Pravin Parajuli Source Confirmed

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

Researcher

National Center for Toxicological Research

unknown

4 h-index 8 pubs 164 cited

Research Areas

SARS-CoV-2 and COVID-19 Research Pharmacological Effects and Toxicity Studies Immune Response and Inflammation Protein Structure and Dynamics Microbial infections and disease research Molecular Biology Techniques and Applications

Links

ORCID

Is this your profile? Verify and claim your profile

OverviewAI-generated summary

Pravin Parajuli's research focuses on understanding molecular mechanisms related to health and disease. His work includes investigating the conformational changes of the SARS-CoV-2 spike protein's receptor binding domain and predicting B-cell antigenic epitopes. He has also studied preclinical in vitro models to assess the effects of exposure on intestinal epithelial cell permeability and cytotoxicity, using arsenite exposure as an example. Further research has explored targeting protein-protein interactions for immunomodulation, specifically examining a sunflower trypsin inhibitor analog peptidomimetic's effect on rheumatoid arthritis progression. Parajuli collaborates with researchers such as Sangeeta Khare and Kuppan Gokulan, both at the National Center for Toxicological Research, with whom he has co-authored multiple publications.

Metrics

  • h-index: 4
  • Publications: 8
  • Citations: 164

Selected Publications

  • Preclinical In Vitro Model to Assess the Changes in Permeability and Cytotoxicity of Polarized Intestinal Epithelial Cells during Exposure Mimicking Oral or Intravenous Routes: An Example of Arsenite Exposure (2022) DOI
  • Conformational Changes of the Receptor Binding Domain of SARS-CoV-2 Spike Protein and Prediction of a B-Cell Antigenic Epitope Using Structural Data (2021) DOI

Collaborators

Researchers in the database who share publications

Sangeeta Khare National Center for Toxicological Research 2 shared publications Kuppan Gokulan National Center for Toxicological Research 2 shared publications Marli S. P. Azevedo National Center for Toxicological Research 1 shared publication

Similar Researchers

Based on overlapping research topics

Kwame G. Yeboah Harding University Main Campus
Pharmacological Effects and Toxicity Studies Immune Response and Inflammation Microbial infections and disease research
Strong match 4 shared topics
Changhoon Oh University of Arkansas for Medical Sciences
Immune Response and Inflammation Protein Structure and Dynamics Microbial infections and disease research
Good match 4 shared topics
Chinmay Bera University of Arkansas for Medical Sciences
SARS-CoV-2 and COVID-19 Research Pharmacological Effects and Toxicity Studies Immune Response and Inflammation
Good match 4 shared topics
Shobanbabu Bommagani University of Arkansas for Medical Sciences
SARS-CoV-2 and COVID-19 Research Pharmacological Effects and Toxicity Studies Protein Structure and Dynamics
Good match 4 shared topics
Joseph Holthoff University of Arkansas for Medical Sciences
SARS-CoV-2 and COVID-19 Research Immune Response and Inflammation Microbial infections and disease research
Good match 4 shared topics
L.P.F. Balapiti-Modarage University of Arkansas for Medical Sciences
SARS-CoV-2 and COVID-19 Research Protein Structure and Dynamics Microbial infections and disease research
Good match 4 shared topics