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Presence Current · Arkansas
Last published 2024
Sources OpenAlex · ORCID
Refreshed 2026-10-06

Vivek Govind Kumar

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7 h-index 32 pubs 190 cited

  • Molecular Dynamics Simulation
  • Humans
  • Protein Conformation
  • Protein Binding
  • Mutation
  • Heparin
  • Fibroblast Growth Factor 1
  • Proteins
  • Protein Domains
  • SARS-CoV-2
  • Spike Glycoprotein, Coronavirus
  • Binding Sites
  • Computer Simulation
  • Hydrogen Bonding
  • Mutant Proteins

Biography and Research Information

OverviewAI-generated summary

Vivek Govind Kumar's research employs molecular dynamics simulations to investigate protein structure and dynamics. His work has focused on understanding the conformational changes of viral proteins, such as the SARS-CoV-2 spike protein and influenza hemagglutinin. He also studies the stabilization mechanisms of human proteins, including fibroblast growth factor 1, by examining their interactions with molecules like heparin. Kumar's research addresses fundamental questions about protein folding, binding affinities, and the forces that govern protein stability and reversibility. His publication record includes studies on intrinsically disordered protein regions and the structural insights gained from combining experimental and computational approaches. Kumar collaborates with researchers at the University of Arkansas at Fayetteville and the University of Arkansas at Little Rock, with shared publications numbering as high as 14 with Mahmoud Moradi.

Metrics

  • h-index: 7
  • Publications: 32
  • Citations: 190

Selected Publications

  • Molecular Dynamics Investigation of the Influenza Hemagglutinin Conformational Changes in Acidic pH (2024)
    The Journal of Physical Chemistry B 5 citations DOI OpenAlex
  • Molecular dynamics investigation of the influenza hemagglutinin conformational changes in acidic pH (2024)
    bioRxiv (Cold Spring Harbor Laboratory) DOI OpenAlex
  • A purely physics-based computational binding affinity estimation from restrained umbrella sampling simulations (2024)
    Biophysical Journal 1 citation DOI OpenAlex
  • cpSRP43 Is Both Highly Flexible and Stable: Structural Insights Using a Combined Experimental and Computational Approach (2023)
    Journal of Chemical Information and Modeling 2 citations DOI OpenAlex
  • Structural effects of ALS-associated mutations on profilin (2023)
    Biophysical Journal DOI OpenAlex
  • Binding affinity estimation from restrained umbrella sampling simulations (2022)
    Nature Computational Science 65 citations DOI OpenAlex
  • Binding Affinity Estimation from Restrained Umbrella Sampling Simulations (2022)
    Research Square 4 citations DOI OpenAlex
  • Prefusion spike protein conformational changes are slower in SARS-CoV-2 than in SARS-CoV-1 (2022)
    Journal of Biological Chemistry 26 citations DOI OpenAlex
  • Molecular dynamics investigation of the ph-dependent influenza hemagglutinin conformational change (2022)
    Biophysical Journal DOI OpenAlex
  • Characterizing the roles of chemo-mechanical couplings in the differential behavior of SARS-CoV-1 and SARS-CoV-2 spike glycoprotein (2022)
    Biophysical Journal DOI OpenAlex
  • cpSRP43 is both highly flexible and stable: Structural insights using a combined experimental and computational approach (2022)
    bioRxiv (Cold Spring Harbor Laboratory) DOI OpenAlex
  • Binding Affinity Estimation From Restrained Umbrella Sampling Simulations (2021)
    bioRxiv (Cold Spring Harbor Laboratory) 2 citations DOI OpenAlex
  • Mechanistic Picture for Monomeric Human Fibroblast Growth Factor 1 Stabilization by Heparin Binding (2021)
    The Journal of Physical Chemistry B 11 citations DOI OpenAlex
  • Transient local secondary structure in the intrinsically disordered C-term of the Albino3 insertase (2021)
    Biophysical Journal 5 citations DOI OpenAlex
  • Characterization of the structural forces governing the reversibility of the thermal unfolding of the human acidic fibroblast growth factor (2021)
    Scientific Reports 12 citations DOI OpenAlex

View all publications on OpenAlex →

Collaboration Network

37 Collaborators 8 Institutions 2 Countries

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