Ikjae Shin

Instructor

UAMS

Also affiliated: The University of Texas MD Anderson Cancer Center (2016); University of Arkansas Medical Center (2020–2021)

Internal Med, College of Medicine

1 h-index 8 pubs 9 cited

Research Areas

Biomedical Subjects

Links

Research Group UAMS TRI Profile

OverviewAI-generated summary

Ikjae Shin's research investigates molecular mechanisms underlying disease, with a focus on cellular signaling pathways and their roles in conditions such as cancer and atherosclerosis. His work has involved studying the phosphorylation of signaling molecules like ERK and CREB in response to various stimuli, including statins and lipopolysaccharides, and their impact on gene expression, such as MMP-9. Shin has also explored the interplay between endothelial activation, endoplasmic reticulum stress, and the development of atherosclerosis, utilizing mouse models and molecular imaging techniques. Additionally, his publications include research on lung cancer, examining the potential of liquid biopsies and analyzing complex human tumors through genomics and radiomics. He collaborates with researchers at the University of Arkansas for Medical Sciences, including Donald J. Johann, Matthew A. Steliga, Jason Muesse, and Eric C. Peterson.

Metrics

h-index: 1
Publications: 8
Citations: 9

Positions

Instructor publications 2016–2024

University of Arkansas for Medical Sciences Internal Med, College of Medicine Institutional directory

Selected Publications

A Microdissection Protocol for Proteogenomic Analysis of Histological Sections to Advance Drug Development (2024)

Methods in molecular biology DOI OpenAlex
Advancing drug development by leveraging microdissection for proteogenomic analysis of histological sections. (2024)

Journal of Clinical Oncology DOI OpenAlex
Liquid biopsy based on circulating tumor DNA for lung cancer: A step toward prevention (2023)

Elsevier eBooks DOI OpenAlex
An advanced molecular medicine case report of a rare human tumor using genomics, pathomics, and radiomics (2023)

Frontiers in Genetics 6 citations DOI OpenAlex
Effect of Antigen Retrieval on Genomic DNA From Immunodissected Samples (2022)

Journal of Histochemistry & Cytochemistry 4 citations DOI OpenAlex
Abstract 5038: Applying reproducible genomic data science methods for the analysis of a rare tumor type (2022)

Cancer Research 1 citation DOI OpenAlex
Microdissection Methods Utilizing Single-Cell Subtype Analysis and the Impact on Precision Medicine (2022)

Methods in molecular biology 2 citations DOI OpenAlex
NPARS—A Novel Approach to Address Accuracy and Reproducibility in Genomic Data Science (2021)

Frontiers in Big Data 4 citations DOI OpenAlex
Synergizing microdissection with ddPCR to advance precision oncology. (2021)

Journal of Clinical Oncology 1 citation DOI OpenAlex
Utilizing single-cell-subtype analysis via advanced microdissection methods and the impact on precision medicine. (2020)

Journal of Clinical Oncology DOI OpenAlex
Visualizing collagen proteolysis by peptide hybridization: From 3D cell culture to in vivo imaging (2018)

Biomaterials 86 citations DOI OpenAlex
Liquid biopsy and its role in an advanced clinical trial for lung cancer (2018)

Experimental Biology and Medicine 51 citations DOI OpenAlex
Thymic PTH Increases After Thyroparathyroidectomy in C57BL/KaLwRij Mice (2018)

Endocrinology 6 citations DOI OpenAlex
Surgical thyroparathyroidectomy prevents progression of 5TGM1 murine multiple myeloma in vivo (2018)

Journal of bone oncology 4 citations DOI OpenAlex
Rigosertib, a Pan RAS Inhibitor, Decreases Mouse and Human Myeloma Cell Growth in Preclinical Models (2016)

Blood 1 citation DOI OpenAlex

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Grants & Funding

As listed on this researcher's institutional profile.

Scientific and methodological advancement in liquid biopsies to further the development of lung cancer-based precision medicine (Bio 3) U.S. Food and Drug Administration via Arkansas Research Alliance Co-Investigator