Charles Matthew Quick
Professor
Also affiliated: Cedars-Sinai Medical Center (2017); Brigham and Women's Hospital (2011–2017); Belfast Health and Social Care Trust (2017); Beth Israel Deaconess Medical Center (2017); Cleveland Clinic (2017); Memorial Sloan Kettering Cancer Center (2017); NewYork–Presbyterian Hospital (2017); The University of Texas MD Anderson Cancer Center (2017); Harvard University (2011–2017); University of California, San Francisco (2017); Baylor College of Medicine (2022); Vanderbilt University (2017–2020); University of Arkansas Medical Center (2012–2026); Emory University Hospital (2017); El Camino Hospital (2017); Baylor University Medical Center (2014); University of Alabama at Birmingham (2014); University of Saskatchewan (2018–2023); Yale University (2017); University of California San Diego (2017); Massachusetts General Hospital (2017); Central Arkansas Veterans Healthcare System (2006–2012); Hattiesburg Clinic (2023); Mills Peninsula Health Services (2017); Stanford Medicine (2017); Rocky Mountain Cancer Centers (2014); Radiology Associates of Albuquerque (2014); Johns Hopkins Hospital (2017); The US Oncology Network (2014); United States and Canadian Academy of Pathology (2020); The University of Texas Southwestern Medical Center (2019–2025); Vanderbilt University Medical Center (2017–2020); Stanford University (2017)
Pathology, College of Medicine
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Charles Matthew Quick's research focuses on the molecular and pathological aspects of gynecological cancers, particularly uterine and ovarian neoplasms. He has investigated the mutational landscape of these cancers, identifying key oncogenic mutations and their potential roles in disease progression, including epithelial-mesenchymal transition. His work has also explored specific subtypes of uterine and ovarian adenocarcinomas, such as mesonephric-like adenocarcinomas, and characterized their distinct molecular profiles, including recurrent KRAS mutations.
Quick's publications also address prognostic factors in endometrial carcinoma and the genomic underpinnings of uterine leiomyosarcomas. His research group at the University of Arkansas for Medical Sciences collaborates with other investigators at the institution and beyond, including Michael Cho, Yong-Chen Lu, Rosalia C. M. Simmen, and Narasimhan Rajaram. His work has been recognized with a high-impact researcher designation due to his citation count and publication record.
Metrics
- h-index: 35
- Publications: 178
- Citations: 3,973
Positions
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Professor & Vice Chair of Anatomic Pathology 2011–presentUniversity of Arkansas for Medical Sciences Pathology ORCID
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Professor publications 2006–2026University of Arkansas for Medical Sciences Pathology, College of Medicine Institutional directory
Selected Publications
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“Fibrosarcoma-like” Tumors of the Gynecologic Tract Show Distinct Molecular Subgroups: Tyrosine Kinase Fusions and Recurrent ERBB2/3 Mutations (2026)
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Hypertrophic Lichen Sclerosus (2026)
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“Dark Paget” Cells in Extramammary Paget Disease of the Vulva—Diagnostic Features and Interpretative Pitfalls (2026)
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Abstract 2908: SR-A antagonism remodels the myeloid population of tumor immune microenvironment, expands CD8-positive T cells, and enhances antitumor efficacy in vivo (2026)
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Polypoid endometriosis with endometrioid intraepithelial neoplasia mimicking malignancy: a rare case of a postmenopausal pelvic mass (2026)
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986 “Fibrosarcoma-like” Tumors of the Gynecologic Tract Show Overlapping Morphology but Distinct Molecular Subgroups Including Those with Gene Fusions and Recurrent ERBB2/3 Mutations (2026)
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993 Interobserver Agreement and Diagnostic Certainty in Adenosarcoma (2026)
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430 Democratizing Continuing Medical Education (CME) Globally by Free, Interactive, Virtual Programming from the International Society of Gynecological Pathologists (ISGyP): Sustainable Engagement by Low-Middle Income Country (LMIC) Pathologists and Trainees between 2021 and 2025 (2026)
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958 Hypertrophic Lichen Sclerosus: A Form of “Atypical” Lichen Sclerosus in the Pathway to HPV-Independent Squamous Cell Carcinoma of the Vulva (2026)
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383 “Dark Paget” Cells in Extramammary Paget Disease of the Vulva – Diagnostic Features and Interpretative Pitfalls (2026)
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931 Leveraging Cloud-Based Whole Slide Imaging for Rare Cancer Repository Building: Uterine Mesenchymal Tumors (2026)
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Detection of mitochondrial DNA mutations in T cells following 5-FU or cisplatin exposure (2026)
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Isolation of mitochondrial mutation-specific T cell receptors (2025)
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Endometrial Carcinogenesis (2025)
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Principles and Practical Guidelines of Intraoperative Consultation (2025)
Collaboration Network
Top Collaborators
- Frequent Expression of Napsin A in Clear Cell Carcinoma of the Endometrium
- Targeted Molecular and Immunohistochemical Analyses of Endometrial Clear Cell Carcinoma Show that POLE Mutations and DNA Mismatch Repair Protein Deficiencies Are Uncommon
- Utility of α-methylacyl-coenzyme-A racemase (p504s) immunohistochemistry in distinguishing endometrial clear cell carcinomas from serous and endometrioid carcinomas
- Clear Cell Renal Cell Carcinoma Metastatic to the Gynecologic Tract: A Clinicopathologic Analysis of 17 Cases
- Are clear cell carcinomas of the ovary and endometrium phenotypically identical? A proteomic analysis
Showing 5 of 24 shared publications
- Frequent Expression of Napsin A in Clear Cell Carcinoma of the Endometrium
- Comparative analysis of Napsin A, alpha-methylacyl-coenzyme A racemase (AMACR, P504S), and hepatocyte nuclear factor 1 beta as diagnostic markers of ovarian clear cell carcinoma: an immunohistochemical study of 279 ovarian tumours
- Targeted Molecular and Immunohistochemical Analyses of Endometrial Clear Cell Carcinoma Show that POLE Mutations and DNA Mismatch Repair Protein Deficiencies Are Uncommon
- Utility of α-methylacyl-coenzyme-A racemase (p504s) immunohistochemistry in distinguishing endometrial clear cell carcinomas from serous and endometrioid carcinomas
- Clear Cell Renal Cell Carcinoma Metastatic to the Gynecologic Tract: A Clinicopathologic Analysis of 17 Cases
Showing 5 of 23 shared publications
- Interobserver Variability in the Application of a Proposed Histologic Subclassification of Endocervical Adenocarcinoma
- A phase I dose-escalation clinical trial of a peptide-based human papillomavirus therapeutic vaccine with Candida skin test reagent as a novel vaccine adjuvant for treating women with biopsy-proven cervical intraepithelial neoplasia 2/3
- Pax2 Expression in Simultaneously Diagnosed WHO and EIN Classification Systems
- Accentuated p53 staining in usual type vulvar dysplasia—A potential diagnostic pitfall
- A novel use of a statewide telecolposcopy network for recruitment of participants in a Phase I clinical trial of a human papillomavirus therapeutic vaccine
Showing 5 of 16 shared publications
- Human papillomavirus type 16 viral load is decreased following a therapeutic vaccination
- A phase I dose-escalation clinical trial of a peptide-based human papillomavirus therapeutic vaccine with Candida skin test reagent as a novel vaccine adjuvant for treating women with biopsy-proven cervical intraepithelial neoplasia 2/3
- Cervical polyps: Is histologic evaluation necessary?
- Pathologic features of aggressive vulvar carcinoma are associated with epithelial-mesenchymal transition
- Expansion of Human Papillomavirus-Specific T Cells in Periphery and Cervix in a Therapeutic Vaccine Recipient Whose Cervical High-Grade Squamous Intraepithelial Lesion Regressed
Showing 5 of 9 shared publications
- Enhanced Gastrointestinal Expression of Cytosolic Malic Enzyme (ME1) Induces Intestinal and Liver Lipogenic Gene Expression and Intestinal Cell Proliferation in Mice
- Notch-1 Signaling Activation and Progesterone Receptor Expression in Ectopic Lesions of Women With Endometriosis
- Metformin Promotes Anti-tumor Biomarkers in Human Endometrial Cancer Cells
- Co-morbidity of type 1 diabetes and endometriosis: bringing a new paradigm into focus
- A Pilot Study on the Co-existence of Diabetes and Endometriosis in Reproductive-Age Women: Potential for Endometriosis Progression
Showing 5 of 9 shared publications
- Label-Free Raman Spectroscopy Reveals Signatures of Radiation Resistance in the Tumor Microenvironment
- Longitudinal monitoring of tumor response to immune checkpoint inhibitors using noninvasive diffuse reflectance spectroscopy
- Investigating the relationship between hypoxia, hypoxia-inducible factor 1, and the optical redox ratio in response to radiation therapy
- Data from Raman Spectroscopy and Machine Learning Reveals Early Tumor Microenvironmental Changes Induced by Immunotherapy
- Supplementary Data from Raman Spectroscopy and Machine Learning Reveals Early Tumor Microenvironmental Changes Induced by Immunotherapy
Showing 5 of 9 shared publications
- Human papillomavirus type 16 viral load is decreased following a therapeutic vaccination
- A phase I dose-escalation clinical trial of a peptide-based human papillomavirus therapeutic vaccine with Candida skin test reagent as a novel vaccine adjuvant for treating women with biopsy-proven cervical intraepithelial neoplasia 2/3
- Expansion of Human Papillomavirus-Specific T Cells in Periphery and Cervix in a Therapeutic Vaccine Recipient Whose Cervical High-Grade Squamous Intraepithelial Lesion Regressed
- A novel use of a statewide telecolposcopy network for recruitment of participants in a Phase I clinical trial of a human papillomavirus therapeutic vaccine
- A Randomized Double-Blind Phase 2 Clinical Trial Treating Cervical Intraepithelial Neoplasia 2/3 with PepCan or Candida
Showing 5 of 8 shared publications
- Frequent Expression of Napsin A in Clear Cell Carcinoma of the Endometrium
- Comparative analysis of Napsin A, alpha-methylacyl-coenzyme A racemase (AMACR, P504S), and hepatocyte nuclear factor 1 beta as diagnostic markers of ovarian clear cell carcinoma: an immunohistochemical study of 279 ovarian tumours
- Targeted Molecular and Immunohistochemical Analyses of Endometrial Clear Cell Carcinoma Show that POLE Mutations and DNA Mismatch Repair Protein Deficiencies Are Uncommon
- Utility of α-methylacyl-coenzyme-A racemase (p504s) immunohistochemistry in distinguishing endometrial clear cell carcinomas from serous and endometrioid carcinomas
- Clear Cell Renal Cell Carcinoma Metastatic to the Gynecologic Tract: A Clinicopathologic Analysis of 17 Cases
Showing 5 of 8 shared publications
- Human papillomavirus type 16 viral load is decreased following a therapeutic vaccination
- A phase I dose-escalation clinical trial of a peptide-based human papillomavirus therapeutic vaccine with Candida skin test reagent as a novel vaccine adjuvant for treating women with biopsy-proven cervical intraepithelial neoplasia 2/3
- Expansion of Human Papillomavirus-Specific T Cells in Periphery and Cervix in a Therapeutic Vaccine Recipient Whose Cervical High-Grade Squamous Intraepithelial Lesion Regressed
- A Randomized Double-Blind Phase 2 Clinical Trial Treating Cervical Intraepithelial Neoplasia 2/3 with PepCan or Candida
- A peptide-based human papillomavirus therapeutic vaccine, PepCan, or Candida adjuvant alone in treatment of cervical intraepithelial neoplasia 2/3 (CIN2/3).
Showing 5 of 7 shared publications
- Frequent Expression of Napsin A in Clear Cell Carcinoma of the Endometrium
- Comparative analysis of Napsin A, alpha-methylacyl-coenzyme A racemase (AMACR, P504S), and hepatocyte nuclear factor 1 beta as diagnostic markers of ovarian clear cell carcinoma: an immunohistochemical study of 279 ovarian tumours
- Utility of α-methylacyl-coenzyme-A racemase (p504s) immunohistochemistry in distinguishing endometrial clear cell carcinomas from serous and endometrioid carcinomas
- Clear Cell Renal Cell Carcinoma Metastatic to the Gynecologic Tract: A Clinicopathologic Analysis of 17 Cases
- Are clear cell carcinomas of the ovary and endometrium phenotypically identical? A proteomic analysis
Showing 5 of 7 shared publications
- Frequent Expression of Napsin A in Clear Cell Carcinoma of the Endometrium
- Targeted Molecular and Immunohistochemical Analyses of Endometrial Clear Cell Carcinoma Show that POLE Mutations and DNA Mismatch Repair Protein Deficiencies Are Uncommon
- Utility of α-methylacyl-coenzyme-A racemase (p504s) immunohistochemistry in distinguishing endometrial clear cell carcinomas from serous and endometrioid carcinomas
- Clear Cell Renal Cell Carcinoma Metastatic to the Gynecologic Tract: A Clinicopathologic Analysis of 17 Cases
- Are clear cell carcinomas of the ovary and endometrium phenotypically identical? A proteomic analysis
Showing 5 of 7 shared publications
- Hepatotoxicity of a Cannabidiol-Rich Cannabis Extract in the Mouse Model
- Paradoxical Patterns of Sinusoidal Obstruction Syndrome-Like Liver Injury in Aged Female CD-1 Mice Triggered by Cannabidiol-Rich Cannabis Extract and Acetaminophen Co-Administration
- Modulation of dietary methionine intake elicits potent, yet distinct, anticancer effects on primary versus metastatic tumors
- Potential Probiotic or Trigger of Gut Inflammation – The Janus-Faced Nature of Cannabidiol-Rich Cannabis Extract
- Safety and Molecular-Toxicological Implications of Cannabidiol-Rich Cannabis Extract and Methylsulfonylmethane Co-Administration
Showing 5 of 7 shared publications
- Hepatotoxicity of a Cannabidiol-Rich Cannabis Extract in the Mouse Model
- Paradoxical Patterns of Sinusoidal Obstruction Syndrome-Like Liver Injury in Aged Female CD-1 Mice Triggered by Cannabidiol-Rich Cannabis Extract and Acetaminophen Co-Administration
- Modulation of dietary methionine intake elicits potent, yet distinct, anticancer effects on primary versus metastatic tumors
- Potential Probiotic or Trigger of Gut Inflammation – The Janus-Faced Nature of Cannabidiol-Rich Cannabis Extract
- Safety and Molecular-Toxicological Implications of Cannabidiol-Rich Cannabis Extract and Methylsulfonylmethane Co-Administration
Showing 5 of 7 shared publications
- Label-Free Raman Spectroscopy Reveals Signatures of Radiation Resistance in the Tumor Microenvironment
- Longitudinal monitoring of tumor response to immune checkpoint inhibitors using noninvasive diffuse reflectance spectroscopy
- Data from Raman Spectroscopy and Machine Learning Reveals Early Tumor Microenvironmental Changes Induced by Immunotherapy
- Supplementary Data from Raman Spectroscopy and Machine Learning Reveals Early Tumor Microenvironmental Changes Induced by Immunotherapy
- Data from Raman Spectroscopy and Machine Learning Reveals Early Tumor Microenvironmental Changes Induced by Immunotherapy
Showing 5 of 7 shared publications
- Investigating the relationship between hypoxia, hypoxia-inducible factor 1, and the optical redox ratio in response to radiation therapy
- Data from Raman Spectroscopy and Machine Learning Reveals Early Tumor Microenvironmental Changes Induced by Immunotherapy
- Supplementary Data from Raman Spectroscopy and Machine Learning Reveals Early Tumor Microenvironmental Changes Induced by Immunotherapy
- Data from Raman Spectroscopy and Machine Learning Reveals Early Tumor Microenvironmental Changes Induced by Immunotherapy
- Supplementary Data from Raman Spectroscopy and Machine Learning Reveals Early Tumor Microenvironmental Changes Induced by Immunotherapy
Showing 5 of 7 shared publications
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