Match tier Confirmed
Presence Current · Arkansas
Last published 2026
Sources OpenAlex · ORCID
Refreshed 2026-08-08

James Losey

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

Postdoctoral Fellow

Also affiliated: Swinburne University of Technology (2019)

Postdoc Researcher

7 h-index 19 pubs 126 cited

  • Molecular Dynamics Simulation
  • SARS-CoV-2
  • Protein Conformation
  • Spike Glycoprotein, Coronavirus
  • Proteins
  • Fluorescence Resonance Energy Transfer
  • Protein Domains
  • Angiotensin-Converting Enzyme 2
  • COVID-19
  • Humans
  • Protein Binding
  • Severe Acute Respiratory Syndrome
  • Severe acute respiratory syndrome-related coronavirus
  • Membrane Proteins
  • Plant Proteins

Biography and Research Information

OverviewAI-generated summary

James Losey's research focuses on computational studies of protein dynamics, particularly in the context of viral infections and protein engineering. He investigates the conformational changes of viral spike proteins, such as those found in SARS-CoV-2, using molecular dynamics simulations and fluorescence resonance energy transfer (FRET) techniques. His work also extends to developing computational approaches for designing recombinant proteins and understanding the embeddability problem in transition rate estimation. Losey has published on topics including secondary structure in intrinsically disordered protein regions and the computational elucidation of fusion protein effects on nanoparticle synthesis. He has a collaborative network within the University of Arkansas at Fayetteville, with multiple shared publications with researchers including Mahmoud Moradi and Vivek Govind Kumar. His work has resulted in 19 publications and 122 citations, with an h-index of 7.

Metrics

  • h-index: 7
  • Publications: 19
  • Citations: 126

Selected Publications

  • Simulating Freely Diffusing Single-Molecule FRET Data with Consideration of Protein Conformational Dynamics (2026)
    The Journal of Physical Chemistry B 1 citation DOI OpenAlex
  • BPS2025 - Along-the-path Markov models for state transition in a major facilitator superfamily transporter (2025)
    Biophysical Journal DOI OpenAlex
  • Transition rate estimation from along-the-path, unbiased, molecular dynamics simulations of a major facilitator superfamily transporter (2024)
    Biophysical Journal DOI OpenAlex
  • Addressing the Embeddability Problem in Transition Rate Estimation (2023)
    The Journal of Physical Chemistry A 4 citations DOI OpenAlex
  • Developing a rational approach to designing recombinant proteins for peptide-directed nanoparticle synthesis (2022)
    Nanoscale Advances 8 citations DOI OpenAlex
  • Simulating freely-diffusing single-molecule FRET data with consideration of protein conformational dynamics (2022)
    Biophysical Journal 1 citation DOI OpenAlex
  • Prefusion spike protein conformational changes are slower in SARS-CoV-2 than in SARS-CoV-1 (2022)
    Journal of Biological Chemistry 26 citations DOI OpenAlex
  • Addressing the embeddability problem in transition rate estimation from Markov state models (2022)
    Biophysical Journal DOI OpenAlex
  • Transient local secondary structure in the intrinsically disordered C-term of the Albino3 insertase (2021)
    Biophysical Journal 5 citations DOI OpenAlex
  • Computational Elucidation of Recombinant Fusion Protein Effect on Peptide-Directed Nanoparticles (2021)
    bioRxiv (Cold Spring Harbor Laboratory) 1 citation DOI OpenAlex
  • Integrating Molecular Dynamics and smFRET Data to Study the Conformational Ensemble of the C-Terminus of Albino3 Protein (2021)
    Biophysical Journal DOI OpenAlex
  • Differential Dynamic Behavior of Prefusion Spike Glycoproteins of Sars Coronaviruses 1 and 2 (2021)
    Biophysical Journal DOI OpenAlex
  • Simulating freely-diffusing single-molecule FRET data with consideration of protein conformational dynamics (2021)
    bioRxiv (Cold Spring Harbor Laboratory) DOI OpenAlex
  • Differential Dynamic Behavior of Prefusion Spike Proteins of SARS Coronaviruses 1 and 2 (2020)
    bioRxiv (Cold Spring Harbor Laboratory) 7 citations DOI OpenAlex
  • Addressing the Embeddability Problem in Transition Rate Estimation (2019)
    bioRxiv (Cold Spring Harbor Laboratory) 2 citations DOI OpenAlex

View all publications on OpenAlex →

Collaboration Network

32 Collaborators 8 Institutions 2 Countries

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