Guo-Lei Zhou

This is a likely match — the affiliation was inferred from OpenAlex, ORCID, and web sources but has not been fully confirmed. Treat with appropriate caution.

Professor of Cell Biology

Arkansas State University

Also affiliated: Howard Hughes Medical Institute (2006); Shimane University (1998–2015); University of Michigan (2016); University of Shimane (2000); VA Ann Arbor Healthcare System (2016); New York Institute of Technology (2023); Ann Arbor VA Medical Center (2016); Department of Biological Sciences (2013); University of Pennsylvania (2003–2010)

15 h-index 28 pubs 923 cited

Research Areas

Biomedical Subjects

Links

Lab Website

OverviewAI-generated summary

Guo-Lei Zhou's research investigates the molecular mechanisms governing cell migration, cytoskeletal dynamics, and signal transduction pathways. His work has focused on the roles of proteins such as Pak1, CAP1, and cofilin in cellular processes. Zhou has examined how phosphorylation events, including those mediated by Akt and c-Abl, influence protein interactions and downstream signaling that affects cell movement and adhesion. His publications also explore the involvement of these proteins in apoptosis and the metastatic potential of cancer cells, particularly breast cancer. Collaborations within Arkansas State University include shared publications with Jennifer Y. Xie, Krishna Deo Sharma, Auburn Ramsey, and Jianfeng Xu. Zhou has an h-index of 16 and has authored 29 publications with a total of 945 citations.

Metrics

h-index: 15
Publications: 28
Citations: 923

Positions

Professor of Cell Biology publications 2013–2023

Arkansas State University Institution web page

Selected Publications

CAP1 (cyclase-associated protein 1) mediates the cyclic AMP signals that activate Rap1 in stimulating matrix adhesion of colon cancer cells (2023)

Cellular Signalling 16 citations DOI OpenAlex
Gold Nanorod Substrate for Rat Fetal Neural Stem Cell Differentiation into Oligodendrocytes (2022)

Nanomaterials 7 citations DOI OpenAlex
Dynamic Phosphorylation and Dephosphorylation of CAP1 (Cyclase‐Associated Protein 1) by Antagonistic Signaling through CDK5 and cAMP are Critical for the Protein Functions in Actin Filament Disassembly and Cell Adhesion (2020)

The FASEB Journal DOI OpenAlex
Dynamic Phosphorylation and Dephosphorylation of Cyclase-Associated Protein 1 by Antagonistic Signaling through Cyclin-Dependent Kinase 5 and cAMP Are Critical for the Protein Functions in Actin Filament Disassembly and Cell Adhesion (2019)

Molecular and Cellular Biology 12 citations DOI OpenAlex
The Cytoskeletal Protein Cyclase-Associated Protein 1 (CAP1) in Breast Cancer: Context-Dependent Roles in Both the Invasiveness and Proliferation of Cancer Cells and Underlying Cell Signals (2019)

International Journal of Molecular Sciences 28 citations DOI OpenAlex
Phosphorylation Regulates CAP1 (Cyclase-Associated Protein 1) Functions in the Motility and Invasion of Pancreatic Cancer Cells (2019)

Scientific Reports 18 citations DOI OpenAlex
CDK5 Functions as a Tumor Promoter in Human Lung Cancer (2018)

Journal of Cancer 28 citations DOI OpenAlex
Phosphorylation of the Cytoskeletal Protein CAP1 Regulates Non-Small Cell Lung Cancer Survival and Proliferation by GSK3β (2018)

Journal of Cancer 9 citations DOI OpenAlex
CAP1 (Cyclase-Associated Protein 1) Exerts Distinct Functions in the Proliferation and Metastatic Potential of Breast Cancer Cells Mediated by ERK (2016)

Scientific Reports 31 citations DOI OpenAlex
Phosphorylation of the cytoskeletal protein CAP1 controls its association with cofilin and actin (2014)

Journal of Cell Science 42 citations DOI OpenAlex
Mammalian CAP (Cyclase-associated protein) in the world of cell migration (2013)

Cell Adhesion & Migration 26 citations DOI OpenAlex
Mammalian Adenylyl Cyclase-associated Protein 1 (CAP1) Regulates Cofilin Function, the Actin Cytoskeleton, and Cell Adhesion (2013)

Journal of Biological Chemistry 93 citations DOI OpenAlex