V. V. Lyzogubov
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Also affiliated: University of Arkansas Medical Center (2007–2010)
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Biography and Research Information
OverviewAI-generated summary
V. V. Lyzogubov's research has focused on the molecular mechanisms of angiogenesis, particularly in the context of ocular diseases. His work has investigated the role of adiponectin, a peptide hormone, in inhibiting endothelial cell proliferation and vessel growth. Studies have explored adiponectin's regulation of vascular endothelial growth factor (VEGF) and its receptors in models of choroidal neovascularization (CNV). Further research has examined the relationship between complement activation and CNV, including the correlation between complement factor H and the membrane attack complex in mouse models. Lyzogubov has also contributed to the characterization of antibodies against adaptor/scaffold proteins like Ruk/CIN85/SETA. His publications include work on P70S6 kinase isoforms in cell lines and breast tumors.
Metrics
- h-index: 1
- Publications: 15
- Citations: 7
Selected Publications
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Relationship Between Complement Activation and Choroidal Neovascularization in Type II Diabetes (2010)
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Correlation Between Complement Factor H and Membrane Attack Complex in Mouse Model of CNV (2009)Investigative Ophthalmology & Visual Science OpenAlex
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Suppression of Complement Factor H Increases Deposition of Membrane Attack Complex and Vessel Growth in Mouse Model of CNV (2009)Investigative Ophthalmology & Visual Science OpenAlex
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Increased Severity of Choroidal Neovascularization in Laser Treated Rats After Alcohol and Nicotine Feeding (2008)Investigative Ophthalmology & Visual Science OpenAlex
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Adiponectin Petide Regulates VEGF and Its Receptors 1 and 2 Expression in Rat Model of CNV (2008)Investigative Ophthalmology & Visual Science OpenAlex
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Adiponectin Peptide Inhibits Proliferation of Endothelial Cells and Inhibits Vessel Growth in Mouse Model of Laser Induced CNV (2008)
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Localization of Adiponectin and Its Receptors in Mouse Model of Choroidal Neovascularization (2007)Investigative Ophthalmology & Visual Science OpenAlex
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