Huizhong Chen
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Also affiliated: Google (United States) (2020–2023); United States Food and Drug Administration (2004–2026); University of Arizona (1995); Beijing University of Posts and Telecommunications (2015–2016); China Meteorological Administration (2015); Universidade de Brasília (2001); University of Graz (1992); University of Georgia (1993–2003); National University of Defense Technology (2011–2013); Chinese Academy of Sciences (1997–2005); China University of Petroleum, Beijing (2026); Lanzhou University of Technology (2023–2024); Northwest University (2021–2022); Shenyang Center for Disease Control and Prevention (2008); Capital Institute of Pediatrics (2004–2019); Anhui Science and Technology University (2012); Institute of Earth Environment (2004); Children's Hospital of Capital Institute of Pediatrics (2004–2021); State Key Laboratory of Information Photonics and Optical Communications (2015–2016); State Key Laboratory of Loess and Quaternary Geology (2004); Institute of Tropical and Marine Meteorology, China Meteorological Administration (2013–2015); The University of Texas at Austin (2021); Stanford University (2010–2015)
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Huizhong Chen's research centers on the biochemical and molecular characterization of enzymes involved in the metabolism of azo dyes. He has investigated azoreductases from various bacterial species, including *Staphylococcus aureus* and *Enterococcus faecalis*, examining their properties as flavoproteins and their dependence on cofactors like NADPH and FMN. Chen's work also extends to understanding the anaerobic metabolism of specific azo dyes, such as Sudan dyes, by human intestinal microflora. His publications include studies on the degradation of these compounds by prevalent bacteria found in the human gastrointestinal tract.
Beyond his work on azo dye metabolism, Chen has contributed to research in areas such as computer vision and natural language processing, with publications on robust text detection in natural images and semantic attribute descriptions for clothing. He also has a publication related to mobile visual search datasets. His scholarship metrics indicate a significant body of work, with an h-index of 32 and over 4,100 citations across 144 publications.
Metrics
- h-index: 32
- Publications: 143
- Citations: 4,131
Selected Publications
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Evaluating the efficacy of disinfecting products against Bacillus subtilis spore using an optimized method (2026)
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Optimization of sporulation and purification methods for sporicidal efficacy assessment on Bacillus spores (2022)
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Evaluating Cefoperazone-Induced Gut Metabolic Functional Changes in MR1-Deficient Mice (2022)
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Phylogenetically diverse bacteria isolated from tattoo inks, an azo dye-rich environment, decoloize a wide range of azo dyes (2021)
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Phylogenetically diverse bacteria isolated from tattoo inks, an azo dye-rich environment, decolorize a wide range of azo dyes (2021)
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Bile Acid Profile and its Changes in Response to Cefoperazone Treatment in MR1 Deficient Mice (2020)
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Smokeless tobacco impacts oral microbiota in a Syrian Golden hamster cheek pouch carcinogenesis model (2018)
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Mutation network-based understanding of pleiotropic and epistatic mutational behavior of Enterococcus faecalis FMN-dependent azoreductase (2017)
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Evaluation of metabolism of azo dyes and their effects onStaphylococcus aureusmetabolome (2017)
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Effect of smokeless tobacco products on human oral bacteria growth and viability (2016)
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Metabolomics evaluation of the impact of smokeless tobacco exposure on the oral bacterium Capnocytophaga sputigena (2016)
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Differential gene expression inStaphylococcus aureusexposed to Orange II and Sudan III azo dyes (2015)
Collaboration Network
Top Collaborators
- Biochemical and molecular characterization of an azoreductase from Staphylococcus aureus, a tetrameric NADPH-dependent flavoprotein
- Molecular cloning, overexpression, purification, and characterization of an aerobic FMN-dependent azoreductase from Enterococcus faecalis
- Sudan azo dyes and Para Red degradation by prevalent bacteria of the human gastrointestinal tract
- Metabolism of azo dyes by human skin microbiota
- Evaluation of impact of exposure of Sudan azo dyes and their metabolites on human intestinal bacteria
Showing 5 of 23 shared publications
- Evaluation of metabolism of azo dyes and their effects onStaphylococcus aureusmetabolome
- Optimization of sporulation and purification methods for sporicidal efficacy assessment on Bacillus spores
- Effect of smokeless tobacco products on human oral bacteria growth and viability
- Smokeless tobacco impacts oral microbiota in a Syrian Golden hamster cheek pouch carcinogenesis model
- Metabolomics evaluation of the impact of smokeless tobacco exposure on the oral bacterium Capnocytophaga sputigena
Showing 5 of 9 shared publications
- Evaluation of impact of exposure of Sudan azo dyes and their metabolites on human intestinal bacteria
- Identification and molecular characterization of a novel flavin-free NADPH preferred azoreductase encoded by azoB in Pigmentiphaga kullae K24
- Effects of Orange II and Sudan III azo dyes and their metabolites on Staphylococcus aureus
- Effect of smokeless tobacco products on human oral bacteria growth and viability
- Probing the NADH- and Methyl Red-binding site of a FMN-dependent azoreductase (AzoA) from Enterococcus faecalis
Showing 5 of 7 shared publications
- A comparison of conventional methods for the quantification of bacterial cells after exposure to metal oxide nanoparticles
- Evaluation of impact of exposure of Sudan azo dyes and their metabolites on human intestinal bacteria
- SugE, a New Member of the SMR Family of Transporters, Contributes to Antimicrobial Resistance in Enterobacter cloacae
- Detection of benzalkonium chloride resistance in community environmental isolates of staphylococci
- EmmdR, a new member of the MATE family of multidrug transporters, extrudes quinolones from Enterobacter cloacae
Showing 5 of 7 shared publications
- A comparison of conventional methods for the quantification of bacterial cells after exposure to metal oxide nanoparticles
- Evaluation of impact of exposure of Sudan azo dyes and their metabolites on human intestinal bacteria
- Detection of benzalkonium chloride resistance in community environmental isolates of staphylococci
- Effects of Orange II and Sudan III azo dyes and their metabolites on Staphylococcus aureus
- Effect of smokeless tobacco products on human oral bacteria growth and viability
Showing 5 of 6 shared publications
- Identification and molecular characterization of a novel flavin-free NADPH preferred azoreductase encoded by azoB in Pigmentiphaga kullae K24
- Functional role of Trp-105 of Enterococcus faecalis azoreductase (AzoA) as resolved by structural and mutational analysis
- Probing the NADH- and Methyl Red-binding site of a FMN-dependent azoreductase (AzoA) from Enterococcus faecalis
- Identification of the Enzyme Responsible forN-Acetylation of Norfloxacin by Microbacterium sp. Strain 4N2-2
- Mutation network-based understanding of pleiotropic and epistatic mutational behavior of Enterococcus faecalis FMN-dependent azoreductase
- Sudan azo dyes and Para Red degradation by prevalent bacteria of the human gastrointestinal tract
- Decolorization of water and oil-soluble azo dyes by Lactobacillus acidophilus and Lactobacillus fermentum
- Identification and molecular characterization of a novel flavin-free NADPH preferred azoreductase encoded by azoB in Pigmentiphaga kullae K24
- Functional role of Trp-105 of Enterococcus faecalis azoreductase (AzoA) as resolved by structural and mutational analysis
- Probing the NADH- and Methyl Red-binding site of a FMN-dependent azoreductase (AzoA) from Enterococcus faecalis
- Properties of a Recombinant β-Glucosidase from Polycentric Anaerobic Fungus Orpinomyces PC-2 and Its Application for Cellulose Hydrolysis
- Isolation of Extremely AT-Rich Genomic DNA and Analysis of Genes Encoding Carbohydrate-Degrading Enzymes from Orpinomyces sp. Strain PC-2
- High Level Expression and Characterization of the Cyclophilin B Gene from the Anaerobic Fungus Orpinomyces sp. Strain PC-2
- Properties of a Recombinant β-Glucosidase from Polycentric Anaerobic Fungus Orpinomyces PC-2 and Its Application for Cellulose Hydrolysis
- SugE, a New Member of the SMR Family of Transporters, Contributes to Antimicrobial Resistance in Enterobacter cloacae
- Detection of benzalkonium chloride resistance in community environmental isolates of staphylococci
- EmmdR, a new member of the MATE family of multidrug transporters, extrudes quinolones from Enterobacter cloacae
- Impacts of Silver Nanoparticles on Bacterial Multidrug Efflux Pump
- Evaluation of metabolism of azo dyes and their effects onStaphylococcus aureusmetabolome
- Metabolomics evaluation of the impact of smokeless tobacco exposure on the oral bacterium Capnocytophaga sputigena
- Bile Acid Profile and its Changes in Response to Cefoperazone Treatment in MR1 Deficient Mice
- Evaluating Cefoperazone-Induced Gut Metabolic Functional Changes in MR1-Deficient Mice
- Evaluation of metabolism of azo dyes and their effects onStaphylococcus aureusmetabolome
- Metabolomics evaluation of the impact of smokeless tobacco exposure on the oral bacterium Capnocytophaga sputigena
- Bile Acid Profile and its Changes in Response to Cefoperazone Treatment in MR1 Deficient Mice
- Evaluating Cefoperazone-Induced Gut Metabolic Functional Changes in MR1-Deficient Mice
- Metabolism of azo dyes by human skin microbiota
- Differential gene expression inStaphylococcus aureusexposed to Orange II and Sudan III azo dyes
- Azoreductase in Staphylococcus aureus
- Differential gene expression inStaphylococcus aureusexposed to Orange II and Sudan III azo dyes
- Phylogenetically diverse bacteria isolated from tattoo inks, an azo dye-rich environment, decolorize a wide range of azo dyes
- Phylogenetically diverse bacteria isolated from tattoo inks, an azo dye-rich environment, decoloize a wide range of azo dyes
- SugE, a New Member of the SMR Family of Transporters, Contributes to Antimicrobial Resistance in Enterobacter cloacae
- Detection of benzalkonium chloride resistance in community environmental isolates of staphylococci
- EmmdR, a new member of the MATE family of multidrug transporters, extrudes quinolones from Enterobacter cloacae
- Biochemical and molecular characterization of an azoreductase from Staphylococcus aureus, a tetrameric NADPH-dependent flavoprotein
- Crystal structure of an aerobic FMN-dependent azoreductase (AzoA) from Enterococcus faecalis
- Isolation of Extremely AT-Rich Genomic DNA and Analysis of Genes Encoding Carbohydrate-Degrading Enzymes from Orpinomyces sp. Strain PC-2
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