A
Andrew Brown Data-verified
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Researcher
faculty
14 h-index
55 pubs
1,522 cited
Research Areas
Links
Biography and Research Information
OverviewAI-generated summary
Andrew Brown's research focuses on understanding the molecular mechanisms underlying immune responses and disease states. His work has investigated the epigenomic landscape of human monocytes during innate immune activation, revealing context-specific pathways that drive endotoxin tolerance. He has also explored the epigenomic profiling of ankylosing spondylitis to inform target discovery and examined the characteristics of COVID-19 severity through blood atlas studies. Brown's publications include work on identifying structural variations in immune system gene regions using de novo assembly and the development of radiotranscriptomic signatures for vascular inflammation in COVID-19 patients. His scholarship includes 55 publications with 1,522 citations and an h-index of 14.
Metrics
- h-index: 14
- Publications: 55
- Citations: 1,522
Selected Publications
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Abstract 048: Effects of Replacing Solid Fats and Added Sugars with Avocado in Adults with Elevated Cardiometabolic Risk: A Randomized Controlled Trial (2025)
Collaboration Network
Top Collaborators
Julian C. Knight
Centre for Human Genetics (GB)
26 shared publications
- Using de novo assembly to identify structural variation of eight complex immune system gene regions
- Constructing custom-made radiotranscriptomic signatures of vascular inflammation from routine CT angiograms: a prospective outcomes validation study in COVID-19
- Epigenomic analysis reveals a dynamic and context-specific macrophage enhancer landscape associated with innate immune activation and tolerance
- Comprehensive epigenomic profiling reveals the extent of disease-specific chromatin states and informs target discovery in ankylosing spondylitis
- Mapping the epigenomic landscape of human monocytes following innate immune activation reveals context-specific mechanisms driving endotoxin tolerance
Showing 5 of 26 shared publications
Alice Allcock
University of Oxford (GB)
22 shared publications
- A blood atlas of COVID-19 defines hallmarks of disease severity and specificity
- A blood atlas of COVID-19 defines hallmarks of disease severity and specificity
- Epigenomic analysis reveals a dynamic and context-specific macrophage enhancer landscape associated with innate immune activation and tolerance
- Comprehensive epigenomic profiling reveals the extent of disease-specific chromatin states and informs target discovery in ankylosing spondylitis
- Mapping the epigenomic landscape of human monocytes following innate immune activation reveals context-specific mechanisms driving endotoxin tolerance
Showing 5 of 22 shared publications
Giuseppe Scozzafava
Centre for Human Genetics (GB)
22 shared publications
- Epigenomic analysis reveals a dynamic and context-specific macrophage enhancer landscape associated with innate immune activation and tolerance
- Comprehensive epigenomic profiling reveals the extent of disease-specific chromatin states and informs target discovery in ankylosing spondylitis
- Mapping the epigenomic landscape of human monocytes following innate immune activation reveals context-specific mechanisms driving endotoxin tolerance
- Mapping the epigenomic landscape of human monocytes following innate immune activation reveals context-specific mechanisms driving endotoxin tolerance
- Mapping the epigenomic landscape of human monocytes following innate immune activation reveals context-specific mechanisms driving endotoxin tolerance
Showing 5 of 22 shared publications
Ping Zhang
Academy of Medical Sciences (GB)
21 shared publications
- Epigenomic analysis reveals a dynamic and context-specific macrophage enhancer landscape associated with innate immune activation and tolerance
- Comprehensive epigenomic profiling reveals the extent of disease-specific chromatin states and informs target discovery in ankylosing spondylitis
- Mapping the epigenomic landscape of human monocytes following innate immune activation reveals context-specific mechanisms driving endotoxin tolerance
- Mapping the epigenomic landscape of human monocytes following innate immune activation reveals context-specific mechanisms driving endotoxin tolerance
- Mapping the epigenomic landscape of human monocytes following innate immune activation reveals context-specific mechanisms driving endotoxin tolerance
Showing 5 of 21 shared publications
Gabriele Migliorini
Centre for Human Genetics (GB)
20 shared publications
- Epigenomic analysis reveals a dynamic and context-specific macrophage enhancer landscape associated with innate immune activation and tolerance
- Comprehensive epigenomic profiling reveals the extent of disease-specific chromatin states and informs target discovery in ankylosing spondylitis
- Mapping the epigenomic landscape of human monocytes following innate immune activation reveals context-specific mechanisms driving endotoxin tolerance
- Mapping the epigenomic landscape of human monocytes following innate immune activation reveals context-specific mechanisms driving endotoxin tolerance
- Mapping the epigenomic landscape of human monocytes following innate immune activation reveals context-specific mechanisms driving endotoxin tolerance
Showing 5 of 20 shared publications
Justin P. Whalley
University of Oxford (GB)
16 shared publications
- Using de novo assembly to identify structural variation of eight complex immune system gene regions
- Epigenomic analysis reveals a dynamic and context-specific macrophage enhancer landscape associated with innate immune activation and tolerance
- Mapping the epigenomic landscape of human monocytes following innate immune activation reveals context-specific mechanisms driving endotoxin tolerance
- Using <i>de novo</i> assembly to identify structural variation of complex immune system gene regions
- Mapping the epigenomic landscape of human monocytes following innate immune activation reveals context-specific mechanisms driving endotoxin tolerance
Showing 5 of 16 shared publications
Harindra E. Amarasinghe
University of Oxford (GB)
14 shared publications
- Epigenomic analysis reveals a dynamic and context-specific macrophage enhancer landscape associated with innate immune activation and tolerance
- Mapping the epigenomic landscape of human monocytes following innate immune activation reveals context-specific mechanisms driving endotoxin tolerance
- Mapping the epigenomic landscape of human monocytes following innate immune activation reveals context-specific mechanisms driving endotoxin tolerance
- Mapping the epigenomic landscape of human monocytes following innate immune activation reveals context-specific mechanisms driving endotoxin tolerance
- Additional file 9 of Mapping the epigenomic landscape of human monocytes following innate immune activation reveals context-specific mechanisms driving endotoxin tolerance
Showing 5 of 14 shared publications
Olga Mielczarek
Centre for Human Genetics (GB)
8 shared publications
- Using de novo assembly to identify structural variation of eight complex immune system gene regions
- Comprehensive epigenomic profiling reveals the extent of disease-specific chromatin states and informs target discovery in ankylosing spondylitis
- Using <i>de novo</i> assembly to identify structural variation of complex immune system gene regions
- Comprehensive epigenomic profiling reveals the extent of disease-specific chromatin states and informs target discovery in ankylosing spondylitis
- Comprehensive epigenomic profiling reveals disease-specific chromatin states and enhances therapeutic target discovery in ankylosing spondylitis
Showing 5 of 8 shared publications
Paul Bowness
Université Paris-Saclay (FR)
8 shared publications
- A blood atlas of COVID-19 defines hallmarks of disease severity and specificity
- A blood atlas of COVID-19 defines hallmarks of disease severity and specificity
- Comprehensive epigenomic profiling reveals the extent of disease-specific chromatin states and informs target discovery in ankylosing spondylitis
- Comprehensive epigenomic profiling reveals the extent of disease-specific chromatin states and informs target discovery in ankylosing spondylitis
- Comprehensive epigenomic profiling reveals disease-specific chromatin states and enhances therapeutic target discovery in ankylosing spondylitis
Showing 5 of 8 shared publications
Hai Fang
Shanghai Jiao Tong University (CN)
7 shared publications
- Epigenomic analysis reveals a dynamic and context-specific macrophage enhancer landscape associated with innate immune activation and tolerance
- Comprehensive epigenomic profiling reveals the extent of disease-specific chromatin states and informs target discovery in ankylosing spondylitis
- Comprehensive epigenomic profiling reveals the extent of disease-specific chromatin states and informs target discovery in ankylosing spondylitis
- Comprehensive epigenomic profiling reveals disease-specific chromatin states and enhances therapeutic target discovery in ankylosing spondylitis
- Comprehensive epigenomic profiling reveals disease-specific chromatin states and enhances therapeutic target discovery in ankylosing spondylitis
Showing 5 of 7 shared publications
Katie L. Burnham
Wellcome Sanger Institute (GB)
6 shared publications
- A blood atlas of COVID-19 defines hallmarks of disease severity and specificity
- A blood atlas of COVID-19 defines hallmarks of disease severity and specificity
- Constructing custom-made radiotranscriptomic signatures of vascular inflammation from routine CT angiograms: a prospective outcomes validation study in COVID-19
- Context-specific regulatory genetic variation in MTOR dampens neutrophil-T cell crosstalk in sepsis, modulating disease
- Evidence for enhancer activity in intron 1 of TNFRSF1A using CRISPR/Cas9 in human induced pluripotent stem cell-derived macrophages
Showing 5 of 6 shared publications
Félicie Costantino
Inserm (FR)
6 shared publications
- Comprehensive epigenomic profiling reveals the extent of disease-specific chromatin states and informs target discovery in ankylosing spondylitis
- Novel risk loci in LGI1-antibody encephalitis: genome-wide association study discovery and validation cohorts
- Comprehensive epigenomic profiling reveals the extent of disease-specific chromatin states and informs target discovery in ankylosing spondylitis
- Comprehensive epigenomic profiling reveals disease-specific chromatin states and enhances therapeutic target discovery in ankylosing spondylitis
- Comprehensive epigenomic profiling reveals disease-specific chromatin states and enhances therapeutic target discovery in ankylosing spondylitis
Showing 5 of 6 shared publications
Katherine S. Elliott
University of Oxford (GB)
6 shared publications
- Comprehensive epigenomic profiling reveals the extent of disease-specific chromatin states and informs target discovery in ankylosing spondylitis
- Novel risk loci in LGI1-antibody encephalitis: genome-wide association study discovery and validation cohorts
- Comprehensive epigenomic profiling reveals the extent of disease-specific chromatin states and informs target discovery in ankylosing spondylitis
- Comprehensive epigenomic profiling reveals disease-specific chromatin states and enhances therapeutic target discovery in ankylosing spondylitis
- Comprehensive epigenomic profiling reveals disease-specific chromatin states and enhances therapeutic target discovery in ankylosing spondylitis
Showing 5 of 6 shared publications
Julie Osgood
Centre for Human Genetics (GB)
6 shared publications
- Comprehensive epigenomic profiling reveals the extent of disease-specific chromatin states and informs target discovery in ankylosing spondylitis
- Comprehensive epigenomic profiling reveals the extent of disease-specific chromatin states and informs target discovery in ankylosing spondylitis
- Comprehensive epigenomic profiling reveals disease-specific chromatin states and enhances therapeutic target discovery in ankylosing spondylitis
- Comprehensive epigenomic profiling reveals disease-specific chromatin states and enhances therapeutic target discovery in ankylosing spondylitis
- Comprehensive epigenomic profiling reveals the extent of disease-specific chromatin states and informs target discovery in ankylosing spondylitis
Showing 5 of 6 shared publications
C. Cohen
Centre for Human Genetics (GB)
5 shared publications
- Comprehensive epigenomic profiling reveals the extent of disease-specific chromatin states and informs target discovery in ankylosing spondylitis
- Comprehensive epigenomic profiling reveals the extent of disease-specific chromatin states and informs target discovery in ankylosing spondylitis
- Comprehensive epigenomic profiling reveals disease-specific chromatin states and enhances therapeutic target discovery in ankylosing spondylitis
- Comprehensive epigenomic profiling reveals disease-specific chromatin states and enhances therapeutic target discovery in ankylosing spondylitis
- Comprehensive epigenomic profiling reveals the extent of disease-specific chromatin states and informs target discovery in ankylosing spondylitis
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