Jien Li Source Confirmed

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

Researcher

John Brown University

faculty

6 h-index 9 pubs 294 cited

Research Areas

Epigenetics and DNA Methylation Genomics and Phylogenetic Studies Genetics, Aging, and Longevity in Model Organisms RNA and protein synthesis mechanisms Bacterial Genetics and Biotechnology

Links

ORCID

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OverviewAI-generated summary

Jien Li's research encompasses diverse areas of genetics and biotechnology, including bacterial genetics, RNA and protein synthesis, and the roles of epigenetics and DNA methylation. Li has contributed to understanding how bacterial pan-genomes influence gene essentiality and evolvability. Recent work also explores the potential of chemical reprogramming to reverse cellular aging, as well as the impact of long-term NMN treatment on lifespan and healthspan in mice, with observed sex-dependent effects. Li's investigations into DNA methylation have led to the development of TIME-seq, a method for reducing the time and cost of DNA methylation measurement to construct epigenetic clocks.

Li's primary research interests involve aging and longevity in model organisms, alongside genomics and phylogenetic studies.

Metrics

  • h-index: 6
  • Publications: 9
  • Citations: 294

Selected Publications

  • From Circles to Signals: Representation Learning on Ultra-Long Extrachromosomal Circular DNA (2025) DOI

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