Chandrabose Karthikeyan

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

Associate Staff Scientist

UAMS

Also affiliated: Tamil Nadu Agricultural University (2025); Rajiv Gandhi Technical University (2007–2020); Annamalai University (2010–2019); Indian Institute of Information Technology Design and Manufacturing Jabalpur (2025); Indian Institute of Technology Madras (2024); Health Sciences North (2021); Rajiv Gandhi University of Health Sciences (2018); Indira Gandhi National Tribal University (2018–2026); HLL Lifecare (India) (2021); Institute of Medical Sciences and Sum Hospital (2006); Bhopal Memorial Hospital & Research Centre (2018); Bentham Science Publishers (China) (2014); Bentham Science Publishers (United Arab Emirates) (2014); Indian Institute of Technology Indore (2006); Koneru Lakshmaiah Education Foundation (2020–2021); Bharati Vidyapeeth Deemed University (2021)

Staff Researcher

28 h-index 149 pubs 2,446 cited

Research Areas

Biomedical Subjects

Links

ORCID

OverviewAI-generated summary

Chandrabose Karthikeyan's research focuses on the development and application of nanomaterials for targeted drug delivery, particularly in cancer therapy. He investigates the functionalization of materials such as multi-walled carbon nanotubes and graphene quantum dots with specific ligands to enhance their efficacy in delivering chemotherapeutic agents like doxorubicin to cancer cells. His work also addresses the inherent toxicity of carbon nanotubes, exploring methods like curcumin coating to mitigate these effects.

His research extends to exploring novel nanocarriers for drug delivery, including lysinated multiwalled carbon nanotubes conjugated with carbohydrate ligands for targeted delivery to breast cancer cells, and multifunctional graphene quantum dots for receptor targeting, drug delivery, and bioimaging in pancreatic cancer. Karthikeyan also has an interest in applying computational methods, such as quantitative structure-activity relationship (QSAR) modeling, to drug design and prediction. He has explored the use of deep learning for predicting disease stages, as seen in his work on diabetic retinopathy.

Karthikeyan's publication record includes studies on the pharmacological effects of various agents, the molecular mechanisms of diseases, and the synthesis and application of nanomaterials. His work has been cited over 2,400 times, contributing to a body of knowledge in nanomedicine and cancer therapeutics. He has collaborated with researchers at the University of Arkansas for Medical Sciences on several projects.

Metrics

h-index: 28
Publications: 149
Citations: 2,446

Selected Publications

Vacuolization as a Novel Approach to Cancer Therapy (2026)

Journal of Biochemical and Molecular Toxicology DOI OpenAlex
Abstract LB315: Targeting endolysosomal trafficking to overcome paclitaxel resistance in triple-negative breast cancer (2026)

Cancer Research DOI OpenAlex
The Therapeutic Promise of Kojic Acid: A Comprehensive Review (2026)

Mini-Reviews in Medicinal Chemistry DOI OpenAlex
Correction: Updated insights on ASK1 signaling: mechanisms, regulation, and therapeutic potential in diseases (2025)

Molecular and Cellular Biochemistry DOI OpenAlex
Patent landscape in hydroxamic acid-based HDAC inhibitors (2020–2024): structure–activity relationships and mechanistic insights (2025)

Expert Opinion on Therapeutic Patents DOI OpenAlex
The hidden hand of endoplasmic reticulum stress in anticancer drug resistance (2025)

Critical Reviews in Oncology/Hematology 4 citations DOI OpenAlex
Identification and Mechanistic Profiling of Indolin‐2‐One Derivatives That Induce ROS‐Driven Intrinsic Apoptosis in Prostate and Colorectal Cancer Cells (2025)

Journal of Biochemical and Molecular Toxicology DOI OpenAlex
Thienopyrimidine derivatives TPH104c and TPH104m induce JNK/BNIP3-mediated mitochondrial dysfunction and promotes mitophagy in triple-negative breast cancer (2025)

SSRN Electronic Journal DOI OpenAlex
Updated insights on ASK1 signaling: mechanisms, regulation, and therapeutic potential in diseases (2025)

5 citations DOI OpenAlex