J
Jinshan Jin Data-verified
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Researcher
faculty
13 h-index
24 pubs
360 cited
Research Areas
Links
Biography and Research Information
OverviewAI-generated summary
Jinshan Jin's research focuses on the design, synthesis, and biological evaluation of novel SecA inhibitors. SecA is a key protein involved in bacterial protein translocation, and inhibiting its function can attenuate virulence and act as an antimicrobial strategy. Jin has published work detailing the development of pyrimidine analogs and thiouracil derivatives as SecA inhibitors, investigating their effectiveness against pathogens like Methicillin-resistant *Staphylococcus aureus* (MRSA) and *Bacillus anthracis*. Some of this research explores how these inhibitors can bypass bacterial efflux pumps, a common mechanism of antibiotic resistance. Additionally, Jin has investigated the optimization of sporulation and purification methods for assessing sporicidal efficacy and studied the dye-decolorizing capabilities of bacteria isolated from tattoo inks, an environment rich in azo dyes. Jin's scholarship metrics include an h-index of 13, with 24 total publications and 356 total citations.
Metrics
- h-index: 13
- Publications: 24
- Citations: 360
Selected Publications
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Optimization of sporulation and purification methods for sporicidal efficacy assessment on <i>Bacillus</i> spores (2022)
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Phylogenetically diverse bacteria isolated from tattoo inks, an azo dye-rich environment, decoloize a wide range of azo dyes (2021)
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Thiouracil SecA inhibitors: bypassing the effects of efflux pumps and attenuating virulence factor secretion in MRSA and Bacillus anthracis (2021)
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Phylogenetically diverse bacteria isolated from tattoo inks, an azo dye-rich environment, decolorize a wide range of azo dyes (2021)
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Design, synthesis, and biological evaluation of pyrimidine analogs as SecA inhibitors (2021)
Collaboration Network
Top Collaborators
Binghe Wang
Georgia State University (US)
4 shared publications
- Design, synthesis, and biological evaluation of pyrimidine analogs as SecA inhibitors
- Thiouracil SecA inhibitors: bypassing the effects of efflux pumps and attenuating virulence factor secretion in MRSA and Bacillus anthracis
- Evaluation of the Seca Inhibitors as Novel Anti-Microbial Agents
- Design, Synthesis and Biological Evaluation of Pyrimidine Analogues as&nbsp;SecA Inhibitors
Phang C. Tai
Georgia State University (US)
4 shared publications
- Design, synthesis, and biological evaluation of pyrimidine analogs as SecA inhibitors
- Thiouracil SecA inhibitors: bypassing the effects of efflux pumps and attenuating virulence factor secretion in MRSA and Bacillus anthracis
- Evaluation of the Seca Inhibitors as Novel Anti-Microbial Agents
- Design, Synthesis and Biological Evaluation of Pyrimidine Analogues as&nbsp;SecA Inhibitors
Fanté Bamba
Université Félix Houphouët-Boigny (CI)
3 shared publications
- Design, synthesis, and biological evaluation of pyrimidine analogs as SecA inhibitors
- Thiouracil SecA inhibitors: bypassing the effects of efflux pumps and attenuating virulence factor secretion in MRSA and Bacillus anthracis
- Design, Synthesis and Biological Evaluation of Pyrimidine Analogues as&nbsp;SecA Inhibitors
Arpana S. Chaudhary
Bayer (United States) (US)
3 shared publications
- Design, synthesis, and biological evaluation of pyrimidine analogs as SecA inhibitors
- Thiouracil SecA inhibitors: bypassing the effects of efflux pumps and attenuating virulence factor secretion in MRSA and Bacillus anthracis
- Design, Synthesis and Biological Evaluation of Pyrimidine Analogues as&nbsp;SecA Inhibitors
Huizhong Chen
National Center for Toxicological Research (US)
3 shared publications
- Optimization of sporulation and purification methods for sporicidal efficacy assessment on <i>Bacillus</i> spores
- Phylogenetically diverse bacteria isolated from tattoo inks, an azo dye-rich environment, decolorize a wide range of azo dyes
- Phylogenetically diverse bacteria isolated from tattoo inks, an azo dye-rich environment, decoloize a wide range of azo dyes
Seong Won Nho
National Center for Toxicological Research (US)
2 shared publications
- Phylogenetically diverse bacteria isolated from tattoo inks, an azo dye-rich environment, decolorize a wide range of azo dyes
- Phylogenetically diverse bacteria isolated from tattoo inks, an azo dye-rich environment, decoloize a wide range of azo dyes
Ohgew Kweon
National Center for Toxicological Research
2 shared publications
In database
- Phylogenetically diverse bacteria isolated from tattoo inks, an azo dye-rich environment, decolorize a wide range of azo dyes
- Phylogenetically diverse bacteria isolated from tattoo inks, an azo dye-rich environment, decoloize a wide range of azo dyes
Seong‐Jae Kim
National Center for Toxicological Research
2 shared publications
In database
- Phylogenetically diverse bacteria isolated from tattoo inks, an azo dye-rich environment, decolorize a wide range of azo dyes
- Phylogenetically diverse bacteria isolated from tattoo inks, an azo dye-rich environment, decoloize a wide range of azo dyes
Carl E. Cerniglia
National Center for Toxicological Research
2 shared publications
In database
- Phylogenetically diverse bacteria isolated from tattoo inks, an azo dye-rich environment, decolorize a wide range of azo dyes
- Phylogenetically diverse bacteria isolated from tattoo inks, an azo dye-rich environment, decoloize a wide range of azo dyes
Christina Cerovsky
Georgia State University (US)
1 shared publication
- Evaluation of the Seca Inhibitors as Novel Anti-Microbial Agents
Hsiuchin Yang
Georgia State University (US)
1 shared publication
- Evaluation of the Seca Inhibitors as Novel Anti-Microbial Agents
Xuewen Cui
United States Food and Drug Administration
1 shared publication
In database
- Phylogenetically diverse bacteria isolated from tattoo inks, an azo dye-rich environment, decolorize a wide range of azo dyes
Mi Sun Moon
Center for Food Safety and Applied Nutrition (US)
1 shared publication
- Phylogenetically diverse bacteria isolated from tattoo inks, an azo dye-rich environment, decolorize a wide range of azo dyes
Ying‐Hsin Hsieh
Georgia State University (US)
1 shared publication
- Thiouracil SecA inhibitors: bypassing the effects of efflux pumps and attenuating virulence factor secretion in MRSA and Bacillus anthracis
Xue Wen Cui
1 shared publication
- Phylogenetically diverse bacteria isolated from tattoo inks, an azo dye-rich environment, decoloize a wide range of azo dyes
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