Ravi P. Cholia
Research Instructor
Formerly Arkansas Affiliated with UAMS through 2022.
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Ravi P. Cholia's research investigates the role of the enzyme APE1/Ref-1 in various human diseases, with a particular focus on its modulation by phytochemicals and its connection to glioblastoma. His work has explored how oxidative stress influences the invasive potential of glioblastoma cells through the activation of key enzymes like PKM2, ENPP2, and APE1. Cholia has also examined the DNA repair and redox activities of APE1/Ref-1, assessing their limitations and scope for anticancer drug development. His research includes in vitro studies on the effects of hydrogen peroxide and glucose oxidase on glioblastoma cell survival mechanisms and antioxidant potential. Additionally, he has investigated the multifaceted role of ENPP2 in human diseases and the anticancer activity of certain compounds against glioma cells via topoisomerase II inhibition. His recent work also touches on nicotinamide riboside's effects on cisplatin-induced peripheral neuropathy.
Metrics
- h-index: 7
- Publications: 10
- Citations: 327
Positions
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Research Instructor 2023–presentUniversity of Arkansas for Medical Sciences Radiation Division Institutional directory
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Postdoctoral Fellow 2018–2023University of Arkansas for Medical Sciences Radiation Oncology ORCID
Selected Publications
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Nicotinamide Riboside Alleviates Cisplatin-Induced Peripheral Neuropathy via SIRT2 Activation (2022)
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Nicotinamide riboside alleviates cisplatin-induced peripheral neuropathy via SIRT2 activation (2022)
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A short review on cross-link between pyruvate kinase (PKM2) and Glioblastoma Multiforme (2021)
Grants & Funding
As listed on this researcher's institutional profile.
- The novel role of Sirtuin 2 in regulation of transcription-associated DNA damage repair NIH
Collaboration Network
Top Collaborators
- A short review on cross-link between pyruvate kinase (PKM2) and Glioblastoma Multiforme
- A short review on cross-link between pyruvate kinase (PKM2) and Glioblastoma Multiforme
- A short review on cross-link between pyruvate kinase (PKM2) and Glioblastoma Multiforme
- A short review on cross-link between pyruvate kinase (PKM2) and Glioblastoma Multiforme
- Nicotinamide riboside alleviates cisplatin-induced peripheral neuropathy via SIRT2 activation
- Nicotinamide riboside alleviates cisplatin-induced peripheral neuropathy via SIRT2 activation
- Nicotinamide riboside alleviates cisplatin-induced peripheral neuropathy via SIRT2 activation
- Nicotinamide riboside alleviates cisplatin-induced peripheral neuropathy via SIRT2 activation
- Nicotinamide riboside alleviates cisplatin-induced peripheral neuropathy via SIRT2 activation
- Nicotinamide Riboside Alleviates Cisplatin-Induced Peripheral Neuropathy via SIRT2 Activation
- Nicotinamide Riboside Alleviates Cisplatin-Induced Peripheral Neuropathy via SIRT2 Activation
- Nicotinamide Riboside Alleviates Cisplatin-Induced Peripheral Neuropathy via SIRT2 Activation
- Nicotinamide Riboside Alleviates Cisplatin-Induced Peripheral Neuropathy via SIRT2 Activation
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