Biography and Research Information
OverviewAI-generated summary
David M. Parham's research focuses on the pathological diagnosis and molecular characterization of pediatric tumors, particularly sarcomas. His work has contributed to understanding the genetic underpinnings of these diseases, with recent publications investigating gene fusions in mesenchymal tumors and the role of TP53 variants in anaplastic rhabdomyosarcoma. He has also examined the diagnostic and therapeutic implications of advanced molecular methods in rhabdomyosarcoma and the pathological diagnosis of pediatric soft tissue tumors in the era of molecular medicine.
Parham's research extends to other pediatric malignancies, including embryonal sarcoma of the liver and Sertoli-Leydig cell tumors of the ovary. His investigations have also addressed the clinical aspects of these diseases, such as lymph node metastasis in non-rhabdomyosarcoma soft tissue sarcomas. His extensive publication record and high citation count indicate significant contributions to the field of pediatric oncology pathology.
Metrics
- h-index: 81
- Publications: 464
- Citations: 21,144
Selected Publications
-
Pediatric Embryonal Rhabdomyosarcoma: An Integrated Study of Clinicopathological Features, Pan-cancer Targeted Next-generation Sequencing, and Chromosomal Microarray Analysis from a Single Institution (2025)
Collaboration Network
Top Collaborators
Douglas S. Hawkins
Cancer Research Center (US)
6 shared publications
- <i>TP53</i> germline pathogenic variant frequency in anaplastic rhabdomyosarcoma: A Children's Oncology Group report
- TP53 Germline Pathogenic Variant Frequency in Anaplastic Rhabdomyosarcoma: A Children’s Oncology Group Report
- Supplementary Figures 1 - 5, Tables 1 - 9 from A Novel Algorithm for Simplification of Complex Gene Classifiers in Cancer
- Supplementary Figures 1 - 5, Tables 1 - 9 from A Novel Algorithm for Simplification of Complex Gene Classifiers in Cancer
- Data from A Novel Algorithm for Simplification of Complex Gene Classifiers in Cancer
Showing 5 of 6 shared publications
Erin R. Rudzinski
Seattle Children's Hospital (US)
5 shared publications
- <scp><i>FGFR1</i></scp> gene fusions in a subset of pediatric mesenchymal tumors: Expanding the genetic spectrum of tumors sharing histologic overlap with infantile fibrosarcoma and “<scp><i>NTRK</i></scp>‐rearranged” spindle cell neoplasms
- The Pathologic Diagnosis of Pediatric Soft Tissue Tumors in the Era of Molecular Medicine: The Sarcoma Pediatric Pathology Research Interest Group Perspective
- <i>TP53</i> germline pathogenic variant frequency in anaplastic rhabdomyosarcoma: A Children's Oncology Group report
- TP53 Germline Pathogenic Variant Frequency in Anaplastic Rhabdomyosarcoma: A Children’s Oncology Group Report
- Loss of H3K27me3 Is Not Specific to Malignant Triton Tumor: Immunohistochemical Analysis of 23 Cases of Embryonal Rhabdomyosarcoma
Raphael A. Wilson
4 shared publications
- Supplementary Figures 1 - 5, Tables 1 - 9 from A Novel Algorithm for Simplification of Complex Gene Classifiers in Cancer
- Supplementary Figures 1 - 5, Tables 1 - 9 from A Novel Algorithm for Simplification of Complex Gene Classifiers in Cancer
- Data from A Novel Algorithm for Simplification of Complex Gene Classifiers in Cancer
- Data from A Novel Algorithm for Simplification of Complex Gene Classifiers in Cancer
Ling Teng
4 shared publications
- Supplementary Figures 1 - 5, Tables 1 - 9 from A Novel Algorithm for Simplification of Complex Gene Classifiers in Cancer
- Supplementary Figures 1 - 5, Tables 1 - 9 from A Novel Algorithm for Simplification of Complex Gene Classifiers in Cancer
- Data from A Novel Algorithm for Simplification of Complex Gene Classifiers in Cancer
- Data from A Novel Algorithm for Simplification of Complex Gene Classifiers in Cancer
Karen M. Bachmeyer
4 shared publications
- Supplementary Figures 1 - 5, Tables 1 - 9 from A Novel Algorithm for Simplification of Complex Gene Classifiers in Cancer
- Supplementary Figures 1 - 5, Tables 1 - 9 from A Novel Algorithm for Simplification of Complex Gene Classifiers in Cancer
- Data from A Novel Algorithm for Simplification of Complex Gene Classifiers in Cancer
- Data from A Novel Algorithm for Simplification of Complex Gene Classifiers in Cancer
Mei Lin Z. Bissonnette
4 shared publications
- Supplementary Figures 1 - 5, Tables 1 - 9 from A Novel Algorithm for Simplification of Complex Gene Classifiers in Cancer
- Supplementary Figures 1 - 5, Tables 1 - 9 from A Novel Algorithm for Simplification of Complex Gene Classifiers in Cancer
- Data from A Novel Algorithm for Simplification of Complex Gene Classifiers in Cancer
- Data from A Novel Algorithm for Simplification of Complex Gene Classifiers in Cancer
Aliya N. Husain
4 shared publications
- Supplementary Figures 1 - 5, Tables 1 - 9 from A Novel Algorithm for Simplification of Complex Gene Classifiers in Cancer
- Supplementary Figures 1 - 5, Tables 1 - 9 from A Novel Algorithm for Simplification of Complex Gene Classifiers in Cancer
- Data from A Novel Algorithm for Simplification of Complex Gene Classifiers in Cancer
- Data from A Novel Algorithm for Simplification of Complex Gene Classifiers in Cancer
Timothy J. Triche
4 shared publications
- Supplementary Figures 1 - 5, Tables 1 - 9 from A Novel Algorithm for Simplification of Complex Gene Classifiers in Cancer
- Supplementary Figures 1 - 5, Tables 1 - 9 from A Novel Algorithm for Simplification of Complex Gene Classifiers in Cancer
- Data from A Novel Algorithm for Simplification of Complex Gene Classifiers in Cancer
- Data from A Novel Algorithm for Simplification of Complex Gene Classifiers in Cancer
Michele R. Wing
4 shared publications
- Supplementary Figures 1 - 5, Tables 1 - 9 from A Novel Algorithm for Simplification of Complex Gene Classifiers in Cancer
- Supplementary Figures 1 - 5, Tables 1 - 9 from A Novel Algorithm for Simplification of Complex Gene Classifiers in Cancer
- Data from A Novel Algorithm for Simplification of Complex Gene Classifiers in Cancer
- Data from A Novel Algorithm for Simplification of Complex Gene Classifiers in Cancer
Julie M. Gastier-Foster
4 shared publications
- Supplementary Figures 1 - 5, Tables 1 - 9 from A Novel Algorithm for Simplification of Complex Gene Classifiers in Cancer
- Supplementary Figures 1 - 5, Tables 1 - 9 from A Novel Algorithm for Simplification of Complex Gene Classifiers in Cancer
- Data from A Novel Algorithm for Simplification of Complex Gene Classifiers in Cancer
- Data from A Novel Algorithm for Simplification of Complex Gene Classifiers in Cancer
Frederic G. Barr
4 shared publications
- Supplementary Figures 1 - 5, Tables 1 - 9 from A Novel Algorithm for Simplification of Complex Gene Classifiers in Cancer
- Supplementary Figures 1 - 5, Tables 1 - 9 from A Novel Algorithm for Simplification of Complex Gene Classifiers in Cancer
- Data from A Novel Algorithm for Simplification of Complex Gene Classifiers in Cancer
- Data from A Novel Algorithm for Simplification of Complex Gene Classifiers in Cancer
Stephen X. Skapek
4 shared publications
- Supplementary Figures 1 - 5, Tables 1 - 9 from A Novel Algorithm for Simplification of Complex Gene Classifiers in Cancer
- Supplementary Figures 1 - 5, Tables 1 - 9 from A Novel Algorithm for Simplification of Complex Gene Classifiers in Cancer
- Data from A Novel Algorithm for Simplification of Complex Gene Classifiers in Cancer
- Data from A Novel Algorithm for Simplification of Complex Gene Classifiers in Cancer
Samuel L. Volchenboum
4 shared publications
- Supplementary Figures 1 - 5, Tables 1 - 9 from A Novel Algorithm for Simplification of Complex Gene Classifiers in Cancer
- Supplementary Figures 1 - 5, Tables 1 - 9 from A Novel Algorithm for Simplification of Complex Gene Classifiers in Cancer
- Data from A Novel Algorithm for Simplification of Complex Gene Classifiers in Cancer
- Data from A Novel Algorithm for Simplification of Complex Gene Classifiers in Cancer
Petros Giannikopoulos
University of California, Berkeley (US)
3 shared publications
- Rhabdomyosarcoma: How Advanced Molecular Methods Are Shaping the Diagnostic and Therapeutic Paradigm
- Rhabdomyosarcoma: From Obscurity to Clarity in Diagnosis … But With Ongoing Challenges in Management: The Farber-Landing Lecture of 2020
- Pediatric Sarcomas: The Next Generation of Molecular Studies
Sheri L. Spunt
Stanford University (US)
3 shared publications
- Lymph node metastases in paediatric and young adult patients with non-rhabdomyosarcoma soft tissue sarcoma (NRSTS): Findings from Children's Oncology Group (COG) study ARST0332
- The Pathologic Diagnosis of Pediatric Soft Tissue Tumors in the Era of Molecular Medicine: The Sarcoma Pediatric Pathology Research Interest Group Perspective
- Embryonal sarcoma of the liver in pediatric and young adult patients: A report from Children’s Oncology Group study ARST0332
Similar Researchers
Based on overlapping research topics
Matthew V Steliga
University of Arkansas for Medical Sciences
Cancer Genomics and Diagnostics
Disease Mechanisms Research
Molecular Biology Techniques and Applications
Toluwanimi Ogundipe
University of Arkansas at Fayetteville
Disease Mechanisms Research
Molecular Biology Techniques and Applications
Cancer Cells and Metastasis
Saradhi Mallampati
University of Arkansas for Medical Sciences
Cancer Genomics and Diagnostics
Child and Adolescent Health
Molecular Biology Techniques and Applications
TamekaA Bailey
University of Arkansas at Fayetteville
Disease Mechanisms Research
Molecular Biology Techniques and Applications
Cancer Cells and Metastasis
Meei Liu
University of Arkansas for Medical Sciences
Cancer Genomics and Diagnostics
Disease Mechanisms Research
Molecular Biology Techniques and Applications
Veronica M. Raney
University of Arkansas for Medical Sciences
Disease Mechanisms Research
Child and Adolescent Health
Molecular Biology Techniques and Applications