L
Landen W. Saling Data-verified
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Researcher
faculty
4 h-index
10 pubs
85 cited
Research Areas
Biography and Research Information
OverviewAI-generated summary
Landen W. Saling's research focuses on the biological sex differences in the development of cancer cachexia, a complex metabolic syndrome characterized by involuntary weight loss and muscle wasting. His work investigates the molecular and physiological alterations that occur in skeletal muscle during this condition, utilizing rodent models. Saling has published studies examining fibrosis development, mitochondrial function, and protein turnover regulators in response to cancer cachexia, highlighting differential impacts between biological sexes. His research also explores the role of specific microRNAs, such as miR-16, in regulating insulin sensitivity and muscle contractile function in a sex-dependent manner. Saling collaborates with several researchers at the University of Arkansas at Fayetteville, including Tyrone A. Washington, Seongkyun Lim, Eleanor R. Schrems, and Nicholas P. Greene, with whom he has co-authored multiple publications.
Metrics
- h-index: 4
- Publications: 10
- Citations: 85
Selected Publications
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Females display relatively preserved muscle quality compared with males during the onset and early stages of C26-induced cancer cachexia (2023)
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Development of skeletal muscle fibrosis in a rodent model of cancer cachexia (2023)
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Biological Sex Differences of Fibrosis During the Development of Cancer Cachexia (2023)
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Differential Induction Of Regulators Of Protein Turnover During C26-induced Cancer Cachexia Between Biological Sexes (2022)
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Muscle miR-16 deletion results in impaired insulin sensitivity and contractile function in a sex-dependent manner (2022)
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Development of metabolic and contractile alterations in development of cancer cachexia in female tumor-bearing mice (2021)
Collaboration Network
Top Collaborators
Seongkyun Lim
University of Arkansas at Fayetteville
10 shared publications
In database
- Development of metabolic and contractile alterations in development of cancer cachexia in female tumor-bearing mice
- Females display relatively preserved muscle quality compared with males during the onset and early stages of C26-induced cancer cachexia
- Muscle miR-16 deletion results in impaired insulin sensitivity and contractile function in a sex-dependent manner
- Development of skeletal muscle fibrosis in a rodent model of cancer cachexia
- Growth Differentiation Factor 5 Is A Paracrine Regulator In Sarcopenic Obesity
Showing 5 of 10 shared publications
Tyrone A. Washington
University of Arkansas at Fayetteville
10 shared publications
In database
- Development of metabolic and contractile alterations in development of cancer cachexia in female tumor-bearing mice
- Females display relatively preserved muscle quality compared with males during the onset and early stages of C26-induced cancer cachexia
- Muscle miR-16 deletion results in impaired insulin sensitivity and contractile function in a sex-dependent manner
- Development of skeletal muscle fibrosis in a rodent model of cancer cachexia
- Growth Differentiation Factor 5 Is A Paracrine Regulator In Sarcopenic Obesity
Showing 5 of 10 shared publications
Nicholas P. Greene
University of Arkansas at Fayetteville
10 shared publications
In database
- Development of metabolic and contractile alterations in development of cancer cachexia in female tumor-bearing mice
- Females display relatively preserved muscle quality compared with males during the onset and early stages of C26-induced cancer cachexia
- Muscle miR-16 deletion results in impaired insulin sensitivity and contractile function in a sex-dependent manner
- Development of skeletal muscle fibrosis in a rodent model of cancer cachexia
- Growth Differentiation Factor 5 Is A Paracrine Regulator In Sarcopenic Obesity
Showing 5 of 10 shared publications
Eleanor R. Schrems
University of Arkansas at Fayetteville
9 shared publications
In database
- Development of metabolic and contractile alterations in development of cancer cachexia in female tumor-bearing mice
- Females display relatively preserved muscle quality compared with males during the onset and early stages of C26-induced cancer cachexia
- Muscle miR-16 deletion results in impaired insulin sensitivity and contractile function in a sex-dependent manner
- Development of skeletal muscle fibrosis in a rodent model of cancer cachexia
- Growth Differentiation Factor 5 Is A Paracrine Regulator In Sarcopenic Obesity
Showing 5 of 9 shared publications
Francielly Morena da Silva
University of Arkansas at Fayetteville
8 shared publications
In database
- Development of metabolic and contractile alterations in development of cancer cachexia in female tumor-bearing mice
- Females display relatively preserved muscle quality compared with males during the onset and early stages of C26-induced cancer cachexia
- Muscle miR-16 deletion results in impaired insulin sensitivity and contractile function in a sex-dependent manner
- Growth Differentiation Factor 5 Is A Paracrine Regulator In Sarcopenic Obesity
- C26 Colorectal Cancer-cachexia Implications In Muscle Contractile Function And Calcium Regulation: A Biological Sex Comparison
Showing 5 of 8 shared publications
Ana Regina Cabrera
University of Arkansas at Fayetteville
7 shared publications
In database
- Development of metabolic and contractile alterations in development of cancer cachexia in female tumor-bearing mice
- Females display relatively preserved muscle quality compared with males during the onset and early stages of C26-induced cancer cachexia
- Muscle miR-16 deletion results in impaired insulin sensitivity and contractile function in a sex-dependent manner
- Growth Differentiation Factor 5 Is A Paracrine Regulator In Sarcopenic Obesity
- C26 Colorectal Cancer-cachexia Implications In Muscle Contractile Function And Calcium Regulation: A Biological Sex Comparison
Showing 5 of 7 shared publications
J. William Deaver
University of Arkansas at Fayetteville (US)
6 shared publications
- Development of metabolic and contractile alterations in development of cancer cachexia in female tumor-bearing mice
- Females display relatively preserved muscle quality compared with males during the onset and early stages of C26-induced cancer cachexia
- Muscle miR-16 deletion results in impaired insulin sensitivity and contractile function in a sex-dependent manner
- C26 Colorectal Cancer-cachexia Implications In Muscle Contractile Function And Calcium Regulation: A Biological Sex Comparison
- Differential Induction Of Regulators Of Protein Turnover During C26-induced Cancer Cachexia Between Biological Sexes
Showing 5 of 6 shared publications
Megan E. Rosa‐Caldwell
Harvard University
5 shared publications
In database
- Development of metabolic and contractile alterations in development of cancer cachexia in female tumor-bearing mice
- Females display relatively preserved muscle quality compared with males during the onset and early stages of C26-induced cancer cachexia
- Muscle miR-16 deletion results in impaired insulin sensitivity and contractile function in a sex-dependent manner
- Development of skeletal muscle fibrosis in a rodent model of cancer cachexia
- Biological Sex Differences of Fibrosis During the Development of Cancer Cachexia
Wesley S. Haynie
University of Arkansas at Fayetteville
3 shared publications
In database
- Development of metabolic and contractile alterations in development of cancer cachexia in female tumor-bearing mice
- Development of skeletal muscle fibrosis in a rodent model of cancer cachexia
- Biological Sex Differences of Fibrosis During the Development of Cancer Cachexia
Michael P. Wiggs
Baylor University (US)
2 shared publications
- Development of metabolic and contractile alterations in development of cancer cachexia in female tumor-bearing mice
- Females display relatively preserved muscle quality compared with males during the onset and early stages of C26-induced cancer cachexia
David E. Lee
University of Arkansas at Fayetteville (US)
2 shared publications
- Muscle miR-16 deletion results in impaired insulin sensitivity and contractile function in a sex-dependent manner
- Development of skeletal muscle fibrosis in a rodent model of cancer cachexia
Breanna Williams
2 shared publications
- Growth Differentiation Factor 5 Is A Paracrine Regulator In Sarcopenic Obesity
- Transcriptomic Analysis Of Soleus Muscle In Response To Sarcopenic Obesity
Anthony Campitelli
2 shared publications
In database
- Differential Induction Of Regulators Of Protein Turnover During C26-induced Cancer Cachexia Between Biological Sexes
- Mitochondrial Quality Control Markers During The Onset Of Colorectal Cancer-induced Cachexia: A Biological Sex Comparison
Jacob L. Brown
University of Arkansas at Fayetteville (US)
2 shared publications
- Development of skeletal muscle fibrosis in a rodent model of cancer cachexia
- Biological Sex Differences of Fibrosis During the Development of Cancer Cachexia
Richard Perry
University of Arkansas at Fayetteville (US)
2 shared publications
- Development of skeletal muscle fibrosis in a rodent model of cancer cachexia
- Biological Sex Differences of Fibrosis During the Development of Cancer Cachexia
Similar Researchers
Based on overlapping research topics
Ruqaiza Muhyudin
University of Arkansas at Fayetteville
Cancer-related molecular mechanisms research
Muscle Physiology and Disorders
Mitochondrial Function and Pathology
Nicholas P. Greene
University of Arkansas at Fayetteville
Cancer-related molecular mechanisms research
Muscle Physiology and Disorders
Mitochondrial Function and Pathology
Francielle Morena Da Silva
University of Arkansas at Fayetteville
Cancer-related molecular mechanisms research
Mitochondrial Function and Pathology
Metabolism and Genetic Disorders
Eleanor R. Schrems
University of Arkansas at Fayetteville
Cancer-related molecular mechanisms research
Muscle Physiology and Disorders
Mitochondrial Function and Pathology
Megan E. Rosa‐Caldwell
University of Arkansas at Fayetteville
Cancer-related molecular mechanisms research
Muscle Physiology and Disorders
Mitochondrial Function and Pathology
Clayre Parson
University of Arkansas at Fayetteville
Mitochondrial Function and Pathology
Metabolism and Genetic Disorders
Animal Behavior and Welfare Studies