Biography and Research Information
OverviewAI-generated summary
Pravin Parajuli's research focuses on understanding the molecular mechanisms underlying various biological processes and disease states. His work has explored the conformational changes of the SARS-CoV-2 spike protein's receptor binding domain and the prediction of B-cell antigenic epitopes. Parajuli has also investigated preclinical models to assess the impact of arsenite exposure on intestinal epithelial cells, examining changes in permeability and cytotoxicity. Additionally, his research has involved the development of peptidomimetic analogs of sunflower trypsin inhibitors to target protein-protein interactions for immunomodulation, specifically suppressing rheumatoid arthritis progression in an experimental model. Parajuli has a publication record of eight works, with 165 citations, and an h-index of 4. He has collaborated with researchers including Sangeeta Khare and Kuppan Gokulan from the National Center for Toxicological Research.
Metrics
- h-index: 4
- Publications: 8
- Citations: 167
Selected Publications
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Preclinical In Vitro Model to Assess the Changes in Permeability and Cytotoxicity of Polarized Intestinal Epithelial Cells during Exposure Mimicking Oral or Intravenous Routes: An Example of Arsenite Exposure (2022)
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Conformational Changes of the Receptor Binding Domain of SARS-CoV-2 Spike Protein and Prediction of a B-Cell Antigenic Epitope Using Structural Data (2021)
Collaboration Network
Top Collaborators
Sangeeta Khare
United States Food and Drug Administration
2 shared publications
In database
- Conformational Changes of the Receptor Binding Domain of SARS-CoV-2 Spike Protein and Prediction of a B-Cell Antigenic Epitope Using Structural Data
- Preclinical In Vitro Model to Assess the Changes in Permeability and Cytotoxicity of Polarized Intestinal Epithelial Cells during Exposure Mimicking Oral or Intravenous Routes: An Example of Arsenite Exposure
Kuppan Gokulan
United States Food and Drug Administration
2 shared publications
In database
- Conformational Changes of the Receptor Binding Domain of SARS-CoV-2 Spike Protein and Prediction of a B-Cell Antigenic Epitope Using Structural Data
- Preclinical In Vitro Model to Assess the Changes in Permeability and Cytotoxicity of Polarized Intestinal Epithelial Cells during Exposure Mimicking Oral or Intravenous Routes: An Example of Arsenite Exposure
Tonking Bastola
Wonkwang University (KR)
2 shared publications
- Eriolobus indica (Wall.) Decne
- Contributors
Marli S.P. Azevedo
United States Food and Drug Administration
1 shared publication
In database
- Conformational Changes of the Receptor Binding Domain of SARS-CoV-2 Spike Protein and Prediction of a B-Cell Antigenic Epitope Using Structural Data
Achyut Dahal
University of Louisiana at Monroe (US)
1 shared publication
- Targeting protein–protein interaction for immunomodulation: A sunflower trypsin inhibitor analog peptidomimetic suppresses RA progression in CIA model
Sitanshu S. Singh
University of Louisiana at Monroe (US)
1 shared publication
- Targeting protein–protein interaction for immunomodulation: A sunflower trypsin inhibitor analog peptidomimetic suppresses RA progression in CIA model
Leeza Shrestha
University of Louisiana at Monroe (US)
1 shared publication
- Targeting protein–protein interaction for immunomodulation: A sunflower trypsin inhibitor analog peptidomimetic suppresses RA progression in CIA model
Jafrin Jobayer Sonju
University of Louisiana at Monroe (US)
1 shared publication
- Targeting protein–protein interaction for immunomodulation: A sunflower trypsin inhibitor analog peptidomimetic suppresses RA progression in CIA model
Prajesh Shrestha
University of Louisiana at Monroe (US)
1 shared publication
- Targeting protein–protein interaction for immunomodulation: A sunflower trypsin inhibitor analog peptidomimetic suppresses RA progression in CIA model
Ioulia Chatzistamou
University of South Carolina (US)
1 shared publication
- Targeting protein–protein interaction for immunomodulation: A sunflower trypsin inhibitor analog peptidomimetic suppresses RA progression in CIA model
Seetharama D. Jois
University of Louisiana at Monroe (US)
1 shared publication
- Targeting protein–protein interaction for immunomodulation: A sunflower trypsin inhibitor analog peptidomimetic suppresses RA progression in CIA model
Santosh Lamichhane
Louisiana State University (US)
1 shared publication
- Eriolobus indica (Wall.) Decne
Grinsun Sharma
Wonkwang University (KR)
1 shared publication
- Eriolobus indica (Wall.) Decne
Prakash Poudel
Pokhara University (NP)
1 shared publication
- Eriolobus indica (Wall.) Decne
Mahendra Adhikari
Heinrich Heine University Düsseldorf (DE)
1 shared publication
- Contributors
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