T
Timothy A. Evans Data-verified
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Federal Grant PI
High Impact
Associate Professor
faculty
26 h-index
68 pubs
3,598 cited
Research Areas
Links
Biography and Research Information
OverviewAI-generated summary
Timothy A. Evans investigates axon guidance mechanisms in the fruit fly *Drosophila*. His work focuses on the Robo receptor family, specifically Robo2 and Robo3, examining how these proteins regulate the formation of neural circuits. His research has explored the functional domains of Robo2, including the Ig1 domain, and its requirement for various guidance activities. Evans has also studied the signaling and regulation of Robo receptors by comparing *Drosophila* Robo1 with its counterpart in *C. elegans*, SAX-3, highlighting conserved and divergent aspects between these species.
His laboratory also characterizes regulatory elements, such as enhancer fragments, within the *Drosophila robo2* gene. Recent publications also detail methodologies for dissecting and microscopy of *Drosophila* embryos and for the collection, fixation, and antibody staining of these embryos, indicating a focus on experimental techniques within developmental neurobiology. Furthermore, Evans has contributed to understanding the evolution of wing scaling in *Drosophila* species through the study of *cis*-regulatory sequences.
Evans has received federal funding from the NIH/National Institute of Neurological Disorders and Stroke for his research on the functional analysis of the *Drosophila* axon guidance receptor Robo2. He holds a h-index of 26 with over 3,500 citations across his 68 publications. He actively collaborates with researchers at the University of Arkansas at Fayetteville, including LaFreda J. Howard, Marie C. Reichert, Keity J. Farfán‐Pira, and Trent Daiber.
Metrics
- h-index: 26
- Publications: 68
- Citations: 3,598
Selected Publications
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Evolutionary conservation of midline axon guidance activity between Drosophila and Tribolium Frazzled (2025)
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Evolutionary conservation of midline repulsive signaling by Robo family receptors in flies and mice (2025)
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Evolutionary conservation of midline repulsive signaling by Robo family receptors in flies and mice (2025)
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Slit-independent guidance of longitudinal axons by Drosophila Robo3 (2025)
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Evolutionary conservation of midline axon guidance activity between <i>Drosophila</i> and <i>Tribolium</i> Frazzled (2024)
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Drosophila Robo3 guides longitudinal axons partially independently of its cytodomain (2024)
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Ventral Nerve Cord Dissection and Microscopy of<i>Drosophila</i>Embryos (2023)
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Collection, Fixation, and Antibody Staining of<i>Drosophila</i>Embryos (2023)
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Analysis of Axon Guidance in the<i>Drosophila</i>Embryo (2023)
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Slit-independent guidance of longitudinal axons by <i>Drosophila</i> Robo3 (2023)
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A <i>cis</i>-regulatory sequence of the selector gene <i>vestigial</i> drives the evolution of wing scaling in <i>Drosophila</i> species (2023)
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Characterization of enhancer fragments in <i>Drosophila robo2</i> (2022)
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Characterization of enhancer fragments in <i>Drosophila robo2</i> (2022)
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The vestigial Quadrant Enhancer is dispensable for pattern formation and development of the Drosophila wing (2022)
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A <i>cis</i> -regulatory sequence of the wing selector gene, <i>vestigial</i> , drives the evolution of scaling relationships in <i>Drosophila</i> species (2022)
Federal Grants 1 $443,483 total
NIH/National Institute of Neurological Disorders and Stroke
Contact PI
Jul 2016 - Jun 2026
Functional analysis of the Drosophila axon guidance receptor Robo2
Collaboration Network
Top Collaborators
LaFreda J. Howard
University of Arkansas at Fayetteville
4 shared publications
In database
- The Slit‐binding Ig1 domain is required for multiple axon guidance activities of <i>Drosophila</i> Robo2
- Slit-independent guidance of longitudinal axons by <i>Drosophila</i> Robo3
- Slit-independent guidance of longitudinal axons by Drosophila Robo3
- The Slit-binding Ig1 domain is required for multiple axon guidance activities of <i>Drosophila</i> Robo2
Marie C. Reichert
University of Arkansas at Fayetteville
4 shared publications
In database
- The Slit‐binding Ig1 domain is required for multiple axon guidance activities of <i>Drosophila</i> Robo2
- Characterization of enhancer fragments in <i>Drosophila robo2</i>
- The Slit-binding Ig1 domain is required for multiple axon guidance activities of <i>Drosophila</i> Robo2
- Characterization of enhancer fragments in <i>Drosophila robo2</i>
Trent Daiber
University of Arkansas at Fayetteville
3 shared publications
In database
- Conserved and divergent aspects of Robo receptor signaling and regulation between <i>Drosophila</i> Robo1 and <i>C. elegans</i> SAX-3
- Evolutionary conservation of midline repulsive signaling by Robo family receptors in flies and mice
- Evolutionary conservation of midline repulsive signaling by Robo family receptors in flies and mice
Keity J. Farfán‐Pira
Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional
3 shared publications
In database
- A <i>cis</i>-regulatory sequence of the selector gene <i>vestigial</i> drives the evolution of wing scaling in <i>Drosophila</i> species
- The vestigial Quadrant Enhancer is dispensable for pattern formation and development of the Drosophila wing
- A <i>cis</i> -regulatory sequence of the wing selector gene, <i>vestigial</i> , drives the evolution of scaling relationships in <i>Drosophila</i> species
Teresa I. Martínez-Cuevas
Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (MX)
3 shared publications
- A <i>cis</i>-regulatory sequence of the selector gene <i>vestigial</i> drives the evolution of wing scaling in <i>Drosophila</i> species
- The vestigial Quadrant Enhancer is dispensable for pattern formation and development of the Drosophila wing
- A <i>cis</i> -regulatory sequence of the wing selector gene, <i>vestigial</i> , drives the evolution of scaling relationships in <i>Drosophila</i> species
Marcos Nahmad
Instituto Politécnico Nacional (MX)
3 shared publications
- A <i>cis</i>-regulatory sequence of the selector gene <i>vestigial</i> drives the evolution of wing scaling in <i>Drosophila</i> species
- The vestigial Quadrant Enhancer is dispensable for pattern formation and development of the Drosophila wing
- A <i>cis</i> -regulatory sequence of the wing selector gene, <i>vestigial</i> , drives the evolution of scaling relationships in <i>Drosophila</i> species
Thomas Kidd
University of Nevada, Reno (US)
3 shared publications
- Collection, Fixation, and Antibody Staining of<i>Drosophila</i>Embryos
- Ventral Nerve Cord Dissection and Microscopy of<i>Drosophila</i>Embryos
- Analysis of Axon Guidance in the<i>Drosophila</i>Embryo
Gina Hauptman
University of Arkansas at Fayetteville
2 shared publications
In database
- Characterization of enhancer fragments in <i>Drosophila robo2</i>
- Characterization of enhancer fragments in <i>Drosophila robo2</i>
Muna A. Abdal Rhida
University of Wasit
2 shared publications
In database
- Characterization of enhancer fragments in <i>Drosophila robo2</i>
- Characterization of enhancer fragments in <i>Drosophila robo2</i>
Abigail Carranza
University of Arkansas at Fayetteville
2 shared publications
In database
- Slit-independent guidance of longitudinal axons by <i>Drosophila</i> Robo3
- Slit-independent guidance of longitudinal axons by Drosophila Robo3
Haley E. Brown
University of Arkansas at Fayetteville (US)
2 shared publications
- Slit-independent guidance of longitudinal axons by <i>Drosophila</i> Robo3
- Slit-independent guidance of longitudinal axons by Drosophila Robo3
Ayawovi Selom Ametepe
University of Arkansas at Fayetteville
2 shared publications
In database
- Slit-independent guidance of longitudinal axons by <i>Drosophila</i> Robo3
- Slit-independent guidance of longitudinal axons by Drosophila Robo3
Piyasi Ghosh
University of Arkansas at Fayetteville
2 shared publications
In database
- Evolutionary conservation of midline axon guidance activity between <i>Drosophila</i> and <i>Tribolium</i> Frazzled
- Evolutionary conservation of midline axon guidance activity between Drosophila and Tribolium Frazzled
Benjamin C. Wadsworth
University of Arkansas at Fayetteville
2 shared publications
In database
- Evolutionary conservation of midline axon guidance activity between <i>Drosophila</i> and <i>Tribolium</i> Frazzled
- Evolutionary conservation of midline axon guidance activity between Drosophila and Tribolium Frazzled
Allison Loy
University of Arkansas at Fayetteville
2 shared publications
In database
- Evolutionary conservation of midline repulsive signaling by Robo family receptors in flies and mice
- Evolutionary conservation of midline repulsive signaling by Robo family receptors in flies and mice
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