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Listed
Presence
Current · Arkansas
Last published
2026
Sources
OpenAlex · ORCID
Refreshed
2026-08-06
H
Hari B. Krishnan
Research Molecular Biologist
Faculty Researcher
55 h-index
284 pubs
9,221 cited
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Hari B. Krishnan's research focuses on molecular biology, with a particular emphasis on plant proteins, genetics, and their applications. His work investigates methods to enhance the nutritional content of soybeans, including increasing protein and sulfur amino acid levels. He has explored the utilization of byproducts from tofu processing, such as wastewater, as a source for bioactive peptides like lunasin. Krishnan has also studied the ice recrystallization inhibition activity of soy protein hydrolysates and the potential of other plant-based protein resources, such as Adenanthera pavonina, examining their seed protein composition and the localization of trypsin inhibitors.
Further research by Krishnan delves into the genetic mechanisms of plant development, including the hypermethylation of miRNA genes during nodule development in soybeans. He has also investigated protein inhibitors, such as Bowman-Birk inhibitors, and their activities, employing techniques like CRISPR-Cas9 to generate mutants and study their effects on trypsin and chymotrypsin inhibitor levels. His work has also addressed practical applications, such as developing cost-effective procedures for measuring trypsin inhibitor activity in soy products and exploring the anti-inflammatory properties of lunasin concentrates in models of ulcerative colitis.
Metrics
- h-index: 55
- Publications: 284
- Citations: 9,221
Selected Publications
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Single-nucleus RNA-sequencing reveals the cellular programs driving nematode-induced giant cell formation in tomato (2025)
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13. Evaluation of soybean-derived trypsin inhibitor proteins on gastric emptying, luminal pH, and endogenous enzyme activity in late-stage nursery pigs (2025)
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Increasing dietary soybean-derived trypsin inhibitor protein compromises nursery pig performance, nitrogen digestibility, and retention (2025)
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Increasing trypsin inhibitor concentrations in growing pig diets compromises growth performance and protein digestibility (2025)
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Seed-Specific Silencing of Abundantly Expressed Soybean Bowman–Birk Protease Inhibitor Genes by RNAi Lowers Trypsin and Chymotrypsin Inhibitor Activities and Enhances Protein Digestibility (2025)
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Increasing dietary soybean trypsin inhibitor protein attenuates nursery pig performance (2025)
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Identification of an ice recrystallization inhibiting albumin protein from wheat flour and insights from molecular dynamics simulation (2025)
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Isolation and characterization of ice recrystallization inhibitory molecules from black soldier fly larvae (2025)
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Genomic and biochemical comparison of allelic triple‐mutant lines derived from conventional breeding and multiplex gene editing (2025)
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Enzymatic hydrolysis altered the physicochemical and immunogenic profile of protein-based ingredients derived from industrial hempseed (Cannabis sativa L.) (2025)
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14 The impact of soybean derived trypsin inhibitor concentrations on growth performance, health, and variability of nursery pigs (2025)
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Supplementation of multienzyme with acidifier alleviates the antinutritional effects of a high soybean meal diet for nursery pigs (2025)
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High-Resolution Mass Spectrometry Approach for Proteomic and Metabolomic Analyses of High-Protein Soybean Seeds (2025)
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Effects of feeding expeller-extruded high oleic soybeans in broiler diets on growth performance, blood profile, and meat quality (2025)
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Laboratory assays do not consistently indicate under processing of soybean meal that negatively impacts broiler performance (2025)
Collaboration Network
Top Collaborators
Won‐Seok Kim
University of Missouri (US)
10 shared publications
- Utilization of tofu processing wastewater as a source of the bioactive peptide lunasin
- Title: Hypermethylation of miRNA Genes During Nodule Development
- Bowman–Birk Inhibitor Mutants of Soybean Generated by CRISPR-Cas9 Reveal Drastic Reductions in Trypsin and Chymotrypsin Inhibitor Activities
- Elemental sulfur concentration can be used as a rapid, reliable, and cost-effective predictor of sulfur amino acid content of soybean seeds
- Genomic and biochemical comparison of allelic triple‐mutant lines derived from conventional breeding and multiplex gene editing
Showing 5 of 10 shared publications
Sun‐Hyung Kim
University of Missouri (US)
9 shared publications
- A fast and cost-effective procedure for reliable measurement of trypsin inhibitor activity in soy and soy products
- Adenanthera pavonina, a potential plant-based protein resource: Seed protein composition and immunohistochemical localization of trypsin inhibitors
- Bowman–Birk Inhibitor Mutants of Soybean Generated by CRISPR-Cas9 Reveal Drastic Reductions in Trypsin and Chymotrypsin Inhibitor Activities
- Elemental sulfur concentration can be used as a rapid, reliable, and cost-effective predictor of sulfur amino acid content of soybean seeds
- Soybean seed proteomics: Methods for the isolation, detection, and identification of low abundance proteins
Showing 5 of 9 shared publications
Vermont P. Día
University of Tennessee at Knoxville (US)
7 shared publications
- Utilization of tofu processing wastewater as a source of the bioactive peptide lunasin
- Ice Recrystallization Inhibition Activity of Soy Protein Hydrolysates
- Lunasin protease inhibitor concentrate decreases pro-inflammatory cytokines and improves histopathological markers in dextran sodium sulfate-induced ulcerative colitis
- Glycosylated peptides isolated from cheese whey have antifreezing activity
- Isolation and characterization of ice recrystallization inhibitory molecules from black soldier fly larvae
Showing 5 of 7 shared publications
Nicholas K Gabler
Iowa State University (US)
7 shared publications
- 137 Impact of dietary soybean-mediated trypsin inhibitor concentrations on nursery pig performance
- 246 The effect of trypsin inhibitor unit concentrations from raw soybeans in grower pig performance and protein digestibility
- Increasing dietary soybean-derived trypsin inhibitor protein compromises nursery pig performance, nitrogen digestibility, and retention
- 14 The impact of soybean derived trypsin inhibitor concentrations on growth performance, health, and variability of nursery pigs
- Increasing dietary soybean trypsin inhibitor protein attenuates nursery pig performance
Showing 5 of 7 shared publications
Kayla A Miller
Iowa State University (US)
6 shared publications
- 137 Impact of dietary soybean-mediated trypsin inhibitor concentrations on nursery pig performance
- 246 The effect of trypsin inhibitor unit concentrations from raw soybeans in grower pig performance and protein digestibility
- Increasing dietary soybean-derived trypsin inhibitor protein compromises nursery pig performance, nitrogen digestibility, and retention
- 14 The impact of soybean derived trypsin inhibitor concentrations on growth performance, health, and variability of nursery pigs
- Increasing dietary soybean trypsin inhibitor protein attenuates nursery pig performance
Showing 5 of 6 shared publications
Omarh F Mendoza
Carle Foundation Hospital (US)
6 shared publications
- 137 Impact of dietary soybean-mediated trypsin inhibitor concentrations on nursery pig performance
- 246 The effect of trypsin inhibitor unit concentrations from raw soybeans in grower pig performance and protein digestibility
- Increasing dietary soybean-derived trypsin inhibitor protein compromises nursery pig performance, nitrogen digestibility, and retention
- 14 The impact of soybean derived trypsin inhibitor concentrations on growth performance, health, and variability of nursery pigs
- Increasing dietary soybean trypsin inhibitor protein attenuates nursery pig performance
Showing 5 of 6 shared publications
Joel D Spencer
United Animal Health (United States) (US)
6 shared publications
- 137 Impact of dietary soybean-mediated trypsin inhibitor concentrations on nursery pig performance
- 246 The effect of trypsin inhibitor unit concentrations from raw soybeans in grower pig performance and protein digestibility
- Increasing dietary soybean-derived trypsin inhibitor protein compromises nursery pig performance, nitrogen digestibility, and retention
- 14 The impact of soybean derived trypsin inhibitor concentrations on growth performance, health, and variability of nursery pigs
- Increasing dietary soybean trypsin inhibitor protein attenuates nursery pig performance
Showing 5 of 6 shared publications
Savithiry Natarajan
Beltsville Agricultural Research Center (US)
5 shared publications
- Quantitative proteomic analyses reveal the dynamics of protein and amino acid accumulation during soybean seed development
- Protein profiling of fast neutron soybean mutant seeds reveals differential accumulation of seed and iron storage proteins
- Metabolic Profiling of a Fast Neutron Soybean Mutant Reveals an Increased Abundance of Isoflavones
- Metabolite profiling of a high protein fast neutron soybean mutant revealed increased storage of methionine and flavonoids
- Non‐targeted metabolite profiling of a fast neutron soybean mutant reveals an increase in sulfur‐containing metabolites
Tong Wang
University of Tennessee at Knoxville (US)
5 shared publications
- Ice Recrystallization Inhibition Activity of Soy Protein Hydrolysates
- Glycosylated peptides isolated from cheese whey have antifreezing activity
- Isolation and characterization of ice recrystallization inhibitory molecules from black soldier fly larvae
- Identification of an ice recrystallization inhibiting albumin protein from wheat flour and insights from molecular dynamics simulation
- Hydrolysates from Sorghum Crude Kafirin Extract Exhibit Ice Recrystallization Inhibition Activity
Mitchell J Nisley
Iowa State University (US)
5 shared publications
- 137 Impact of dietary soybean-mediated trypsin inhibitor concentrations on nursery pig performance
- 246 The effect of trypsin inhibitor unit concentrations from raw soybeans in grower pig performance and protein digestibility
- Increasing dietary soybean-derived trypsin inhibitor protein compromises nursery pig performance, nitrogen digestibility, and retention
- Increasing trypsin inhibitor concentrations in growing pig diets compromises growth performance and protein digestibility
- 13. Evaluation of soybean-derived trypsin inhibitor proteins on gastric emptying, luminal pH, and endogenous enzyme activity in late-stage nursery pigs
Bo Song
Harbin Normal University (CN)
4 shared publications
- Development of soybean experimental lines with enhanced protein and sulfur amino acid content
- Generation of New β-Conglycinin-Deficient Soybean Lines by Editing the lincRNA <i>lincCG1</i> Using the CRISPR/Cas9 System
- Breeding of ‘DND358’: A new soybean cultivar for processing soy protein isolate with a hypocholesterolemic effect similar to that of fenofibrate
- Hypocholesterolemic effects of soy protein isolates from soybeans differing in 7S and 11S globulin subunits vary in rats fed a high cholesterol diet
Tarek Hewezi
University of Tennessee at Knoxville (US)
4 shared publications
- Title: Hypermethylation of miRNA Genes During Nodule Development
- Soybean gene co‐expression network analysis identifies two co‐regulated gene modules associated with nodule formation and development
- Differential symbiotic compatibilities between rhizobium strains and cultivated and wild soybeans revealed by anatomical and transcriptome analyses
- Single-nucleus RNA-sequencing reveals the cellular programs driving nematode-induced giant cell formation in tomato
Nazrul Islam
Genomics (United Kingdom) (GB)
3 shared publications
- Quantitative proteomic analyses reveal the dynamics of protein and amino acid accumulation during soybean seed development
- Protein profiling of fast neutron soybean mutant seeds reveals differential accumulation of seed and iron storage proteins
- High-Resolution Mass Spectrometry Approach for Proteomic and Metabolomic Analyses of High-Protein Soybean Seeds
Zhendong Qiu
Northeast Agricultural University (CN)
3 shared publications
- Generation of New β-Conglycinin-Deficient Soybean Lines by Editing the lincRNA <i>lincCG1</i> Using the CRISPR/Cas9 System
- Breeding of ‘DND358’: A new soybean cultivar for processing soy protein isolate with a hypocholesterolemic effect similar to that of fenofibrate
- Hypocholesterolemic effects of soy protein isolates from soybeans differing in 7S and 11S globulin subunits vary in rats fed a high cholesterol diet
Shuzhen Zhang
Northeast Agricultural University (CN)
3 shared publications
- Generation of New β-Conglycinin-Deficient Soybean Lines by Editing the lincRNA <i>lincCG1</i> Using the CRISPR/Cas9 System
- Breeding of ‘DND358’: A new soybean cultivar for processing soy protein isolate with a hypocholesterolemic effect similar to that of fenofibrate
- Hypocholesterolemic effects of soy protein isolates from soybeans differing in 7S and 11S globulin subunits vary in rats fed a high cholesterol diet
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