Match tier
Confirmed
Presence
Current · Arkansas
Last published
2026
Sources
OpenAlex · ORCID
Refreshed
2026-10-05
S
Sangeeta Khare
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
High Impact
Research Microbiologist
Also affiliated: Texas A&M Health Science Center (2011); Lawrence Livermore National Laboratory (2005); United States Food and Drug Administration (2010–2026); Fred Hutch Cancer Center (2010); Instituto de Productos Lácteos de Asturias (2023); All India Institute of Medical Sciences (1993–1997); Texas A&M University (1998–2017)
28 h-index
105 pubs
8,790 cited
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Sangeeta Khare is a research microbiologist at the National Center for Toxicological Research. Her work focuses on the interactions between ingested substances, the gastrointestinal microbiome, and host immune responses. Khare has investigated the effects of silver nanoparticles and nanocellulose on the intestinal microbiota and gut-associated immune responses in rat models. She has also studied the role of bacterial effector proteins in host-specific chemokine profiles during Salmonella enterica serotype Typhimurium infections.
Her research has explored the detection of Mycobacterium avium subsp. paratuberculosis in bovine milk and feces using PCR-based methods. Khare has also contributed to understanding the invasion mechanisms of Salmonella enterica serotype Typhimurium in epithelial cells and the expression of fimbrial operons. Her work involves both in vivo and in vitro models, including human gut epithelium models, to assess the impact of nanoparticles on intestinal permeability. Khare's research is supported by significant publication and citation metrics, with an h-index of 28 and over 8,800 citations across 119 publications.
Metrics
- h-index: 28
- Publications: 105
- Citations: 8,790
Positions
-
Postdoctoral FellowUniversity of Saskatchewan Microbiology ORCID
-
Texas A&M University publications 1998–2017Veterinary Pathobiology ORCID
-
Research Microbiologist publications 2010–2026National Center for Toxicological Research Microbiology ORCID
Selected Publications
-
Tri-Combination Antiretroviral Therapy Induces Dose- and Time-Dependent Disruption of Intestinal Epithelial Barrier Function and Repair Responses in Human T84 Cells (2026)
-
Gestational and lactational exposure to HIV tri-combination therapy induces sex- and dose-dependent changes in inflammatory cytokine profiles, intestinal permeability, and villi morphology in adult rat offspring (2026)
-
Silver nanoparticles at sub-cytotoxic levels increase enteric pathogen invasion by compromising intestinal epithelial barrier integrity (2026)
-
Zileuton nanocrystals alter intestinal phase I/II metabolic enzymes and epithelial permeability in a sex-dependent manner (2025)
-
Gestational exposure to HIV drugs alters intestinal mucosa-associated microbial diversity in adult rat offspring (2025)
-
Potential link of high fat diet and mRNA expression of Alzheimer's disease-related genes in the enteric mucosa of a rat model of Alzheimer's disease (2025)
-
Effect of in utero and lactational exposure to antiretroviral therapy on the gut microbial composition and metabolic function in aged rat offspring (2025)
-
Strategies to Enhance Nanocrystal Formulations for Overcoming Physiological Barriers Across Diverse Routes of Administration (2025)
-
Relevance of gut microbiome research in food safety assessment (2024)
-
Evaluation of gender differences in the pharmacokinetics of oral zileuton nanocrystalline formulation using a rat model (2024)
-
Early Developmental Exposure to Triclosan Impacts Fecal Microbial Populations, IgA and Functional Activities of the Rat Microbiome (2024)
-
Evaluation of mucosal immune profile associated with Zileuton nanocrystal-formulated BCS-II drug upon oral administration in Sprague Dawley rats (2023)
-
Relevance of gut microbiome research in food safety assessment (2023)
-
Route of Arsenic Exposure Differentially Impacts the Expression of Genes Involved in Gut-Mucosa-Associated Immune Responses and Gastrointestinal Permeability (2023)
-
Structural analysis of VirD4 a type IV ATPase encoded by transmissible plasmids of Salmonella enterica isolated from poultry products (2022)
Collaboration Network
Top Collaborators
Kuppan Gokulan
National Center for Toxicological Research
50 shared publications
In database
- Size and dose dependent effects of silver nanoparticle exposure on intestinal permeability in an in vitro model of the human gut epithelium
- Effects of ingested nanocellulose on intestinal microbiota and homeostasis in Wistar Han rats
- Dose and Size-Dependent Antiviral Effects of Silver Nanoparticles on Feline Calicivirus, a Human Norovirus Surrogate
- Exposure to Arsenite in CD-1 Mice during Juvenile and Adult Stages: Effects on Intestinal Microbiota and Gut-Associated Immune Status
- Impact of Plasmids, Including Those EncodingVirB4/D4 Type IV Secretion Systems, on Salmonella enterica serovar Heidelberg Virulence in Macrophages and Epithelial Cells
Showing 5 of 50 shared publications
Carl E. Cerniglia
National Center for Toxicological Research
17 shared publications
In database
- Size and dose dependent effects of silver nanoparticle exposure on intestinal permeability in an in vitro model of the human gut epithelium
- Exposure to Arsenite in CD-1 Mice during Juvenile and Adult Stages: Effects on Intestinal Microbiota and Gut-Associated Immune Status
- METABOLIC PATHWAYS | Production of Secondary Metabolites of Bacteria
- Effects of residual levels of tetracycline on the barrier functions of human intestinal epithelial cells
- An in vitro study to assess the impact of tetracycline on the human intestinal microbiome
Showing 5 of 17 shared publications
Katherine M. Williams
National Center for Toxicological Research (US)
17 shared publications
- Size and dose dependent effects of silver nanoparticle exposure on intestinal permeability in an in vitro model of the human gut epithelium
- Dose and Size-Dependent Antiviral Effects of Silver Nanoparticles on Feline Calicivirus, a Human Norovirus Surrogate
- Graphene and carbon nanotubes activate different cell surface receptors on macrophages before and after deactivation of endotoxins
- Assessment of silver release and biocidal capacity from silver nanocomposite food packaging materials
- Human Intestinal Tissue Explant Exposure to Silver Nanoparticles Reveals Sex Dependent Alterations in Inflammatory Responses and Epithelial Cell Permeability
Showing 5 of 17 shared publications
Steven L. Foley
National Center for Toxicological Research
6 shared publications
In database
- Impact of Plasmids, Including Those EncodingVirB4/D4 Type IV Secretion Systems, on Salmonella enterica serovar Heidelberg Virulence in Macrophages and Epithelial Cells
- Evaluation of Virulence and Antimicrobial Resistance in Salmonella enterica Serovar Enteritidis Isolates from Humans and Chicken- and Egg-Associated Sources
- The Gut Microbiome and Xenobiotics: Identifying Knowledge Gaps
- Structure and Inhibitor Specificity of L,D-Transpeptidase (LdtMt2) from Mycobacterium tuberculosis and Antibiotic Resistance: Calcium Binding Promotes Dimer Formation
- Transmissible Plasmid Containing Salmonella enterica Heidelberg Isolates Modulate Cytokine Production During Early Stage of Interaction with Intestinal Epithelial Cells
Showing 5 of 6 shared publications
Mohamed H. Lahiani
National Center for Toxicological Research
6 shared publications
In database
- Graphene and carbon nanotubes activate different cell surface receptors on macrophages before and after deactivation of endotoxins
- The impact of tomato fruits containing multi-walled carbon nanotube residues on human intestinal epithelial cell barrier function and intestinal microbiome composition
- Impact of Pristine Graphene on Intestinal Microbiota Assessed Using a Bioreactor-Rotary Cell Culture System
- Differential Toxicological Outcome of Corn Oil Exposure in Rats and Mice as Assessed by Microbial Composition, Epithelial Permeability, and Ileal Mucosa-Associated Immune Status
- Ex Vivo Human Colon Tissue Exposure to Pristine Graphene Activates Genes Involved in the Binding, Adhesion and Proliferation of Epithelial Cells
Showing 5 of 6 shared publications
Vicki Sutherland
National Institute of Environmental Health Sciences (US)
6 shared publications
- The Gut Microbiome and Xenobiotics: Identifying Knowledge Gaps
- Differential Toxicological Outcome of Corn Oil Exposure in Rats and Mice as Assessed by Microbial Composition, Epithelial Permeability, and Ileal Mucosa-Associated Immune Status
- Early Developmental Exposure to Triclosan Impacts Fecal Microbial Populations, IgA and Functional Activities of the Rat Microbiome
- Effect of in utero and lactational exposure to antiretroviral therapy on the gut microbial composition and metabolic function in aged rat offspring
- Gestational exposure to HIV drugs alters intestinal mucosa-associated microbial diversity in adult rat offspring
Showing 5 of 6 shared publications
Yaswanthi Yanamadala
National Center for Toxicological Research
6 shared publications
In database
- Strategies to Enhance Nanocrystal Formulations for Overcoming Physiological Barriers Across Diverse Routes of Administration
- Effect of in utero and lactational exposure to antiretroviral therapy on the gut microbial composition and metabolic function in aged rat offspring
- Gestational exposure to HIV drugs alters intestinal mucosa-associated microbial diversity in adult rat offspring
- Zileuton nanocrystals alter intestinal phase I/II metabolic enzymes and epithelial permeability in a sex-dependent manner
- Gestational and lactational exposure to HIV tri-combination therapy induces sex- and dose-dependent changes in inflammatory cytokine profiles, intestinal permeability, and villi morphology in adult rat offspring
Showing 5 of 6 shared publications
Silvia A. Piñeiro
Center for Veterinary Medicine (US)
5 shared publications
- Effects of residual levels of tetracycline on the barrier functions of human intestinal epithelial cells
- An in vitro study to assess the impact of tetracycline on the human intestinal microbiome
- Impact of Chronic Tetracycline Exposure on Human Intestinal Microbiota in a Continuous Flow Bioreactor Model
- In vitro test systems to determine tetracycline residue binding to human feces
- Effects of Acute and Chronic Exposure to Residual Level Erythromycin on Human Intestinal Epithelium Cell Permeability and Cytotoxicity
Helen Cunny
National Institute of Environmental Health Sciences (US)
4 shared publications
- Early Developmental Exposure to Triclosan Impacts Fecal Microbial Populations, IgA and Functional Activities of the Rat Microbiome
- Effect of in utero and lactational exposure to antiretroviral therapy on the gut microbial composition and metabolic function in aged rat offspring
- Gestational exposure to HIV drugs alters intestinal mucosa-associated microbial diversity in adult rat offspring
- Gestational and lactational exposure to HIV tri-combination therapy induces sex- and dose-dependent changes in inflammatory cytokine profiles, intestinal permeability, and villi morphology in adult rat offspring
Chandra Mohan Reddy Muthumula
National Center for Toxicological Research
4 shared publications
In database
- Strategies to Enhance Nanocrystal Formulations for Overcoming Physiological Barriers Across Diverse Routes of Administration
- Effect of in utero and lactational exposure to antiretroviral therapy on the gut microbial composition and metabolic function in aged rat offspring
- Gestational exposure to HIV drugs alters intestinal mucosa-associated microbial diversity in adult rat offspring
- Evaluation of gender differences in the pharmacokinetics of oral zileuton nanocrystalline formulation using a rat model
Kumari Karn
National Center for Toxicological Research
4 shared publications
In database
- Effect of in utero and lactational exposure to antiretroviral therapy on the gut microbial composition and metabolic function in aged rat offspring
- Potential link of high fat diet and mRNA expression of Alzheimer's disease-related genes in the enteric mucosa of a rat model of Alzheimer's disease
- Gestational exposure to HIV drugs alters intestinal mucosa-associated microbial diversity in adult rat offspring
- Gestational and lactational exposure to HIV tri-combination therapy induces sex- and dose-dependent changes in inflammatory cytokine profiles, intestinal permeability, and villi morphology in adult rat offspring
Ashraf A. Khan
National Center for Toxicological Research
3 shared publications
In database
- Molecular Characterization of Fluoroquinolone-Resistant Aeromonas spp. Isolated from Imported Shrimp
- Cytotoxic Mechanism of Cytolethal Distending Toxin in Nontyphoidal Salmonella Serovar ( Salmonella Javiana) During Macrophage Infection
- Mechanisms of Quinolone Resistance in Vibrio parahemolyticus strains Isolated from Imported Shrimp
Aschalew Z. Bekele
National Center for Toxicological Research (US)
3 shared publications
- Dose and Size-Dependent Antiviral Effects of Silver Nanoparticles on Feline Calicivirus, a Human Norovirus Surrogate
- Responses of intestinal virome to silver nanoparticles: safety assessment by classical virology, whole-genome sequencing and bioinformatics approaches
- Human Intestinal Microbial Biofilm and its Correlation with Intestinal Mucin Secretion
Ji Young Jung
National Center for Toxicological Research (US)
3 shared publications
- An in vitro study to assess the impact of tetracycline on the human intestinal microbiome
- Impact of Chronic Tetracycline Exposure on Human Intestinal Microbiota in a Continuous Flow Bioreactor Model
- In vitro test systems to determine tetracycline residue binding to human feces
Youngbeom Ahn
National Center for Toxicological Research
3 shared publications
In database
- An in vitro study to assess the impact of tetracycline on the human intestinal microbiome
- Impact of Chronic Tetracycline Exposure on Human Intestinal Microbiota in a Continuous Flow Bioreactor Model
- In vitro test systems to determine tetracycline residue binding to human feces
Similar Researchers
Based on overlapping research topics
Kuppan Gokulan
National Center for Toxicological Research
Pharmacological Effects and Toxicity Studies
Gut microbiota and health
Host-Pathogen Interactions
Monica Sadaka
University of Arkansas at Little Rock
Pharmacological Effects and Toxicity Studies
Host-Pathogen Interactions
Microbial infections and disease research
Mei G. Lei
University of Arkansas for Medical Sciences
Host-Pathogen Interactions
Immune Response and Inflammation
Microbial infections and disease research
Elysia A. Masters
National Center for Toxicological Research
Pharmacological Effects and Toxicity Studies
Host-Pathogen Interactions
Immune Response and Inflammation
Mohit Bansal
University of Arkansas at Fayetteville
Gut microbiota and health
Host-Pathogen Interactions
Immune Response and Inflammation
Jerry W. Simecka
University of Arkansas for Medical Sciences
Host-Pathogen Interactions
Immune Response and Inflammation
Microbial infections and disease research