Match tier
Confirmed
Presence
Current · Arkansas
Last published
2024
Sources
OpenAlex · ORCID
Refreshed
2026-08-08
U
Ugochi H. Isu
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Researcher
Faculty Researcher
6 h-index
16 pubs
93 cited
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Ugochi H. Isu's research investigates protein structure and dynamics, particularly focusing on the conformational changes of viral spike proteins and cellular receptors. Her work utilizes molecular dynamics simulations to compare different structural states and experimental conditions, such as those found in X-ray versus Cryo-EM structures. Recent publications explore the differential behavior of the cannabinoid receptor 1 in active and inactive states, the role of cholesterol in Class C GPCRs, and the dynamics of SARS-CoV-2 spike proteins compared to SARS-CoV-1. Isu also studies the mechanisms of multidrug resistance transporters. Her research network includes collaborators from the University of Arkansas at Fayetteville, such as Mahmoud Moradi and Adithya Polasa, with whom she has co-authored multiple publications.
Metrics
- h-index: 6
- Publications: 16
- Citations: 93
Selected Publications
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Differential Behavior of Conformational Dynamics in Active and Inactive States of Cannabinoid Receptor 1 (2024)
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Differential Behavior of Conformational Dynamics in Active and Inactive States of Cannabinoid Receptor 1 (2024)
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Cholesterol Dependence of the Conformational Changes in Metabotropic Glutamate Receptor 1 (2024)
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Cholesterol-regulated conformational dynamics and stability of mGluR2 embedded in detergent micelles: Insights from molecular dynamics (2024)
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Differential behavior of conformational dynamics in active and inactive states of cannabinoid receptor 1 revealed by microsecond molecular dynamics simulation (2024)
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The Alternating Access Mechanism in Mammalian Multidrug Resistance Transporters and Their Bacterial Homologs (2023)
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Cholesterol in Class C GPCRs: Role, Relevance, and Localization (2023)
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Cholesterol dependence on the conformational changes of metabotropic glutamate receptor 1 (mGLuR1) (2023)
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Cholesterol in Class C GPCRs: Role, Relevance, and Localization (2023)
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Prefusion spike protein conformational changes are slower in SARS-CoV-2 than in SARS-CoV-1 (2022)
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Characterizing the roles of chemo-mechanical couplings in the differential behavior of SARS-CoV-1 and SARS-CoV-2 spike glycoprotein (2022)
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Structural dynamics of prefusion spike protein of SARS-CoV-2 and its variants (2022)
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Differential Dynamic Behavior of Prefusion Spike Glycoproteins of Sars Coronaviruses 1 and 2 (2021)
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Comparing the Dynamic Differences between X-ray and Cryo-EM Structures of Cannabinoid Receptor 1 using Molecular Dynamics Simulations (2021)
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Differential Dynamic Behavior of Prefusion Spike Proteins of SARS Coronaviruses 1 and 2 (2020)
Collaboration Network
Top Collaborators
Mahmoud Moradi
University of Arkansas at Fayetteville
14 shared publications
In database
- Prefusion spike protein conformational changes are slower in SARS-CoV-2 than in SARS-CoV-1
- Cholesterol in Class C GPCRs: Role, Relevance, and Localization
- The Alternating Access Mechanism in Mammalian Multidrug Resistance Transporters and Their Bacterial Homologs
- Cholesterol in Class C GPCRs: Role, Relevance, and Localization
- Differential Behavior of Conformational Dynamics in Active and Inactive States of Cannabinoid Receptor 1
Showing 5 of 14 shared publications
Adithya Polasa
University of Arkansas at Fayetteville
8 shared publications
In database
- Prefusion spike protein conformational changes are slower in SARS-CoV-2 than in SARS-CoV-1
- Differential Behavior of Conformational Dynamics in Active and Inactive States of Cannabinoid Receptor 1
- Comparing the Dynamic Differences between X-ray and Cryo-EM Structures of Cannabinoid Receptor 1 using Molecular Dynamics Simulations
- Cholesterol Dependence of the Conformational Changes in Metabotropic Glutamate Receptor 1
- Characterizing the roles of chemo-mechanical couplings in the differential behavior of SARS-CoV-1 and SARS-CoV-2 spike glycoprotein
Showing 5 of 8 shared publications
Shadi A. Badiee
University of Arkansas at Fayetteville
5 shared publications
In database
- Cholesterol in Class C GPCRs: Role, Relevance, and Localization
- The Alternating Access Mechanism in Mammalian Multidrug Resistance Transporters and Their Bacterial Homologs
- Cholesterol in Class C GPCRs: Role, Relevance, and Localization
- Cholesterol Dependence of the Conformational Changes in Metabotropic Glutamate Receptor 1
- Cholesterol-regulated conformational dynamics and stability of mGluR2 embedded in detergent micelles: Insights from molecular dynamics
Vivek Govind Kumar
University of Arkansas at Fayetteville
4 shared publications
In database
- Prefusion spike protein conformational changes are slower in SARS-CoV-2 than in SARS-CoV-1
- Comparing the Dynamic Differences between X-ray and Cryo-EM Structures of Cannabinoid Receptor 1 using Molecular Dynamics Simulations
- Differential Dynamic Behavior of Prefusion Spike Glycoproteins of Sars Coronaviruses 1 and 2
- Characterizing the roles of chemo-mechanical couplings in the differential behavior of SARS-CoV-1 and SARS-CoV-2 spike glycoprotein
Mortaza Derakhshani-Molayousefi
University of Arkansas at Fayetteville
4 shared publications
In database
- Cholesterol Dependence of the Conformational Changes in Metabotropic Glutamate Receptor 1
- Structural dynamics of prefusion spike protein of SARS-CoV-2 and its variants
- Characterizing the roles of chemo-mechanical couplings in the differential behavior of SARS-CoV-1 and SARS-CoV-2 spike glycoprotein
- Cholesterol dependence on the conformational changes of metabotropic glutamate receptor 1 (mGLuR1)
Ehsaneh Khodadadi
University of Arkansas at Fayetteville
4 shared publications
In database
- Cholesterol in Class C GPCRs: Role, Relevance, and Localization
- The Alternating Access Mechanism in Mammalian Multidrug Resistance Transporters and Their Bacterial Homologs
- Cholesterol in Class C GPCRs: Role, Relevance, and Localization
- Cholesterol-regulated conformational dynamics and stability of mGluR2 embedded in detergent micelles: Insights from molecular dynamics
Dylan S. Ogden
University of Arkansas at Fayetteville
2 shared publications
In database
- Prefusion spike protein conformational changes are slower in SARS-CoV-2 than in SARS-CoV-1
- Differential Dynamic Behavior of Prefusion Spike Glycoproteins of Sars Coronaviruses 1 and 2
James Losey
University of Arkansas at Fayetteville
2 shared publications
In database
- Prefusion spike protein conformational changes are slower in SARS-CoV-2 than in SARS-CoV-1
- Differential Dynamic Behavior of Prefusion Spike Glycoproteins of Sars Coronaviruses 1 and 2
Seyed Hamid Tabari
University of Arkansas at Fayetteville
2 shared publications
In database
- Cholesterol Dependence of the Conformational Changes in Metabotropic Glutamate Receptor 1
- Cholesterol dependence on the conformational changes of metabotropic glutamate receptor 1 (mGLuR1)
Ashkan F. Ghaan
North Carolina State University (US)
1 shared publication
- Cholesterol-regulated conformational dynamics and stability of mGluR2 embedded in detergent micelles: Insights from molecular dynamics
Similar Researchers
Based on overlapping research topics
Mahmoud Moradi
University of Arkansas at Fayetteville
Protein Structure and Dynamics
Molecular Dynamics Simulation
SARS-CoV-2 and COVID-19 Research
Maher Mansur
National Center for Toxicological Research
Protein Structure and Dynamics
SARS-CoV-2 and COVID-19 Research
Drug Transport and Resistance Mechanisms
Gourav Chakraborty
Arkansas State University
Protein Structure and Dynamics
Molecular Dynamics Simulation
Drug Transport and Resistance Mechanisms
Bailang Liu
National Center for Toxicological Research
Protein Structure and Dynamics
SARS-CoV-2 and COVID-19 Research
Receptor Mechanisms and Signaling
Shadi A. Badiee
University of Arkansas at Fayetteville
Protein Structure and Dynamics
Receptor Mechanisms and Signaling
Drug Transport and Resistance Mechanisms
Ahmed Shubbar
University of Arkansas at Fayetteville
Protein Structure and Dynamics
Molecular Dynamics Simulation
Drug Transport and Resistance Mechanisms