Horace Jack Spencer
statistician
Also affiliated: City College of New York (1967); Arkansas Children's Hospital (1997); Loyola University Medical Center (1979); United States Department of Veterans Affairs (1962–1994); University of Kentucky (2009); Henry Ford Health (1997–1999); City University of New York (1967); Loyola University Chicago (1978–1979); University of Utah (1989); AdventHealth Orlando (2024); University of Arkansas Medical Center (2004–2016); Veterans Health Administration (1984–1988); Haukeland University Hospital (2017); Edward Hines, Jr. VA Hospital (1964–1994); Baylor University Medical Center (2016); Henry Ford Hospital (1997–1999); University of Rochester Medicine (2006); Central Arkansas Veterans Healthcare System (2001–2013); John L. McClellan Memorial Veterans Hospital (2007); Bassett Medical Center (1969); Loyola Medicine (1979); Arkansas Department of Health (1999); University of Bergen (2017); Case Western Reserve University (1997–1998)
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Horace J. Spencer is a statistician at the University of Arkansas for Medical Sciences with a distinguished publication record, evidenced by an h-index of 51 and over 8,760 citations across 288 publications. His recent research spans several medical domains, including the short-term safety of acetaminophen in patients with cirrhosis, laboratory values and end-organ effects in primary hyperparathyroidism, and the feasibility of outpatient stem cell transplantation for multiple myeloma. Spencer has also investigated the expansion of human papillomavirus-specific T cells in therapeutic vaccine recipients, the accumulation of Staphylococcus aureus virulence factors in specific mutants, and the relationship between dopamine response and motor function in Parkinson's disease. His work further extends to the impact of the COVID-19 pandemic on cancer staging for head and neck cancer patients and determinants for thyroid hormone replacement therapy in subclinical hypothyroidism.
Metrics
- h-index: 48
- Publications: 259
- Citations: 7,687
Positions
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statistician 1996–presentUniversity of Arkansas for Medical Sciences Biostatistics ORCID
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statistician 1992–1996Henry Ford Health Sciences Center Biostatistics ORCID
Selected Publications
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Comparing a Guideline-Based Mobile Health Intervention Versus Usual Care for High-Risk Adolescents With Asthma: Protocol of a Randomized Controlled Trial (2025)
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Plasma levels of anti phosphocholine IgM antibodies are negatively correlated with bone mineral density in humans (2025)
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A Predictive Model for Graves’ Disease Recurrence After Antithyroid Drug Therapy: A Retrospective Multicenter Cohort Study (2024)
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(009) THE PENIS SCORE AND PROPOSAL OF THE PACKAGE CHECKLIST: A META-EPIDEMIOLOGIC STUDY ON PENILE AMPUTATION AND REPLANTATION (2024)
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Four-dimensional computed tomography and ultrasonography for prediction of pathological parathyroid location: a retrospective review of a single surgeon’s patients at a single institution (2024)
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Feasibility of regional center telehealth visits utilizing a rural research network in people with Parkinson’s disease (2024)
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Access to Digital Technology among Teens with Asthma: A Barrier or Facilitator of Mobile Health Interventions? (2024)
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Development and implementation of the frog-in-maze game to study upper limb movement in people with Parkinson’s disease (2023)
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Comparative evaluation of small molecules reported to be inhibitors of Staphylococcus aureus biofilm formation (2023)
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THU664 Discontinuation Of Low-dose Levothyroxine Therapy For Patients With Subclinical Hypothyroidism Is Feasible: A Pilot, Randomized, Double-blind, Placebo-controlled Trial (2023)
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Feasibility of Reducing Animal Numbers in Radiation Countermeasure Experiments from Historic Levels when using Sample Size Calculations (2023)
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Determinants for Thyroid Hormone Replacement Therapy in Subclinical Hypothyroidism: A Multicenter Electronic Health Records-Based Study (2023)
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A peptide-based human papillomavirus therapeutic vaccine, PepCan, or <i>Candida</i> adjuvant alone in treatment of cervical intraepithelial neoplasia 2/3 (CIN2/3). (2023)
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The Revised PENIS Score and proposal of the PACKAGE Checklist: a meta-epidemiologic study on penile amputation and replantation (2023)
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TO STUDY THE OUTCOMES OF ATRIAL FIBRILLATION IN THE PATIENTS WITH MULTIPLE MYELOMA AFTER CHEMOTHERAPY AND AUTOLOGOUS STEM CELL TRANSPLANT AT THE MYELOMA CENTER, UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES (UAMS), LITTLE ROCK, AR (2023)
Collaboration Network
Top Collaborators
- sarA ‐mediated repression of protease production plays a key role in the pathogenesis of S taphylococcus aureus USA 300 isolates
- Impact of Extracellular Nuclease Production on the Biofilm Phenotype of Staphylococcus aureus under In Vitro and In Vivo Conditions
- Impact of individual extracellular proteases on Staphylococcus aureus biofilm formation in diverse clinical isolates and their isogenic sarA mutants
- Comparative impact of diverse regulatory loci on Staphylococcus aureus biofilm formation
- Evaluation of Antibiotics Active against Methicillin-Resistant Staphylococcus aureus Based on Activity in an Established Biofilm
Showing 5 of 15 shared publications
- sarA ‐mediated repression of protease production plays a key role in the pathogenesis of S taphylococcus aureus USA 300 isolates
- Impact of Extracellular Nuclease Production on the Biofilm Phenotype of Staphylococcus aureus under In Vitro and In Vivo Conditions
- Impact of individual extracellular proteases on Staphylococcus aureus biofilm formation in diverse clinical isolates and their isogenic sarA mutants
- Comparative impact of diverse regulatory loci on Staphylococcus aureus biofilm formation
- Evaluation of Antibiotics Active against Methicillin-Resistant Staphylococcus aureus Based on Activity in an Established Biofilm
Showing 5 of 15 shared publications
- Human papillomavirus type 16 viral load is decreased following a therapeutic vaccination
- A phase I dose-escalation clinical trial of a peptide-based human papillomavirus therapeutic vaccine with Candida skin test reagent as a novel vaccine adjuvant for treating women with biopsy-proven cervical intraepithelial neoplasia 2/3
- CD4+ T-cell response against human papillomavirus type 16 E6 protein is associated with a favorable clinical trend
- Candida skin test reagent as a novel adjuvant for a human papillomavirus peptide-based therapeutic vaccine
- Cervical Microbiome and Response to a Human Papillomavirus Therapeutic Vaccine for Treating High-Grade Cervical Squamous Intraepithelial Lesion
Showing 5 of 9 shared publications
- Trends in Robotic Thyroid Surgery in the United States from 2009 Through 2013
- Normocalcemic and Normohormonal Primary Hyperparathyroidism: Laboratory Values and End‐Organ Effects
- Implications of head and neck cancer treatment failure in the neck
- Hormone, Relationships of Parathyroid Gamma Counts, and Adenoma Mass in Minimally Invasive Parathyroidectomy
- Characteristics of Inpatient Thyroid Surgery at US Academic and Affiliated Medical Centers
Showing 5 of 8 shared publications
- Human papillomavirus type 16 viral load is decreased following a therapeutic vaccination
- A phase I dose-escalation clinical trial of a peptide-based human papillomavirus therapeutic vaccine with Candida skin test reagent as a novel vaccine adjuvant for treating women with biopsy-proven cervical intraepithelial neoplasia 2/3
- CD4+ T-cell response against human papillomavirus type 16 E6 protein is associated with a favorable clinical trend
- Candida skin test reagent as a novel adjuvant for a human papillomavirus peptide-based therapeutic vaccine
- Cervical Microbiome and Response to a Human Papillomavirus Therapeutic Vaccine for Treating High-Grade Cervical Squamous Intraepithelial Lesion
Showing 5 of 8 shared publications
- Human papillomavirus type 16 viral load is decreased following a therapeutic vaccination
- A phase I dose-escalation clinical trial of a peptide-based human papillomavirus therapeutic vaccine with Candida skin test reagent as a novel vaccine adjuvant for treating women with biopsy-proven cervical intraepithelial neoplasia 2/3
- Cervical polyps: Is histologic evaluation necessary?
- A Fibromyxoid Stromal Response Is Associated With an Infiltrative Tumor Morphology, Perineural Invasion, and Lymph Node Metastasis in Squamous Cell Carcinoma of the Vulva
- Pathologic features of aggressive vulvar carcinoma are associated with epithelial-mesenchymal transition
Showing 5 of 8 shared publications
- Determinants of discordance in patients' and physicians' rating of rheumatoid arthritis disease activity
- Patient's global assessment of disease activity and patient's assessment of general health for rheumatoid arthritis activity assessment: are they equivalent?
- Association of industry funding with the outcome and quality of randomized controlled trials of drug therapy for rheumatoid arthritis
- Randomized Controlled Trials of Rheumatoid Arthritis Registered at ClinicalTrials.gov: What Gets Published and When
- Association of author’s financial conflict of interest with characteristics and outcome of rheumatoid arthritis randomized controlled trials
Showing 5 of 7 shared publications
- Human papillomavirus type 16 viral load is decreased following a therapeutic vaccination
- A phase I dose-escalation clinical trial of a peptide-based human papillomavirus therapeutic vaccine with Candida skin test reagent as a novel vaccine adjuvant for treating women with biopsy-proven cervical intraepithelial neoplasia 2/3
- CD4+ T-cell response against human papillomavirus type 16 E6 protein is associated with a favorable clinical trend
- Cervical Microbiome and Response to a Human Papillomavirus Therapeutic Vaccine for Treating High-Grade Cervical Squamous Intraepithelial Lesion
- A novel use of a statewide telecolposcopy network for recruitment of participants in a Phase I clinical trial of a human papillomavirus therapeutic vaccine
Showing 5 of 7 shared publications
- Endoplasmic Reticulum Stress Markers Are Associated with Obesity in Nondiabetic Subjects
- Human Visfatin Expression: Relationship to Insulin Sensitivity, Intramyocellular Lipids, and Inflammation
- Retinol Binding Protein 4 Expression in Humans: Relationship to Insulin Resistance, Inflammation, and Response to Pioglitazone
- Thrombospondin-1 Is an Adipokine Associated With Obesity, Adipose Inflammation, and Insulin Resistance
- Lipin Expression Is Attenuated in Adipose Tissue of Insulin-Resistant Human Subjects and Increases With Peroxisome Proliferator–Activated Receptor γ Activation
Showing 5 of 7 shared publications
- Vitamin D Deficiency in Residents of Academic Long-Term Care Facilities Despite Having Been Prescribed Vitamin D
- Trends in Robotic Thyroid Surgery in the United States from 2009 Through 2013
- Hormone, Relationships of Parathyroid Gamma Counts, and Adenoma Mass in Minimally Invasive Parathyroidectomy
- Characteristics of Inpatient Thyroid Surgery at US Academic and Affiliated Medical Centers
- Conservative management of thyroglobulin‐positive, nonlocalizable thyroid carcinoma
Showing 5 of 6 shared publications
- sarA ‐mediated repression of protease production plays a key role in the pathogenesis of S taphylococcus aureus USA 300 isolates
- Chitosan coating to enhance the therapeutic efficacy of calcium sulfate-based antibiotic therapy in the treatment of chronic osteomyelitis
- Impact of the functional status of saeRS on in vivo phenotypes of S taphylococcus aureus sarA mutants
- Use of Xylitol To Enhance the Therapeutic Efficacy of Polymethylmethacrylate-Based Antibiotic Therapy in Treatment of Chronic Osteomyelitis
- BB0238, a Presumed Tetratricopeptide Repeat-Containing Protein, Is Required during Borrelia burgdorferi Mammalian Infection
Showing 5 of 6 shared publications
- Human papillomavirus type 16 viral load is decreased following a therapeutic vaccination
- A phase I dose-escalation clinical trial of a peptide-based human papillomavirus therapeutic vaccine with Candida skin test reagent as a novel vaccine adjuvant for treating women with biopsy-proven cervical intraepithelial neoplasia 2/3
- Plasma concentration of 3-hydroxyisovaleryl carnitine is an early and sensitive indicator of marginal biotin deficiency in humans
- Urinary Excretion of 3-Hydroxyisovaleric Acid and 3-Hydroxyisovaleryl Carnitine Increases in Response to a Leucine Challenge in Marginally Biotin-Deficient Humans
- Urinary Excretion of 3-Hydroxyisovaleryl Carnitine Is an Early and Sensitive Indicator of Marginal Biotin Deficiency in Humans,
Showing 5 of 6 shared publications
- Impact of individual extracellular proteases on Staphylococcus aureus biofilm formation in diverse clinical isolates and their isogenic sarA mutants
- Comparative impact of diverse regulatory loci on Staphylococcus aureus biofilm formation
- Impact of the functional status of saeRS on in vivo phenotypes of S taphylococcus aureus sarA mutants
- Impact of Staphylococcus aureus regulatory mutations that modulate biofilm formation in the USA300 strain LAC on virulence in a murine bacteremia model
- Regulatory Mutations Impacting Antibiotic Susceptibility in an Established Staphylococcus aureus Biofilm
Showing 5 of 6 shared publications
- Impact of individual extracellular proteases on Staphylococcus aureus biofilm formation in diverse clinical isolates and their isogenic sarA mutants
- Comparative impact of diverse regulatory loci on Staphylococcus aureus biofilm formation
- Evaluation of Antibiotics Active against Methicillin-Resistant Staphylococcus aureus Based on Activity in an Established Biofilm
- Impact of the functional status of saeRS on in vivo phenotypes of S taphylococcus aureus sarA mutants
- Impact of Staphylococcus aureus regulatory mutations that modulate biofilm formation in the USA300 strain LAC on virulence in a murine bacteremia model
Showing 5 of 6 shared publications
- Endoplasmic Reticulum Stress Markers Are Associated with Obesity in Nondiabetic Subjects
- Human Visfatin Expression: Relationship to Insulin Sensitivity, Intramyocellular Lipids, and Inflammation
- Retinol Binding Protein 4 Expression in Humans: Relationship to Insulin Resistance, Inflammation, and Response to Pioglitazone
- Thrombospondin-1 Is an Adipokine Associated With Obesity, Adipose Inflammation, and Insulin Resistance
- Lipin Expression Is Attenuated in Adipose Tissue of Insulin-Resistant Human Subjects and Increases With Peroxisome Proliferator–Activated Receptor γ Activation
Showing 5 of 6 shared publications
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