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Current · Arkansas
Last published
2023
Sources
OpenAlex · ORCID
Refreshed
2026-10-07
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Maria Theresa E. Montales
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Also affiliated: Arkansas Children's Hospital (2014); University of Michigan (2015); Columbia University Irving Medical Center (2015); University of Arkansas Medical Center (2015–2017); Harlem Hospital Center (2015); Michigan Medicine (2015); Arkansas Children's Nutrition Center (2011–2013); Arkansas Children's Research Institute (2014); Columbia University (2015)
12 h-index
22 pubs
2,054 cited
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Maria Theresa E. Montales investigates the molecular mechanisms underlying metabolic disorders and cancer. Her research has focused on the role of specific enzymes and proteins in conditions such as obesity and hepatocellular carcinoma. Recent publications include studies on how Malic Enzyme 1 (ME1) contributes to adiposity and hepatic steatosis in mice, and how Krüppel-like Factor 9 (KLF9) can suppress oxidative stress in mice fed a high-fat diet, potentially impacting hepatocellular carcinoma development.
Montales's work also delves into the cellular pathways involving PTEN and Wnt1 proteins, with a focus on their roles in cancer progression. Her research utilizes animal models, including transgenic mice, and cell culture techniques to explore these complex biological processes. Her scholarship metrics indicate a body of work with an h-index of 11 and over 1,900 citations across 20 publications. She collaborates with researchers at the University of Arkansas for Medical Sciences, including Frank A. Simmen and Iad Alhallak.
Metrics
- h-index: 12
- Publications: 22
- Citations: 2,054
Selected Publications
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Malic Enzyme 1 (ME1) Promotes Adiposity and Hepatic Steatosis and Induces Circulating Insulin and Leptin in Obese Female Mice (2023)
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Krüppel-like Factor 9 (KLF9) Suppresses Hepatocellular Carcinoma (HCC)-Promoting Oxidative Stress and Inflammation in Mice Fed High-Fat Diet (2022)
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Metformin Promotes Anti-tumor Biomarkers in Human Endometrial Cancer Cells (2020)
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Clinical Review of Antidiabetic Drugs: Implications for Type 2 Diabetes Mellitus Management (2017)
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Metabolic history impacts mammary tumor epithelial hierarchy and early drug response in mice (2016)
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HIV-Associated TB Syndemic: A Growing Clinical Challenge Worldwide (2015)
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Metformin and soybean-derived bioactive molecules attenuate the expansion of stem cell-like epithelial subpopulation and confer apoptotic sensitivity in human colon cancer cells (2015)
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Tuberculosis reinfection in a pregnant cystic fibrosis patient (2015)
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The Krüppel-like factors in female reproductive system pathologies (2015)
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Mycobacterium tuberculosis infection in a HIV-positive patient (2015)
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Pulmonary tuberculosis in a patient with cystic fibrosis (2015)
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Maternal high fat diet promotion of mammary tumor risk in adult progeny is associated with early expansion of mammary cancer stem‐like cells and increased maternal oxidative environment (2013)
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Maternal metabolic changes with dietary intake of blueberry during pregnancy and lactation predispose adult progeny to lower mammary tumor growth rate (2013)
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Dietary suppression of the mammary CD29hiCD24+ epithelial subpopulation and its cytokine/chemokine transcriptional signatures modifies mammary tumor risk in MMTV-Wnt1 transgenic mice (2013)
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Soy Foods: Towards the Development of Novel Therapeutics for Breast Cancer (2013)
Collaboration Network
Top Collaborators
Rosalia C. M. Simmen
Winthrop Rockefeller Foundation
7 shared publications
In database
- Metformin and soybean-derived bioactive molecules attenuate the expansion of stem cell-like epithelial subpopulation and confer apoptotic sensitivity in human colon cancer cells
- Malic Enzyme 1 (ME1) Promotes Adiposity and Hepatic Steatosis and Induces Circulating Insulin and Leptin in Obese Female Mice
- Metformin Promotes Anti-tumor Biomarkers in Human Endometrial Cancer Cells
- Krüppel-like Factor 9 (KLF9) Suppresses Hepatocellular Carcinoma (HCC)-Promoting Oxidative Stress and Inflammation in Mice Fed High-Fat Diet
- Dietary suppression of the mammary CD29hiCD24+ epithelial subpopulation and its cytokine/chemokine transcriptional signatures modifies mammary tumor risk in MMTV-Wnt1 transgenic mice
Showing 5 of 7 shared publications
John Mark P. Pabona
University of Arkansas for Medical Sciences (US)
6 shared publications
- The soybean peptide lunasin promotes apoptosis of mammary epithelial cells via induction of tumor suppressor PTEN: similarities and distinct actions from soy isoflavone genistein
- The Krüppel-like factors in female reproductive system pathologies
- Malic Enzyme 1 (ME1) Promotes Adiposity and Hepatic Steatosis and Induces Circulating Insulin and Leptin in Obese Female Mice
- Metformin Promotes Anti-tumor Biomarkers in Human Endometrial Cancer Cells
- Dietary suppression of the mammary CD29hiCD24+ epithelial subpopulation and its cytokine/chemokine transcriptional signatures modifies mammary tumor risk in MMTV-Wnt1 transgenic mice
Showing 5 of 6 shared publications
Frank A. Simmen
Winthrop Rockefeller Foundation
6 shared publications
In database
- Metformin and soybean-derived bioactive molecules attenuate the expansion of stem cell-like epithelial subpopulation and confer apoptotic sensitivity in human colon cancer cells
- Malic Enzyme 1 (ME1) Promotes Adiposity and Hepatic Steatosis and Induces Circulating Insulin and Leptin in Obese Female Mice
- Metformin Promotes Anti-tumor Biomarkers in Human Endometrial Cancer Cells
- Krüppel-like Factor 9 (KLF9) Suppresses Hepatocellular Carcinoma (HCC)-Promoting Oxidative Stress and Inflammation in Mice Fed High-Fat Diet
- Metabolic history impacts mammary tumor epithelial hierarchy and early drug response in mice
Showing 5 of 6 shared publications
Rosalia C.M. Simmen
Arkansas Children's Nutrition Center
6 shared publications
In database
- The soybean peptide lunasin promotes apoptosis of mammary epithelial cells via induction of tumor suppressor PTEN: similarities and distinct actions from soy isoflavone genistein
- The Krüppel-like factors in female reproductive system pathologies
- Repression of mammosphere formation in breast cancer cells by soy isoflavone genistein and blueberry polyphenols
- Maternal metabolic changes with dietary intake of blueberry during pregnancy and lactation predispose adult progeny to lower mammary tumor growth rate
- Maternal high fat diet promotion of mammary tumor risk in adult progeny is associated with early expansion of mammary cancer stem‐like cells and increased maternal oxidative environment
Showing 5 of 6 shared publications
Naveen Patil
Arkansas Department of Health (US)
5 shared publications
- Clinical Review of Antidiabetic Drugs: Implications for Type 2 Diabetes Mellitus Management
- HIV-Associated TB Syndemic: A Growing Clinical Challenge Worldwide
- Mycobacterium tuberculosis infection in a HIV-positive patient
- Pulmonary tuberculosis in a patient with cystic fibrosis
- Tuberculosis reinfection in a pregnant cystic fibrosis patient
Omar M. Rahal
Arkansas Children's Nutrition Center (US)
4 shared publications
- The soybean peptide lunasin promotes apoptosis of mammary epithelial cells via induction of tumor suppressor PTEN: similarities and distinct actions from soy isoflavone genistein
- Dietary suppression of the mammary CD29hiCD24+ epithelial subpopulation and its cytokine/chemokine transcriptional signatures modifies mammary tumor risk in MMTV-Wnt1 transgenic mice
- Soy Foods: Towards the Development of Novel Therapeutics for Breast Cancer
- Repression of mammosphere formation in breast cancer cells by soy isoflavone genistein and blueberry polyphenols
Melissa E. Heard
University of Arkansas Medical Center (US)
3 shared publications
- The Krüppel-like factors in female reproductive system pathologies
- Dietary suppression of the mammary CD29hiCD24+ epithelial subpopulation and its cytokine/chemokine transcriptional signatures modifies mammary tumor risk in MMTV-Wnt1 transgenic mice
- Soy Foods: Towards the Development of Novel Therapeutics for Breast Cancer
Asween Marco
University of Arkansas at Little Rock (US)
3 shared publications
- Clinical Review of Antidiabetic Drugs: Implications for Type 2 Diabetes Mellitus Management
- Pulmonary tuberculosis in a patient with cystic fibrosis
- Tuberculosis reinfection in a pregnant cystic fibrosis patient
Alexandria Beebe
Arkansas Department of Health
3 shared publications
In database
- Clinical Review of Antidiabetic Drugs: Implications for Type 2 Diabetes Mellitus Management
- HIV-Associated TB Syndemic: A Growing Clinical Challenge Worldwide
- Mycobacterium tuberculosis infection in a HIV-positive patient
Arun Chaudhury
Arkansas Department of Agriculture (US)
3 shared publications
- Clinical Review of Antidiabetic Drugs: Implications for Type 2 Diabetes Mellitus Management
- HIV-Associated TB Syndemic: A Growing Clinical Challenge Worldwide
- Mycobacterium tuberculosis infection in a HIV-positive patient
Iad Alhallak
University of Arkansas for Medical Sciences
3 shared publications
In database
- Malic Enzyme 1 (ME1) Promotes Adiposity and Hepatic Steatosis and Induces Circulating Insulin and Leptin in Obese Female Mice
- Metformin Promotes Anti-tumor Biomarkers in Human Endometrial Cancer Cells
- Krüppel-like Factor 9 (KLF9) Suppresses Hepatocellular Carcinoma (HCC)-Promoting Oxidative Stress and Inflammation in Mice Fed High-Fat Diet
Ahmed Al‐Dwairi
Jordan University of Science and Technology (JO)
2 shared publications
- Malic Enzyme 1 (ME1) Promotes Adiposity and Hepatic Steatosis and Induces Circulating Insulin and Leptin in Obese Female Mice
- Soy Foods: Towards the Development of Novel Therapeutics for Breast Cancer
Adam R. Brown
University of Arkansas for Medical Sciences (US)
2 shared publications
- Krüppel-like Factor 9 (KLF9) Suppresses Hepatocellular Carcinoma (HCC)-Promoting Oxidative Stress and Inflammation in Mice Fed High-Fat Diet
- Soy Foods: Towards the Development of Novel Therapeutics for Breast Cancer
Nutan Bhaskar
University of Arkansas for Medical Sciences (US)
2 shared publications
- Pulmonary tuberculosis in a patient with cystic fibrosis
- Tuberculosis reinfection in a pregnant cystic fibrosis patient
Penchala Mittadodla
University of Arkansas for Medical Sciences (US)
2 shared publications
- Pulmonary tuberculosis in a patient with cystic fibrosis
- Tuberculosis reinfection in a pregnant cystic fibrosis patient
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