Landen W. Saling Source Confirmed
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Researcher
University of Arkansas at Fayetteville
faculty
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Biography and Research Information
OverviewAI-generated summary
Landen W. Saling's research focuses on the biological sex differences in the development of cancer cachexia, a complex metabolic syndrome characterized by involuntary weight loss and muscle wasting. His work investigates the molecular and physiological alterations that occur during cachexia, with a particular emphasis on skeletal muscle fibrosis, insulin sensitivity, and protein turnover.
Saling has published studies examining changes in mitochondrial quality control markers and the induction of protein turnover regulators between biological sexes in response to cancer cachexia. His research also explores the role of microRNAs, such as miR-16, in regulating muscle function and insulin sensitivity in a sex-dependent manner. Additionally, his work has investigated transcriptomic analyses of soleus muscle in response to sarcopenic obesity.
His publications include collaborations with researchers at the University of Arkansas at Fayetteville, including Tyrone A. Washington, Seongkyun Lim, Eleanor R. Schrems, and Nicholas P. Greene. Saling's scholarship metrics include an h-index of 4, with 10 total publications and 82 total citations.
Metrics
- h-index: 4
- Publications: 10
- Citations: 82
Selected Publications
- Females display relatively preserved muscle quality compared with males during the onset and early stages of C26-induced cancer cachexia (2023) DOI
- Development of skeletal muscle fibrosis in a rodent model of cancer cachexia (2023) DOI
- Biological Sex Differences of Fibrosis During the Development of Cancer Cachexia (2023) DOI
- Differential Induction Of Regulators Of Protein Turnover During C26-induced Cancer Cachexia Between Biological Sexes (2022) DOI
- Muscle miR-16 deletion results in impaired insulin sensitivity and contractile function in a sex-dependent manner (2022) DOI
- Development of metabolic and contractile alterations in development of cancer cachexia in female tumor-bearing mice (2021) DOI
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