Jim Zhongning Chen

Sourced from institutional research profiles (UAMS TRI or ARA).

Researcher

UAMS primary UA Little Rock

Also affiliated: Clinical Insights (2025)

Faculty Researcher

2 h-index 19 pubs 58 cited

Research Areas

Biomedical Subjects

Links

ORCID Research Group UAMS TRI Profile

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OverviewAI-generated summary

Jim Zhongning Chen's research interests encompass a range of medical and biological topics, as indicated by his recent publications. He has investigated the clinical implications of stem cell theory in cancer, focusing on cellular metabolism and anti-cancer metabolomics, as well as the role of epigenomic versus genomic biomarkers. Chen has also explored predictive factors for adjuvant therapy in colon cancer, examining proliferation-related genes. His work includes analyzing real-world outcomes of neoadjuvant HER2-directed therapy in breast cancer using AI-enhanced data pipelines and evaluating bispecific antibodies in community oncology settings.

Further areas of his research include identifying microRNA biomarkers for refractory germ cell tumors and assessing cutaneous involvement by peripheral T-cell lymphoma. Chen has also contributed to studies on cardiovascular function, specifically comparing echocardiographic and catheter-based measurements of the Fontan fenestration gradient. His collaborations include shared publications with Alan Baltz, Timothy Langford, and Neriman Gökden at the University of Arkansas for Medical Sciences.

Metrics

h-index: 2
Publications: 19
Citations: 58

Selected Publications

Role of proliferation-related genes as predictive factors for adjuvant therapy in colon cancer. (2025)

Journal of Clinical Oncology DOI OpenAlex
Cutaneous Involvement By Peripheral T-Cell Lymphoma: Incidence, Characteristics, Treatment Trends, and Outcomes in the United States (2000-2021) (2024)

Blood DOI OpenAlex
Comparison of Echocardiographically-Calculated Fontan Fenestration Gradient and Catheter-Based Measurement (2024)

Pediatric Cardiology 1 citation DOI OpenAlex
Comparison of Echocardiographically-Calculated Fontan Fenestration Gradient and Catheter-Based Measurement (2024)

Research Square DOI OpenAlex
Abstract 1567: Honing in on the metastasis machinery (2024)

Cancer Research DOI OpenAlex
Stem Cell Theory of Cancer: Clinical Implications for Cellular Metabolism and Anti-Cancer Metabolomics (2024)

Cancers 4 citations DOI OpenAlex
Identification of a panel of microRNA biomarkers for the management of patients with refractory germ cell tumor of the testis. (2024)

Journal of Clinical Oncology 1 citation DOI OpenAlex
Interdigitating Dendritic Cell Sarcoma and Indeterminate Dendritic Cell Tumor: Patient Characteristics, Prognostic Factors, and Survival Outcomes for Rare Dendritic Cell Neoplasms (2023)

Blood DOI OpenAlex
Stem Cell Theory of Cancer: Clinical Implications of Epigenomic versus Genomic Biomarkers in Cancer Care (2023)

Cancers 1 citation DOI OpenAlex
Participation in a multidisciplinary institutional committee, “RQUEST,” to enhance quality improvement education, project design, and implementation for hematology/oncology fellows. (2023)

Journal of Clinical Oncology DOI OpenAlex
Weight loss (WL) as a predictive factor for immune oncology (IO). (2023)

Journal of Clinical Oncology DOI OpenAlex
Bilateral germ cell tumor of the testis (TGCT): Implications for a stem cell versus genetic origin of cancers. (2023)

Journal of Clinical Oncology DOI OpenAlex
Origin of extragonadal versus gonadal seminomas. (2023)

Journal of Clinical Oncology DOI OpenAlex
Validity of mutations as a cancer chronometer. (2022)

Journal of Clinical Oncology DOI OpenAlex
Biomarkers of inflammation, hypercoagulability and endothelial injury predict early asymptomatic doxorubicin-induced cardiotoxicity in breast cancer patients. (2020)

PubMed 49 citations OpenAlex