Alan B. Diekman

High Impact

Professor

UAMS

Also affiliated: Northwestern University (1994–1998); Hope College (1993); University of Virginia Health System (2000–2002); Institute of Cell Biology (2004); University of Virginia (1997–2007)

Faculty Researcher

Biochemistry & Molecular Biology, College of Medicine

22 h-index 39 pubs 1,666 cited

Research Areas

Biomedical Subjects

Links

Research Group UAMS TRI Profile

OverviewAI-generated summary

Alan B. Diekman is a Professor in the Department of Biochemistry & Molecular Biology at the University of Arkansas for Medical Sciences. His research focuses on the molecular mechanisms underlying cancer development and progression. He has investigated the role of genetic variations, specifically single nucleotide polymorphisms (SNPs) in folate metabolism-related genes, and their impact on prostate cancer aggressiveness in different racial groups. His work has been published in peer-reviewed journals, with a notable recent publication in 2023. Diekman's scholarship metrics include an h-index of 22, with a total of 39 publications and 1,661 citations, designating him as a highly cited researcher. He collaborates with colleagues such as Lora J. Rogers and Calvin T. Ratliff, both at the University of Arkansas for Medical Sciences, with whom he has co-authored multiple publications.

Metrics

h-index: 22
Publications: 39
Citations: 1,666

Selected Publications

Interactions of SNPs in Folate Metabolism Related Genes on Prostate Cancer Aggressiveness in European Americans and African Americans (2023)

Cancers 3 citations DOI OpenAlex
Expression characterization and functional implication of the collagen-modifying Leprecan proteins in mouse gonadal tissue and mature sperm (2018)

Global Medical Genetics 5 citations DOI OpenAlex
Teaching Biochemistry and Genetics to Students of Medicine, Pharmacy, and Dentistry (2017)

Medical Science Educator 4 citations DOI OpenAlex
Teaching Biochemistry to Students of Medicine, Pharmacy and Dentistry (2015)

Medical Science Educator 2 citations DOI OpenAlex
Investigation of Galectin‐3 Function in the Reproductive Tract by Identification of Binding Ligands in Human Seminal Plasma (2014)

American Journal of Reproductive Immunology 28 citations DOI OpenAlex
Proteomic identification of galectin-3 binding ligands and characterization of galectin-3 proteolytic cleavage in human prostasomes (2013)

Andrology 28 citations DOI OpenAlex
Galectins and their Role in Various Biological Processes (2011)

DOI OpenAlex
Identification of calcium-binding proteins associated with the human sperm plasma membrane (2010)

Reproductive Biology and Endocrinology 37 citations DOI OpenAlex
Galectin‐3 is a substrate for prostate specific antigen (PSA) in human seminal plasma (2010)

The Prostate 41 citations DOI OpenAlex
Co‐purification of Mac‐2 binding protein with galectin‐3 and association with prostasomes in human semen (2010)

The Prostate 34 citations DOI OpenAlex
Galectin-3 is associated with prostasomes in human semen (2009)

Glycoconjugate Journal 59 citations DOI OpenAlex
Evaluation of Differentially Expressed Proteins Following Serum Exposure in Avian Pathogenic Escherichia coli (2008)

Avian Diseases Digest 2 citations DOI OpenAlex
Evaluation of Differentially Expressed Proteins Following Serum Exposure in Avian Pathogenic Escherichia coli (2008)

Avian Diseases 11 citations DOI OpenAlex
Glycoconjugates in sperm function and gamete interactions: how much sugar does it take to sweet-talk the egg? (2003)

Cellular and Molecular Life Sciences 95 citations DOI OpenAlex
A male genital tract‐specific carbohydrate epitope on human CD52: Implications for immunocontraception (2002)

Tissue Antigens 22 citations DOI OpenAlex

View all publications on OpenAlex →

Grants & Funding

As listed on this researcher's institutional profile.

Impact of genetic polymorphism and zinc on proteolytic cleavage of galectin-3 by prostate specific antigen (PSA) Urology Care Foundation of the American Urologic Association Other
Galectin-3 genetic and phenotypic polymorphism in breast cancer Arkansas Breast Cancer Research Program Principal Investigator
HUMAN SPERM ZONA BINDING PROTEIN NIH Principal Investigator
The galectin-3 SNP genotype as a marker of genetic predisposition for colorectal cancer UAMS Medical Research Foundation Principal Investigator
Galectin-3 genetic polymorphism as an etiological factor in diabetes and diabetic complications Sturgis Foundation Principal Investigator
Identification and characterization of galectin-3 binding ligands in the cytoskeleton of the human sperm flagellum Urology Care Foundation of the American Urologic Association Other
Prostasome interactions with female cervicovaginal epithelial cells: A Novel Paradigm for Women’s Reproductive Health UAMS College of Medicine Principal Investigator
Evaluation of galectin-3 as a biomarker for prostate cancer screening Urology Care Foundation of the American Urologic Association Other

Prostate cancer biomarker development based on galectin-3/prostate specific antigen (PSA) interactions US Department of the Army Principal Investigator
Diekman Start-up UAMS College of Medicine Principal Investigator
Impact of genetic polymorphism on galectin-3 function: Implications for prostate cancer Urology Care Foundation of the American Urologic Association Other
Mechanisms of RNA binding and remodeling proteins NIH Co-Investigator
Purification of prostate specific antigen (PSA) for prostate cancer studies Urology Care Foundation of the American Urologic Association Other
Impact of genetic polymorphism on galectin-3 oligomerization: Implications for prostate cancer Urology Care Foundation of the American Urologic Association Other
Peptide mimic for a human sperm-specific carbohydrate epitope UAMS Medical Research Foundation Principal Investigator
Molecular mechanism for modified citrus pectin in prostate cancer prevention Urology Care Foundation of the American Urologic Association Other
Medical Student Ed grant for Arkansas - Continuation - Revision Health Resources & Services Administration Principal Investigator
Impact of genetic polymorphism on the ability of galectin-3 to function as a zinc-binding protein UAMS College of Medicine Principal Investigator
Beta-galactoside-binding proteins in human spermatozoa UAMS College of Medicine Principal Investigator
Seeds of Science UAMS Principal Investigator
Impact of galectin-3 genetic polymorphism on zinc-binding and implications for prostate cancer Urology Care Foundation of the American Urologic Association Other
Immunologic Mechanisms in Human Female Infertility Sub Contract of NIH HD35523 University of Virginia Principal Investigator
Validation of a strategy to purify Prostate specific antigen (PSA) for prostate cancer (PCa) studies Urology Care Foundation of the American Urologic Association Other
Evaluation of lectin binding to prostate specific antigen (PSA) for biomarker development Urology Care Foundation of the American Urologic Association Other
Purification of prostate specific antigen (PSA) from seminal plasma for prostate cancer (PCa) research Urology Care Foundation of the American Urologic Association Other
Impact of divalent cations on proteolytic cleavage of galectin-3 by prostate specific antigen (PSA Urology Care Foundation of the American Urologic Association Other
Formulation and testing of a native S19 monoclonal antibody/Novasome® spermicidal cream Contraceptive Research and Development Program (CONRAD) Co-Investigator
Galectin-3 single nucleotide polymorphisms as etiological factors in type 1 diabetes Sturgis Foundation Principal Investigator
Role of galectin-3 in genital tract immunosuppression NIH Principal Investigator
RECOMBINANT ANTIBODIES AS INTRA VAGINAL SPERMICIDES NIH Principal Investigator
In vivo, noninvasive, ultrasensitive photoacoustic detection of early breast cancer metastasis in bone US Department of the Army Principal Investigator
Galectin-3 as a biomarker for prostate cancer screening Urology Care Foundation of the American Urologic Association Other
Carbohydrate immunocontraceptive epitopes identified in a neoglycolipid library derived from the human sperm glycocalyx Mellon Foundation Principal Investigator
Value-Based Medical Student Education Training Program Health Resources and Services Administration Other
Identification and characterization of galectin-3 binding ligands in the outer dense fibers of the human sperm tail Urology Care Foundation of the American Urologic Association Other
Galectin-3 genetic polymorphism and proteolytic cleavage by prostate specific antigen (PSA) in prostate cancer progression Urology Care Foundation of the American Urologic Association Other
Investigation of galectin-3 as a zinc-binding protein and implications for prostate cancer Urology Care Foundation of the American Urologic Association Other
Role of GPI-Anchored CD52 Glycoprotein in Sperm Function NIH Principal Investigator
Immunologic mechanisms in human female infertility NIH Co-Investigator
Molecular interactions between prostate specific antigen and galectin-3 Urology Care Foundation of the American Urologic Association Other
Investigation of serum galectin-3 as a biomarker for prostate cancer screening Urology Care Foundation of the American Urologic Association Other