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Current · Arkansas
Last published
2026
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OpenAlex · ORCID
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2026-10-08
P
Ping-Ching Hsu
Federal Grant PI
Associate Professor
Also affiliated: National Defense University (2004); Tri-Service General Hospital (2003–2005); Chang Gung University (2002); Georgetown University (2010); University of Arkansas Medical Center (2024); The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (2012–2016); Taipei Medical University Hospital (2002); The Ohio State University Wexner Medical Center (2013); National Defense University (2003); Taipei Medical University (2001–2002); The Ohio State University (2015–2016); National Defense Medical Center (2003–2005); The University of Texas Southwestern Medical Center (2022)
Environmental Health Sciences, College of Public Health
14 h-index
96 pubs
806 cited
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Ping-Ching Hsu's research focuses on the application of metabolomics and mass spectrometry techniques to investigate health outcomes, particularly in relation to environmental exposures and disease. Her work has explored the feasibility of identifying tobacco-related metabolites in blood and has examined the metabolomic profiles of cigarette smokers. Hsu has also investigated biomarkers associated with cardiotoxicity in breast cancer patients and the link between pesticide exposure and colorectal cancer risk.
Hsu has received federal funding from the NIH/National Institute of Environmental Health Sciences for two grants totaling over $778,000. Both grants, the Arkansas Rural Community Health-Healthy Environmental Research (ARCH-HER) Study and Promoting scientific and workforce diversity by enriching the Arkansas Rural Community Health Study (ARCH) among Mother-Daughter Pairs, are PI-led and focus on environmental health research within rural Arkansas communities, including studies involving mother-daughter pairs.
Her recent publications demonstrate a commitment to quality assurance and control in untargeted metabolomics studies, including systematic reviews and scoping reviews on best practices. Hsu collaborates with several researchers at the University of Arkansas for Medical Sciences, including Renny S. Lan and Shelbie Stahr, with whom she shares numerous publications. With 96 total publications and an h-index of 14, her work contributes to the fields of environmental health, public health, and metabolomics.
Metrics
- h-index: 14
- Publications: 96
- Citations: 806
Positions
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Associate Professor 2016–presentUniversity of Arkansas for Medical Sciences Environmental Health Sciences, College of Public Health Institutional directory
Selected Publications
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Sézary Syndrome Biomarker, T Cell Transcription Factors and Cytokine Genes Provide Novel Insight into Response During Mogamulizumab Treatment (2026)
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Metabolic phenotypes of doxorubicin-induced cardiotoxicity among patients with breast cancer (2026)
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Abstract LB219: Proteomic signatures of doxorubicin-induced lymphatic dysfunction in tumor-bearing rats (2026)
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Abstract 7649: Urinary arsenic speciation and metabolic indices associate with exposure chemistry and prostate cancer aggressiveness. (2026)
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Additional file 2 of Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study (2026)
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Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study (2026)
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Additional file 2 of Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study (2026)
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Additional file 1 of Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study (2026)
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Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study (2026)
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Additional file 1 of Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study (2026)
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Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study (2026)
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Modified tumor uptake and biodistribution of nanoparticles coated with small extracellular vesicle membranes derived from distinct tumor cell lines (2026)
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DNA Methylation in Lung Cancer: Predictive Biomarkers for Effective Immunotherapy (2025)
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Abstract A058: Plasma folate and folic acid status in relation to prostate cancer aggressiveness: Insights into racial disparities from the PCaP study (2025)
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Abstract A064: Racial disparities in folate metabolism, genetic variants, and prostate cancer aggressiveness (2025)
Federal Grants 2 $778,801 total
NIH
Contact PI
Dec 2024 - Nov 2029
Arkansas Rural Community Health-Healthy Environmental Research (ARCH-HER) Study
NIH
Contact PI
Dec 2024 - Nov 2029
Research Interests
My laboratory is interested in biomarker discovery using global metabolite profiling (metabolomics). We use metabolomics to identify the “metabotype” that are consisting of oxidized lipids and metabolites in patients and animal models hoping to find early indicators of chemotherapy-induced cardiotoxicity and cognitive impairments in breast cancer patients. We also work on addressing the issue of cigarette smoking especially menthol cigarette smoking that’s contributing to the disparity of lethal prostate cancer in African-Americans, by identifying smoking-related metabolomics patterns associated with highly aggressive prostate cancer in African-Americans compared to European-Americans.
Grants & Funding
As listed on this researcher's institutional profile. Federal awards with verified records are shown above.
- Feasibility study to improve the assessment of cancer treatment-related cognitive impairment. Winthrop P. Rockefeller Team Science Pilot Award Principal Investigator
- Long-term effects of electronic cigarettes on brain health NIH/Nat. Inst. on Drug Abuse via Wake Forest University Principal Investigator
- Metabolomics of Menthol Cigarette Smoking and Risk for Aggressive Prostate Cancer Among African American Men US Department of Defense Principal Investigator
- Modulation effect of folate on the association between inorganic arsenic and aggressive prostate cancer US Department of Defense via University of Texas Southwestern Medical Center Principal Investigator
- Center for Studies of Host Response to Cancer Therapy NIH Principal Investigator
- Component A: Arkansas Proposal to participate in the Birth Defect Study to Evaluate Pregnancy exposureS (BD-STEPS II) Center for Disease Control and Prevention Co-Investigator
- Evaluating Impact of Diet and Fresh Food Access on Aggressive Prostate Cancer using Multi-Level Modeling NIH/Nat. Cancer Institute Principal Investigator
- Interaction of lug microbiome and tobaccorelated insults in lung cancer UAMS Internal Research Awards Principal Investigator
- Cancer Prevention and Population Sciences Program UAMS College of Medicine Principal Investigator
- RFA-DD-18-001 Birth Defects Study To Evaluate Pregnancy exposures (BD-STEPS) II Core & Component B Steps -Stillbirth NIH Co-Investigator
- Metabolomics of menthol cigarette smoking and risk for aggressive prostate cancer among African-American men US Department of Defense Principal Investigator
Collaboration Network
Top Collaborators
Lora J. Rogers
University of Arkansas for Medical Sciences
18 shared publications
In database
- Genome-wide DNA methylation signatures to predict pathologic complete response from combined neoadjuvant chemotherapy with bevacizumab in breast cancer
- County poverty levels influence genome-wide DNA methylation profiles in African American and European American women
- Association of DNA-Methylation Profiles With Immune Responses Elicited in Breast Cancer Patients Immunized With a Carbohydrate-Mimicking Peptide: A Pilot Study
- Abstract 4180: Association between genetic polymorphisms of DNMT genes and breast cancer in a nested case-control study of African Americans
- Abstract 815: Genome-wide DNA methylation signatures to predict pathologic complete response from combined neoadjuvant chemotherapy with bevacizumab in breast cancer
Showing 5 of 18 shared publications
Shelbie Stahr
University of Arkansas for Medical Sciences
16 shared publications
In database
- Association between pesticide exposure and colorectal cancer risk and incidence: A systematic review
- Cigarette smoking and prostate cancer aggressiveness among African and European American men
- Increased Utilization of Low-Dose CT for Lung Cancer Screening at an Arkansas Community Oncology Clinic
- Carcinogenic air pollutants and breast cancer risk in the Arkansas rural community health study: A nested case-control study
- Abstract PO-201: Smoking as a risk factor for the aggressive prostate cancer for African-American men from the North Carolina–Louisiana Prostate Cancer Project (PCaP)
Showing 5 of 16 shared publications
L. Joseph Su
Southwestern Medical Center (US)
12 shared publications
- Association between pesticide exposure and colorectal cancer risk and incidence: A systematic review
- Increased Utilization of Low-Dose CT for Lung Cancer Screening at an Arkansas Community Oncology Clinic
- Carcinogenic air pollutants and breast cancer risk in the Arkansas rural community health study: A nested case-control study
- Abstract PO-038: Colorectal cancer health disparity among African Americans: A qualitative study at the community level, exploring the connection between low access to resources, diet, and colorectal health
- Abstract P164: Risk Factors Of Undiagnosed Diabetes And Hypertension In Arkansas
Showing 5 of 12 shared publications
Susan Kadlubar
University of Arkansas for Medical Sciences
8 shared publications
In database
- Genome-wide DNA methylation signatures to predict pathologic complete response from combined neoadjuvant chemotherapy with bevacizumab in breast cancer
- County poverty levels influence genome-wide DNA methylation profiles in African American and European American women
- Association of DNA-Methylation Profiles With Immune Responses Elicited in Breast Cancer Patients Immunized With a Carbohydrate-Mimicking Peptide: A Pilot Study
- Abstract 4180: Association between genetic polymorphisms of DNMT genes and breast cancer in a nested case-control study of African Americans
- Abstract 815: Genome-wide DNA methylation signatures to predict pathologic complete response from combined neoadjuvant chemotherapy with bevacizumab in breast cancer
Showing 5 of 8 shared publications
Issam Makhoul
Southwestern Medical Center
8 shared publications
In database
- Biomarkers of inflammation, hypercoagulability and endothelial injury predict early asymptomatic doxorubicin-induced cardiotoxicity in breast cancer patients.
- Genome-Wide DNA Methylation Signatures Predict the Early Asymptomatic Doxorubicin-Induced Cardiotoxicity in Breast Cancer
- Genome-wide DNA methylation signatures to predict pathologic complete response from combined neoadjuvant chemotherapy with bevacizumab in breast cancer
- Association of DNA-Methylation Profiles With Immune Responses Elicited in Breast Cancer Patients Immunized With a Carbohydrate-Mimicking Peptide: A Pilot Study
- Abstract 815: Genome-wide DNA methylation signatures to predict pathologic complete response from combined neoadjuvant chemotherapy with bevacizumab in breast cancer
Showing 5 of 8 shared publications
Eryn K. Matich
University of Arkansas for Medical Sciences
8 shared publications
In database
- Association between pesticide exposure and colorectal cancer risk and incidence: A systematic review
- Biochemical validation of self-reported electronic nicotine delivery system and tobacco heaviness of use.
- Geospatial Assessment of Pesticide Concentration in Ambient Air and Colorectal Cancer Incidence in Arkansas, 2013–2017
- A Case-Control Study of Dietary Choline Intake and Risk of Colorectal Cancer Modified by Dietary B-Vitamin Intake
- Abstract PO-038: Colorectal cancer health disparity among African Americans: A qualitative study at the community level, exploring the connection between low access to resources, diet, and colorectal health
Showing 5 of 8 shared publications
Sarah A. Mayberry
The University of Texas Southwestern Medical Center (US)
7 shared publications
- Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study
- Additional file 1 of Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study
- Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study
- Additional file 1 of Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study
- Additional file 2 of Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study
Showing 5 of 7 shared publications
Hui-Yi Lin
Louisiana State University Health Sciences Center New Orleans (US)
7 shared publications
- Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study
- Additional file 1 of Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study
- Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study
- Additional file 1 of Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study
- Additional file 2 of Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study
Showing 5 of 7 shared publications
Gail Runnells
University of Arkansas for Medical Sciences
6 shared publications
In database
- County poverty levels influence genome-wide DNA methylation profiles in African American and European American women
- Carcinogenic air pollutants and breast cancer risk in the Arkansas rural community health study: A nested case-control study
- Abstract 4180: Association between genetic polymorphisms of DNMT genes and breast cancer in a nested case-control study of African Americans
- Abstract C062: Racial differences in genome-wide DNA methylation profiles by county poverty levels among women residing in Arkansas
- Abstract 4180: Association between genetic polymorphisms of DNMT genes and breast cancer in a nested case-control study of African Americans
Showing 5 of 6 shared publications
Valentina K. Todorova
University of Arkansas for Medical Sciences
6 shared publications
In database
- Biomarkers of inflammation, hypercoagulability and endothelial injury predict early asymptomatic doxorubicin-induced cardiotoxicity in breast cancer patients.
- Genome-wide DNA methylation signatures to predict pathologic complete response from combined neoadjuvant chemotherapy with bevacizumab in breast cancer
- Abstract 815: Genome-wide DNA methylation signatures to predict pathologic complete response from combined neoadjuvant chemotherapy with bevacizumab in breast cancer
- Abstract LB-174: Genome-wide DNA methylation signatures predict the early asymptomatic doxorubicin-induced cardiotoxicity in breast cancer
- Abstract 815: Genome-wide DNA methylation signatures to predict pathologic complete response from combined neoadjuvant chemotherapy with bevacizumab in breast cancer
Showing 5 of 6 shared publications
L. Joseph Su
The University of Texas Southwestern Medical Center (US)
6 shared publications
- Biomarkers of inflammation, hypercoagulability and endothelial injury predict early asymptomatic doxorubicin-induced cardiotoxicity in breast cancer patients.
- Genome-wide DNA methylation signatures to predict pathologic complete response from combined neoadjuvant chemotherapy with bevacizumab in breast cancer
- Abstract C062: Racial differences in genome-wide DNA methylation profiles by county poverty levels among women residing in Arkansas
- Abstract LB-174: Genome-wide DNA methylation signatures predict the early asymptomatic doxorubicin-induced cardiotoxicity in breast cancer
- Abstract PO-201: Smoking as a risk factor for the aggressive prostate cancer for African-American men from the North Carolina–Louisiana Prostate Cancer Project (PCaP)
Showing 5 of 6 shared publications
Se‐Ran Jun
University of Arkansas for Medical Sciences
6 shared publications
In database
- A narrative review of metabolomics approaches in identifying biomarkers of doxorubicin-induced cardiotoxicity
- Abstract 3680: Distinctive metabolomics profiles associated with African American current smokers who have high aggressive prostate cancer
- Systematic review of metabolomics approaches in identifying biomarkers of chemotherapy-induced cardiotoxicity among breast cancer patients
- Abstract 3625: Metabolic phenotypes of doxorubicin-induced cardiotoxicity in breast cancer patients
- Abstract C089: Modulation of DNA methylation by plasma folate and heavy metals in relation to prostate cancer aggressiveness
Showing 5 of 6 shared publications
L. Joseph Su
The University of Texas Southwestern Medical Center (US)
6 shared publications
- Additional file 1 of Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study
- Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study
- Additional file 1 of Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study
- Additional file 2 of Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study
- Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study
Showing 5 of 6 shared publications
Tung-Chin Chiang
University of Arkansas for Medical Sciences
5 shared publications
In database
- Geospatial Assessment of Pesticide Concentration in Ambient Air and Colorectal Cancer Incidence in Arkansas, 2013–2017
- Abstract 4180: Association between genetic polymorphisms of DNMT genes and breast cancer in a nested case-control study of African Americans
- Abstract 4180: Association between genetic polymorphisms of DNMT genes and breast cancer in a nested case-control study of African Americans
- Abstract 1450: Interactions of DNMTs genetic variants associated with breast cancer risk
- Abstract B015: Racial differences in epigenetic aging and its impact on expression of T-cell inhibitory receptors
Michael Bauer
University of Arkansas for Medical Sciences
5 shared publications
In database
- Genome-Wide DNA Methylation Signatures Predict the Early Asymptomatic Doxorubicin-Induced Cardiotoxicity in Breast Cancer
- Increased Utilization of Low-Dose CT for Lung Cancer Screening at an Arkansas Community Oncology Clinic
- Abstract LB-174: Genome-wide DNA methylation signatures predict the early asymptomatic doxorubicin-induced cardiotoxicity in breast cancer
- Abstract B015: Racial differences in epigenetic aging and its impact on expression of T-cell inhibitory receptors
- Association of DNA methylation signatures with cognitive performance among smokers and ex-smokers
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