Guo-Lei Zhou

This is a likely match — the affiliation was inferred from OpenAlex, ORCID, and web sources but has not been fully confirmed. Treat with appropriate caution.

Researcher

Arkansas State University

Also affiliated: Howard Hughes Medical Institute (2006); Shimane University (1998–2015); University of Michigan (2016); China International Science and Technology Cooperation (2023); VA Ann Arbor Healthcare System (2016); New York Institute of Technology (2023); Michigan United (2016); Gansu Provincial Hospital (2023); Arkansas Biosciences Institute (2019); University of Pennsylvania (2003–2010)

Faculty Researcher

15 h-index 29 pubs 938 cited

Research Areas

Biomedical Subjects

Links

Lab Website

OverviewAI-generated summary

Guo-Lei Zhou's research focuses on the molecular mechanisms underlying cellular processes, particularly in the context of cancer biology and neural stem cell differentiation. He investigates the role of specific proteins, such as CAP1 (cyclase-associated protein 1), in mediating signaling pathways that influence cell behavior, including matrix adhesion in colon cancer cells and gene expression in lung adenocarcinoma. Zhou has also explored the use of biomaterials, such as gold nanorods, to promote the differentiation of rat fetal neural stem cells into oligodendrocytes. His work involves studying signal transduction, phosphorylation, and cytoskeletal protein function. Zhou has published 29 papers, with a total of 928 citations and an h-index of 15. He has collaborated with several researchers at Arkansas State University, including Jennifer Y. Xie and Krishna Deo Sharma.

Metrics

h-index: 15
Publications: 29
Citations: 938

Selected Publications

CAP1 (cyclase-associated protein 1) mediates the cyclic AMP signals that activate Rap1 in stimulating matrix adhesion of colon cancer cells (2023)

Cellular Signalling 15 citations DOI OpenAlex
Gold Nanorod Substrate for Rat Fetal Neural Stem Cell Differentiation into Oligodendrocytes (2022)

Nanomaterials 7 citations DOI OpenAlex
Dynamic Phosphorylation and Dephosphorylation of CAP1 (Cyclase‐Associated Protein 1) by Antagonistic Signaling through CDK5 and cAMP are Critical for the Protein Functions in Actin Filament Disassembly and Cell Adhesion (2020)

The FASEB Journal DOI OpenAlex
Dynamic Phosphorylation and Dephosphorylation of Cyclase-Associated Protein 1 by Antagonistic Signaling through Cyclin-Dependent Kinase 5 and cAMP Are Critical for the Protein Functions in Actin Filament Disassembly and Cell Adhesion (2019)

Molecular and Cellular Biology 12 citations DOI OpenAlex
The Cytoskeletal Protein Cyclase-Associated Protein 1 (CAP1) in Breast Cancer: Context-Dependent Roles in Both the Invasiveness and Proliferation of Cancer Cells and Underlying Cell Signals (2019)

International Journal of Molecular Sciences 28 citations DOI OpenAlex
Phosphorylation Regulates CAP1 (Cyclase-Associated Protein 1) Functions in the Motility and Invasion of Pancreatic Cancer Cells (2019)

Scientific Reports 18 citations DOI OpenAlex
CDK5 Functions as a Tumor Promoter in Human Lung Cancer (2018)

Journal of Cancer 28 citations DOI OpenAlex
Phosphorylation of the Cytoskeletal Protein CAP1 Regulates Non-Small Cell Lung Cancer Survival and Proliferation by GSK3β (2018)

Journal of Cancer 9 citations DOI OpenAlex
CAP1 (Cyclase-Associated Protein 1) Exerts Distinct Functions in the Proliferation and Metastatic Potential of Breast Cancer Cells Mediated by ERK (2016)

Scientific Reports 31 citations DOI OpenAlex
Phosphorylation of the cytoskeletal protein CAP1 controls its association with cofilin and actin (2014)

Journal of Cell Science 42 citations DOI OpenAlex
Mammalian CAP (Cyclase-associated protein) in the world of cell migration (2013)

Cell Adhesion & Migration 26 citations DOI OpenAlex
Mammalian Adenylyl Cyclase-associated Protein 1 (CAP1) Regulates Cofilin Function, the Actin Cytoskeleton, and Cell Adhesion (2013)

Journal of Biological Chemistry 92 citations DOI OpenAlex