Research Areas
Biography and Research Information
OverviewAI-generated summary
Stephanie M. Sauve's research investigates the conformational dynamics of biological molecules, particularly focusing on the HIV-1 envelope glycoprotein. Her work integrates computational methods, such as molecular dynamics (MD) simulations, with experimental techniques, including single-molecule Förster resonance energy transfer (smFRET) spectroscopy. Sauve has explored methods for simulating smFRET data, considering protein conformational dynamics and utilizing implicit dye sampling techniques. Her publications include atomic-level characterizations of HIV-1 envelope glycoprotein states using MD simulations and the application of bioorthogonal click labeling for in-virus single-molecule imaging. Sauve collaborates with researchers at the University of Arkansas at Fayetteville, including Mahmoud Moradi and James Losey, on shared publications related to these research areas.
Metrics
- h-index: 3
- Publications: 6
- Citations: 45
Selected Publications
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Predicting Binding Affinities for the Binding Domain of Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel Isoforms Using Free-Energy Perturbation (2026)
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BPS2026 – Absolute physics-based binding free-energy estimation of antibody-antigen complexes (2026)
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Simulating Freely Diffusing Single-Molecule FRET Data with Consideration of Protein Conformational Dynamics (2026)
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Integrating Molecular Dynamics Simulations and Single-molecule FRET Spectroscopy: From Computational FRET Estimation to Experimental Data Interpretation (2026)
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BPS2025 - An integrated smFRET-MD approach to study the conformational dynamics of the HIV-1 Env glycoprotein by utilizing implicit dye sampling technique (2025)
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Atomic-level characterization of HIV-1 envelope glycoprotein conformational states using molecular dynamics simulations (2024)
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Bioorthogonal click labeling of an amber-free HIV-1 provirus for in-virus single molecule imaging (2024)
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Ins and Outs of Rocker Switch Mechanism in Major Facilitator Superfamily of Transporters (2023)
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Atomic-level characterization of the human immunodeficiency virus type 1 envelope glycoproteins using molecular dynamic simulations (2023)
Collaboration Network
Top Collaborators
- Atomic-level characterization of the human immunodeficiency virus type 1 envelope glycoproteins using molecular dynamic simulations
- Atomic-level characterization of HIV-1 envelope glycoprotein conformational states using molecular dynamics simulations
- BPS2025 - An integrated smFRET-MD approach to study the conformational dynamics of the HIV-1 Env glycoprotein by utilizing implicit dye sampling technique
- Atomic-level characterization of the human immunodeficiency virus type 1 envelope glycoproteins using molecular dynamic simulations
- Atomic-level characterization of HIV-1 envelope glycoprotein conformational states using molecular dynamics simulations
- BPS2025 - An integrated smFRET-MD approach to study the conformational dynamics of the HIV-1 Env glycoprotein by utilizing implicit dye sampling technique
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