Match tier
Listed
Presence
Current · Arkansas
Last published
2026
Sources
OpenAlex · ORCID
Refreshed
2026-10-05
C
Clark R. Sims
Assistant Staff Scientist
Also affiliated: Baylor College of Medicine (2016); University of Arkansas Medical Center (2022); Arkansas Children's Nutrition Center (2013–2026); Texas Children's Hospital (2016); Arkansas Children's Research Institute (2024)
Pediatrics, College of Medicine
16 h-index
63 pubs
853 cited
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Clark Sims studies the relationship between maternal health, particularly overweight and obesity, and infant development. His research investigates how factors such as maternal diet, body composition, and human milk composition influence infant growth, gut microbiome, and skeletal development. Sims has received funding for projects examining the associations between maternal obesity and offspring gut microbiome in the first year of life, and the impact of maternal diet and body composition on gut microbial ecology during pregnancy. His work also explores the effects of human milk oligosaccharides and branched-chain amino acids on infant growth, and how breastfeeding duration modifies the association between maternal weight status and offspring dietary palmitate oxidation. Sims has also investigated the association between per- and polyfluoroalkyl substances (PFAS) during pregnancy and maternal cardiometabolic outcomes.
Metrics
- h-index: 16
- Publications: 63
- Citations: 853
Positions
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Associate Staff Scientist 2023–presentUniversity of Arkansas for Medical Sciences Arkansas Children's Nutrition Center / Department of Pediatrics ORCID
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Assistant Staff Scientist 2020–presentUniversity of Arkansas for Medical Sciences Pediatrics, College of Medicine Institutional directory
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Senior Research Associate 2018–2020Arkansas Children's Hospital Arkansas Children's Nutrition Center ORCID
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Postdoctoral Fellow 2016–2018University of Arkansas for Medical Sciences Arkansas Children's Nutrition Center / Department of Pediatrics ORCID
Selected Publications
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Circulating short- and medium-chain fatty acids in pregnancy and associations with maternal and infant metabolism, inflammation, and body composition (2026)
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Characterizing Human Milk RNA Degradation Over Time to Optimize Storage of Human Milk for RNA Quality (2026)
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Promoting Breastfeeding Among Latina Women in a Community Pediatric Clinic (2025)
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The Effect of an Exercise Program on Maternal Health and Birth Outcomes in Sedentary Pregnant Participants with Obesity: Randomized Controlled Trial (2025)
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Sex-Dependent Relationships Between PFAS and Placental Transcriptomics Identified by Weighted Gene Co-Expression Analysis (2025)
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Individual and mixture associations of placental per- and polyfluoroalkyl substance with neurodevelopment at 12 and 24 months of age (2025)
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Prenatal Polyphenol Intake During Late Pregnancy Is Positively Associated With Academic and IQ Scores in School-Age Children (2025)
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Breastfeeding beyond infancy supports adequate growth, development, and nutritional intake (2025)
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Individual and mixtures of PFAS during pregnancy are associated with maternal cardiometabolic outcomes during pregnancy (2025)
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Dietary modulation of human milk bioactives is associated with maternal FUT2 secretor phenotype: an exploratory analysis of carotenoids and polyphenol metabolites (2024)
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Exploring the relationship between child temperament, maternal psychiatric symptoms, family environment and infant feeding (2024)
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Maternal immune cell gene expression associates with maternal gut microbiome, milk composition and infant gut microbiome (2024)
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Childhood cardiometabolic risk factors associated with the perinatal environment of the maternal–paternal–child triad (2024)
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PFAS exposures during pregnancy are associated with infant growth and development during the first 2 years of life (2024)
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PFAS exposure during pregnancy is associated with maternal cardiometabolic and birth outcomes (2024)
Grants & Funding
As listed on this researcher's institutional profile.
- Renal microcirculatory failure in a rat pup model of pediatric sepsis American Heart Association (SouthWest Affiliate) Principal Investigator
- Targeting renal perfusion and mitochondrial oxidants in a model of infant sepsis NIH Principal Investigator
Collaboration Network
Top Collaborators
Aline Andres
Arkansas Children's Nutrition Center
36 shared publications
In database
- Human Milk Oligosaccharide Concentrations and Infant Intakes Are Associated with Maternal Overweight and Obesity and Predict Infant Growth
- Obesity Modulates Inflammation and Lipid Metabolism Oocyte Gene Expression: A Single-Cell Transcriptome Perspective
- Exercise-induced 3′-sialyllactose in breast milk is a critical mediator to improve metabolic health and cardiac function in mouse offspring
- Associations between maternal obesity and offspring gut microbiome in the first year of life
- Associations between Maternal Diet, Body Composition and Gut Microbial Ecology in Pregnancy
Showing 5 of 36 shared publications
Kartik Shankar
Southern Plains Agricultural Research Center (US)
13 shared publications
- Obesity Modulates Inflammation and Lipid Metabolism Oocyte Gene Expression: A Single-Cell Transcriptome Perspective
- Associations between maternal obesity and offspring gut microbiome in the first year of life
- Associations between Maternal Diet, Body Composition and Gut Microbial Ecology in Pregnancy
- Parental adiposity differentially associates with newborn body composition
- Maternal Adiposity is Associated with Fat Mass Accretion in Female but not Male Offspring During the First 2 Years of Life
Showing 5 of 13 shared publications
Donald Turner
Arkansas Children's Nutrition Center (US)
11 shared publications
- Associations between maternal obesity and offspring gut microbiome in the first year of life
- Associations between Maternal Diet, Body Composition and Gut Microbial Ecology in Pregnancy
- A Mediterranean diet plan in lactating women with obesity reduces maternal energy intake and modulates human milk composition – a feasibility study
- Individual and mixtures of PFAS during pregnancy are associated with maternal cardiometabolic outcomes during pregnancy
- The Effect of an Exercise Program on Maternal Health and Birth Outcomes in Sedentary Pregnant Participants with Obesity: Randomized Controlled Trial
Showing 5 of 11 shared publications
Sarah Sobik
Arkansas Children's Hospital
9 shared publications
In database
- Parental adiposity differentially associates with newborn body composition
- Maternal Adiposity is Associated with Fat Mass Accretion in Female but not Male Offspring During the First 2 Years of Life
- A Mediterranean diet plan in lactating women with obesity reduces maternal energy intake and modulates human milk composition – a feasibility study
- The Impact of Excessive Weight on Breastfeeding Intention, Initiation, and Duration
- Childhood cardiometabolic risk factors associated with the perinatal environment of the maternal–paternal–child triad
Showing 5 of 9 shared publications
Elisabet Børsheim
Arkansas Children's Hospital
8 shared publications
In database
- Parental adiposity differentially associates with newborn body composition
- Maternal Adiposity is Associated with Fat Mass Accretion in Female but not Male Offspring During the First 2 Years of Life
- Infant intakes of human milk branched chain amino acids are negatively associated with infant growth and influenced by maternal body mass index
- Breastfeeding duration modifies the association between maternal weight status and offspring dietary palmitate oxidation
- The Effect of an Exercise Program on Maternal Health and Birth Outcomes in Sedentary Pregnant Participants with Obesity: Randomized Controlled Trial
Showing 5 of 8 shared publications
Meghan Crimmins
University of Minnesota (US)
8 shared publications
- A Mediterranean diet plan in lactating women with obesity reduces maternal energy intake and modulates human milk composition – a feasibility study
- The Impact of Excessive Weight on Breastfeeding Intention, Initiation, and Duration
- Dietary modulation of human milk bioactives is associated with maternal FUT2 secretor phenotype: an exploratory analysis of carotenoids and polyphenol metabolites
- Effect of a dietary and exercise intervention in women with overweight and obesity undergoing fertility treatments: protocol for a randomized controlled trial
- Associations Between Maternal Physical Activity, Maternal Lipid Levels, and Infant Anthropometric Outcomes at Two Weeks of Age
Showing 5 of 8 shared publications
Meghan L. Ruebel
Arkansas Children's Nutrition Center (US)
7 shared publications
- Obesity Modulates Inflammation and Lipid Metabolism Oocyte Gene Expression: A Single-Cell Transcriptome Perspective
- Associations between maternal obesity and offspring gut microbiome in the first year of life
- Associations between Maternal Diet, Body Composition and Gut Microbial Ecology in Pregnancy
- Parental adiposity differentially associates with newborn body composition
- Maternal Adiposity is Associated with Fat Mass Accretion in Female but not Male Offspring During the First 2 Years of Life
Showing 5 of 7 shared publications
Lars Bode
University of California San Diego (US)
7 shared publications
- Human Milk Oligosaccharide Concentrations and Infant Intakes Are Associated with Maternal Overweight and Obesity and Predict Infant Growth
- Exercise-induced 3′-sialyllactose in breast milk is a critical mediator to improve metabolic health and cardiac function in mouse offspring
- Associations between maternal obesity and offspring gut microbiome in the first year of life
- A Mediterranean diet plan in lactating women with obesity reduces maternal energy intake and modulates human milk composition – a feasibility study
- Maternal immune cell gene expression associates with maternal gut microbiome, milk composition and infant gut microbiome
Showing 5 of 7 shared publications
Thomas M. Badger
Arkansas Children's Hospital
6 shared publications
In database
- Obesity Modulates Inflammation and Lipid Metabolism Oocyte Gene Expression: A Single-Cell Transcriptome Perspective
- Loss of Functional NADPH Oxidase 2 Protects Against Alcohol‐Induced Bone Resorption in Female p47phox −/− Mice
- Parental adiposity differentially associates with newborn body composition
- Developmental assessments during the first 5 years of life in infants fed breast milk, cow's milk formula, or soy formula
- Early Infant Formula Feeding Impacts Urinary Metabolite Profile at 3 Months of Age
Showing 5 of 6 shared publications
Audrey Martinez
Arkansas Children's Nutrition Center
6 shared publications
In database
- A Mediterranean diet plan in lactating women with obesity reduces maternal energy intake and modulates human milk composition – a feasibility study
- The Effect of an Exercise Program on Maternal Health and Birth Outcomes in Sedentary Pregnant Participants with Obesity: Randomized Controlled Trial
- Dietary modulation of human milk bioactives is associated with maternal FUT2 secretor phenotype: an exploratory analysis of carotenoids and polyphenol metabolites
- Effect of a dietary and exercise intervention in women with overweight and obesity undergoing fertility treatments: protocol for a randomized controlled trial
- Maternal FUT2 Secretor Phenotype Is Associated With Human Milk Oligosaccharides and Polyphenol Metabolites Following a Mediterranean Dietary Intervention: A Pilot Study
Showing 5 of 6 shared publications
Todd M. Everson
Emory University (US)
6 shared publications
- Individual and mixtures of PFAS during pregnancy are associated with maternal cardiometabolic outcomes during pregnancy
- Sex-Dependent Relationships Between PFAS and Placental Transcriptomics Identified by Weighted Gene Co-Expression Analysis
- Pfas Exposure During Pregnancy is Associated with Maternal Cardiometabolic and Birth Outcomes
- PFAS exposure during pregnancy is associated with maternal cardiometabolic and birth outcomes
- PFAS exposures during pregnancy are associated with infant growth and development during the first 2 years of life
Showing 5 of 6 shared publications
Philip R. Mayeux
University of Arkansas for Medical Sciences
5 shared publications
In database
- Pharmacologic Targeting of Sphingosine-1-Phosphate Receptor 1 Improves the Renal Microcirculation during Sepsis in the Mouse
- Targeting mitochondrial oxidants may facilitate recovery of renal function during infant sepsis
- Rolipram Improves Outcome in a Rat Model of Infant Sepsis-Induced Cardiorenal Syndrome
- Preclinical Evaluation of the Phosphodiesterase‐4 Inhibitor, Rolipram, in an Infant Model of Sepsis‐Induced Cardiorenal Syndrome
- Development of Renal Dysfunction in an Infant Model of Polymicrobial Sepsis
Eva C. Diaz
Arkansas Children's Nutrition Center
5 shared publications
In database
- Parental adiposity differentially associates with newborn body composition
- Maternal Adiposity is Associated with Fat Mass Accretion in Female but not Male Offspring During the First 2 Years of Life
- Breastfeeding duration modifies the association between maternal weight status and offspring dietary palmitate oxidation
- The Effect of an Exercise Program on Maternal Health and Birth Outcomes in Sedentary Pregnant Participants with Obesity: Randomized Controlled Trial
- Childhood cardiometabolic risk factors associated with the perinatal environment of the maternal–paternal–child triad
Jayne Bellando
Arkansas Children's Nutrition Center
5 shared publications
In database
- Developmental assessments during the first 5 years of life in infants fed breast milk, cow's milk formula, or soy formula
- The Effect of an Exercise Program on Maternal Health and Birth Outcomes in Sedentary Pregnant Participants with Obesity: Randomized Controlled Trial
- The Impact of Excessive Weight on Breastfeeding Intention, Initiation, and Duration
- Prenatal Polyphenol Intake During Late Pregnancy Is Positively Associated With Academic and IQ Scores in School-Age Children
- Individual and mixture associations of placental per- and polyfluoroalkyl substance with neurodevelopment at 12 and 24 months of age
David Williams
Arkansas Children's Nutrition Center (US)
5 shared publications
- Breastfeeding duration modifies the association between maternal weight status and offspring dietary palmitate oxidation
- Childhood cardiometabolic risk factors associated with the perinatal environment of the maternal–paternal–child triad
- Dietary modulation of human milk bioactives is associated with maternal FUT2 secretor phenotype: an exploratory analysis of carotenoids and polyphenol metabolites
- Breastfeeding beyond infancy supports adequate growth, development, and nutritional intake
- Promoting Breastfeeding Among Latina Women in a Community Pediatric Clinic
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