Asim Shabbir
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Biography and Research Information
OverviewAI-generated summary
Asim Shabbir's research has focused on understanding the molecular mechanisms underlying various human diseases, with a significant emphasis on gastric cancer and metabolic disorders. His work has explored the tumor microenvironment, immune response regulation, and the identification of cancer-specific markers in gastric cancer. Shabbir has investigated the role of interferon gamma and the JAK-STAT pathway in regulating PD-L1 expression in gastric cancer and has contributed to identifying CD44v8-10 as a cancer-specific marker for gastric cancer stem cells.
Beyond oncology, his research extends to metabolic health, including studies on adipocyte ceramides and their impact on adipose tissue browning, inflammation, and metabolism. Shabbir has also been involved in developing organoid models for studying liver disease and has contributed to large-scale genomic sequencing projects. His scholarly output is substantial, evidenced by a high h-index of 44 and over 7,700 citations across more than 370 publications, designating him as a highly cited researcher.
Metrics
- h-index: 44
- Publications: 378
- Citations: 7,736
Selected Publications
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International Federation for the Surgery and Other Therapies for Obesity (IFSO) global consensus recommendations for optimizing outcomes after sleeve gastrectomy (2025)
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Ultrasound Responsive Nanotherapeutics for Multimodal Reprogramming of Obese Fat (2025)
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International expert consensus on surgery for type 2 diabetes mellitus (2025)
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Asia Pacific Gastroesophageal Cancer Congress (APGCC) 2024 consensus statement on stage 2 and 3 locally advanced gastric and Siewert 3 junctional adenocarcinoma (2025)
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Prognostic impact of positive peritoneal cytology (POPEC) in gastric cancer: Multi-centre European retrospective cohort study (2025)
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Ceramide-induced FGF13 impairs systemic metabolic health (2025)
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International expert consensus on the current status and future prospects of artificial intelligence in metabolic and bariatric surgery (2025)
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Cardiovascular-Liver-Metabolic Health: Recommendations in Screening, Diagnosis, and Management of Metabolic Dysfunction-Associated Steatotic Liver Disease in Cardiovascular Disease via Modified Delphi Approach (2024)
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Feasibility of long-range telesurgical robotic radical gastrectomy in a live porcine model (2024)
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Serum lipidomic signatures in patients with varying histological severity of metabolic-dysfunction associated steatotic liver disease (2024)
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Unveiling the prognostic significance of malignant ascites in advanced gastrointestinal cancers: a marker of peritoneal carcinomatosis burden (2024)
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Phase I PIANO trial—PIPAC-oxaliplatin and systemic nivolumab combination for gastric cancer peritoneal metastases: clinical and translational outcomes (2024)
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Spatially Resolved Niche and Tumor Microenvironmental Alterations in Gastric Cancer Peritoneal Metastases (2024)
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Resmetirom and Metabolic Dysfunction-Associated Steatohepatitis: Perspectives on Multidisciplinary Management from Global Healthcare Professionals (2024)
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Metabolic and Bariatric Surgeon Criteria—An International Experts’ Consensus (2024)
Collaboration Network
Top Collaborators
- Single-Cell Atlas of Lineage States, Tumor Microenvironment, and Subtype-Specific Expression Programs in Gastric Cancer
- PD ‐L1 expression is mainly regulated by interferon gamma associated with JAK ‐ STAT pathway in gastric cancer
- Development and validation of a serum microRNA biomarker panel for detecting gastric cancer in a high-risk population
- CD44v8-10 Is a Cancer-Specific Marker for Gastric Cancer Stem Cells
- Longer Examination Time Improves Detection of Gastric Cancer During Diagnostic Upper Gastrointestinal Endoscopy
Showing 5 of 111 shared publications
- Single-Cell Atlas of Lineage States, Tumor Microenvironment, and Subtype-Specific Expression Programs in Gastric Cancer
- Enhanced recovery versus conventional care in gastric cancer surgery: a meta-analysis of randomized and non-randomized controlled trials
- PIPAC-OX: A Phase I Study of Oxaliplatin-Based Pressurized Intraperitoneal Aerosol Chemotherapy in Patients with Peritoneal Metastases
- Pouch Versus No Pouch Following Total Gastrectomy: Meta-analysis of Randomized and Non-randomized Studies
- Spatially Resolved Niche and Tumor Microenvironmental Alterations in Gastric Cancer Peritoneal Metastases
Showing 5 of 37 shared publications
- Single-Cell Atlas of Lineage States, Tumor Microenvironment, and Subtype-Specific Expression Programs in Gastric Cancer
- PD ‐L1 expression is mainly regulated by interferon gamma associated with JAK ‐ STAT pathway in gastric cancer
- Development and validation of a serum microRNA biomarker panel for detecting gastric cancer in a high-risk population
- Hedgehog transcriptional effector GLI mediates mTOR-Induced PD-L1 expression in gastric cancer organoids
- PIPAC-OX: A Phase I Study of Oxaliplatin-Based Pressurized Intraperitoneal Aerosol Chemotherapy in Patients with Peritoneal Metastases
Showing 5 of 31 shared publications
- Laparoscopic versus open ventral hernia mesh repair: a prospective study
- Endoscopic submucosal dissection of gastric lesions by using a Master and Slave Transluminal Endoscopic Robot (MASTER)
- Bariatric Surgery in Asia in the Last 5 Years (2005–2009)
- Ventral hernia and obesity: is there a consensus?
- Accumulation of CD11c+CD163+ Adipose Tissue Macrophages through Upregulation of Intracellular 11β-HSD1 in Human Obesity
Showing 5 of 22 shared publications
- PD ‐L1 expression is mainly regulated by interferon gamma associated with JAK ‐ STAT pathway in gastric cancer
- Accumulation of CD11c+CD163+ Adipose Tissue Macrophages through Upregulation of Intracellular 11β-HSD1 in Human Obesity
- Therapeutic potential of highly cytotoxic natural killer cells for gastric cancer
- Acquired Resistance to FGFR Inhibitor in Diffuse-Type Gastric Cancer through an AKT-Independent PKC-Mediated Phosphorylation of GSK3β
- Inhibition of MMP activity can restore NKG2D ligand expression in gastric cancer, leading to improved NK cell susceptibility
Showing 5 of 15 shared publications
- Spatially Resolved Niche and Tumor Microenvironmental Alterations in Gastric Cancer Peritoneal Metastases
- Outcomes of a Phase II Study of Intraperitoneal Paclitaxel plus Systemic Capecitabine and Oxaliplatin (XELOX) for Gastric Cancer with Peritoneal Metastases
- Phase I PIANO trial—PIPAC-oxaliplatin and systemic nivolumab combination for gastric cancer peritoneal metastases: clinical and translational outcomes
- Kamikawa Double-Flap Reconstruction After Minimally Invasive Ivor-Lewis Esophagectomy
- Outcomes of a phase II study of intraperitoneal paclitaxel plus systemic capecitabine and oxaliplatin (XELOX) for gastric cancer with peritoneal metastases.
Showing 5 of 14 shared publications
- Single-Cell Atlas of Lineage States, Tumor Microenvironment, and Subtype-Specific Expression Programs in Gastric Cancer
- PIPAC-OX: A Phase I Study of Oxaliplatin-Based Pressurized Intraperitoneal Aerosol Chemotherapy in Patients with Peritoneal Metastases
- Outcomes of a Phase II Study of Intraperitoneal Paclitaxel plus Systemic Capecitabine and Oxaliplatin (XELOX) for Gastric Cancer with Peritoneal Metastases
- Real-Time Tumor Gene Expression Profiling to Direct Gastric Cancer Chemotherapy: Proof-of-Concept “3G” Trial
- Clinical relevance of PD-1 positive CD8 T-cells in gastric cancer
Showing 5 of 13 shared publications
- Patient Selection in One Anastomosis/Mini Gastric Bypass—an Expert Modified Delphi Consensus
- Best practice approach for redo-surgeries after sleeve gastrectomy, an expert's modified Delphi consensus
- Current recommendations for procedure selection in class I and II obesity developed by an expert modified Delphi consensus
- Resmetirom and Metabolic Dysfunction-Associated Steatohepatitis: Perspectives on Multidisciplinary Management from Global Healthcare Professionals
- International expert consensus on the current status and future prospects of artificial intelligence in metabolic and bariatric surgery
Showing 5 of 13 shared publications
- PD ‐L1 expression is mainly regulated by interferon gamma associated with JAK ‐ STAT pathway in gastric cancer
- Longer Examination Time Improves Detection of Gastric Cancer During Diagnostic Upper Gastrointestinal Endoscopy
- Outcomes of a Phase II Study of Intraperitoneal Paclitaxel plus Systemic Capecitabine and Oxaliplatin (XELOX) for Gastric Cancer with Peritoneal Metastases
- Gastro-esophageal reflux disease (GERD) after peroral endoscopic myotomy (POEM)
- Mo1579 Duration of Endoscopic Examination Significantly Impacts Detection Rates of Neoplastic Lesions During Diagnostic Upper Endoscopy
Showing 5 of 12 shared publications
- PIPAC-OX: A Phase I Study of Oxaliplatin-Based Pressurized Intraperitoneal Aerosol Chemotherapy in Patients with Peritoneal Metastases
- Outcomes of a Phase II Study of Intraperitoneal Paclitaxel plus Systemic Capecitabine and Oxaliplatin (XELOX) for Gastric Cancer with Peritoneal Metastases
- Study protocol: phase 1 dose escalating study of Pressurized Intra-Peritoneal Aerosol Chemotherapy (PIPAC) with oxaliplatin in peritoneal metastasis
- Clinical relevance of PD-1 positive CD8 T-cells in gastric cancer
- Phase I PIANO trial—PIPAC-oxaliplatin and systemic nivolumab combination for gastric cancer peritoneal metastases: clinical and translational outcomes
Showing 5 of 11 shared publications
- Cardiovascular-Liver-Metabolic Health: Recommendations in Screening, Diagnosis, and Management of Metabolic Dysfunction-Associated Steatotic Liver Disease in Cardiovascular Disease via Modified Delphi Approach
- The placebo response rate and nocebo events in obesity pharmacological trials. A systematic review and meta-analysis
- Effectiveness of an Artificial Intelligence-Assisted App for Improving Eating Behaviors: Mixed Methods Evaluation
- The prognostic value of including non‐alcoholic fatty liver disease in the definition of metabolic syndrome
- Anthropometric and cardiometabolic effects of polyphenols in people with overweight and obesity: an umbrella review
Showing 5 of 11 shared publications
- Single-Cell Atlas of Lineage States, Tumor Microenvironment, and Subtype-Specific Expression Programs in Gastric Cancer
- Large-Scale Whole-Genome Sequencing of Three Diverse Asian Populations in Singapore
- AQP5 enriches for stem cells and cancer origins in the distal stomach
- Acquired Resistance to FGFR Inhibitor in Diffuse-Type Gastric Cancer through an AKT-Independent PKC-Mediated Phosphorylation of GSK3β
- Large-scale whole-genome sequencing of three diverse Asian populations in Singapore
Showing 5 of 10 shared publications
- Development and validation of a serum microRNA biomarker panel for detecting gastric cancer in a high-risk population
- AQP5 enriches for stem cells and cancer origins in the distal stomach
- Fiberoptic Confocal Raman Spectroscopy for Real-Time In Vivo Diagnosis of Dysplasia in Barrett's Esophagus
- Real-time Raman spectroscopy for in vivo, online gastric cancer diagnosis during clinical endoscopic examination
- Fiber‐optic Raman spectroscopy probes gastric carcinogenesis in vivo at endoscopy
Showing 5 of 9 shared publications
- Enhanced recovery versus conventional care in gastric cancer surgery: a meta-analysis of randomized and non-randomized controlled trials
- Pouch Versus No Pouch Following Total Gastrectomy: Meta-analysis of Randomized and Non-randomized Studies
- Conversion Surgery Post-Intraperitoneal Paclitaxel and Systemic Chemotherapy for Gastric Cancer Carcinomatosis Peritonei. Are We Ready?
- Metabolic outcomes after revisional bariatric surgery: a systematic review and meta-analysis
- The placebo response rate and nocebo events in obesity pharmacological trials. A systematic review and meta-analysis
Showing 5 of 9 shared publications
- Best practice approach for redo-surgeries after sleeve gastrectomy, an expert's modified Delphi consensus
- Bariatric Evaluation Through AI: a Survey of Expert Opinions Versus ChatGPT-4 (BETA-SEOV)
- The First Modified Delphi Consensus Statement for Resuming Bariatric and Metabolic Surgery in the COVID-19 Times
- Current recommendations for procedure selection in class I and II obesity developed by an expert modified Delphi consensus
- Resmetirom and Metabolic Dysfunction-Associated Steatohepatitis: Perspectives on Multidisciplinary Management from Global Healthcare Professionals
Showing 5 of 9 shared publications
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