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OverviewAI-generated summary
Lora J. Rogers' research investigates the interplay between genetic factors, environmental exposures, and disease development, with a particular focus on cancer and metabolic disorders. Her work has explored the association of environmental heavy metals with obesity in postmenopausal women and examined the role of specific gene polymorphisms in prostate cancer aggressiveness. Rogers has also investigated the immunological responses to cancer therapies, including the combination of a vaccine with neoadjuvant chemotherapy in breast cancer patients. Her recent publications delve into the molecular mechanisms of T cell function, including the impact of DNA damage response pathways and metabolic plasticity in glioblastoma. Rogers collaborates with several faculty members at the University of Arkansas for Medical Sciences, including Brian Koss, Daniel Fil, Shelbie Stahr, and Gail Runnells.
Metrics
- h-index: 9
- Publications: 60
- Citations: 232
Selected Publications
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Additional file 2 of Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study (2026)
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Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study (2026)
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Additional file 2 of Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study (2026)
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Additional file 1 of Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study (2026)
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Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study (2026)
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Additional file 1 of Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study (2026)
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Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study (2026)
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685 EZH2 inhibition impairs CD8+ CAR-T cell persistence (2025)
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762 CD28 costimulation induces PCK2 to support T cell effector function in metabolically hostile environments (2025)
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236 Manipulating the DNA damage response to combat T cell exhaustion and improve immunotherapy response (2025)
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277 Proteome turnover dynamics analysis uncovers E3 ligases that enhance T-cell persistence during exhaustion (2025)
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392 Donor-intrinsic proteomic programs shape CAR-T cell persistence across a longitudinal killing assay (2025)
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Comprehensive Analysis of Proteome Turnover Dynamics During T Cell Exhaustion (2025)
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319 Comprehensive analysis of proteome turnover dynamics during T cell exhaustion (2024)
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932 Defining the role for PCK2 in T-cell metabolic plasticity (2024)
Collaboration Network
Top Collaborators
- Adipocyte hypoxia promotes epithelial-mesenchymal transition-related gene expression and estrogen receptor-negative phenotype in breast cancer cells
- A functional SNP in the 3′‐UTR of TAP2 gene interacts with microRNA hsa‐miR‐1270 to suppress the gene expression
- Sulfotransferase 1A1 (SULT1A1) gene expression is regulated by members of the NFI transcription factors in human breast cancer cells
- Low-Level Environmental Heavy Metals are Associated with Obesity Among Postmenopausal Women in a Southern State
- 2-amino-1-methyl-6-phenylimidazo(4,5-b) pyridine (PhIP) induces gene expression changes in JAK/STAT and MAPK pathways related to inflammation, diabetes and cancer
Showing 5 of 22 shared publications
- Genome-wide DNA methylation signatures to predict pathologic complete response from combined neoadjuvant chemotherapy with bevacizumab in breast cancer
- County poverty levels influence genome-wide DNA methylation profiles in African American and European American women
- Association of DNA-Methylation Profiles With Immune Responses Elicited in Breast Cancer Patients Immunized With a Carbohydrate-Mimicking Peptide: A Pilot Study
- Abstract 4180: Association between genetic polymorphisms of DNMT genes and breast cancer in a nested case-control study of African Americans
- Abstract 815: Genome-wide DNA methylation signatures to predict pathologic complete response from combined neoadjuvant chemotherapy with bevacizumab in breast cancer
Showing 5 of 18 shared publications
- Low-Level Environmental Heavy Metals are Associated with Obesity Among Postmenopausal Women in a Southern State
- Abstract C049: The association between breast cancer and physical activity levels by race in a prospective cohort study
- Association between breast cancer risk and leisure physical activity in a rural cohort population
- Abstract 1450: Interactions of DNMTs genetic variants associated with breast cancer risk
- Abstract 1443: Environmental heavy metal toxicity and mammographic breast density in a Mississippi Delta southern state
Showing 5 of 17 shared publications
- Chemical inhibition of DNA‐PKcs impairs the activation and cytotoxicity of CD4 + helper and CD8 + effector T cells
- 1020 Proteomic analysis of T cell exhaustion unveils differential modulation of the DNA damage response
- 1211 Defining the role of PCK2 in T cell metabolic plasticity in Glioblastoma
- Inhibition of DNA-PKcs impairs the activation and cytotoxicity of CD4 + helper and CD8 + effector T cells
- Abstract B015: Racial differences in epigenetic aging and its impact on expression of T-cell inhibitory receptors
Showing 5 of 15 shared publications
- Low-Level Environmental Heavy Metals are Associated with Obesity Among Postmenopausal Women in a Southern State
- County poverty levels influence genome-wide DNA methylation profiles in African American and European American women
- Abstract 4180: Association between genetic polymorphisms of DNMT genes and breast cancer in a nested case-control study of African Americans
- Abstract C062: Racial differences in genome-wide DNA methylation profiles by county poverty levels among women residing in Arkansas
- Abstract C049: The association between breast cancer and physical activity levels by race in a prospective cohort study
Showing 5 of 13 shared publications
- Chemical inhibition of DNA‐PKcs impairs the activation and cytotoxicity of CD4 + helper and CD8 + effector T cells
- 1020 Proteomic analysis of T cell exhaustion unveils differential modulation of the DNA damage response
- 1211 Defining the role of PCK2 in T cell metabolic plasticity in Glioblastoma
- 255 Functional and multi-omic characterization of CAR T cells across healthy donors
- 304 Discovering T cell proteome turnover dynamics to enhance persistence in solid tumors
Showing 5 of 12 shared publications
- Low-Level Environmental Heavy Metals are Associated with Obesity Among Postmenopausal Women in a Southern State
- 1211 Defining the role of PCK2 in T cell metabolic plasticity in Glioblastoma
- Abstract B015: Racial differences in epigenetic aging and its impact on expression of T-cell inhibitory receptors
- 255 Functional and multi-omic characterization of CAR T cells across healthy donors
- 304 Discovering T cell proteome turnover dynamics to enhance persistence in solid tumors
Showing 5 of 11 shared publications
- 1020 Proteomic analysis of T cell exhaustion unveils differential modulation of the DNA damage response
- 1211 Defining the role of PCK2 in T cell metabolic plasticity in Glioblastoma
- 304 Discovering T cell proteome turnover dynamics to enhance persistence in solid tumors
- 932 Defining the role for PCK2 in T-cell metabolic plasticity
- 319 Comprehensive analysis of proteome turnover dynamics during T cell exhaustion
Showing 5 of 11 shared publications
- Adipocyte hypoxia promotes epithelial-mesenchymal transition-related gene expression and estrogen receptor-negative phenotype in breast cancer cells
- Sulfotransferase 1A1 (SULT1A1) gene expression is regulated by members of the NFI transcription factors in human breast cancer cells
- 2-amino-1-methyl-6-phenylimidazo(4,5-b) pyridine (PhIP) induces gene expression changes in JAK/STAT and MAPK pathways related to inflammation, diabetes and cancer
- Fulvestrant up regulates UGT1A4 and MRP s through ERα and c-Myb pathways: a possible primary drug disposition mechanism
- Abstract 5550: SNPs in UDP-glucuronosyltransferase1A4 (UGT1A4) and multidrug resistant protein (MRP) and their influence on anastrozole metabolism and disposition
Showing 5 of 8 shared publications
- 1020 Proteomic analysis of T cell exhaustion unveils differential modulation of the DNA damage response
- 304 Discovering T cell proteome turnover dynamics to enhance persistence in solid tumors
- 932 Defining the role for PCK2 in T-cell metabolic plasticity
- 319 Comprehensive analysis of proteome turnover dynamics during T cell exhaustion
- Comprehensive Analysis of Proteome Turnover Dynamics During T Cell Exhaustion
Showing 5 of 8 shared publications
- Low-Level Environmental Heavy Metals are Associated with Obesity Among Postmenopausal Women in a Southern State
- Abstract 4180: Association between genetic polymorphisms of DNMT genes and breast cancer in a nested case-control study of African Americans
- Abstract D097: Association between high mammographic density and environmental chromium and arsenic exposure in a pilot study of women living in rural communities
- Abstract 4180: Association between genetic polymorphisms of DNMT genes and breast cancer in a nested case-control study of African Americans
- Abstract 1450: Interactions of DNMTs genetic variants associated with breast cancer risk
Showing 5 of 7 shared publications
- Low-Level Environmental Heavy Metals are Associated with Obesity Among Postmenopausal Women in a Southern State
- Abstract D097: Association between high mammographic density and environmental chromium and arsenic exposure in a pilot study of women living in rural communities
- Association between breast cancer risk and leisure physical activity in a rural cohort population
- Abstract 1450: Interactions of DNMTs genetic variants associated with breast cancer risk
- Saliva and Urine Sampling to Quantify Trace Metal Exposure for Epidemiologic Studies
Showing 5 of 7 shared publications
- Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study
- Additional file 1 of Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study
- Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study
- Additional file 1 of Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study
- Additional file 2 of Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study
Showing 5 of 7 shared publications
- Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study
- Additional file 1 of Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study
- Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study
- Additional file 1 of Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study
- Additional file 2 of Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study
Showing 5 of 7 shared publications
- Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study
- Additional file 1 of Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study
- Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study
- Additional file 1 of Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study
- Additional file 2 of Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study
Showing 5 of 7 shared publications
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