J
James Losey Data-verified
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Postdoctoral Fellow
postdoc
7 h-index
19 pubs
122 cited
Research Areas
Links
Biography and Research Information
OverviewAI-generated summary
James Losey's research focuses on computational studies of protein dynamics, particularly in the context of viral infections and protein engineering. He investigates the conformational changes of viral spike proteins, such as those found in SARS-CoV-2, using molecular dynamics simulations and fluorescence resonance energy transfer (FRET) techniques. His work also extends to developing computational approaches for designing recombinant proteins and understanding the embeddability problem in transition rate estimation. Losey has published on topics including secondary structure in intrinsically disordered protein regions and the computational elucidation of fusion protein effects on nanoparticle synthesis. He has a collaborative network within the University of Arkansas at Fayetteville, with multiple shared publications with researchers including Mahmoud Moradi and Vivek Govind Kumar. His work has resulted in 19 publications and 122 citations, with an h-index of 7.
Metrics
- h-index: 7
- Publications: 19
- Citations: 122
Selected Publications
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Simulating Freely Diffusing Single-Molecule FRET Data with Consideration of Protein Conformational Dynamics (2026)
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BPS2025 - Along-the-path Markov models for state transition in a major facilitator superfamily transporter (2025)
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Transition rate estimation from along-the-path, unbiased, molecular dynamics simulations of a major facilitator superfamily transporter (2024)
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Addressing the Embeddability Problem in Transition Rate Estimation (2023)
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Developing a rational approach to designing recombinant proteins for peptide-directed nanoparticle synthesis (2022)
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Simulating freely-diffusing single-molecule FRET data with consideration of protein conformational dynamics (2022)
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Prefusion spike protein conformational changes are slower in SARS-CoV-2 than in SARS-CoV-1 (2022)
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Addressing the embeddability problem in transition rate estimation from Markov state models (2022)
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Transient local secondary structure in the intrinsically disordered C-term of the Albino3 insertase (2021)
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Computational Elucidation of Recombinant Fusion Protein Effect on Peptide-Directed Nanoparticles (2021)
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Integrating Molecular Dynamics and smFRET Data to Study the Conformational Ensemble of the C-Terminus of Albino3 Protein (2021)
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Differential Dynamic Behavior of Prefusion Spike Glycoproteins of Sars Coronaviruses 1 and 2 (2021)
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Simulating freely-diffusing single-molecule FRET data with consideration of protein conformational dynamics (2021)
Collaboration Network
Top Collaborators
Mahmoud Moradi
University of Arkansas at Fayetteville
13 shared publications
In database
- Prefusion spike protein conformational changes are slower in SARS-CoV-2 than in SARS-CoV-1
- Developing a rational approach to designing recombinant proteins for peptide-directed nanoparticle synthesis
- Transient local secondary structure in the intrinsically disordered C-term of the Albino3 insertase
- Addressing the Embeddability Problem in Transition Rate Estimation
- Computational Elucidation of Recombinant Fusion Protein Effect on Peptide-Directed Nanoparticles
Showing 5 of 13 shared publications
David S. Matteson
Cornell University (US)
4 shared publications
- Addressing the Embeddability Problem in Transition Rate Estimation
- Simulating freely-diffusing single-molecule FRET data with consideration of protein conformational dynamics
- Simulating freely-diffusing single-molecule FRET data with consideration of protein conformational dynamics
- Addressing the embeddability problem in transition rate estimation from Markov state models
Vivek Govind Kumar
University of Arkansas at Fayetteville
4 shared publications
In database
- Prefusion spike protein conformational changes are slower in SARS-CoV-2 than in SARS-CoV-1
- Transient local secondary structure in the intrinsically disordered C-term of the Albino3 insertase
- Differential Dynamic Behavior of Prefusion Spike Glycoproteins of Sars Coronaviruses 1 and 2
- Integrating Molecular Dynamics and smFRET Data to Study the Conformational Ensemble of the C-Terminus of Albino3 Protein
Adithya Polasa
University of Arkansas at Fayetteville
4 shared publications
In database
- Prefusion spike protein conformational changes are slower in SARS-CoV-2 than in SARS-CoV-1
- Developing a rational approach to designing recombinant proteins for peptide-directed nanoparticle synthesis
- Computational Elucidation of Recombinant Fusion Protein Effect on Peptide-Directed Nanoparticles
- Simulating Freely Diffusing Single-Molecule FRET Data with Consideration of Protein Conformational Dynamics
Curtis Goolsby
University of Arkansas at Fayetteville
4 shared publications
In database
- Addressing the Embeddability Problem in Transition Rate Estimation
- Addressing the embeddability problem in transition rate estimation from Markov state models
- Transition rate estimation from along-the-path, unbiased, molecular dynamics simulations of a major facilitator superfamily transporter
- BPS2025 - Along-the-path Markov models for state transition in a major facilitator superfamily transporter
Michael Jauch
Florida State University (US)
3 shared publications
- Simulating freely-diffusing single-molecule FRET data with consideration of protein conformational dynamics
- Simulating freely-diffusing single-molecule FRET data with consideration of protein conformational dynamics
- Simulating Freely Diffusing Single-Molecule FRET Data with Consideration of Protein Conformational Dynamics
Axel Cortés‐Cubero
University of Puerto Rico System (PR)
3 shared publications
- Simulating freely-diffusing single-molecule FRET data with consideration of protein conformational dynamics
- Simulating freely-diffusing single-molecule FRET data with consideration of protein conformational dynamics
- Simulating Freely Diffusing Single-Molecule FRET Data with Consideration of Protein Conformational Dynamics
Haoxuan Wu
Cornell University (US)
3 shared publications
- Simulating freely-diffusing single-molecule FRET data with consideration of protein conformational dynamics
- Simulating freely-diffusing single-molecule FRET data with consideration of protein conformational dynamics
- Simulating Freely Diffusing Single-Molecule FRET Data with Consideration of Protein Conformational Dynamics
Roberto Rivera
University of Puerto Rico-Mayaguez (PR)
2 shared publications
- Simulating freely-diffusing single-molecule FRET data with consideration of protein conformational dynamics
- Simulating freely-diffusing single-molecule FRET data with consideration of protein conformational dynamics
Dylan S. Ogden
University of Arkansas at Fayetteville
2 shared publications
In database
- Prefusion spike protein conformational changes are slower in SARS-CoV-2 than in SARS-CoV-1
- Differential Dynamic Behavior of Prefusion Spike Glycoproteins of Sars Coronaviruses 1 and 2
Ugochi H. Isu
University of Arkansas at Fayetteville
2 shared publications
In database
- Prefusion spike protein conformational changes are slower in SARS-CoV-2 than in SARS-CoV-1
- Differential Dynamic Behavior of Prefusion Spike Glycoproteins of Sars Coronaviruses 1 and 2
Dustin Baucom
University of Arkansas at Fayetteville
2 shared publications
In database
- Transient local secondary structure in the intrinsically disordered C-term of the Albino3 insertase
- Integrating Molecular Dynamics and smFRET Data to Study the Conformational Ensemble of the C-Terminus of Albino3 Protein
Mercede Furr
University of Arkansas at Fayetteville
2 shared publications
In database
- Transient local secondary structure in the intrinsically disordered C-term of the Albino3 insertase
- Integrating Molecular Dynamics and smFRET Data to Study the Conformational Ensemble of the C-Terminus of Albino3 Protein
Colin D. Heyes
University of Arkansas at Fayetteville
2 shared publications
In database
- Transient local secondary structure in the intrinsically disordered C-term of the Albino3 insertase
- Integrating Molecular Dynamics and smFRET Data to Study the Conformational Ensemble of the C-Terminus of Albino3 Protein
Imann Mosleh
Cornell University (US)
2 shared publications
- Developing a rational approach to designing recombinant proteins for peptide-directed nanoparticle synthesis
- Computational Elucidation of Recombinant Fusion Protein Effect on Peptide-Directed Nanoparticles
Similar Researchers
Based on overlapping research topics
Parth Chaturvedi
University of Arkansas at Fayetteville
SARS-CoV-2 and COVID-19 Research
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Vivek Govind Kumar
University of Arkansas at Fayetteville
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Dylan S. Ogden
University of Arkansas at Fayetteville
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Ibraheem Abbood
University of Arkansas at Little Rock
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Mitu C. Acharjee
University of Arkansas at Fayetteville
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Kaynat Shahzad
University of Arkansas at Fayetteville
Protein Structure and Dynamics
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