Biography and Research Information
OverviewAI-generated summary
Srihari Shankar's research focuses on understanding the molecular mechanisms underlying cellular processes, including replication, cargo trafficking, and protein allostery. His work investigates the molecular biology of cancer and other disease states. Shankar has published on the structural basis for the regulation of Rho inactivation by p50RhoGAP, the enzymatic activity of the HACE1 HECT-type E3 ligase, and a novel allosteric site in human kidney-type glutaminase. His recent publications also explore the regulation of CHIP E3 ligase-mediated ubiquitination and the distinct roles of specific amino acid residues in the BCH domain of yeast p50RhoGAP. Additionally, he has contributed to structural studies of the GINS tetramer from *Saccharolobus solfataricus*.
Metrics
- h-index: 4
- Publications: 8
- Citations: 46
Selected Publications
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Structure of the <i>Saccharolobus solfataricus</i> GINS tetramer (2025)
Collaboration Network
Top Collaborators
- Structure of the <i>Saccharolobus solfataricus</i> GINS tetramer
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