Timothy A. Evans
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Associate Professor
Also affiliated: University of North Carolina at Chapel Hill (1985–1989); Australian National University (1980); Queen's University Belfast (1993–1999); Centre National de la Recherche Scientifique (1994); Inserm (1994); Baylor College of Medicine (1993); Washington University in St. Louis (1986); Montana State University (1993); American Pharmacists Association (1994); Yale University (1989); University of California San Diego (1985); Acentech (United States) (1991–1992); Indiana University Bloomington (2004–2008); Paris Cardiovascular Research Center (1994); Smiths Detection (Canada) (1989); Neurological Surgery (1989); Indiana University (2004); University of Pennsylvania (2010–2015); California State Polytechnic University (1979)
Faculty Researcher
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Timothy A. Evans investigates axon guidance mechanisms in the fruit fly *Drosophila*. His work focuses on the Robo receptor family, specifically Robo2 and Robo3, examining how these proteins regulate the formation of neural circuits. His research has explored the functional domains of Robo2, including the Ig1 domain, and its requirement for various guidance activities. Evans has also studied the signaling and regulation of Robo receptors by comparing *Drosophila* Robo1 with its counterpart in *C. elegans*, SAX-3, highlighting conserved and divergent aspects between these species.
His laboratory also characterizes regulatory elements, such as enhancer fragments, within the *Drosophila robo2* gene. Recent publications also detail methodologies for dissecting and microscopy of *Drosophila* embryos and for the collection, fixation, and antibody staining of these embryos, indicating a focus on experimental techniques within developmental neurobiology. Furthermore, Evans has contributed to understanding the evolution of wing scaling in *Drosophila* species through the study of *cis*-regulatory sequences.
Evans has received federal funding from the NIH/National Institute of Neurological Disorders and Stroke for his research on the functional analysis of the *Drosophila* axon guidance receptor Robo2. He holds a h-index of 26 with over 3,500 citations across his 68 publications. He actively collaborates with researchers at the University of Arkansas at Fayetteville, including LaFreda J. Howard, Marie C. Reichert, Keity J. Farfán‐Pira, and Trent Daiber.
Metrics
- h-index: 26
- Publications: 68
- Citations: 3,619
Selected Publications
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Evolutionary conservation of midline axon guidance activity between Drosophila and Tribolium Frazzled (2025)
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Evolutionary conservation of midline repulsive signaling by Robo family receptors in flies and mice (2025)
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Evolutionary conservation of midline repulsive signaling by Robo family receptors in flies and mice (2025)
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Slit-independent guidance of longitudinal axons by Drosophila Robo3 (2025)
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Evolutionary conservation of midline axon guidance activity between <i>Drosophila</i> and <i>Tribolium</i> Frazzled (2024)
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Drosophila Robo3 guides longitudinal axons partially independently of its cytodomain (2024)
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Ventral Nerve Cord Dissection and Microscopy of<i>Drosophila</i>Embryos (2023)
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Collection, Fixation, and Antibody Staining of<i>Drosophila</i>Embryos (2023)
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Analysis of Axon Guidance in the<i>Drosophila</i>Embryo (2023)
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Slit-independent guidance of longitudinal axons by <i>Drosophila</i> Robo3 (2023)
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A <i>cis</i>-regulatory sequence of the selector gene <i>vestigial</i> drives the evolution of wing scaling in <i>Drosophila</i> species (2023)
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Characterization of enhancer fragments in <i>Drosophila robo2</i> (2022)
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Characterization of enhancer fragments in <i>Drosophila robo2</i> (2022)
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The vestigial Quadrant Enhancer is dispensable for pattern formation and development of the Drosophila wing (2022)
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A <i>cis</i> -regulatory sequence of the wing selector gene, <i>vestigial</i> , drives the evolution of scaling relationships in <i>Drosophila</i> species (2022)
Federal Grants 1 $443,483 total
Functional analysis of the Drosophila axon guidance receptor Robo2
Collaboration Network
Top Collaborators
- The Slit‐binding Ig1 domain is required for multiple axon guidance activities of <i>Drosophila</i> Robo2
- Slit-independent guidance of longitudinal axons by <i>Drosophila</i> Robo3
- Slit-independent guidance of longitudinal axons by Drosophila Robo3
- The Slit-binding Ig1 domain is required for multiple axon guidance activities of <i>Drosophila</i> Robo2
- The Slit‐binding Ig1 domain is required for multiple axon guidance activities of <i>Drosophila</i> Robo2
- Characterization of enhancer fragments in <i>Drosophila robo2</i>
- The Slit-binding Ig1 domain is required for multiple axon guidance activities of <i>Drosophila</i> Robo2
- Characterization of enhancer fragments in <i>Drosophila robo2</i>
- Conserved and divergent aspects of Robo receptor signaling and regulation between <i>Drosophila</i> Robo1 and <i>C. elegans</i> SAX-3
- Evolutionary conservation of midline repulsive signaling by Robo family receptors in flies and mice
- Evolutionary conservation of midline repulsive signaling by Robo family receptors in flies and mice
- A <i>cis</i>-regulatory sequence of the selector gene <i>vestigial</i> drives the evolution of wing scaling in <i>Drosophila</i> species
- The vestigial Quadrant Enhancer is dispensable for pattern formation and development of the Drosophila wing
- A <i>cis</i> -regulatory sequence of the wing selector gene, <i>vestigial</i> , drives the evolution of scaling relationships in <i>Drosophila</i> species
- A <i>cis</i>-regulatory sequence of the selector gene <i>vestigial</i> drives the evolution of wing scaling in <i>Drosophila</i> species
- The vestigial Quadrant Enhancer is dispensable for pattern formation and development of the Drosophila wing
- A <i>cis</i> -regulatory sequence of the wing selector gene, <i>vestigial</i> , drives the evolution of scaling relationships in <i>Drosophila</i> species
- A <i>cis</i>-regulatory sequence of the selector gene <i>vestigial</i> drives the evolution of wing scaling in <i>Drosophila</i> species
- The vestigial Quadrant Enhancer is dispensable for pattern formation and development of the Drosophila wing
- A <i>cis</i> -regulatory sequence of the wing selector gene, <i>vestigial</i> , drives the evolution of scaling relationships in <i>Drosophila</i> species
- Collection, Fixation, and Antibody Staining of<i>Drosophila</i>Embryos
- Ventral Nerve Cord Dissection and Microscopy of<i>Drosophila</i>Embryos
- Analysis of Axon Guidance in the<i>Drosophila</i>Embryo
- Characterization of enhancer fragments in <i>Drosophila robo2</i>
- Characterization of enhancer fragments in <i>Drosophila robo2</i>
- Characterization of enhancer fragments in <i>Drosophila robo2</i>
- Characterization of enhancer fragments in <i>Drosophila robo2</i>
- Slit-independent guidance of longitudinal axons by <i>Drosophila</i> Robo3
- Slit-independent guidance of longitudinal axons by Drosophila Robo3
- Slit-independent guidance of longitudinal axons by <i>Drosophila</i> Robo3
- Slit-independent guidance of longitudinal axons by Drosophila Robo3
- Slit-independent guidance of longitudinal axons by <i>Drosophila</i> Robo3
- Slit-independent guidance of longitudinal axons by Drosophila Robo3
- Evolutionary conservation of midline axon guidance activity between <i>Drosophila</i> and <i>Tribolium</i> Frazzled
- Evolutionary conservation of midline axon guidance activity between Drosophila and Tribolium Frazzled
- Evolutionary conservation of midline axon guidance activity between <i>Drosophila</i> and <i>Tribolium</i> Frazzled
- Evolutionary conservation of midline axon guidance activity between Drosophila and Tribolium Frazzled
- Evolutionary conservation of midline repulsive signaling by Robo family receptors in flies and mice
- Evolutionary conservation of midline repulsive signaling by Robo family receptors in flies and mice
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