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OverviewAI-generated summary
Lora J. Rogers' research interests include the intersection of environmental factors, genetics, and disease, with a particular focus on cancer and metabolic health. Her work has investigated the association between low-level environmental heavy metals and obesity in postmenopausal women. Rogers has also explored the role of genetic variations, such as SNPs in folate metabolism-related genes, in prostate cancer aggressiveness and the association of DNA methyltransferase polymorphisms with breast cancer risk in rural Arkansas populations. Her research extends to the cellular and molecular mechanisms of cancer, including the impact of specific gene inhibitions, like EZH2, on CAR-T cell persistence and the role of DNA-PKcs in T cell function. She has also examined T cell exhaustion and metabolic plasticity in glioblastoma. Rogers has a publication record of 60 papers and a citation count of 224, with an h-index of 9. She has collaborated extensively with colleagues at the University of Arkansas for Medical Sciences, including Brian Koss, Daniel Fil, Shelbie Stahr, and Gail Runnells.
Metrics
- h-index: 9
- Publications: 60
- Citations: 225
Selected Publications
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Additional file 2 of Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study (2026)
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Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study (2026)
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Additional file 2 of Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study (2026)
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Additional file 1 of Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study (2026)
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Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study (2026)
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Additional file 1 of Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study (2026)
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Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study (2026)
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685 EZH2 inhibition impairs CD8+ CAR-T cell persistence (2025)
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762 CD28 costimulation induces PCK2 to support T cell effector function in metabolically hostile environments (2025)
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236 Manipulating the DNA damage response to combat T cell exhaustion and improve immunotherapy response (2025)
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277 Proteome turnover dynamics analysis uncovers E3 ligases that enhance T-cell persistence during exhaustion (2025)
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392 Donor-intrinsic proteomic programs shape CAR-T cell persistence across a longitudinal killing assay (2025)
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Comprehensive Analysis of Proteome Turnover Dynamics During T Cell Exhaustion (2025)
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319 Comprehensive analysis of proteome turnover dynamics during T cell exhaustion (2024)
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932 Defining the role for PCK2 in T-cell metabolic plasticity (2024)
Collaboration Network
Top Collaborators
Brian Koss
University of Arkansas for Medical Sciences
15 shared publications
In database
- Chemical inhibition of <scp>DNA‐PKcs</scp> impairs the activation and cytotoxicity of <scp>CD4</scp><sup>+</sup> helper and <scp>CD8</scp><sup>+</sup> effector T cells
- 1020 Proteomic analysis of T cell exhaustion unveils differential modulation of the DNA damage response
- 1211 Defining the role of PCK2 in T cell metabolic plasticity in Glioblastoma
- Inhibition of DNA-PKcs impairs the activation and cytotoxicity of CD4 <sup>+</sup> helper and CD8 <sup>+</sup> effector T cells
- Abstract B015: Racial differences in epigenetic aging and its impact on expression of T-cell inhibitory receptors
Showing 5 of 15 shared publications
Daniel Fil
University of Arkansas for Medical Sciences
12 shared publications
In database
- Chemical inhibition of <scp>DNA‐PKcs</scp> impairs the activation and cytotoxicity of <scp>CD4</scp><sup>+</sup> helper and <scp>CD8</scp><sup>+</sup> effector T cells
- 1020 Proteomic analysis of T cell exhaustion unveils differential modulation of the DNA damage response
- 1211 Defining the role of PCK2 in T cell metabolic plasticity in Glioblastoma
- 255 Functional and multi-omic characterization of CAR T cells across healthy donors
- 304 Discovering T cell proteome turnover dynamics to enhance persistence in solid tumors
Showing 5 of 12 shared publications
Michael Bauer
University of Arkansas for Medical Sciences
11 shared publications
In database
- Low-Level Environmental Heavy Metals are Associated with Obesity Among Postmenopausal Women in a Southern State
- 1211 Defining the role of PCK2 in T cell metabolic plasticity in Glioblastoma
- Abstract B015: Racial differences in epigenetic aging and its impact on expression of T-cell inhibitory receptors
- 255 Functional and multi-omic characterization of CAR T cells across healthy donors
- 304 Discovering T cell proteome turnover dynamics to enhance persistence in solid tumors
Showing 5 of 11 shared publications
Sydnye L. Shuttleworth
University of Arkansas for Medical Sciences
11 shared publications
In database
- 1020 Proteomic analysis of T cell exhaustion unveils differential modulation of the DNA damage response
- 1211 Defining the role of PCK2 in T cell metabolic plasticity in Glioblastoma
- 304 Discovering T cell proteome turnover dynamics to enhance persistence in solid tumors
- 932 Defining the role for PCK2 in T-cell metabolic plasticity
- 319 Comprehensive analysis of proteome turnover dynamics during T cell exhaustion
Showing 5 of 11 shared publications
Shelbie Stahr
University of Arkansas for Medical Sciences
9 shared publications
In database
- Low-Level Environmental Heavy Metals are Associated with Obesity Among Postmenopausal Women in a Southern State
- Abstract 1450: Interactions of <i>DNMTs</i> genetic variants associated with breast cancer risk
- Abstract 1443: Environmental heavy metal toxicity and mammographic breast density in a Mississippi Delta southern state
- Genome-wide DNA methylation landscape associated with high arsenic exposure
- Genome-wide DNA methylation landscape associated with high arsenic exposure
Showing 5 of 9 shared publications
Jessica L Kelliher
University of Arkansas for Medical Sciences (US)
8 shared publications
- 1020 Proteomic analysis of T cell exhaustion unveils differential modulation of the DNA damage response
- 304 Discovering T cell proteome turnover dynamics to enhance persistence in solid tumors
- 932 Defining the role for PCK2 in T-cell metabolic plasticity
- 319 Comprehensive analysis of proteome turnover dynamics during T cell exhaustion
- Comprehensive Analysis of Proteome Turnover Dynamics During T Cell Exhaustion
Showing 5 of 8 shared publications
Gail Runnells
University of Arkansas for Medical Sciences
6 shared publications
In database
- Low-Level Environmental Heavy Metals are Associated with Obesity Among Postmenopausal Women in a Southern State
- Abstract 1450: Interactions of <i>DNMTs</i> genetic variants associated with breast cancer risk
- Abstract 1443: Environmental heavy metal toxicity and mammographic breast density in a Mississippi Delta southern state
- Genome-wide DNA methylation landscape associated with high arsenic exposure
- Early-Onset Breast Cancer and Geospatial Indicators of Exposures in the Arkansas Rural Community Health Study (ARCH)
Showing 5 of 6 shared publications
L. Joseph Su
Southwestern Medical Center
5 shared publications
- Low-Level Environmental Heavy Metals are Associated with Obesity Among Postmenopausal Women in a Southern State
- Abstract 1450: Interactions of <i>DNMTs</i> genetic variants associated with breast cancer risk
- Saliva and Urine Sampling to Quantify Trace Metal Exposure for Epidemiologic Studies
- Early-Onset Breast Cancer and Geospatial Indicators of Exposures in the Arkansas Rural Community Health Study (ARCH)
- Cumulative arsenic exposure from residential histories and its association with individual arsenic levels in saliva
Alan J. Tackett
University of Arkansas for Medical Sciences
5 shared publications
In database
- 304 Discovering T cell proteome turnover dynamics to enhance persistence in solid tumors
- 319 Comprehensive analysis of proteome turnover dynamics during T cell exhaustion
- Comprehensive Analysis of Proteome Turnover Dynamics During T Cell Exhaustion
- 277 Proteome turnover dynamics analysis uncovers E3 ligases that enhance T-cell persistence during exhaustion
- 685 EZH2 inhibition impairs CD8+ CAR-T cell persistence
Tung-Chin Chiang
University of Arkansas for Medical Sciences
4 shared publications
In database
- Low-Level Environmental Heavy Metals are Associated with Obesity Among Postmenopausal Women in a Southern State
- Abstract 1450: Interactions of <i>DNMTs</i> genetic variants associated with breast cancer risk
- Abstract 1443: Environmental heavy metal toxicity and mammographic breast density in a Mississippi Delta southern state
- Abstract B015: Racial differences in epigenetic aging and its impact on expression of T-cell inhibitory receptors
Ping-Ching Hsu
University of Arkansas for Medical Sciences
4 shared publications
In database
- Abstract 1450: Interactions of <i>DNMTs</i> genetic variants associated with breast cancer risk
- Abstract B015: Racial differences in epigenetic aging and its impact on expression of T-cell inhibitory receptors
- Saliva and Urine Sampling to Quantify Trace Metal Exposure for Epidemiologic Studies
- Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study
Aaron J. Storey
Arkana Laboratories
4 shared publications
In database
- 304 Discovering T cell proteome turnover dynamics to enhance persistence in solid tumors
- 319 Comprehensive analysis of proteome turnover dynamics during T cell exhaustion
- Comprehensive Analysis of Proteome Turnover Dynamics During T Cell Exhaustion
- 277 Proteome turnover dynamics analysis uncovers E3 ligases that enhance T-cell persistence during exhaustion
P. C. Hsu
University of Arkansas for Medical Sciences
4 shared publications
In database
- Genome-wide DNA methylation landscape associated with high arsenic exposure
- Genome-wide DNA methylation landscape associated with high arsenic exposure
- Early-Onset Breast Cancer and Geospatial Indicators of Exposures in the Arkansas Rural Community Health Study (ARCH)
- Cumulative arsenic exposure from residential histories and its association with individual arsenic levels in saliva
Edgar T. Ellis
University of Arkansas for Medical Sciences (US)
4 shared publications
- Genome-wide DNA methylation landscape associated with high arsenic exposure
- Saliva and Urine Sampling to Quantify Trace Metal Exposure for Epidemiologic Studies
- Early-Onset Breast Cancer and Geospatial Indicators of Exposures in the Arkansas Rural Community Health Study (ARCH)
- Cumulative arsenic exposure from residential histories and its association with individual arsenic levels in saliva
Katherine Wallis
University of Arkansas for Medical Sciences
4 shared publications
In database
- 932 Defining the role for PCK2 in T-cell metabolic plasticity
- 236 Manipulating the DNA damage response to combat T cell exhaustion and improve immunotherapy response
- 762 CD28 costimulation induces PCK2 to support T cell effector function in metabolically hostile environments
- 685 EZH2 inhibition impairs CD8+ CAR-T cell persistence
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