Timothy J. Muldoon

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

Federal Grant PI

Associate Professor

University of Arkansas primary UA Little Rock

Also affiliated: University of North Carolina at Chapel Hill (2024); North Carolina State University (2024); University of Utah (2024); In-Q-Tel (2016); Optica (2012); Rice University (2007–2012); Columbia University (2012); University of California, Davis (2024); University of Toledo (2024)

Faculty Researcher

17 h-index 95 pubs 1,378 cited

Research Areas

Biomedical Subjects

Links

ORCID Lab Website

OverviewAI-generated summary

Timothy J. Muldoon's research focuses on the intersection of biomedical optics, imaging techniques, and cancer biology. He investigates how advanced imaging methods can be used to understand tumor physiology and guide therapeutic strategies. His work includes developing and applying techniques such as diffuse reflectance spectroscopy and optical imaging to analyze metabolic cofactors and perfusion markers in various cancer models, including murine colon carcinoma.

Dr. Muldoon's research also explores the role of specific cellular components, such as macrophages and cytokines, in modulating tumor response to treatment. He has published studies examining macrophage-targeted immunotherapies and their impact on drug sensitivity, as well as investigating the physiological and therapeutic roles of CD47 in macrophage function and cancer. His work further extends to statistical modeling for longitudinal biomedical data and the development of multicellular tumor spheroids with spatial metabolic characterization.

With an h-index of 17 and over 1,300 citations, Dr. Muldoon has a significant publication record. He has served as PI on an NSF-funded REU Site grant focused on training students in emerging biomedical optics and imaging approaches. His collaborations include work with researchers at the University of Arkansas at Fayetteville, such as Shelby N. Bess, Mostafa Elsaadany, Matthew J. Igoe, and Christopher E. Nelson.

Metrics

h-index: 17
Publications: 95
Citations: 1,378

Selected Publications

Differential impact of cancer- and chemotherapy-induced cachexia: a comparative analysis in a preclinical model of colorectal cancer by biological sex (2026)

American Journal of Physiology-Endocrinology and Metabolism DOI OpenAlex
Metabolic Imaging and Characterization of Multicomponent Spheroid Models in Vitro. (2025)

DOI OpenAlex
BOARD # 307: University of Arkansas Biomedical Engineering REU Site: Training in Emerging Biomedical Optics and Imaging Approaches (2025)

DOI OpenAlex
BOARD # 16: Equipping Biomedical Engineering Students with User-Centered Design Skills: Insights from a Clinical Immersion Course (2025)

DOI OpenAlex
Advancing Equity in Biomedical Engineering Education: Insights from Clinical Observations and Needs-Finding Courses (2025)

DOI OpenAlex
A dual-fluorescence assay for gene delivery vehicle screening in macrophages with an inflammation-inducible reporter construct (2025)

BMC Methods DOI OpenAlex
Quantifying treatment response to a macrophage-targeted therapy in combination with immune checkpoint inhibitors after exposure to conventional chemotherapy (2025)

Frontiers in Immunology DOI OpenAlex
The Physiological and Therapeutic Role of CD47 in Macrophage Function and Cancer (2024)

Immunological Investigations 10 citations DOI OpenAlex
Development of an Innovation Corps-Modelled Bioengineering Course to Promote Entrepreneurial Engagement Among Undergraduate Students (2024)

DOI OpenAlex
Toward Equity and Inclusivity in Engineering Classrooms: Understanding Students' Disparities in Response to Clinical Observations and Needs-Finding Course Development (2024)

DOI OpenAlex
Assessment and Impact of a Clinical Observations and Needs Finding Course on Biomedical Engineering Education Outcomes (2024)

DOI OpenAlex
Scaffold-free development of multicellular tumor spheroids with spatial characterization of structure and metabolic radial profiles (2024)

In vitro models 13 citations DOI OpenAlex
Abstract 5549: Multicellular spheroid structural and metabolic characterization through radial line profiling (2024)

Cancer Research DOI OpenAlex
Board 107: Work in Progress: Development of an Innovation Corps-Modeled Bioengineering Course to Promote Entrepreneurial Engagement among Undergraduate Students. (2024)

DOI OpenAlex
Board 12: Work in progress: Assessment and impact of a Clinical Observations and Needs Finding service-learning course on Biomedical Engineering outcomes (2024)

DOI OpenAlex