Adam L. Corken
Sourced from institutional research profiles (UAMS TRI or ARA).
Associate Staff Scientist
Also affiliated: University of Illinois Chicago (2013); Arkansas Children's Nutrition Center (2022–2024); Arkansas Children's Research Institute (2024–2026)
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Adam Corken's research focuses on the role of platelets in chronic kidney disease (CKD) and related inflammatory processes. His work investigates how platelets contribute to disease progression and dysregulation in patients with advanced stages of CKD. Corken has explored the differential effects of antiplatelet medications, such as ticagrelor and clopidogrel, on platelet aggregation and inflammation in CKD patients. His studies also examine the broader impact of diet, such as a Western diet, on platelet activation profiles in animal models. Additionally, Corken has investigated the interaction between platelets and other cellular components, including leukocytes within perivascular adipose tissue, and has explored novel roles for platelet glycoproteins, such as glycoprotein Ibα, in radiation protection. He has published 23 papers, with an h-index of 10 and over 1,100 citations. Key collaborators include Keshari Thakali, Jerry Ware, Nishank Jain, and James D. Sikes, all from the University of Arkansas for Medical Sciences.
Metrics
- h-index: 10
- Publications: 23
- Citations: 1,135
Positions
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Associate Staff Scientist 2023–presentUniversity of Arkansas for Medical Sciences Pediatrics Institutional directory
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Associate Staff Scientist 2023–presentArkansas Children's Nutrition Center Pediatrics ORCID
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Postdoctoral Fellow 2020–2023Arkansas Children's Nutrition Center ORCID
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Postdoctoral Fellow 2020–2023University of Arkansas for Medical Sciences Pediatrics ORCID
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Adjunct Instructor 2022Hendrix College Biology ORCID
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Assistant Staff Scientist 2020University of Arkansas for Medical Sciences Physiology and Biophysics ORCID
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Forensic DNA Analyst 2015–2016Arkansas State Crime Laboratory Forensic DNA ORCID
Selected Publications
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Platelet glycoprotein VI modulates leukocyte characteristics in sepsis‐induced systemic inflammatory response in male mice (2026)
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Postweaning diet affects offspring metabolic outcomes more than maternal diet in male and female mice (2026)
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Platelets Modulate Leukocyte Population Composition Within Perivascular Adipose Tissue (2025)
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Western Diet Modifies Platelet Activation Profiles in Male Mice (2024)
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Platelets, inflammation, and purinergic receptors in chronic kidney disease (2024)
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Ticagrelor inhibits platelet aggregation and reduces inflammatory burden more than clopidogrel in patients with stages 4 or 5 chronic kidney disease (2023)
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Platelet-Dependent Inflammatory Dysregulation in Patients with Stages 4 or 5 Chronic Kidney Disease: A Mechanistic Clinical Study (2022)
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Maternal Obesity Programming of Perivascular Adipose Tissue and Associated Immune Cells: An Understudied Area With Few Answers and Many Questions (2022)
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Platelet glycoprotein Ibα provides radiation protection (2021)
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Role of Platelets in Chronic Kidney Disease (2021)
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Hemostasis vs. homeostasis: Platelets are essential for preserving vascular barrier function in the absence of injury or inflammation (2020)
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Platelet Glycoprotein VI Haplotypes and the Presentation of Paediatric Sepsis (2018)
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A dynamic platelet—tumor cell axis (2018)
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The varied distribution and impact of RAS codon and other key DNA alterations across the translocation cyclin D subgroups in multiple myeloma (2017)
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Platelets (2015)
Grants & Funding
As listed on this researcher's institutional profile.
- Platelet glycoprotein Ib-IX in endotoxemia and sepsis (Funded by: American Heart Association (SouthWest Affiliate))
- GR037176 Do platelets play a role in obesity and the modulation of perivascular adipose tissue function? UAMS ACHRI Flow Through
Collaboration Network
Top Collaborators
- Platelets at the interface of thrombosis, inflammation, and cancer
- Hemostasis vs. homeostasis: Platelets are essential for preserving vascular barrier function in the absence of injury or inflammation
- Platelet Glycoprotein Ib-IX as a Regulator of Systemic Inflammation
- Role for Platelet Glycoprotein Ib-IX and Effects of its Inhibition in Endotoxemia-Induced Thrombosis, Thrombocytopenia, and Mortality
- Role of Platelets in Chronic Kidney Disease
Showing 5 of 12 shared publications
- Maternal Obesity Programming of Perivascular Adipose Tissue and Associated Immune Cells: An Understudied Area With Few Answers and Many Questions
- Western Diet Modifies Platelet Activation Profiles in Male Mice
- Platelets Modulate Leukocyte Population Composition Within Perivascular Adipose Tissue
- Postweaning diet affects offspring metabolic outcomes more than maternal diet in male and female mice
- Platelet glycoprotein VI modulates leukocyte characteristics in sepsis‐induced systemic inflammatory response in male mice
- Role of Platelets in Chronic Kidney Disease
- Platelets, inflammation, and purinergic receptors in chronic kidney disease
- Platelet-Dependent Inflammatory Dysregulation in Patients with Stages 4 or 5 Chronic Kidney Disease: A Mechanistic Clinical Study
- Ticagrelor inhibits platelet aggregation and reduces inflammatory burden more than clopidogrel in patients with stages 4 or 5 chronic kidney disease
- Platelet Glycoprotein Ib-IX as a Regulator of Systemic Inflammation
- Platelet Glycoprotein VI Haplotypes and the Presentation of Paediatric Sepsis
- The Platelet Glycoprotein Ib-IX Axis In Murine Polymicrobial Sepsis
- Role of Platelets in Chronic Kidney Disease
- Platelet-Dependent Inflammatory Dysregulation in Patients with Stages 4 or 5 Chronic Kidney Disease: A Mechanistic Clinical Study
- Ticagrelor inhibits platelet aggregation and reduces inflammatory burden more than clopidogrel in patients with stages 4 or 5 chronic kidney disease
- Western Diet Modifies Platelet Activation Profiles in Male Mice
- Platelets Modulate Leukocyte Population Composition Within Perivascular Adipose Tissue
- Postweaning diet affects offspring metabolic outcomes more than maternal diet in male and female mice
- Western Diet Modifies Platelet Activation Profiles in Male Mice
- Platelets Modulate Leukocyte Population Composition Within Perivascular Adipose Tissue
- Postweaning diet affects offspring metabolic outcomes more than maternal diet in male and female mice
- Platelet Glycoprotein Ib-IX as a Regulator of Systemic Inflammation
- The Platelet Glycoprotein Ib-IX Axis In Murine Polymicrobial Sepsis
- Platelet Glycoprotein Ib-IX as a Regulator of Systemic Inflammation
- The Platelet Glycoprotein Ib-IX Axis In Murine Polymicrobial Sepsis
- Role of Platelets in Chronic Kidney Disease
- Platelet-Dependent Inflammatory Dysregulation in Patients with Stages 4 or 5 Chronic Kidney Disease: A Mechanistic Clinical Study
- Platelets, inflammation, and purinergic receptors in chronic kidney disease
- Platelet glycoprotein Ibα provides radiation protection
- Platelet-Dependent Inflammatory Dysregulation in Patients with Stages 4 or 5 Chronic Kidney Disease: A Mechanistic Clinical Study
- Ticagrelor inhibits platelet aggregation and reduces inflammatory burden more than clopidogrel in patients with stages 4 or 5 chronic kidney disease
- Platelet-Dependent Inflammatory Dysregulation in Patients with Stages 4 or 5 Chronic Kidney Disease: A Mechanistic Clinical Study
- Ticagrelor inhibits platelet aggregation and reduces inflammatory burden more than clopidogrel in patients with stages 4 or 5 chronic kidney disease
- Platelet-Dependent Inflammatory Dysregulation in Patients with Stages 4 or 5 Chronic Kidney Disease: A Mechanistic Clinical Study
- Ticagrelor inhibits platelet aggregation and reduces inflammatory burden more than clopidogrel in patients with stages 4 or 5 chronic kidney disease
- Platelets at the interface of thrombosis, inflammation, and cancer
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