William Mustain

Sourced from institutional research profiles (UAMS TRI or ARA).

Associate Professor

UAMS

Surgery, College of Medicine

18 h-index 77 pubs 1,401 cited

Research Areas

Biomedical Subjects

Links

ORCID Lab Website Research Group UAMS TRI Profile

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OverviewAI-generated summary

Dr. W. Conan Mustain's research focuses on the molecular mechanisms underlying colorectal cancer progression and metastasis. His work investigates the role of fatty acid synthase (FASN) in CD44-associated signaling, demonstrating its potential to reduce metastasis. He has also explored how cancer cell-associated FASN activates endothelial cells, promoting angiogenesis in colorectal cancer.

Dr. Mustain's research extends to the delivery of therapeutic agents to colorectal cancer metastases. He has published on the use of RNA nanoparticles for systemic delivery to these sites. His broader clinical interests include the treatment of various colon and rectal diseases, such as colorectal cancer, inflammatory bowel disease, diverticulitis, fecal incontinence, and rectal prolapse.

With an h-index of 18 and over 1,400 citations across 77 publications, Dr. Mustain's scholarly contributions are notable. He leads a research group and maintains an active lab website, indicating ongoing research activities. His collaborations include work with researchers at the University of Arkansas for Medical Sciences.

Research Overview

Dr. W. Conan Mustain is a native of Jackson, MS. He attended Florida State University, where he was inducted into the Phi Beta Kappa society and graduated Magna Cum Laude. After earning his medical degree at the University of Mississippi School of Medicine, Dr. Mustain completed his internship and residency in general surgery at the University of Kentucky Medical Center in Lexington, where he served as Administrative Chief Resident. During residency he spent 2 years as a surgical research fellow in the University of Kentucky Markey Cancer Center conducting basic science research in colorectal cancer and inflammatory bowel disease. After residency he completed fellowship training in colon and rectal surgery at University Hospitals Case Medical Center-Case Western Reserve University in Cleveland, OH. Dr. Mustain is an assistant professor in the Department of Surgery. Dr. Mustain is board-certified in general surgery and board-eligible in colon and rectal surgery. He specializes in the treatment of diseases of the colon and rectum including colorectal cancer, inflammatory bowel disease, diverticulitis, fecal incontinence, rectal prolapse, and benign anorectal conditions. His special interests include laparoscopic colon and rectal surgery, complex anorectal disease, and sphincter-preserving surgery for rectal cancer. He is a member of the American Society of Colon and Rectal Surgeons, the American College of Surgeons, and the Alpha Omega Alpha Honor Medical Society. He has won numerous awards for excellence in teaching and research and has presented his work at several national and regional meetings. Dr. Mustain lives in the Hillcrest neighborhood in Little Rock with his wife and two young boys. He sees patients in the Winthrop P. Rockefeller Cancer Institute

Metrics

h-index: 18
Publications: 77
Citations: 1,401

Selected Publications

Improvement in Functional Outcomes Following Ileal Pouch-Anal Anastomosis: Results from the United States Ileal Pouch-Anal Anastomosis Study (2025)

Diseases of the Colon & Rectum 4 citations DOI OpenAlex
Surgical Residents’ Perception of Multi-Specialty Learning (2022)

Journal of surgical education 1 citation DOI OpenAlex
The Impact of Transversus Abdominis Plane Block Within an Enhanced Recovery After Surgery Protocol on Length of Stay (2020)

Diseases of the Colon & Rectum 6 citations DOI OpenAlex
Cost Impact of Implementing an Enhanced Recovery after Surgery Protocol: An Institutional Review (2018)

Journal of the American College of Surgeons DOI OpenAlex
Multiport Laparoscopic Abdominoperineal Resection (2018)

DOI OpenAlex
Fluorescein as a topical fluorescent contrast agent for quantitative microendoscopic inspection of colorectal epithelium (2017)

Biomedical Optics Express 16 citations DOI OpenAlex
Quality Improvement: Enhanced Recovery Pathways for Open Surgery (2017)

Difficult decisions in surgery: an evidence-based approach DOI OpenAlex
Functional Disorders: Rectocele (2016)

Clinics in Colon and Rectal Surgery 55 citations DOI OpenAlex