Donghoon Yoon
Associate Professor
Also affiliated: The Graduate Center, CUNY (2009); The University of Texas MD Anderson Cancer Center (2003–2009); Baylor College of Medicine (2005–2006); Korea University (2015); University of Utah (2006–2015); University of Arkansas Medical Center (2023–2024); Institut Gustave Roussy (2012); University of Utah Hospital (2011); Ansan University (2015); University of Chicago Medical Center (2012); Kolon Life Science (South Korea) (2024); Winthrop Rockefeller Foundation (2018); Korea University (2025); GGG (France) (1992); Houston Graduate School of Theology (2009); The University of Texas at Austin (2025)
Faculty Researcher
Internal Med, College of Medicine
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Donghoon Yoon's research focuses on understanding and developing models for various diseases, with a particular emphasis on cancer and bone-related conditions. He has investigated multiple myeloma bone disease, developing improved animal models to study its progression and potential therapeutic targets. His work also extends to lymphoma, where he has identified NEK2 as a regulator of oncogenic pathways and a potential therapeutic target, as evidenced by his work on diffuse large B cell lymphoma mouse models. Additionally, Yoon has explored the role of specific molecular mechanisms in disease, such as the involvement of 7-dehydrocholesterol in head and neck squamous cell carcinoma and the pigmentation pathway mediated by OPN3–TRPV1 signaling. His research also includes advancements in drug delivery systems, such as microneedles designed for synchronized dual-drug release. Yoon is an Associate Professor in the Department of Internal Medicine at the University of Arkansas for Medical Sciences and has published extensively, with an h-index of 18 and over 1,200 citations.
Metrics
- h-index: 18
- Publications: 148
- Citations: 1,276
Selected Publications
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Abstract LB220: Can dietary calcium prevent myeloma onset (2026)
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Multimodal microneedle-based electrochemical sensors for continuous monitoring of the tumor microenvironment (2026)
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Abstract 2246: GLUT3 inhibition reduces metastatic potential of triple-negative breast cancer cells by modulating cell mechanics via the TEAD-VASP-Actin axis. (2026)
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Microneedle-Mediated Adaptive Phototherapy (MAP) Wound Patch with Microlens (2026)
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Micropocket-Integrated Microneedle Wound Dressing with PH-Responsive Actuation for Enhanced Drug Delivery (2025)
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Efficacy of Sigma Anti-bonding Molecule Calcium Carbonate on Bone Mineral Density (2025)
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Efficacy of Sigma Anti-bonding Molecule Calcium Carbonate (SAC) on Bone Mineral Density (BMD) in Asians (2025)
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The role of 7-dehydrocholesterol in inducing ER stress and apoptosis of head and neck squamous cell carcinoma (2025)
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Abstract 2650: Inhibition of glucose uptake by targeting GLUT3 reduces cell invasion and metastasis of triple-negative breast cancer cells through modulating AMPK-mediated cell mechanics (2025)
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Abstract 1605: Pretreatment of bone anabolic agent delays or prevents multiple myeloma progression (2025)
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Abstract A020: Elevated extracellular glucose level in tumor microenvironment by hyperglycemia increases glycolysis rate, stiffness, contractility, and motility of breast cancer cells through the cAMP-RhoA-Rock and AMPK-YAP-RhoA axes to promote metastasis (2024)
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Self-Assembly of Microstructured Protein Coatings with Programmable Functionality for Fluorescent Biosensors (2024)
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The Pigmentation of Blue Light Is Mediated by Both Melanogenesis Activation and Autophagy Inhibition through OPN3–TRPV1 (2024)
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Development of New Diffuse Large B Cell Lymphoma Mouse Models (2024)
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Self-assembly of microstructured protein coatings with programmable functionality for fluorescent biosensors (2024)
Grants & Funding
As listed on this researcher's institutional profile.
- Study of Sigma Anti-Bonding Calcium (SAC) Role(s) in Multiple Myeloma and Cutaneous Wound Healing Calcium & Bone Health Institute Principal Investigator
- In Situ Imaging of Collagen Degradation Activity in Multiple Myeloma and Fibrosis Murine Models - Resubmission NIH/Office of the Director via University of Utah Principal Investigator
- Study of Sigma Anti-Bonding Calcium (SAC) Role(s) in Multiple Myeloma and Erythropoietin-Induced Osteoporosis Calcium & Bone Health Institute Principal Investigator
- Scientific and methodological advancement in liquid biopsies to further the development of lung cancer-based precision medicine U.S. Food and Drug Administration via Arkansas Research Alliance Co-Investigator
- Center for Musculoskeletal Disease Research (CMDR) NIH/Nat. Inst. of General Medical Sciences Select
Collaboration Network
Top Collaborators
- Bifunctional Inhibitor Reveals NEK2 as a Therapeutic Target and Regulator of Oncogenic Pathways in Lymphoma
- Animal Models of Multiple Myeloma Bone Disease
- An Improved Animal Model of Multiple Myeloma Bone Disease
- The role of 7-dehydrocholesterol in inducing ER stress and apoptosis of head and neck squamous cell carcinoma
- Development of New Diffuse Large B Cell Lymphoma Mouse Models
Showing 5 of 8 shared publications
- Bifunctional Inhibitor Reveals NEK2 as a Therapeutic Target and Regulator of Oncogenic Pathways in Lymphoma
- Development of New Diffuse Large B Cell Lymphoma Mouse Models
- Development of Humanized Diffuse Large B-Cell Lymphoma Mouse Models
- Abstract 1655: Development of humanized diffuse large B-cell lymphoma mouse models
- Animal Models of Multiple Myeloma Bone Disease
- Herbal Extracts from Lycii Radicis Corex and Achyranthes japonica Prevent Multiple Myeloma
- Development of Humanized Diffuse Large B-Cell Lymphoma Mouse Models
- Animal Models of Multiple Myeloma Bone Disease
- An Improved Animal Model of Multiple Myeloma Bone Disease
- Herbal Extracts from Lycii Radicis Corex and Achyranthes japonica Prevent Multiple Myeloma
- Bifunctional Inhibitor Reveals NEK2 as a Therapeutic Target and Regulator of Oncogenic Pathways in Lymphoma
- Development of Humanized Diffuse Large B-Cell Lymphoma Mouse Models
- Abstract 1655: Development of humanized diffuse large B-cell lymphoma mouse models
- Experimental Validation of Diffraction Lithography for Fabrication of Solid Microneedles
- Advancing Drug Delivery with Pocket Microneedle Achieving Dual-Drug Synchronization
- Multimodal microneedle-based electrochemical sensors for continuous monitoring of the tumor microenvironment
- Herbal Extracts from Lycii Radicis Corex and Achyranthes japonica Prevent Multiple Myeloma
- Abstract 3828: Herbal extracts from lycii radicis corex and achyranthes japonica prevent multiple myeloma progression
- Herbal Extracts from Lycii Radicis Corex and Achyranthes japonica Prevent Multiple Myeloma
- Abstract 3828: Herbal extracts from lycii radicis corex and achyranthes japonica prevent multiple myeloma progression
- Bifunctional Inhibitor Reveals NEK2 as a Therapeutic Target and Regulator of Oncogenic Pathways in Lymphoma
- Development of Humanized Diffuse Large B-Cell Lymphoma Mouse Models
- Development of New Diffuse Large B Cell Lymphoma Mouse Models
- Abstract 1655: Development of humanized diffuse large B-cell lymphoma mouse models
- Experimental Validation of Diffraction Lithography for Fabrication of Solid Microneedles
- Advancing Drug Delivery with Pocket Microneedle Achieving Dual-Drug Synchronization
- Experimental Validation of Diffraction Lithography for Fabrication of Solid Microneedles
- Self-Assembly of Microstructured Protein Coatings with Programmable Functionality for Fluorescent Biosensors
- Experimental Validation of Diffraction Lithography for Fabrication of Solid Microneedles
- Self-Assembly of Microstructured Protein Coatings with Programmable Functionality for Fluorescent Biosensors
- Microneedle-Mediated Adaptive Phototherapy (MAP) Wound Patch with Microlens
- Multimodal microneedle-based electrochemical sensors for continuous monitoring of the tumor microenvironment
- Animal Models of Multiple Myeloma Bone Disease
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