Newly Diagnosed Pediatric Immune Thrombocytopenia Requiring Treatment (2025)
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Parental Adverse Childhood Experiences and Health Care Use Among Children With Sickle Cell Disease (2025)
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Pediatric hematology: selected topics (2025)
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The Functional Characterization of Venous Thromboembolic Disease (FUVID) study: rationale, design, and methods of a prospective, observational, multicenter study to evaluate mechanisms of exercise intolerance and dyspnea following pediatric pulmonary embolism (2024)
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Hemostasis and thrombosis risks and management in vascular anomalies (2024)
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Efficacy Findings in a Phase 3, Randomized Trial of Eltrombopag Vs. Standard First-Line Treatment for Newly Diagnosed Immune Thrombocytopenia in Children (2024)
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Hypercoagulability Evaluation in Pediatric Kidney Transplant Recipients to Optimize Outcomes (2024)
Grants & Funding
As listed on this researcher's institutional profile.
- CUMG UAMS College of Medicine
- GR034186-Crary-HRSA Great Plains Regional Hemophilia Network-UT University of Texas via UAMS ACHRI Flow Through
- Public Health Surveillance for the Prevention of Complications of Bleeding and Clotting UAMS ACHRI Flow Through
Collaboration Network
Top Collaborators
- Hematologic outcomes after total splenectomy and partial splenectomy for congenital hemolytic anemia
- Second‐line treatments in children with immune thrombocytopenia: Effect on platelet count and patient‐centered outcomes
- Clinical outcomes of splenectomy in children: Report of the splenectomy in congenital hemolytic anemia registry
- Physician decision making in selection of second‐line treatments in immune thrombocytopenia in children
- Pharmacokinetics and bioequivalence of a liquid formulation of hydroxyurea in children with sickle cell anemia
Showing 5 of 14 shared publications
- Second‐line treatments in children with immune thrombocytopenia: Effect on platelet count and patient‐centered outcomes
- Physician decision making in selection of second‐line treatments in immune thrombocytopenia in children
- What is in a name: defining pediatric refractory ITP
- Eltrombopag for Newly Diagnosed Pediatric Immune Thrombocytopenia Requiring Treatment
- The Functional Characterization of Venous Thromboembolic Disease (FUVID) study: rationale, design, and methods of a prospective, observational, multicenter study to evaluate mechanisms of exercise intolerance and dyspnea following pediatric pulmonary embolism
Showing 5 of 13 shared publications
- Effect of sirolimus on coagulopathy of slow‐flow vascular malformations
- Effectiveness and Safety of Treatment with Direct Oral Anticoagulant Rivaroxaban in Patients with Slow-Flow Vascular Malformations: A Case Series
- Short‐term side effects and patient‐reported outcomes of bleomycin sclerotherapy in vascular malformations
- Analyzing coagulation dynamics during treatment of vascular malformations with thromboelastography
- Pharmacokinetics of bleomycin sclerotherapy in patients with vascular malformations
Showing 5 of 13 shared publications
- Second‐line treatments in children with immune thrombocytopenia: Effect on platelet count and patient‐centered outcomes
- Intravenous low molecular weight iron dextran in children with iron deficiency anemia unresponsive to oral iron
- Physician decision making in selection of second‐line treatments in immune thrombocytopenia in children
- Splenectomy in Children With “Mild” Hereditary Spherocytosis
- Prominent Forehead Hematomas (“Goose-Eggs”) as an Initial Manifestation of Hemophilia
Showing 5 of 12 shared publications
- Second‐line treatments in children with immune thrombocytopenia: Effect on platelet count and patient‐centered outcomes
- Physician decision making in selection of second‐line treatments in immune thrombocytopenia in children
- What is in a name: defining pediatric refractory ITP
- Eltrombopag for Newly Diagnosed Pediatric Immune Thrombocytopenia Requiring Treatment
- Health Related Quality of Life and Fatigue Improve on Second Line Treatments in Pediatric Immune Thrombocytopenia (ITP)
Showing 5 of 12 shared publications
- Second‐line treatments in children with immune thrombocytopenia: Effect on platelet count and patient‐centered outcomes
- Physician decision making in selection of second‐line treatments in immune thrombocytopenia in children
- Eltrombopag for Newly Diagnosed Pediatric Immune Thrombocytopenia Requiring Treatment
- Health Related Quality of Life and Fatigue Improve on Second Line Treatments in Pediatric Immune Thrombocytopenia (ITP)
- Efficacy Findings in a Phase 3, Randomized Trial of Eltrombopag Vs. Standard First-Line Treatment for Newly Diagnosed Immune Thrombocytopenia in Children
Showing 5 of 11 shared publications
- Second‐line treatments in children with immune thrombocytopenia: Effect on platelet count and patient‐centered outcomes
- Physician decision making in selection of second‐line treatments in immune thrombocytopenia in children
- What is in a name: defining pediatric refractory ITP
- Eltrombopag for Newly Diagnosed Pediatric Immune Thrombocytopenia Requiring Treatment
- Health Related Quality of Life and Fatigue Improve on Second Line Treatments in Pediatric Immune Thrombocytopenia (ITP)
Showing 5 of 11 shared publications
- Second‐line treatments in children with immune thrombocytopenia: Effect on platelet count and patient‐centered outcomes
- Physician decision making in selection of second‐line treatments in immune thrombocytopenia in children
- Health Related Quality of Life and Fatigue Improve on Second Line Treatments in Pediatric Immune Thrombocytopenia (ITP)
- Physician Factors Determining Treatment Decisions in Selecting Second Line Agents for Pediatric ITP
- Comparison of Bleeding Tools in a Cohort of Pediatric Patients with ITP: Data from the Pediatric ITP Consortium of North America ICON1 Study
Showing 5 of 8 shared publications
- Second‐line treatments in children with immune thrombocytopenia: Effect on platelet count and patient‐centered outcomes
- Physician decision making in selection of second‐line treatments in immune thrombocytopenia in children
- What is in a name: defining pediatric refractory ITP
- Health Related Quality of Life and Fatigue Improve on Second Line Treatments in Pediatric Immune Thrombocytopenia (ITP)
- Physician Factors Determining Treatment Decisions in Selecting Second Line Agents for Pediatric ITP
Showing 5 of 8 shared publications
- Second‐line treatments in children with immune thrombocytopenia: Effect on platelet count and patient‐centered outcomes
- Physician decision making in selection of second‐line treatments in immune thrombocytopenia in children
- What is in a name: defining pediatric refractory ITP
- Health Related Quality of Life and Fatigue Improve on Second Line Treatments in Pediatric Immune Thrombocytopenia (ITP)
- Physician Factors Determining Treatment Decisions in Selecting Second Line Agents for Pediatric ITP
Showing 5 of 8 shared publications
- Second‐line treatments in children with immune thrombocytopenia: Effect on platelet count and patient‐centered outcomes
- Physician decision making in selection of second‐line treatments in immune thrombocytopenia in children
- Health Related Quality of Life and Fatigue Improve on Second Line Treatments in Pediatric Immune Thrombocytopenia (ITP)
- Physician Factors Determining Treatment Decisions in Selecting Second Line Agents for Pediatric ITP
- Comparison of Bleeding Tools in a Cohort of Pediatric Patients with ITP: Data from the Pediatric ITP Consortium of North America ICON1 Study
Showing 5 of 8 shared publications
- Second‐line treatments in children with immune thrombocytopenia: Effect on platelet count and patient‐centered outcomes
- Physician decision making in selection of second‐line treatments in immune thrombocytopenia in children
- Treatment practices and response in kaposiform hemangioendothelioma: A multicenter cohort study
- Health Related Quality of Life and Fatigue Improve on Second Line Treatments in Pediatric Immune Thrombocytopenia (ITP)
- Physician Factors Determining Treatment Decisions in Selecting Second Line Agents for Pediatric ITP
Showing 5 of 8 shared publications
- Physician decision making in selection of second‐line treatments in immune thrombocytopenia in children
- Eltrombopag for Newly Diagnosed Pediatric Immune Thrombocytopenia Requiring Treatment
- Efficacy Findings in a Phase 3, Randomized Trial of Eltrombopag Vs. Standard First-Line Treatment for Newly Diagnosed Immune Thrombocytopenia in Children
- Comparison of Bleeding Tools in a Cohort of Pediatric Patients with ITP: Data from the Pediatric ITP Consortium of North America ICON1 Study
- Physician decision making in selection of second-line treatments in immune thrombocytopenia in children.
Showing 5 of 8 shared publications
- Second‐line treatments in children with immune thrombocytopenia: Effect on platelet count and patient‐centered outcomes
- Physician decision making in selection of second‐line treatments in immune thrombocytopenia in children
- Health Related Quality of Life and Fatigue Improve on Second Line Treatments in Pediatric Immune Thrombocytopenia (ITP)
- Physician Factors Determining Treatment Decisions in Selecting Second Line Agents for Pediatric ITP
- Comparison of Bleeding Tools in a Cohort of Pediatric Patients with ITP: Data from the Pediatric ITP Consortium of North America ICON1 Study
Showing 5 of 7 shared publications
- Second‐line treatments in children with immune thrombocytopenia: Effect on platelet count and patient‐centered outcomes
- Eltrombopag for Newly Diagnosed Pediatric Immune Thrombocytopenia Requiring Treatment
- Health Related Quality of Life and Fatigue Improve on Second Line Treatments in Pediatric Immune Thrombocytopenia (ITP)
- Efficacy Findings in a Phase 3, Randomized Trial of Eltrombopag Vs. Standard First-Line Treatment for Newly Diagnosed Immune Thrombocytopenia in Children
- Physician Factors Determining Treatment Decisions in Selecting Second Line Agents for Pediatric ITP
Showing 5 of 7 shared publications
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