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Biography and Research Information
OverviewAI-generated summary
Xinyu Li's research investigates the multifaceted roles of extracellular vesicles, particularly exosomes, in the tumor microenvironment and their implications for cancer immunotherapy. This work explores how these vesicles are released, taken up by cells, and influence biological functions, with a focus on their potential clinical applications. Li's publications also address the specific mechanisms of SARS-CoV-2 infection, including spike protein-mediated membrane fusion, and the metabolic vulnerabilities of tumor cells, such as glutamine addiction, and their relationship to oncogene regulation and treatment strategies. Further research areas include the involvement of mast cells in colorectal cancer progression, angiogenesis, and lymphangiogenesis, as well as the function of extracellular vesicle PD-L1 in modulating the tumor immune microenvironment and its potential as a therapeutic target.
With a substantial publication record and high citation count, Li's work contributes to the understanding of complex biological processes related to cancer and infectious diseases. The researcher's scholarship metrics include an h-index of 42 and over 5,800 total citations across 372 publications, indicating significant impact within their research fields. Li is recognized as a highly cited researcher, signifying broad recognition for their scholarly contributions.
Metrics
- h-index: 43
- Publications: 372
- Citations: 5,893
Selected Publications
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Expanding the Genetic Code with Lysine Aminoacylation (2026)
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Genome-wide screening of antibiotic survival genes in Escherichia coli MG1655 (2026)
Collaboration Network
Top Collaborators
Xueqiang Peng
Fourth Affiliated Hospital of China Medical University (CN)
6 shared publications
- Exosomes in the hypoxic TME: from release, uptake and biofunctions to clinical applications
- Glutamine addiction in tumor cell: oncogene regulation and clinical treatment
- Tumor-derived exosomes in the cancer immune microenvironment and cancer immunotherapy
- Extracellular vesicle PD-L1 in reshaping tumor immune microenvironment: biological function and potential therapy strategies
- LINC00511 drives invasive behavior in hepatocellular carcinoma by regulating exosome secretion and invadopodia formation
Showing 5 of 6 shared publications
Shuo Yang
Fourth Affiliated Hospital of China Medical University (CN)
6 shared publications
- Exosomes in the hypoxic TME: from release, uptake and biofunctions to clinical applications
- Glutamine addiction in tumor cell: oncogene regulation and clinical treatment
- Tumor-derived exosomes in the cancer immune microenvironment and cancer immunotherapy
- Extracellular vesicle PD-L1 in reshaping tumor immune microenvironment: biological function and potential therapy strategies
- LINC00511 drives invasive behavior in hepatocellular carcinoma by regulating exosome secretion and invadopodia formation
Showing 5 of 6 shared publications
Shibo Wei
Fourth Affiliated Hospital of China Medical University (CN)
6 shared publications
- Exosomes in the hypoxic TME: from release, uptake and biofunctions to clinical applications
- Glutamine addiction in tumor cell: oncogene regulation and clinical treatment
- Tumor-derived exosomes in the cancer immune microenvironment and cancer immunotherapy
- Extracellular vesicle PD-L1 in reshaping tumor immune microenvironment: biological function and potential therapy strategies
- LINC00511 drives invasive behavior in hepatocellular carcinoma by regulating exosome secretion and invadopodia formation
Showing 5 of 6 shared publications
Liang Yang
Fourth Affiliated Hospital of China Medical University (CN)
6 shared publications
- Exosomes in the hypoxic TME: from release, uptake and biofunctions to clinical applications
- Glutamine addiction in tumor cell: oncogene regulation and clinical treatment
- Tumor-derived exosomes in the cancer immune microenvironment and cancer immunotherapy
- Extracellular vesicle PD-L1 in reshaping tumor immune microenvironment: biological function and potential therapy strategies
- LINC00511 drives invasive behavior in hepatocellular carcinoma by regulating exosome secretion and invadopodia formation
Showing 5 of 6 shared publications
Qi Pu
Tongji Hospital (CN)
5 shared publications
- Nicotinamide mononucleotide increases cell viability and restores tight junctions in high-glucose-treated human corneal epithelial cells via the SIRT1/Nrf2/HO-1 pathway
- Nicotinamide Mononucleotide Alleviates Hyperosmolarity-Induced IL-17a Secretion and Macrophage Activation in Corneal Epithelial Cells/Macrophage Co-Culture System
- Neutrophil/Lymphocyte Ratio as an Inflammatory Predictor of Dry Eye Disease: A Case-Control Study
- Association between poor sleep quality and an increased risk of dry eye disease in patients with obstructive sleep apnea syndrome
- The role of regulated necrosis in inflammation and ocular surface diseases
Hangyu Li
Fourth Affiliated Hospital of China Medical University (CN)
5 shared publications
- Glutamine addiction in tumor cell: oncogene regulation and clinical treatment
- Tumor-derived exosomes in the cancer immune microenvironment and cancer immunotherapy
- LINC00511 drives invasive behavior in hepatocellular carcinoma by regulating exosome secretion and invadopodia formation
- Hypoxia, a key factor in the immune microenvironment
- Extracellular vesicle-cell adhesion molecules in tumours: biofunctions and clinical applications
Guangpeng He
Fourth Affiliated Hospital of China Medical University (CN)
5 shared publications
- Exosomes in the hypoxic TME: from release, uptake and biofunctions to clinical applications
- Glutamine addiction in tumor cell: oncogene regulation and clinical treatment
- Tumor-derived exosomes in the cancer immune microenvironment and cancer immunotherapy
- Extracellular vesicle PD-L1 in reshaping tumor immune microenvironment: biological function and potential therapy strategies
- Extracellular vesicle-cell adhesion molecules in tumours: biofunctions and clinical applications
Jiaxing Liu
Fourth Affiliated Hospital of China Medical University (CN)
5 shared publications
- Exosomes in the hypoxic TME: from release, uptake and biofunctions to clinical applications
- Glutamine addiction in tumor cell: oncogene regulation and clinical treatment
- Tumor-derived exosomes in the cancer immune microenvironment and cancer immunotherapy
- Extracellular vesicle PD-L1 in reshaping tumor immune microenvironment: biological function and potential therapy strategies
- Extracellular vesicle-cell adhesion molecules in tumours: biofunctions and clinical applications
Chang Gao
China Medical University (CN)
4 shared publications
- Dietary Inflammatory Index and Health Outcomes: An Umbrella Review of Systematic Review and Meta-Analyses of Observational Studies
- Cruciferous vegetable consumption and multiple health outcomes: an umbrella review of 41 systematic reviews and meta-analyses of 303 observational studies
- Non-Genetic Factors and Risk of Cervical Cancer: An Umbrella Review of Systematic Reviews and Meta-Analyses of Observational Studies
- Dietary protein and multiple health outcomes: An umbrella review of systematic reviews and meta-analyses of observational studies
Yuhong Zhao
China Medical University (CN)
4 shared publications
- Dietary Inflammatory Index and Health Outcomes: An Umbrella Review of Systematic Review and Meta-Analyses of Observational Studies
- Cruciferous vegetable consumption and multiple health outcomes: an umbrella review of 41 systematic reviews and meta-analyses of 303 observational studies
- Non-Genetic Factors and Risk of Cervical Cancer: An Umbrella Review of Systematic Reviews and Meta-Analyses of Observational Studies
- Dietary protein and multiple health outcomes: An umbrella review of systematic reviews and meta-analyses of observational studies
Qi‐Jun Wu
Shanghai Clinical Research Center (CN)
4 shared publications
- Dietary Inflammatory Index and Health Outcomes: An Umbrella Review of Systematic Review and Meta-Analyses of Observational Studies
- Cruciferous vegetable consumption and multiple health outcomes: an umbrella review of 41 systematic reviews and meta-analyses of 303 observational studies
- Non-Genetic Factors and Risk of Cervical Cancer: An Umbrella Review of Systematic Reviews and Meta-Analyses of Observational Studies
- Dietary protein and multiple health outcomes: An umbrella review of systematic reviews and meta-analyses of observational studies
Qing Fan
Fourth Affiliated Hospital of China Medical University (CN)
4 shared publications
- Exosomes in the hypoxic TME: from release, uptake and biofunctions to clinical applications
- Tumor-derived exosomes in the cancer immune microenvironment and cancer immunotherapy
- Extracellular vesicle PD-L1 in reshaping tumor immune microenvironment: biological function and potential therapy strategies
- LINC00511 drives invasive behavior in hepatocellular carcinoma by regulating exosome secretion and invadopodia formation
Fang-Hua Liu
Shanghai Clinical Research Center (CN)
3 shared publications
- Dietary Inflammatory Index and Health Outcomes: An Umbrella Review of Systematic Review and Meta-Analyses of Observational Studies
- Cruciferous vegetable consumption and multiple health outcomes: an umbrella review of 41 systematic reviews and meta-analyses of 303 observational studies
- Non-Genetic Factors and Risk of Cervical Cancer: An Umbrella Review of Systematic Reviews and Meta-Analyses of Observational Studies
Ting‐Ting Gong
China Medical University (CN)
3 shared publications
- Dietary Inflammatory Index and Health Outcomes: An Umbrella Review of Systematic Review and Meta-Analyses of Observational Studies
- Cruciferous vegetable consumption and multiple health outcomes: an umbrella review of 41 systematic reviews and meta-analyses of 303 observational studies
- Non-Genetic Factors and Risk of Cervical Cancer: An Umbrella Review of Systematic Reviews and Meta-Analyses of Observational Studies
Mingyao Huang
China Medical University (CN)
3 shared publications
- Exosomes in the hypoxic TME: from release, uptake and biofunctions to clinical applications
- Extracellular vesicle PD-L1 in reshaping tumor immune microenvironment: biological function and potential therapy strategies
- LINC00511 drives invasive behavior in hepatocellular carcinoma by regulating exosome secretion and invadopodia formation
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