Qiang Fu

High Impact

Assistant Research Professor

University of Arkansas for Medical Sciences

faculty

Internal Med, College of Medicine

25 h-index 62 pubs 2,889 cited

Research Areas

Bone health and treatments Mesenchymal stem cell research Immune Response and Inflammation Diet and metabolism studies MicroRNA in disease regulation Mitochondrial Function and Pathology Gut microbiota and health Musculoskeletal pain and rehabilitation

Links

ORCID Lab Website UAMS TRI Profile

Is this your profile? Verify and claim your profile

OverviewAI-generated summary

Qiang Fu investigates the molecular and cellular mechanisms underlying bone metabolism and diseases, with a particular focus on osteoporosis and related conditions. His research explores the roles of specific molecules, such as long non-coding RNAs (lncRNAs) and microRNAs, in regulating osteoblast proliferation and apoptosis, key processes in bone health. Fu has also studied the impact of certain treatments, like denosumab discontinuation, on bone resorption and the expression of proteins such as osteoprotegerin by osteocytes. His work extends to examining the effects of environmental factors and cellular functions on bone loss, including the role of ionizing radiation on osteoclast mitochondrial function and the consequences of impaired autophagy on bone mass.

Further research by Fu delves into the broader implications of cellular processes and systemic factors on health. This includes investigating the role of short-chain fatty acids in immunity and inflammation within the context of metabolic syndrome and its complications. He has also examined alterations in gut microbiota in patients with immune thrombocytopenia and explored the characteristics of specific muscle groups in relation to orthopedic conditions. Fu's scholarship metrics include an h-index of 25, with 62 total publications and 2,889 citations, designating him as a highly cited researcher. He maintains an active laboratory website.

Metrics

h-index: 25
Publications: 62
Citations: 2,889

Selected Publications

Mechanisms of mitochondrial reactive oxygen species action in bone mesenchymal cells (2025) DOI
Potent suppression of bone remodeling by denosumab does not blunt the anabolic response to romosozumab in mice (2025) DOI
Sirtuin-3 promotes osteoclast maturation and bone loss by regulating mitochondrial ROS production during ionizing radiation exposure (2025) DOI
Mechanisms of mitochondrial reactive oxygen species action in bone mesenchymal cells (2025) DOI
Mitochondrial oxidative stress or decreased autophagy in osteoblast lineage cells is not sufficient to mimic the deleterious effects of aging on bone mechanoresponsiveness (2025) DOI
Refining the identity of mesenchymal cell types associated with murine periosteal and endosteal bone (2024) DOI
A framework for defining mesenchymal cell types associated with murine periosteal and endosteal bone (2023) DOI
Reduced osteoprotegerin expression by osteocytes may contribute to rebound resorption after denosumab discontinuation (2023) DOI
A Rab33b missense mouse model for Smith-McCort dysplasia shows bone resorption defects and altered protein glycosylation (2023) DOI
Loss of chaperone-mediated autophagy is associated with low vertebral cancellous bone mass (2022) DOI
Ionizing Radiation Activates Mitochondrial Function in Osteoclasts and Causes Bone Loss in Young Adult Male Mice (2022) DOI

Grants & Funding

Synergistic Radioprotection of Gastrointestinal Tract by Gamma-Tocotrienol (GT3) and Statins: Efficacy and Mechanisms Uniformed Services University of the Health Sciences - Pass Through: Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. Co-Investigator
Evaluation of IPW-5371, a TGFRI kinase inhibitor, dosed as a single agent or in combination with G-CSF, as a medical countermeasure against the delayed effects of total body irradiation in mice - Continuation NIH/Nat. Inst. of Allergy & Infectious Diseases - Pass Through: Innovation Pathways Principal Investigator
Osteocyte Control of Bone Remodeling NIH/Nat. Inst. of Arthritis & Musculoskeletal & Skin Diseases Principal Investigator
Osteocyte Control of Bone Remodeling NIH/Nat. Inst. of Arthritis & Musculoskeletal & Skin Diseases Co-Investigator
Advanced Development of Gamma-Tocotrienol as a Radiation Countermeasure US Department of Defense - Pass Through: Armed Forces Radiobiology Research Institute Co-Investigator
Center for Musculoskeletal Disease Research (CMDR) NIH/Nat. Inst. of General Medical Sciences Principal Investigator
Endonuclease-targeted radioprotection NIH/Nat. Inst. of Allergy & Infectious Diseases - Pass Through: Duke University Co-Investigator
Center for Musculoskeletal Disease Research (CMDR) NIH/Nat. Inst. of General Medical Sciences Principal Investigator