Adriana Lelis Carvalho

Researcher

University of Arkansas for Medical Sciences

faculty

14 h-index 25 pubs 525 cited

Research Areas

Mitochondrial Function and Pathology Diet and metabolism studies Bone health and treatments Liver Disease Diagnosis and Treatment Phytochemicals and Antioxidant Activities Immune Cell Function and Interaction

Links

ORCID Research Group

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OverviewAI-generated summary

Adriana Lelis Carvalho's research program investigates the physiological and pathophysiological roles of mitochondria, particularly in the context of metabolic disorders and skeletal development. Her work has explored the impact of reactive oxygen species (ROS) on bone cell function and examined alterations in mitochondrial function during non-alcoholic fatty liver disease (NAFLD) progression. Carvalho has investigated the potential therapeutic effects of mitochondria-targeted antioxidants, such as AntiOxCIN4, in mitigating liver steatosis in mouse models. Additionally, her research has delved into the NAD salvage pathway's importance for skeletal development and the role of ECSIT in osteoclast function and estrogen's anti-osteoclastogenic effects. Her publication record includes studies on HepG2 cell toxicity, TRPM8's role in temperature regulation, and the influence of estradiol on osteoclast differentiation and mitochondrial metabolism. Carvalho holds a h-index of 14 with 525 citations across 25 publications and collaborates with researchers at the University of Arkansas for Medical Sciences, including Maria Almeida and Ha‐Neui Kim.

Metrics

  • h-index: 14
  • Publications: 25
  • Citations: 525

Selected Publications

  • The Aging Landscape by <scp>scRNAseq</scp> of Mesenchymal Lineage Cells in Mouse Bone (2025) DOI
  • CRISPR activation of <i>Tfeb</i> , a master regulator of autophagy and lysosomal biogenesis, in osteoblast lineage cells increases bone mass and strength (2024) DOI

Collaborators

Researchers in the database who share publications

Maria Almeida University of Arkansas for Medical Sciences 6 shared publications Ha‐Neui Kim University of Arkansas for Medical Sciences 5 shared publications Charles A. O’Brien University of Arkansas for Medical Sciences 2 shared publications Aaron Warren University of Arkansas for Medical Sciences 2 shared publications Landon B. Gatrell University of Arkansas for Medical Sciences 2 shared publications Olivia Reyes‐Castro University of Arkansas for Medical Sciences 2 shared publications Melda Onal University of Arkansas for Medical Sciences 2 shared publications A. Gordon James University of Arkansas for Medical Sciences 2 shared publications

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