P
Ping-Ching Hsu
Federal Grant PI
Associate Professor
faculty
Environmental Health Sciences, College of Public Health
14 h-index
93 pubs
731 cited
Research Areas
Biography and Research Information
OverviewAI-generated summary
Ping-Ching Hsu investigates the intersection of environmental exposures and human health, with a particular focus on cancer incidence and etiology. Her work includes systematic reviews and geospatial analyses to understand the association between pesticide exposure and colorectal cancer risk. Dr. Hsu also explores the application of metabolomics in identifying biomarkers for various health conditions, including doxorubicin-induced cardiotoxicity in breast cancer patients and maternal health outcomes following pregnancies affected by congenital heart defects.
Her research group is funded by the National Institute of Environmental Health Sciences through two principal investigator grants totaling over $778,000. These grants support studies on rural community health and environmental research, as well as efforts to promote scientific and workforce diversity within these communities. Dr. Hsu collaborates extensively with colleagues at the University of Arkansas for Medical Sciences, including Renny S. Lan, Shelbie Stahr, Eryn K. Matich, and Lora J. Rogers, with whom she has co-authored numerous publications.
Metrics
- h-index: 14
- Publications: 93
- Citations: 731
Selected Publications
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Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study (2026)
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Modified tumor uptake and biodistribution of nanoparticles coated with small extracellular vesicle membranes derived from distinct tumor cell lines (2026)
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DNA Methylation in Lung Cancer: Predictive Biomarkers for Effective Immunotherapy (2025)
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Abstract A058: Plasma folate and folic acid status in relation to prostate cancer aggressiveness: Insights into racial disparities from the PCaP study (2025)
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Abstract A064: Racial disparities in folate metabolism, genetic variants, and prostate cancer aggressiveness (2025)
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Abstract C089: Modulation of DNA methylation by plasma folate and heavy metals in relation to prostate cancer aggressiveness (2025)
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Carcinogenic air pollutants and breast cancer risk in the Arkansas rural community health study: A nested case-control study (2025)
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A Case-Control Study of Dietary Choline Intake and Risk of Colorectal Cancer Modified by Dietary B-Vitamin Intake (2024)
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Organic Food Consumption and the Risk of Type 2 Diabetes in the Sister Study (2024)
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Cigarette smoking and prostate cancer aggressiveness among African and European American men (2024)
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Abstract 7005: Distinct DNA methylation patterns between early-onset and average-onset colorectal cancer patients (2024)
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Abstract 3625: Metabolic phenotypes of doxorubicin-induced cardiotoxicity in breast cancer patients (2024)
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Stem Cell Theory of Cancer: Clinical Implications for Cellular Metabolism and Anti-Cancer Metabolomics (2024)
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Saliva and Urine Sampling to Quantify Trace Metal Exposure for Epidemiologic Studies (2023)
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Current Practices in LC-MS Untargeted Metabolomics: A Scoping Review on the Use of Pooled Quality Control Samples (2023)
Federal Grants 2 $778,801 total
NIH/National Institute of Environmental Health Sciences
Contact PI
Dec 2024 - Nov 2029
Arkansas Rural Community Health-Healthy Environmental Research (ARCH-HER) Study
NIH/National Institute of Environmental Health Sciences
Contact PI
Dec 2024 - Nov 2029
Research Interests
My laboratory is interested in biomarker discovery using global metabolite profiling (metabolomics). We use metabolomics to identify the “metabotype” that are consisting of oxidized lipids and metabolites in patients and animal models hoping to find early indicators of chemotherapy-induced cardiotoxicity and cognitive impairments in breast cancer patients. We also work on addressing the issue of cigarette smoking especially menthol cigarette smoking that’s contributing to the disparity of lethal prostate cancer in African-Americans, by identifying smoking-related metabolomics patterns associated with highly aggressive prostate cancer in African-Americans compared to European-Americans.
Grants & Funding
- Feasibility study to improve the assessment of cancer treatment-related cognitive impairment. Winthrop P. Rockefeller Team Science Pilot Award Principal Investigator
- Long-term effects of electronic cigarettes on brain health NIH/Nat. Inst. on Drug Abuse - Pass Through: Wake Forest University Principal Investigator
- Promoting scientific and workforce diversity by enriching the Arkansas Rural Community Health Study (ARCH) among Mother-Daughter Pairs NIH/Nat. Inst. of Environmental Health Sciences Principal Investigator
- Long-term effects of electronic cigarettes on brain health NIH/Nat. Inst. on Drug Abuse - Pass Through: Wake Forest University Principal Investigator
- Long-term effects of electronic cigarettes on brain health NIH/Nat. Inst. on Drug Abuse - Pass Through: Wake Forest University Principal Investigator
- Long-term effects of electronic cigarettes on brain health NIH/Nat. Inst. on Drug Abuse - Pass Through: Wake Forest University Principal Investigator
- Metabolomics of Menthol Cigarette Smoking and Risk for Aggressive Prostate Cancer Among African American Men US Department of Defense Principal Investigator
- Promoting scientific and workforce diversity by enriching the Arkansas Rural Community Health Study (ARCH) among Mother-Daughter Pairs NIH/Nat. Inst. of Environmental Health Sciences Principal Investigator
Collaboration Network
Top Collaborators
Renny S. Lan
University of Arkansas for Medical Sciences
16 shared publications
In database
- Current Practices in LC-MS Untargeted Metabolomics: A Scoping Review on the Use of Pooled Quality Control Samples
- A narrative review of metabolomics approaches in identifying biomarkers of doxorubicin-induced cardiotoxicity
- Data from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental figure 1 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental table 5 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
Showing 5 of 16 shared publications
Peter G. Shields
The Ohio State University (US)
15 shared publications
- Untargeted Metabolomics and Body Mass in Adolescents: A Cross-Sectional and Longitudinal Analysis
- Data from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental figure 1 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental table 5 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental table 2 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
Showing 5 of 15 shared publications
Theodore M. Brasky
14 shared publications
- Data from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental figure 1 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental table 5 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental table 2 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental table 3 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
Showing 5 of 14 shared publications
Cătălin Marian
14 shared publications
- Data from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental figure 1 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental table 5 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental table 2 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental table 3 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
Showing 5 of 14 shared publications
Amrita K. Cheema
14 shared publications
- Data from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental figure 1 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental table 5 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental table 2 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental table 3 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
Showing 5 of 14 shared publications
Habtom W. Ressom
14 shared publications
- Data from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental figure 1 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental table 5 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental table 2 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental table 3 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
Showing 5 of 14 shared publications
Christopher A. Loffredo
14 shared publications
- Data from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental figure 1 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental table 5 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental table 2 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental table 3 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
Showing 5 of 14 shared publications
Wallace B. Pickworth
14 shared publications
- Data from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental figure 1 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental table 5 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental table 2 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
- Supplemental table 3 from Menthol Smokers: Metabolomic Profiling and Smoking Behavior
Showing 5 of 14 shared publications
Shelbie Stahr
University of Arkansas for Medical Sciences
11 shared publications
In database
- Association between pesticide exposure and colorectal cancer risk and incidence: A systematic review
- Cigarette smoking and prostate cancer aggressiveness among African and European American men
- Increased Utilization of Low-Dose CT for Lung Cancer Screening at an Arkansas Community Oncology Clinic
- Carcinogenic air pollutants and breast cancer risk in the Arkansas rural community health study: A nested case-control study
- Abstract 1450: Interactions of <i>DNMTs</i> genetic variants associated with breast cancer risk
Showing 5 of 11 shared publications
L. Joseph Su
Southwestern Medical Center (US)
9 shared publications
- Association between pesticide exposure and colorectal cancer risk and incidence: A systematic review
- Increased Utilization of Low-Dose CT for Lung Cancer Screening at an Arkansas Community Oncology Clinic
- Carcinogenic air pollutants and breast cancer risk in the Arkansas rural community health study: A nested case-control study
- Abstract P164: Risk Factors Of Undiagnosed Diabetes And Hypertension In Arkansas
- Abstract 3680: Distinctive metabolomics profiles associated with African American current smokers who have high aggressive prostate cancer
Showing 5 of 9 shared publications
Eryn K. Matich
University of Arkansas for Medical Sciences
7 shared publications
In database
- Association between pesticide exposure and colorectal cancer risk and incidence: A systematic review
- Biochemical validation of self-reported electronic nicotine delivery system and tobacco heaviness of use.
- Geospatial Assessment of Pesticide Concentration in Ambient Air and Colorectal Cancer Incidence in Arkansas, 2013–2017
- A Case-Control Study of Dietary Choline Intake and Risk of Colorectal Cancer Modified by Dietary B-Vitamin Intake
- Abstract P164: Risk Factors Of Undiagnosed Diabetes And Hypertension In Arkansas
Showing 5 of 7 shared publications
Edgar T. Ellis
Columbia University (US)
5 shared publications
- Cigarette smoking and prostate cancer aggressiveness among African and European American men
- Increased Utilization of Low-Dose CT for Lung Cancer Screening at an Arkansas Community Oncology Clinic
- Carcinogenic air pollutants and breast cancer risk in the Arkansas rural community health study: A nested case-control study
- Abstract B096: Cigarette smoking and prostate cancer aggressiveness among African and European American men
- Saliva and Urine Sampling to Quantify Trace Metal Exposure for Epidemiologic Studies
Michael Bauer
University of Arkansas for Medical Sciences
4 shared publications
In database
- Genome-Wide DNA Methylation Signatures Predict the Early Asymptomatic Doxorubicin-Induced Cardiotoxicity in Breast Cancer
- Increased Utilization of Low-Dose CT for Lung Cancer Screening at an Arkansas Community Oncology Clinic
- Abstract B015: Racial differences in epigenetic aging and its impact on expression of T-cell inhibitory receptors
- Association of DNA methylation signatures with cognitive performance among smokers and ex-smokers
Se‐Ran Jun
University of Arkansas for Medical Sciences
4 shared publications
In database
- A narrative review of metabolomics approaches in identifying biomarkers of doxorubicin-induced cardiotoxicity
- Abstract 3680: Distinctive metabolomics profiles associated with African American current smokers who have high aggressive prostate cancer
- Systematic review of metabolomics approaches in identifying biomarkers of chemotherapy-induced cardiotoxicity among breast cancer patients
- Abstract 3625: Metabolic phenotypes of doxorubicin-induced cardiotoxicity in breast cancer patients
Lora J. Rogers
University of Arkansas for Medical Sciences
4 shared publications
In database
- Abstract 1450: Interactions of <i>DNMTs</i> genetic variants associated with breast cancer risk
- Abstract B015: Racial differences in epigenetic aging and its impact on expression of T-cell inhibitory receptors
- Saliva and Urine Sampling to Quantify Trace Metal Exposure for Epidemiologic Studies
- Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study
Similar Researchers
Based on overlapping research topics
Eryn K. Matich
University of Arkansas for Medical Sciences
Pesticide and Herbicide Environmental Studies
Metabolomics and Mass Spectrometry Studies
Environmental Health Research
Shelbie Stahr
University of Arkansas for Medical Sciences
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Tamier L. Wells
University of Arkansas for Medical Sciences
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Mohammed F. Faramawi
University of Arkansas for Medical Sciences
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Cancer-related molecular mechanisms research
Meta-analysis and systematic reviews
Oluwakemi Olayinka
University of Arkansas for Medical Sciences
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Meta-analysis and systematic reviews
Kaitlyn H. Taylor
University of Arkansas for Medical Sciences
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