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Presence
Current · Arkansas
Last published
2021
Sources
OpenAlex · ORCID
Refreshed
2026-10-08
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Kristopher A. Bottoms
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
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2 h-index
9 pubs
92 cited
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Kristopher A. Bottoms' research primarily investigates predictors of patient outcomes and the gut microbiome in both animal and human health contexts. His work includes studying plasma nuclear and mitochondrial DNA levels as indicators for severe sepsis patients in emergency rooms, and examining the characteristics and prognostic predictors of unplanned hospital admissions following emergency department discharge. Bottoms has also explored the differences in using serum lactate levels to predict mortality from sepsis in elderly versus non-elderly patients in the emergency department.
In parallel, his research extends to animal models, specifically swine. This work focuses on the swine gut microbiome, examining its development from birth to market and how factors like early agricultural soil exposure and dietary interventions, such as organic acids and yeast products, influence gut maturation, growth performance, and immune parameters. Bottoms has a h-index of 2 across 9 publications, with key collaborators at the University of Arkansas at Fayetteville.
Metrics
- h-index: 2
- Publications: 9
- Citations: 92
Selected Publications
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Lactiplantibacillus plantarum promotes intestinal goblet cell differentiation via indole-3-lactic acid–AHR signaling in pigs (2026)
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Advances in veterinary drug and vaccine delivery: from conventional delivery methods to innovative transdermal approaches (2026)
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Longitudinal Modulation of the Gut Microbiome and Growth Performance by Phytochemicals as Antibiotic Alternatives in Swine Production (2026)
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127 The impact of Phytozen® on intestinal integrity following weaning (2025)
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233 Effect of fiber and stimbiotic on growth performance and the gut microbiome in pigs challenged with F18 enterotoxigenic Escherichia coli (ETEC) (2025)
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PSII-2 Longitudinal investigation of reducing growth during gilt development period and 25(OH)D3 on gilt’s complete blood cell counts from 9 weeks of ages through 4 parity cycles (2025)
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The sow vaginal and gut microbiota associated with longevity and reproductive performance (2025)
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PSLBI-20 Dynamic response of piglets fed different sources and levels of fiber during an enterotoxigenic Escherichia coli (ETEC) challenge in the post-weaning transition (2024)
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PSIII-28 Evaluation of tissue and plasma meloxicam concentrations using a microneedle patch for drug delivery (2024)
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99 Phytochemicals as medical growth promoter replacement on growth performance in wean to finisher pigs (2024)
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PSIV-A-3 Effect of fiber and stimbiotic on growth performance and the gut microbiome in pigs challenged with F18 enterotoxigenic Escherichia coli (ETEC) (2024)
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PSII-3 Evaluation of a microneedle patch for the delivery of meloxicam in a veterinary application (2024)
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A cooperative study assessing the effects of a second iron injection administered before weaning on growth performance, hematological status, and tissue mineral concentrations of nursery pigs* (2024)
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PSVI-18 Effects of Sow Vocalization and Scent on Complete Blood Cell Count During Early Weaning Period (2023)
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PSIV-1 Nutrient Intervention During Gilt Development Leads to Effects on Progeny Growth Responses (2023)
Collaboration Network
Top Collaborators
Charles V Maxwell
University of Arkansas at Fayetteville
30 shared publications
In database
- Longitudinal investigation of the swine gut microbiome from birth to market reveals stage and growth performance associated bacteria
- Influence of a whole yeast product (Pichia guilliermondii) fed throughout gestation and lactation on performance and immune parameters of the sow and litter
- Comprehensive Cultivation of the Swine Gut Microbiome Reveals High Bacterial Diversity and Guides Bacterial Isolation in Pigs
- Effect of Lactylate and Bacillus subtilis on Growth Performance, Peripheral Blood Cell Profile, and Gut Microbiota of Nursery Pigs
- Isolated Rearing at Lactation Increases Gut Microbial Diversity and Post-weaning Performance in Pigs
Showing 5 of 30 shared publications
Cynthia Maxwell
University of Arkansas at Fayetteville (US)
23 shared publications
- 219 Effect of yeast cell wall (YCW) inclusion rate on growth performance in nursery pigs
- A cooperative study assessing the effects of a second iron injection administered before weaning on growth performance, hematological status, and tissue mineral concentrations of nursery pigs*
- 179 Effect of topsoil exposure during lactation on subsequent performance and abundance of innate and adaptive immune cells in pigs
- 254 Effects of supplementation with a protease, carbohydrases, and phytase in reduced-nutrient diets fed from weaning to market on growth performance, nutrients digestibility, intestinal morphology, and hematological characteristics
- 137 Effects of a Corn-Expressed Phytase on Growth Performance and Bone Ash of Nursery Pigs.
Showing 5 of 23 shared publications
Jiangchao Zhao
Key Laboratory of Guangdong Province
20 shared publications
In database
- Longitudinal investigation of the swine gut microbiome from birth to market reveals stage and growth performance associated bacteria
- Weaning Induced Gut Dysfunction and Nutritional Interventions in Nursery Pigs: A Partial Review
- Dietary Organic Acids Modulate Gut Microbiota and Improve Growth Performance of Nursery Pigs
- Comprehensive Cultivation of the Swine Gut Microbiome Reveals High Bacterial Diversity and Guides Bacterial Isolation in Pigs
- ZnO Modulates Swine Gut Microbiota and Improves Growth Performance of Nursery Pigs When Combined with Peptide Cocktail
Showing 5 of 20 shared publications
J. J. Chewning
Marymount University (US)
10 shared publications
- Influence of a whole yeast product (Pichia guilliermondii) fed throughout gestation and lactation on performance and immune parameters of the sow and litter
- 254 Effects of supplementation with a protease, carbohydrases, and phytase in reduced-nutrient diets fed from weaning to market on growth performance, nutrients digestibility, intestinal morphology, and hematological characteristics
- 137 Effects of a Corn-Expressed Phytase on Growth Performance and Bone Ash of Nursery Pigs.
- 277 The Effect of Corn-Expressed Phytase Supplementation in Adequate or Low Levels of Phosphorous and Calcium Diets on Growth Performance and Bone Ash of Nursery Pigs.
- Impact of Pichia guilliermondii on sow, litter, and weaned pig immune performance
Showing 5 of 10 shared publications
Xiaoyuan Wei
University of Arkansas at Fayetteville (US)
9 shared publications
- Longitudinal investigation of the swine gut microbiome from birth to market reveals stage and growth performance associated bacteria
- Weaning Induced Gut Dysfunction and Nutritional Interventions in Nursery Pigs: A Partial Review
- Dietary Organic Acids Modulate Gut Microbiota and Improve Growth Performance of Nursery Pigs
- Comprehensive Cultivation of the Swine Gut Microbiome Reveals High Bacterial Diversity and Guides Bacterial Isolation in Pigs
- ZnO Modulates Swine Gut Microbiota and Improves Growth Performance of Nursery Pigs When Combined with Peptide Cocktail
Showing 5 of 9 shared publications
E. B. Kegley
United States Department of Agriculture
7 shared publications
In database
- Isolated Rearing at Lactation Increases Gut Microbial Diversity and Post-weaning Performance in Pigs
- 179 Effect of topsoil exposure during lactation on subsequent performance and abundance of innate and adaptive immune cells in pigs
- 259 Effect of rearing strategies during lactation on growth performance and the population of innate and adaptive immune cells in pigs from pre-weaning to market
- 360 Effect of Simulated Outdoor Rearing on Growth Performance, Health, Blood Minerals, and Complete Blood Cell Count in Wean-to-Finish Pigs.
- PSIV-27 Peripheral complete blood cell count results in pigs are impacted by gender, sow parity, and farrowing season
Showing 5 of 7 shared publications
Hansol Kim
University of Arkansas at Fayetteville (US)
6 shared publications
- 179 Effect of topsoil exposure during lactation on subsequent performance and abundance of innate and adaptive immune cells in pigs
- 258 Effects of supplementation with Aspergillus oryzae derived phytase (Ronozyme® HiPhos) and fiber degrading enzymes (Victusô® Swine Starter) on growth performance, intestinal morphology, leukocyte differential, and nutrient digestibility in nursery pigs
- 259 Effect of rearing strategies during lactation on growth performance and the population of innate and adaptive immune cells in pigs from pre-weaning to market
- 286 Effect of Saccharomyces cerevisiae fermentation product supplementation in late gestation and lactation on sow and litter performance, milk components, and fecal Clostridium perfringens
- 194 Supplementation of feed grade essential and non-essential amino acids to control levels in pigs fed reduced crude protein (RCP) diets meeting the SID His:Lys ratio requirement maintained growth performance and carcass composition in growing/finishing swine
Showing 5 of 6 shared publications
M. A. Sales
University of Arkansas at Fayetteville (US)
6 shared publications
- 179 Effect of topsoil exposure during lactation on subsequent performance and abundance of innate and adaptive immune cells in pigs
- 259 Effect of rearing strategies during lactation on growth performance and the population of innate and adaptive immune cells in pigs from pre-weaning to market
- 178 Evaluation of porcine IPEC-J2 cell line immune tesponse to Escherichia coli (0111:B4) lLipopolysaccharide
- 702 Differential gene expression in peripheral mononuclear cells of pigs exposed to topsoil in early life
- 701 Decreased ileal permeability in piglets at weaning following exposure to irradiated topsoil
Showing 5 of 6 shared publications
Jon R Bergstrom
DSM (Netherlands) (NL)
6 shared publications
- Dietary Organic Acids Modulate Gut Microbiota and Improve Growth Performance of Nursery Pigs
- 254 Effects of supplementation with a protease, carbohydrases, and phytase in reduced-nutrient diets fed from weaning to market on growth performance, nutrients digestibility, intestinal morphology, and hematological characteristics
- 258 Effects of supplementation with Aspergillus oryzae derived phytase (Ronozyme® HiPhos) and fiber degrading enzymes (Victusô® Swine Starter) on growth performance, intestinal morphology, leukocyte differential, and nutrient digestibility in nursery pigs
- 273 Longitudinal Investigation of Nutrient Intervention During Gilts Development on Sow Reproductive Performance and Longevity
- PSIV-1 Nutrient Intervention During Gilt Development Leads to Effects on Progeny Growth Responses
Showing 5 of 6 shared publications
C.J. Maxwell
University of Arkansas at Fayetteville (US)
6 shared publications
- Early exposure to agricultural soil accelerates the maturation of the early-life pig gut microbiota
- Dietary Organic Acids Modulate Gut Microbiota and Improve Growth Performance of Nursery Pigs
- ZnO Modulates Swine Gut Microbiota and Improves Growth Performance of Nursery Pigs When Combined with Peptide Cocktail
- PSIII-21 Optimum SID Threonine to Lysine Ratio in Nursery Pigs
- Effects of Early-Life Exposure to Topsoil on the Muscle Fiber Characteristics and Gene Expression of Weaned Piglets
Showing 5 of 6 shared publications
Casey L Bradley
6 shared publications
- Dietary Organic Acids Modulate Gut Microbiota and Improve Growth Performance of Nursery Pigs
- 144 Effect of sodium butyrate (SB) on growth performance and complete blood cell count in nursery pigs: Two facility study
- 174 The effect of a microbial Muramidase on peptidoglycan content in the gut of swine using in-vitro and in-vivo measures
- PSIII-12 The effect of sodium butyrate and benzoic acid on nutrient digestibility and fecal volatile fatty acid concentrations in nursery pigs
- PSV-14 The Efficacy of Feeding a Bioactive Peptide in Comparison to Narasin in Growing Pigs in a Commercial System on Growth Performance and Efficiency
Showing 5 of 6 shared publications
J. K. Apple
University of Arkansas at Fayetteville (US)
5 shared publications
- Longitudinal investigation of the swine gut microbiome from birth to market reveals stage and growth performance associated bacteria
- 194 Supplementation of feed grade essential and non-essential amino acids to control levels in pigs fed reduced crude protein (RCP) diets meeting the SID His:Lys ratio requirement maintained growth performance and carcass composition in growing/finishing swine
- Effects of crystalline amino acid supplementation of reduced crude protein (RCP) diet on net energy basis on Longissimus muscle (LM) quality of growing-finishing swine
- 198 Effects of aggressive feed-grade amino acid supplementation in reduced CP diets formulated on ME or NE basis on growth performance of nursery pigs
- PSIV-4 The effect of peptide product and ZnO on growth performance in nursery pigs fed different levels of crude protein diets.
Benjamin Bass
5 shared publications
- Influence of a whole yeast product (Pichia guilliermondii) fed throughout gestation and lactation on performance and immune parameters of the sow and litter
- Impact of Pichia guilliermondii on sow, litter, and weaned pig immune performance
- 286 Effect of Saccharomyces cerevisiae fermentation product supplementation in late gestation and lactation on sow and litter performance, milk components, and fecal Clostridium perfringens
- PSVI-18 Establishing ideal inclusion rate of fermented soybean meal (FSBM) in nursery rations
- PSII-19 Effect of a Sensory Additive on Sow Feed Intake During Lactation
Xianfeng Wang
University of Arkansas at Fayetteville (US)
5 shared publications
- 219 Effect of yeast cell wall (YCW) inclusion rate on growth performance in nursery pigs
- 179 Effect of topsoil exposure during lactation on subsequent performance and abundance of innate and adaptive immune cells in pigs
- 259 Effect of rearing strategies during lactation on growth performance and the population of innate and adaptive immune cells in pigs from pre-weaning to market
- 286 Effect of Saccharomyces cerevisiae fermentation product supplementation in late gestation and lactation on sow and litter performance, milk components, and fecal Clostridium perfringens
- 178 Evaluation of porcine IPEC-J2 cell line immune tesponse to Escherichia coli (0111:B4) lLipopolysaccharide
Xiao‐Fan Wang
University of Arkansas at Fayetteville (US)
5 shared publications
- Longitudinal investigation of the swine gut microbiome from birth to market reveals stage and growth performance associated bacteria
- Comprehensive Cultivation of the Swine Gut Microbiome Reveals High Bacterial Diversity and Guides Bacterial Isolation in Pigs
- Effect of Lactylate and Bacillus subtilis on Growth Performance, Peripheral Blood Cell Profile, and Gut Microbiota of Nursery Pigs
- Isolated Rearing at Lactation Increases Gut Microbial Diversity and Post-weaning Performance in Pigs
- Donor age and body weight determine the effects of fecal microbiota transplantation on growth performance, and fecal microbiota development in recipient pigs
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