Biography and Research Information
OverviewAI-generated summary
Dan Li's research focuses on the application of high-throughput sequencing technologies and computational analysis in medical research, particularly in the fields of oncology and developmental biology. His work includes evaluating the analytical validity of circulating tumor DNA sequencing assays for precision oncology and augmenting precision medicine through targeted RNA-Seq detection of expressed mutations. Li has also investigated gene regulation perturbations during neural system development in the context of autism spectrum disorder.
Further research extends to the analysis of tumor mutational burden estimation using targeted panel sequencing and the translation of liver microphysiological systems for regulatory applications via single-cell RNA-sequencing and spatial transcriptomics. He has also explored treatment plan complexity for quality assurance in stereotactic volumetric modulated arc therapy. Li collaborates with researchers from institutions including the National Center for Toxicological Research, the University of Arkansas for Medical Sciences, and the University of Arkansas at Little Rock.
Metrics
- h-index: 4
- Publications: 12
- Citations: 286
Selected Publications
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Augmenting precision medicine via targeted RNA-Seq detection of expressed mutations (2025)
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Assessments of tumor mutational burden estimation by targeted panel sequencing: A comprehensive simulation analysis (2023)
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Single-cell RNA-sequencing and subcellular spatial transcriptomics facilitate the translation of liver microphysiological systems for regulatory application (2023)
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Transcriptomic Response of Human Nosocomial Pathogen Pseudomonas aeruginosa Biofilms Following Continuous Exposure to Antibiotic-Impregnated Catheters (2022)
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Gene Regulation Analysis Reveals Perturbations of Autism Spectrum Disorder during Neural System Development (2021)
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Evaluating the analytical validity of circulating tumor DNA sequencing assays for precision oncology (2021)
Collaboration Network
Top Collaborators
Binsheng Gong
6 shared publications
In database
- Evaluating the analytical validity of circulating tumor DNA sequencing assays for precision oncology
- Augmenting precision medicine via targeted RNA-Seq detection of expressed mutations
- Single-cell RNA-sequencing and subcellular spatial transcriptomics facilitate the translation of liver microphysiological systems for regulatory application
- Additional file 3 of Deep oncopanel sequencing reveals within block position-dependent quality degradation in FFPE processed samples
- Additional file 2 of Deep oncopanel sequencing reveals within block position-dependent quality degradation in FFPE processed samples
Showing 5 of 6 shared publications
Rebecca Kusko
5 shared publications
- Evaluating the analytical validity of circulating tumor DNA sequencing assays for precision oncology
- Augmenting precision medicine via targeted RNA-Seq detection of expressed mutations
- Additional file 3 of Deep oncopanel sequencing reveals within block position-dependent quality degradation in FFPE processed samples
- Additional file 2 of Deep oncopanel sequencing reveals within block position-dependent quality degradation in FFPE processed samples
- Evaluating the analytical validity of circulating tumor DNA sequencing assays for precision oncology
Joshua Xu
5 shared publications
In database
- Gene Regulation Analysis Reveals Perturbations of Autism Spectrum Disorder during Neural System Development
- Single-cell RNA-sequencing and subcellular spatial transcriptomics facilitate the translation of liver microphysiological systems for regulatory application
- Assessments of tumor mutational burden estimation by targeted panel sequencing: A comprehensive simulation analysis
- Transcriptomic Response of Human Nosocomial Pathogen Pseudomonas aeruginosa Biofilms Following Continuous Exposure to Antibiotic-Impregnated Catheters
- Evaluating the analytical validity of circulating tumor DNA sequencing assays for precision oncology
Natalia Novoradovskaya
Agilent Technologies (United States) (US)
4 shared publications
- Evaluating the analytical validity of circulating tumor DNA sequencing assays for precision oncology
- Augmenting precision medicine via targeted RNA-Seq detection of expressed mutations
- Additional file 3 of Deep oncopanel sequencing reveals within block position-dependent quality degradation in FFPE processed samples
- Additional file 2 of Deep oncopanel sequencing reveals within block position-dependent quality degradation in FFPE processed samples
Jennifer S. LoCoco
Illumina (United States) (US)
3 shared publications
- Evaluating the analytical validity of circulating tumor DNA sequencing assays for precision oncology
- Additional file 3 of Deep oncopanel sequencing reveals within block position-dependent quality degradation in FFPE processed samples
- Additional file 2 of Deep oncopanel sequencing reveals within block position-dependent quality degradation in FFPE processed samples
Wendell Jones
3 shared publications
- Evaluating the analytical validity of circulating tumor DNA sequencing assays for precision oncology
- Augmenting precision medicine via targeted RNA-Seq detection of expressed mutations
- Evaluating the analytical validity of circulating tumor DNA sequencing assays for precision oncology
Fujun Qiu
Burning Rock Biotech (China) (CN)
3 shared publications
- Evaluating the analytical validity of circulating tumor DNA sequencing assays for precision oncology
- Additional file 3 of Deep oncopanel sequencing reveals within block position-dependent quality degradation in FFPE processed samples
- Additional file 2 of Deep oncopanel sequencing reveals within block position-dependent quality degradation in FFPE processed samples
Robert Sebra
Icahn School of Medicine at Mount Sinai (US)
3 shared publications
- Evaluating the analytical validity of circulating tumor DNA sequencing assays for precision oncology
- Additional file 3 of Deep oncopanel sequencing reveals within block position-dependent quality degradation in FFPE processed samples
- Additional file 2 of Deep oncopanel sequencing reveals within block position-dependent quality degradation in FFPE processed samples
Daniel Stetson
AstraZeneca (United States) (US)
3 shared publications
- Evaluating the analytical validity of circulating tumor DNA sequencing assays for precision oncology
- Additional file 3 of Deep oncopanel sequencing reveals within block position-dependent quality degradation in FFPE processed samples
- Additional file 2 of Deep oncopanel sequencing reveals within block position-dependent quality degradation in FFPE processed samples
Hanane Arib
3 shared publications
- Additional file 3 of Deep oncopanel sequencing reveals within block position-dependent quality degradation in FFPE processed samples
- Additional file 2 of Deep oncopanel sequencing reveals within block position-dependent quality degradation in FFPE processed samples
- Evaluating the analytical validity of circulating tumor DNA sequencing assays for precision oncology
Melissa Smith
3 shared publications
- Additional file 3 of Deep oncopanel sequencing reveals within block position-dependent quality degradation in FFPE processed samples
- Additional file 2 of Deep oncopanel sequencing reveals within block position-dependent quality degradation in FFPE processed samples
- Evaluating the analytical validity of circulating tumor DNA sequencing assays for precision oncology
Nikola Tom
3 shared publications
- Additional file 3 of Deep oncopanel sequencing reveals within block position-dependent quality degradation in FFPE processed samples
- Additional file 2 of Deep oncopanel sequencing reveals within block position-dependent quality degradation in FFPE processed samples
- Evaluating the analytical validity of circulating tumor DNA sequencing assays for precision oncology
Todd Richmond
Computational Physics (United States) (US)
2 shared publications
- Evaluating the analytical validity of circulating tumor DNA sequencing assays for precision oncology
- Augmenting precision medicine via targeted RNA-Seq detection of expressed mutations
Jeoffrey Schageman
2 shared publications
- Evaluating the analytical validity of circulating tumor DNA sequencing assays for precision oncology
- Evaluating the analytical validity of circulating tumor DNA sequencing assays for precision oncology
James C. Willey
University of Toledo (US)
2 shared publications
- Evaluating the analytical validity of circulating tumor DNA sequencing assays for precision oncology
- Augmenting precision medicine via targeted RNA-Seq detection of expressed mutations
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