Biography and Research Information
OverviewAI-generated summary
Shayu Deshpande's research investigates the evolutionary pathways and molecular mechanisms underlying multiple myeloma, a hematologic malignancy. Their work has characterized the progression of multiple myeloma from smoldering states to relapse-refractory disease, utilizing single-cell analysis to examine the role of the immune microenvironment. Deshpande is also engaged in public health research focused on improving access to healthcare for children in rural areas. This includes the development and study of school-based enhanced hearing screening programs combined with specialty telehealth follow-up, with protocols for trials in rural Alaska and Kentucky. These initiatives aim to address health disparities by leveraging technology to connect underserved children with necessary medical care. Deshpande has published 46 papers, accumulating over 1,050 citations and an h-index of 15.
Metrics
- h-index: 15
- Publications: 46
- Citations: 1,095
Positions
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Associate Staff Scientist publications 2015–2025University of Arkansas for Medical Sciences Institution web page
Selected Publications
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Transforming Access to Hearing Care: Community Perspectives on School-Based Telehealth in Rural Appalachia (2025)
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Improving Access to Specialty Care for Rural Children Using Enhanced Hearing Screening and Specialty Telehealth Follow-Up in Rural Kentucky Schools: Protocol for a Hybrid Effectiveness-Implementation Stepped Wedge, Cluster-Randomized Controlled Trial (Appalachian STAR Trial) (2025)
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School-based enhanced hearing screening and specialty telehealth follow-up for hearing loss among children in rural Alaska: study protocol for a hybrid effectiveness-implementation stepped wedge, cluster-randomized controlled trial (North STAR trial) (2025)
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School-Based Enhanced Hearing Screening and Specialty Telehealth Follow-Up for Hearing Loss Among Children in Rural Alaska: Study Protocol for a Hybrid Effectiveness-Implementation Stepped Wedge, Cluster-Randomized Controlled Trial (North STAR Trial) (2025)
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Characterizing the role of the immune microenvironment in multiple myeloma progression at a single-cell level (2022)
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The spatio-temporal evolution of multiple myeloma from baseline to relapse-refractory states (2022)
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Interaction of the Class A Scavenger Receptor with Multiple Myeloma Cells (2022)
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The Spatio-Temporal Evolution of Multiple Myeloma from Baseline to Relapse-Refractory States (2022)
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The molecular make up of smoldering myeloma highlights the evolutionary pathways leading to multiple myeloma (2021)
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Additional file 2 of The functional epigenetic landscape of aberrant gene expression in molecular subgroups of newly diagnosed multiple myeloma (2020)
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The functional epigenetic landscape of aberrant gene expression in molecular subgroups of newly diagnosed multiple myeloma (2020)
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Monitoring treatment response and disease progression in myeloma with circulating cell‐free DNA (2020)
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The functional epigenetic landscape of aberrant gene expression in molecular subgroups of newly diagnosed multiple myeloma (2020)
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Genomic analysis of primary plasma cell leukemia reveals complex structural alterations and high-risk mutational patterns (2020)
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Analysis of the Sub-Clonal Structure of Smoldering Myeloma over Time Provides a New Means of Disease Monitoring and Highlights Evolutionary Trajectories Leading to Myeloma (2019)
Collaboration Network
Top Collaborators
- Clonal selection and double-hit events involving tumor suppressor genes underlie relapse in myeloma
- The molecular make up of smoldering myeloma highlights the evolutionary pathways leading to multiple myeloma
- The spatio-temporal evolution of multiple myeloma from baseline to relapse-refractory states
- Loss of heterozygosity as a marker of homologous repair deficiency in multiple myeloma: a role for PARP inhibition?
- Microhomology-mediated end joining drives complex rearrangements and overexpression of MYC and PVT1 in multiple myeloma
Showing 5 of 26 shared publications
- Clonal selection and double-hit events involving tumor suppressor genes underlie relapse in myeloma
- The molecular make up of smoldering myeloma highlights the evolutionary pathways leading to multiple myeloma
- The spatio-temporal evolution of multiple myeloma from baseline to relapse-refractory states
- Loss of heterozygosity as a marker of homologous repair deficiency in multiple myeloma: a role for PARP inhibition?
- Microhomology-mediated end joining drives complex rearrangements and overexpression of MYC and PVT1 in multiple myeloma
Showing 5 of 26 shared publications
- Clonal selection and double-hit events involving tumor suppressor genes underlie relapse in myeloma
- The molecular make up of smoldering myeloma highlights the evolutionary pathways leading to multiple myeloma
- Loss of heterozygosity as a marker of homologous repair deficiency in multiple myeloma: a role for PARP inhibition?
- Microhomology-mediated end joining drives complex rearrangements and overexpression of MYC and PVT1 in multiple myeloma
- The functional epigenetic landscape of aberrant gene expression in molecular subgroups of newly diagnosed multiple myeloma
Showing 5 of 23 shared publications
- Clonal selection and double-hit events involving tumor suppressor genes underlie relapse in myeloma
- The molecular make up of smoldering myeloma highlights the evolutionary pathways leading to multiple myeloma
- The spatio-temporal evolution of multiple myeloma from baseline to relapse-refractory states
- Characterizing the role of the immune microenvironment in multiple myeloma progression at a single-cell level
- Genomic analysis of primary plasma cell leukemia reveals complex structural alterations and high-risk mutational patterns
Showing 5 of 23 shared publications
- Clonal selection and double-hit events involving tumor suppressor genes underlie relapse in myeloma
- The molecular make up of smoldering myeloma highlights the evolutionary pathways leading to multiple myeloma
- The spatio-temporal evolution of multiple myeloma from baseline to relapse-refractory states
- Loss of heterozygosity as a marker of homologous repair deficiency in multiple myeloma: a role for PARP inhibition?
- Microhomology-mediated end joining drives complex rearrangements and overexpression of MYC and PVT1 in multiple myeloma
Showing 5 of 23 shared publications
- Clonal selection and double-hit events involving tumor suppressor genes underlie relapse in myeloma
- The molecular make up of smoldering myeloma highlights the evolutionary pathways leading to multiple myeloma
- The spatio-temporal evolution of multiple myeloma from baseline to relapse-refractory states
- Characterizing the role of the immune microenvironment in multiple myeloma progression at a single-cell level
- Genomic analysis of primary plasma cell leukemia reveals complex structural alterations and high-risk mutational patterns
Showing 5 of 22 shared publications
- Clonal selection and double-hit events involving tumor suppressor genes underlie relapse in myeloma
- The molecular make up of smoldering myeloma highlights the evolutionary pathways leading to multiple myeloma
- The spatio-temporal evolution of multiple myeloma from baseline to relapse-refractory states
- Characterizing the role of the immune microenvironment in multiple myeloma progression at a single-cell level
- Genomic analysis of primary plasma cell leukemia reveals complex structural alterations and high-risk mutational patterns
Showing 5 of 22 shared publications
- Clonal selection and double-hit events involving tumor suppressor genes underlie relapse in myeloma
- The molecular make up of smoldering myeloma highlights the evolutionary pathways leading to multiple myeloma
- The spatio-temporal evolution of multiple myeloma from baseline to relapse-refractory states
- Loss of heterozygosity as a marker of homologous repair deficiency in multiple myeloma: a role for PARP inhibition?
- Microhomology-mediated end joining drives complex rearrangements and overexpression of MYC and PVT1 in multiple myeloma
Showing 5 of 22 shared publications
- Clonal selection and double-hit events involving tumor suppressor genes underlie relapse in myeloma
- The molecular make up of smoldering myeloma highlights the evolutionary pathways leading to multiple myeloma
- The spatio-temporal evolution of multiple myeloma from baseline to relapse-refractory states
- Characterizing the role of the immune microenvironment in multiple myeloma progression at a single-cell level
- Genomic analysis of primary plasma cell leukemia reveals complex structural alterations and high-risk mutational patterns
Showing 5 of 21 shared publications
- Clonal selection and double-hit events involving tumor suppressor genes underlie relapse in myeloma
- The molecular make up of smoldering myeloma highlights the evolutionary pathways leading to multiple myeloma
- The spatio-temporal evolution of multiple myeloma from baseline to relapse-refractory states
- Microhomology-mediated end joining drives complex rearrangements and overexpression of MYC and PVT1 in multiple myeloma
- Characterizing the role of the immune microenvironment in multiple myeloma progression at a single-cell level
Showing 5 of 19 shared publications
- Clonal selection and double-hit events involving tumor suppressor genes underlie relapse in myeloma
- The molecular make up of smoldering myeloma highlights the evolutionary pathways leading to multiple myeloma
- The spatio-temporal evolution of multiple myeloma from baseline to relapse-refractory states
- Genomic analysis of primary plasma cell leukemia reveals complex structural alterations and high-risk mutational patterns
- The prognostic value of the depth of response in multiple myeloma depends on the time of assessment, risk status and molecular subtype
Showing 5 of 13 shared publications
- Clonal selection and double-hit events involving tumor suppressor genes underlie relapse in myeloma
- The spatio-temporal evolution of multiple myeloma from baseline to relapse-refractory states
- Characterizing the role of the immune microenvironment in multiple myeloma progression at a single-cell level
- Kinase domain activation through gene rearrangement in multiple myeloma
- Impact of Minimal Residual Disease in High and Standard Risk Multiple Myeloma
Showing 5 of 12 shared publications
- Clonal selection and double-hit events involving tumor suppressor genes underlie relapse in myeloma
- The prognostic value of the depth of response in multiple myeloma depends on the time of assessment, risk status and molecular subtype
- Kinase domain activation through gene rearrangement in multiple myeloma
- Impact of Minimal Residual Disease in High and Standard Risk Multiple Myeloma
- Extensive Regional Intra-Clonal Heterogeneity in Multiple Myeloma - Implications for Diagnostics, Risk Stratification and Targeted Treatment
Showing 5 of 11 shared publications
- Clonal selection and double-hit events involving tumor suppressor genes underlie relapse in myeloma
- The spatio-temporal evolution of multiple myeloma from baseline to relapse-refractory states
- Characterizing the role of the immune microenvironment in multiple myeloma progression at a single-cell level
- The prognostic value of the depth of response in multiple myeloma depends on the time of assessment, risk status and molecular subtype
- Kinase domain activation through gene rearrangement in multiple myeloma
Showing 5 of 11 shared publications
- The molecular make up of smoldering myeloma highlights the evolutionary pathways leading to multiple myeloma
- Microhomology-mediated end joining drives complex rearrangements and overexpression of MYC and PVT1 in multiple myeloma
- Genomic analysis of primary plasma cell leukemia reveals complex structural alterations and high-risk mutational patterns
- MYC Rearrangements in Multiple Myeloma Are Complex, Can Involve More Than Five Different Chromosomes, and Correlate with Increased Expression of MYC and a Distinct Downstream Gene Expression Pattern
- Analysis of the Sub-Clonal Structure of Smoldering Myeloma over Time Provides a New Means of Disease Monitoring and Highlights Evolutionary Trajectories Leading to Myeloma
Showing 5 of 10 shared publications
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