Donghoon Yoon
Associate Professor
Also affiliated: The University of Texas MD Anderson Cancer Center (2003–2009); Baylor College of Medicine (2005–2006); University of Utah (2006–2015); Moffitt Cancer Center (2026)
Internal Med, College of Medicine
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Donghoon Yoon's research focuses on the molecular mechanisms underlying hematopoiesis, particularly the role of hypoxia and its signaling pathways in red blood cell development and iron homeostasis. His work has investigated the impact of hypoxia-inducible factors (HIFs) on erythropoiesis, examining how their deficiency or dysregulation affects signaling cascades and cellular processes such as mitophagy and ROS production. Yoon has also explored the involvement of microRNAs, specifically miR-451, in regulating erythroid differentiation. His research extends to metabolic consequences, including the relationship between HIF and glucose metabolism in conditions like Chuvash polycythemia. Yoon holds an h-index of 18 with over 1,200 citations across approximately 150 publications. He has collaborated extensively with researchers at the University of Arkansas for Medical Sciences, including Syed Hassan Mehdi, Ying-Zhi Xu, Samantha Kendrick, and Vijay Patel, with whom he shares numerous publications.
Metrics
- h-index: 18
- Publications: 139
- Citations: 1,272
Positions
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Associate Professor 2013–presentUniversity of Arkansas for Medical Sciences Internal Med, College of Medicine Institutional directory
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Assistant Professor 2006–2013University of Utah Internal Medicine ORCID
Selected Publications
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Self-actuated, pH-responsive hydrogel-driven microneedle actuator (pH-MA) patch for smart depth-controlled wound interface (2026)
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Abstract LB220: Can dietary calcium prevent myeloma onset (2026)
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Multimodal microneedle-based electrochemical sensors for continuous monitoring of the tumor microenvironment (2026)
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Abstract 2246: GLUT3 inhibition reduces metastatic potential of triple-negative breast cancer cells by modulating cell mechanics via the TEAD-VASP-Actin axis. (2026)
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Microneedle-Mediated Adaptive Phototherapy (MAP) Wound Patch with Microlens (2026)
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Micropocket-Integrated Microneedle Wound Dressing with PH-Responsive Actuation for Enhanced Drug Delivery (2025)
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Efficacy of Sigma Anti-bonding Molecule Calcium Carbonate on Bone Mineral Density (2025)
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Efficacy of Sigma Anti-bonding Molecule Calcium Carbonate (SAC) on Bone Mineral Density (BMD) in Asians (2025)
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The role of 7-dehydrocholesterol in inducing ER stress and apoptosis of head and neck squamous cell carcinoma (2025)
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Abstract 2650: Inhibition of glucose uptake by targeting GLUT3 reduces cell invasion and metastasis of triple-negative breast cancer cells through modulating AMPK-mediated cell mechanics (2025)
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Abstract 1605: Pretreatment of bone anabolic agent delays or prevents multiple myeloma progression (2025)
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Abstract A020: Elevated extracellular glucose level in tumor microenvironment by hyperglycemia increases glycolysis rate, stiffness, contractility, and motility of breast cancer cells through the cAMP-RhoA-Rock and AMPK-YAP-RhoA axes to promote metastasis (2024)
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Self-Assembly of Microstructured Protein Coatings with Programmable Functionality for Fluorescent Biosensors (2024)
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The Pigmentation of Blue Light Is Mediated by Both Melanogenesis Activation and Autophagy Inhibition through OPN3–TRPV1 (2024)
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Development of New Diffuse Large B Cell Lymphoma Mouse Models (2024)
Grants & Funding
As listed on this researcher's institutional profile.
- Study of Sigma Anti-Bonding Calcium (SAC) Role(s) in Multiple Myeloma and Cutaneous Wound Healing Calcium & Bone Health Institute Principal Investigator
- In Situ Imaging of Collagen Degradation Activity in Multiple Myeloma and Fibrosis Murine Models - Resubmission NIH/Office of the Director via University of Utah Principal Investigator
- Study of Sigma Anti-Bonding Calcium (SAC) Role(s) in Multiple Myeloma and Erythropoietin-Induced Osteoporosis Calcium & Bone Health Institute Principal Investigator
- Scientific and methodological advancement in liquid biopsies to further the development of lung cancer-based precision medicine U.S. Food and Drug Administration via Arkansas Research Alliance Co-Investigator
- Center for Musculoskeletal Disease Research (CMDR) NIH/Nat. Inst. of General Medical Sciences Select
Collaboration Network
Top Collaborators
- Visualizing collagen proteolysis by peptide hybridization: From 3D cell culture to in vivo imaging
- Extensive Remineralization of Large Pelvic Lytic Lesions Following Total Therapy Treatment in Patients With Multiple Myeloma
- Parathyroid hormone receptor mediates the anti-myeloma effect of proteasome inhibitors
- Daratumumab Single Agent and Daratumumab Plus Pomalidomide and Dexametasone in Relapsed/Refractory Multiple Myeloma: A Real Life Retrospective Evaluation
- Thymic PTH Increases After Thyroparathyroidectomy in C57BL/KaLwRij Mice
Showing 5 of 12 shared publications
- Bifunctional Inhibitor Reveals NEK2 as a Therapeutic Target and Regulator of Oncogenic Pathways in Lymphoma
- Animal Models of Multiple Myeloma Bone Disease
- An Improved Animal Model of Multiple Myeloma Bone Disease
- Development of New Diffuse Large B Cell Lymphoma Mouse Models
- Abstract 1655: Development of humanized diffuse large B-cell lymphoma mouse models
Showing 5 of 11 shared publications
- Extensive Remineralization of Large Pelvic Lytic Lesions Following Total Therapy Treatment in Patients With Multiple Myeloma
- Parathyroid hormone receptor mediates the anti-myeloma effect of proteasome inhibitors
- Daratumumab Single Agent and Daratumumab Plus Pomalidomide and Dexametasone in Relapsed/Refractory Multiple Myeloma: A Real Life Retrospective Evaluation
- Thymic PTH Increases After Thyroparathyroidectomy in C57BL/KaLwRij Mice
- Surgical thyroparathyroidectomy prevents progression of 5TGM1 murine multiple myeloma in vivo
Showing 5 of 6 shared publications
- Experimental Validation of Diffraction Lithography for Fabrication of Solid Microneedles
- Self-Assembly of Microstructured Protein Coatings with Programmable Functionality for Fluorescent Biosensors
- Self-assembly of microstructured protein coatings with programmable functionality for fluorescent biosensors
- Micropocket-Integrated Microneedle Wound Dressing with PH-Responsive Actuation for Enhanced Drug Delivery
- Microneedle-Mediated Adaptive Phototherapy (MAP) Wound Patch with Microlens
Showing 5 of 6 shared publications
- Thymic PTH Increases After Thyroparathyroidectomy in C57BL/KaLwRij Mice
- Surgical thyroparathyroidectomy prevents progression of 5TGM1 murine multiple myeloma in vivo
- Thymus-Derived PTH (TPTH) Is Increased after Thyroparathyroidectomy in C57BL6/Kalwrij Mice and Modulates Mouse Sensitivity to 5TGM1 Myeloma Cell Line
- Rigosertib, a Pan RAS Inhibitor, Decreases Mouse and Human Myeloma Cell Growth in Preclinical Models
- Surgical Control/Cure of 5TGM1 Murine Multiple Myeloma Model By Thyroparathyroidectomy
- The role of 7-dehydrocholesterol in inducing ER stress and apoptosis of head and neck squamous cell carcinoma
- Abstract 1605: Pretreatment of bone anabolic agent delays or prevents multiple myeloma progression
- Abstract 2650: Inhibition of glucose uptake by targeting GLUT3 reduces cell invasion and metastasis of triple-negative breast cancer cells through modulating AMPK-mediated cell mechanics
- Micropocket-Integrated Microneedle Wound Dressing with PH-Responsive Actuation for Enhanced Drug Delivery
- Abstract LB220: Can dietary calcium prevent myeloma onset
- Extensive Remineralization of Large Pelvic Lytic Lesions Following Total Therapy Treatment in Patients With Multiple Myeloma
- Daratumumab Single Agent and Daratumumab Plus Pomalidomide and Dexametasone in Relapsed/Refractory Multiple Myeloma: A Real Life Retrospective Evaluation
- Rigosertib, a Pan RAS Inhibitor, Decreases Mouse and Human Myeloma Cell Growth in Preclinical Models
- Higher Expressions of PTH Receptor Type 1 and/or 2 in Bone Marrow Is Associated to Longer Survival in Newly Diagnosed Myeloma Patients Enrolled in Total Therapy 3
- Extensive Remineralization of Large Pelvic Lytic Lesions Following Total Therapy Treatment in Patients With Multiple Myeloma
- Daratumumab Single Agent and Daratumumab Plus Pomalidomide and Dexametasone in Relapsed/Refractory Multiple Myeloma: A Real Life Retrospective Evaluation
- Thymic PTH Increases After Thyroparathyroidectomy in C57BL/KaLwRij Mice
- Higher Expressions of PTH Receptor Type 1 and/or 2 in Bone Marrow Is Associated to Longer Survival in Newly Diagnosed Myeloma Patients Enrolled in Total Therapy 3
- Bifunctional Inhibitor Reveals NEK2 as a Therapeutic Target and Regulator of Oncogenic Pathways in Lymphoma
- Development of New Diffuse Large B Cell Lymphoma Mouse Models
- Development of Humanized Diffuse Large B-Cell Lymphoma Mouse Models
- Abstract 1655: Development of humanized diffuse large B-cell lymphoma mouse models
- Experimental Validation of Diffraction Lithography for Fabrication of Solid Microneedles
- Advancing Drug Delivery with Pocket Microneedle Achieving Dual-Drug Synchronization
- Micropocket-Integrated Microneedle Wound Dressing with PH-Responsive Actuation for Enhanced Drug Delivery
- Multimodal microneedle-based electrochemical sensors for continuous monitoring of the tumor microenvironment
- Extensive Remineralization of Large Pelvic Lytic Lesions Following Total Therapy Treatment in Patients With Multiple Myeloma
- Daratumumab Single Agent and Daratumumab Plus Pomalidomide and Dexametasone in Relapsed/Refractory Multiple Myeloma: A Real Life Retrospective Evaluation
- Rigosertib, a Pan RAS Inhibitor, Decreases Mouse and Human Myeloma Cell Growth in Preclinical Models
- Extensive Remineralization of Large Pelvic Lytic Lesions Following Total Therapy Treatment in Patients With Multiple Myeloma
- Daratumumab Single Agent and Daratumumab Plus Pomalidomide and Dexametasone in Relapsed/Refractory Multiple Myeloma: A Real Life Retrospective Evaluation
- Higher Expressions of PTH Receptor Type 1 and/or 2 in Bone Marrow Is Associated to Longer Survival in Newly Diagnosed Myeloma Patients Enrolled in Total Therapy 3
- Visualizing collagen proteolysis by peptide hybridization: From 3D cell culture to in vivo imaging
- Liquid biopsy and its role in an advanced clinical trial for lung cancer
- Surgical thyroparathyroidectomy prevents progression of 5TGM1 murine multiple myeloma in vivo
- Animal Models of Multiple Myeloma Bone Disease
- Herbal Extracts from Lycii Radicis Corex and Achyranthes japonica Prevent Multiple Myeloma
- Development of Humanized Diffuse Large B-Cell Lymphoma Mouse Models
- Animal Models of Multiple Myeloma Bone Disease
- An Improved Animal Model of Multiple Myeloma Bone Disease
- Herbal Extracts from Lycii Radicis Corex and Achyranthes japonica Prevent Multiple Myeloma
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