Syed Hassan Mehdi
Instructor
Also affiliated: NED University of Engineering and Technology (2025); Aligarh Muslim University (2013); University of Arkansas Medical Center (2018–2023); Carnegie Mellon University Qatar (2025); Jamia Millia Islamia (2016–2021); Victoria University (2023); Carnegie Mellon University (2025)
Faculty Researcher
Internal Med, College of Medicine
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Syed Hassan Mehdi's research investigates mechanisms of cancer development and potential therapeutic targets, with a focus on lymphoma and multiple myeloma. His work explores the role of specific genes and cellular pathways in cancer progression, including the regulation of TWIST1, TOX, and cytokine gene expression in cutaneous T-cell lymphoma. Mehdi also studies the impact of mesenchymal stem cells on myeloma cell growth and dormancy, and the effects of 7-dehydrocholesterol on head and neck squamous cell carcinoma. He has contributed to the development of improved animal models for multiple myeloma bone disease and has published on the therapeutic potential of inhibitors targeting NEK2 in lymphoma. His research network includes extensive collaboration with colleagues at the University of Arkansas for Medical Sciences, such as Donghoon Yoon, Ying-Zhi Xu, Samantha Kendrick, and Vijay Patel.
Metrics
- h-index: 16
- Publications: 97
- Citations: 1,055
Selected Publications
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M2 Macrophage Polarization Characterizes an Immunosuppressive Microenvironment in Extracranial Arteriovenous Malformations (2026)
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Abstract LB220: Can dietary calcium prevent myeloma onset (2026)
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Multimodal microneedle-based electrochemical sensors for continuous monitoring of the tumor microenvironment (2026)
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Rescue of Angiopoietin‐2 Inhibits Proliferation of Lymphatic Malformation Endothelial Cells (2025)
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Micropocket-Integrated Microneedle Wound Dressing with PH-Responsive Actuation for Enhanced Drug Delivery (2025)
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The role of 7-dehydrocholesterol in inducing ER stress and apoptosis of head and neck squamous cell carcinoma (2025)
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Abstract 1605: Pretreatment of bone anabolic agent delays or prevents multiple myeloma progression (2025)
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A Pattern-Based Approach to Name and Address Parsing with Active Learning (2025)
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Mural Cells Initiate Endothelial-to-Mesenchymal Transition in Adjacent Endothelial Cells in Extracranial AVMs (2024)
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Development of New Diffuse Large B Cell Lymphoma Mouse Models (2024)
Grants & Funding
As listed on this researcher's institutional profile.
- Early Events in Alzheimer Pathogenesis NIH Co-Investigator
Collaboration Network
Top Collaborators
- Animal Models of Multiple Myeloma Bone Disease
- Bifunctional Inhibitor Reveals NEK2 as a Therapeutic Target and Regulator of Oncogenic Pathways in Lymphoma
- An Improved Animal Model of Multiple Myeloma Bone Disease
- The role of 7-dehydrocholesterol in inducing ER stress and apoptosis of head and neck squamous cell carcinoma
- Development of New Diffuse Large B Cell Lymphoma Mouse Models
Showing 5 of 11 shared publications
- Bifunctional Inhibitor Reveals NEK2 as a Therapeutic Target and Regulator of Oncogenic Pathways in Lymphoma
- Development of New Diffuse Large B Cell Lymphoma Mouse Models
- Development of Humanized Diffuse Large B-Cell Lymphoma Mouse Models
- Abstract 1655: Development of humanized diffuse large B-cell lymphoma mouse models
- Normal and cancer fibroblasts differentially regulate TWIST1, TOX and cytokine gene expression in cutaneous T-cell lymphoma
- Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling
- Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling
- Normal and cancer fibroblasts differentially regulate TWIST1, TOX and cytokine gene expression in cutaneous T-cell lymphoma
- Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling
- Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling
- Animal Models of Multiple Myeloma Bone Disease
- An Improved Animal Model of Multiple Myeloma Bone Disease
- Herbal Extracts from Lycii Radicis Corex and Achyranthes japonica Prevent Multiple Myeloma
- Bifunctional Inhibitor Reveals NEK2 as a Therapeutic Target and Regulator of Oncogenic Pathways in Lymphoma
- Development of Humanized Diffuse Large B-Cell Lymphoma Mouse Models
- Abstract 1655: Development of humanized diffuse large B-cell lymphoma mouse models
- Upregulated MicroRNA-21 Drives the Proliferation of Lymphatic Malformation Endothelial Cells by Inhibiting PDCD4
- Mural Cells Initiate Endothelial-to-Mesenchymal Transition in Adjacent Endothelial Cells in Extracranial AVMs
- Rescue of Angiopoietin‐2 Inhibits Proliferation of Lymphatic Malformation Endothelial Cells
- Upregulated MicroRNA-21 Drives the Proliferation of Lymphatic Malformation Endothelial Cells by Inhibiting PDCD4
- Mural Cells Initiate Endothelial-to-Mesenchymal Transition in Adjacent Endothelial Cells in Extracranial AVMs
- Rescue of Angiopoietin‐2 Inhibits Proliferation of Lymphatic Malformation Endothelial Cells
- Upregulated MicroRNA-21 Drives the Proliferation of Lymphatic Malformation Endothelial Cells by Inhibiting PDCD4
- Mural Cells Initiate Endothelial-to-Mesenchymal Transition in Adjacent Endothelial Cells in Extracranial AVMs
- Rescue of Angiopoietin‐2 Inhibits Proliferation of Lymphatic Malformation Endothelial Cells
- Bifunctional Inhibitor Reveals NEK2 as a Therapeutic Target and Regulator of Oncogenic Pathways in Lymphoma
- Upregulated MicroRNA-21 Drives the Proliferation of Lymphatic Malformation Endothelial Cells by Inhibiting PDCD4
- Rescue of Angiopoietin‐2 Inhibits Proliferation of Lymphatic Malformation Endothelial Cells
- Upregulated MicroRNA-21 Drives the Proliferation of Lymphatic Malformation Endothelial Cells by Inhibiting PDCD4
- Mural Cells Initiate Endothelial-to-Mesenchymal Transition in Adjacent Endothelial Cells in Extracranial AVMs
- Rescue of Angiopoietin‐2 Inhibits Proliferation of Lymphatic Malformation Endothelial Cells
- Herbal Extracts from Lycii Radicis Corex and Achyranthes japonica Prevent Multiple Myeloma
- Abstract 3828: Herbal extracts from lycii radicis corex and achyranthes japonica prevent multiple myeloma progression
- Herbal Extracts from Lycii Radicis Corex and Achyranthes japonica Prevent Multiple Myeloma
- Abstract 3828: Herbal extracts from lycii radicis corex and achyranthes japonica prevent multiple myeloma progression
- Bifunctional Inhibitor Reveals NEK2 as a Therapeutic Target and Regulator of Oncogenic Pathways in Lymphoma
- Development of Humanized Diffuse Large B-Cell Lymphoma Mouse Models
- Development of New Diffuse Large B Cell Lymphoma Mouse Models
- Abstract 1655: Development of humanized diffuse large B-cell lymphoma mouse models
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