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Confirmed
Presence
Current · Arkansas
Last published
2025
Sources
OpenAlex · ORCID
Refreshed
2026-10-08
T
Timothy A. Evans
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Federal Grant PI
High Impact
Associate Professor
Also affiliated: Indiana University Bloomington (2004–2008); Indiana University (2004–2008); University of Pennsylvania (2010–2015)
12 h-index
36 pubs
608 cited
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Timothy A. Evans investigates axon guidance mechanisms in the fruit fly *Drosophila*. His work focuses on the Robo receptor family, specifically Robo2 and Robo3, examining how these proteins regulate the formation of neural circuits. His research has explored the functional domains of Robo2, including the Ig1 domain, and its requirement for various guidance activities. Evans has also studied the signaling and regulation of Robo receptors by comparing *Drosophila* Robo1 with its counterpart in *C. elegans*, SAX-3, highlighting conserved and divergent aspects between these species.
His laboratory also characterizes regulatory elements, such as enhancer fragments, within the *Drosophila robo2* gene. Recent publications also detail methodologies for dissecting and microscopy of *Drosophila* embryos and for the collection, fixation, and antibody staining of these embryos, indicating a focus on experimental techniques within developmental neurobiology. Furthermore, Evans has contributed to understanding the evolution of wing scaling in *Drosophila* species through the study of *cis*-regulatory sequences.
Evans has received federal funding from the NIH/National Institute of Neurological Disorders and Stroke for his research on the functional analysis of the *Drosophila* axon guidance receptor Robo2. He holds a h-index of 26 with over 3,500 citations across his 68 publications. He actively collaborates with researchers at the University of Arkansas at Fayetteville, including LaFreda J. Howard, Marie C. Reichert, Keity J. Farfán‐Pira, and Trent Daiber.
Metrics
- h-index: 12
- Publications: 36
- Citations: 608
Positions
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Associate Professor 2019–presentUniversity of Arkansas at Fayetteville Biological Sciences ORCID
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Assistant Professor 2013–2019University of Arkansas Biological Sciences ORCID
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Postdoc 2006–2013University of Pennsylvania Neuroscience ORCID
Selected Publications
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Evolutionary conservation of midline axon guidance activity between Drosophila and Tribolium Frazzled (2025)
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Evolutionary conservation of midline repulsive signaling by Robo family receptors in flies and mice (2025)
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Evolutionary conservation of midline repulsive signaling by Robo family receptors in flies and mice (2025)
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Slit-independent guidance of longitudinal axons by Drosophila Robo3 (2025)
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Evolutionary conservation of midline axon guidance activity between Drosophila and Tribolium Frazzled (2024)
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Drosophila Robo3 guides longitudinal axons partially independently of its cytodomain (2024)
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Ventral Nerve Cord Dissection and Microscopy ofDrosophilaEmbryos (2023)
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Collection, Fixation, and Antibody Staining ofDrosophilaEmbryos (2023)
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Analysis of Axon Guidance in theDrosophilaEmbryo (2023)
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Slit-independent guidance of longitudinal axons by Drosophila Robo3 (2023)
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A cis-regulatory sequence of the selector gene vestigial drives the evolution of wing scaling in Drosophila species (2023)
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Characterization of enhancer fragments in Drosophila robo2 (2022)
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Characterization of enhancer fragments in Drosophila robo2 (2022)
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The vestigial Quadrant Enhancer is dispensable for pattern formation and development of the Drosophila wing (2022)
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A cis -regulatory sequence of the wing selector gene, vestigial , drives the evolution of scaling relationships in Drosophila species (2022)
Federal Grants 1 $443,483 total
NIH
Contact PI
Jul 2016 - Jun 2027
Functional analysis of the Drosophila axon guidance receptor Robo2
Collaboration Network
Top Collaborators
Haley E. Brown
University of Arkansas at Fayetteville (US)
8 shared publications
- Midline axon guidance in the Drosophila embryonic central nervous system
- Slit Binding via the Ig1 Domain Is Essential for Midline Repulsion by Drosophila Robo1 but Dispensable for Receptor Expression, Localization, and Regulation in Vivo
- In Vivo Functional Analysis of Drosophila Robo1 Fibronectin Type-III Repeats
- In vivo functional analysis of Drosophila Robo1 immunoglobulin-like domains
- Minimal structural elements required for midline repulsive signaling and regulation of Drosophila Robo1
Showing 5 of 8 shared publications
Marie C. Reichert
University of Arkansas at Fayetteville
7 shared publications
In database
- Slit Binding via the Ig1 Domain Is Essential for Midline Repulsion by Drosophila Robo1 but Dispensable for Receptor Expression, Localization, and Regulation in Vivo
- In Vivo Functional Analysis of Drosophila Robo1 Fibronectin Type-III Repeats
- In vivo functional analysis of Drosophila Robo1 immunoglobulin-like domains
- The Slit‐binding Ig1 domain is required for multiple axon guidance activities of Drosophila Robo2
- Characterization of enhancer fragments in Drosophila robo2
Showing 5 of 7 shared publications
LaFreda J. Howard
University of Arkansas at Fayetteville
5 shared publications
In database
- Midline axon guidance in the Drosophila embryonic central nervous system
- The Slit‐binding Ig1 domain is required for multiple axon guidance activities of Drosophila Robo2
- Slit-independent guidance of longitudinal axons by Drosophila Robo3
- Slit-independent guidance of longitudinal axons by Drosophila Robo3
- The Slit-binding Ig1 domain is required for multiple axon guidance activities of Drosophila Robo2
Greg J. Bashaw
University of Pennsylvania (US)
4 shared publications
- Robo2 acts in trans to inhibit Slit-Robo1 repulsion in pre-crossing commissural axons
- Conserved and divergent aspects of Robo receptor signaling and regulation between Drosophila Robo1 and C. elegans SAX-3
- Author response: Robo2 acts in trans to inhibit Slit-Robo1 repulsion in pre-crossing commissural axons
- Conserved and divergent aspects of Robo receptor signaling and regulation between Drosophila Robo1 and C. elegans SAX-3
Trent Daiber
University of Arkansas at Fayetteville
4 shared publications
In database
- Conserved and divergent aspects of Robo receptor signaling and regulation between Drosophila Robo1 and C. elegans SAX-3
- Evolutionary conservation of midline repulsive signaling by Robo family receptors in flies and mice
- Conserved and divergent aspects of Robo receptor signaling and regulation between Drosophila Robo1 and C. elegans SAX-3
- Evolutionary conservation of midline repulsive signaling by Robo family receptors in flies and mice
Benjamin C. Wadsworth
University of Arkansas at Fayetteville
3 shared publications
In database
- Midline axon guidance in the Drosophila embryonic central nervous system
- Evolutionary conservation of midline axon guidance activity between Drosophila and Tribolium Frazzled
- Evolutionary conservation of midline axon guidance activity between Drosophila and Tribolium Frazzled
Keity J. Farfán‐Pira
Instituto Politécnico Nacional
3 shared publications
In database
- A cis-regulatory sequence of the selector gene vestigial drives the evolution of wing scaling in Drosophila species
- The vestigial Quadrant Enhancer is dispensable for pattern formation and development of the Drosophila wing
- A cis -regulatory sequence of the wing selector gene, vestigial , drives the evolution of scaling relationships in Drosophila species
Teresa I. Martínez-Cuevas
Instituto Politécnico Nacional (MX)
3 shared publications
- A cis-regulatory sequence of the selector gene vestigial drives the evolution of wing scaling in Drosophila species
- The vestigial Quadrant Enhancer is dispensable for pattern formation and development of the Drosophila wing
- A cis -regulatory sequence of the wing selector gene, vestigial , drives the evolution of scaling relationships in Drosophila species
Marcos Nahmad
Instituto Politécnico Nacional (MX)
3 shared publications
- A cis-regulatory sequence of the selector gene vestigial drives the evolution of wing scaling in Drosophila species
- The vestigial Quadrant Enhancer is dispensable for pattern formation and development of the Drosophila wing
- A cis -regulatory sequence of the wing selector gene, vestigial , drives the evolution of scaling relationships in Drosophila species
Thomas Kidd
University of Nevada, Reno (US)
3 shared publications
- Collection, Fixation, and Antibody Staining ofDrosophilaEmbryos
- Ventral Nerve Cord Dissection and Microscopy ofDrosophilaEmbryos
- Analysis of Axon Guidance in theDrosophilaEmbryo
Celine Santiago
University of Pennsylvania (US)
2 shared publications
- Robo2 acts in trans to inhibit Slit-Robo1 repulsion in pre-crossing commissural axons
- Author response: Robo2 acts in trans to inhibit Slit-Robo1 repulsion in pre-crossing commissural axons
Elise Arbeille
University of Pennsylvania (US)
2 shared publications
- Robo2 acts in trans to inhibit Slit-Robo1 repulsion in pre-crossing commissural axons
- Author response: Robo2 acts in trans to inhibit Slit-Robo1 repulsion in pre-crossing commissural axons
Christine J. VanderZwan-Butler
University of Pennsylvania (US)
2 shared publications
- Conserved and divergent aspects of Robo receptor signaling and regulation between Drosophila Robo1 and C. elegans SAX-3
- Conserved and divergent aspects of Robo receptor signaling and regulation between Drosophila Robo1 and C. elegans SAX-3
Gina Hauptman
University of Arkansas at Fayetteville
2 shared publications
In database
- Characterization of enhancer fragments in Drosophila robo2
- Characterization of enhancer fragments in Drosophila robo2
Muna A. Abdal Rhida
University of Wasit
2 shared publications
In database
- Characterization of enhancer fragments in Drosophila robo2
- Characterization of enhancer fragments in Drosophila robo2
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