Ping-Ching Hsu
Associate Professor
Also affiliated: National Defense University (2003–2004); Tri-Service General Hospital (2003–2005); Chang Gung University (2002); Georgetown University (2010); Taipei Medical University Hospital (2002); The Ohio State University Wexner Medical Center (2013); Southwestern Medical Center (2022); Ohio University (2015); Winthrop Rockefeller Foundation (2020–2026); Arkansas Department of Health (2020–2025); Southwestern Medical Center (2022); Taipei Medical University (2001–2002); The Ohio State University (2012–2016); National Defense Medical Center (2003–2005); The University of Texas Southwestern Medical Center (2022)
Faculty Researcher
Environmental Health Sciences, College of Public Health
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Ping-Ching Hsu's research focuses on the intersection of environmental exposures, health outcomes, and the application of advanced analytical techniques. She has investigated the association between pesticide exposure and the risk and incidence of colorectal cancer, examining geospatial data from Arkansas. Her work also explores the impact of environmental factors and lifestyle choices on various cancers, including a study on cigarette smoking and prostate cancer aggressiveness among different racial groups.
Hsu's research extends to identifying biomarkers for health conditions using metabolomics. She has contributed to understanding cardiotoxicity induced by doxorubicin in breast cancer patients and has reviewed metabolomics approaches for identifying these cardiotoxicity biomarkers. Additionally, her work includes exploring metabolomics signatures related to maternal health after pregnancies affected by congenital heart defects and validating self-reported data on electronic nicotine delivery systems and tobacco use.
As a Principal Investigator, Hsu has secured funding from the NIH/National Institute of Environmental Health Sciences for studies focused on rural community health and environmental research, including initiatives promoting diversity among mother-daughter pairs. Her scholarship metrics include an h-index of 14, with 94 total publications and 755 citations. She leads a research group and collaborates extensively with colleagues at the University of Arkansas for Medical Sciences.
Metrics
- h-index: 14
- Publications: 96
- Citations: 774
Selected Publications
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Sézary Syndrome Biomarker, T Cell Transcription Factors and Cytokine Genes Provide Novel Insight into Response During Mogamulizumab Treatment (2026)
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Metabolic phenotypes of doxorubicin-induced cardiotoxicity among patients with breast cancer (2026)
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Abstract LB219: Proteomic signatures of doxorubicin-induced lymphatic dysfunction in tumor-bearing rats (2026)
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Abstract 7649: Urinary arsenic speciation and metabolic indices associate with exposure chemistry and prostate cancer aggressiveness. (2026)
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Additional file 2 of Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study (2026)
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Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study (2026)
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Additional file 2 of Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study (2026)
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Additional file 1 of Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study (2026)
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Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study (2026)
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Additional file 1 of Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study (2026)
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Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study (2026)
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Modified tumor uptake and biodistribution of nanoparticles coated with small extracellular vesicle membranes derived from distinct tumor cell lines (2026)
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DNA Methylation in Lung Cancer: Predictive Biomarkers for Effective Immunotherapy (2025)
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Abstract A058: Plasma folate and folic acid status in relation to prostate cancer aggressiveness: Insights into racial disparities from the PCaP study (2025)
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Abstract A064: Racial disparities in folate metabolism, genetic variants, and prostate cancer aggressiveness (2025)
Federal Grants 2 $778,801 total
Arkansas Rural Community Health-Healthy Environmental Research (ARCH-HER) Study
Research Interests
My laboratory is interested in biomarker discovery using global metabolite profiling (metabolomics). We use metabolomics to identify the “metabotype” that are consisting of oxidized lipids and metabolites in patients and animal models hoping to find early indicators of chemotherapy-induced cardiotoxicity and cognitive impairments in breast cancer patients. We also work on addressing the issue of cigarette smoking especially menthol cigarette smoking that’s contributing to the disparity of lethal prostate cancer in African-Americans, by identifying smoking-related metabolomics patterns associated with highly aggressive prostate cancer in African-Americans compared to European-Americans.
Grants & Funding
As listed on this researcher's institutional profile. Federal awards with verified records are shown above.
- Feasibility study to improve the assessment of cancer treatment-related cognitive impairment. Winthrop P. Rockefeller Team Science Pilot Award Principal Investigator
- Long-term effects of electronic cigarettes on brain health NIH/Nat. Inst. on Drug Abuse via Wake Forest University Principal Investigator
- Metabolomics of Menthol Cigarette Smoking and Risk for Aggressive Prostate Cancer Among African American Men US Department of Defense Principal Investigator
- Modulation effect of folate on the association between inorganic arsenic and aggressive prostate cancer US Department of Defense via University of Texas Southwestern Medical Center Principal Investigator
- Center for Studies of Host Response to Cancer Therapy NIH Principal Investigator
- Component A: Arkansas Proposal to participate in the Birth Defect Study to Evaluate Pregnancy exposureS (BD-STEPS II) Center for Disease Control and Prevention Co-Investigator
- Evaluating Impact of Diet and Fresh Food Access on Aggressive Prostate Cancer using Multi-Level Modeling NIH/Nat. Cancer Institute Principal Investigator
- Interaction of lug microbiome and tobaccorelated insults in lung cancer UAMS Internal Research Awards Principal Investigator
- Cancer Prevention and Population Sciences Program UAMS College of Medicine Principal Investigator
- RFA-DD-18-001 Birth Defects Study To Evaluate Pregnancy exposures (BD-STEPS) II Core & Component B Steps -Stillbirth NIH Co-Investigator
- Metabolomics of menthol cigarette smoking and risk for aggressive prostate cancer among African-American men US Department of Defense Principal Investigator
Collaboration Network
Top Collaborators
- Association between pesticide exposure and colorectal cancer risk and incidence: A systematic review
- Increased Utilization of Low-Dose CT for Lung Cancer Screening at an Arkansas Community Oncology Clinic
- Carcinogenic air pollutants and breast cancer risk in the Arkansas rural community health study: A nested case-control study
- Abstract P164: Risk Factors Of Undiagnosed Diabetes And Hypertension In Arkansas
- Abstract 3680: Distinctive metabolomics profiles associated with African American current smokers who have high aggressive prostate cancer
Showing 5 of 10 shared publications
- Association between pesticide exposure and colorectal cancer risk and incidence: A systematic review
- Cigarette smoking and prostate cancer aggressiveness among African and European American men
- Increased Utilization of Low-Dose CT for Lung Cancer Screening at an Arkansas Community Oncology Clinic
- Carcinogenic air pollutants and breast cancer risk in the Arkansas rural community health study: A nested case-control study
- Abstract 1450: Interactions of <i>DNMTs</i> genetic variants associated with breast cancer risk
Showing 5 of 9 shared publications
- Association between pesticide exposure and colorectal cancer risk and incidence: A systematic review
- Geospatial Assessment of Pesticide Concentration in Ambient Air and Colorectal Cancer Incidence in Arkansas, 2013–2017
- A Case-Control Study of Dietary Choline Intake and Risk of Colorectal Cancer Modified by Dietary B-Vitamin Intake
- Abstract P164: Risk Factors Of Undiagnosed Diabetes And Hypertension In Arkansas
- Abstract PO-160: Associations between diet and food security with colorectal cancer-based health disparity among African Americans
Showing 5 of 6 shared publications
- Cigarette smoking and prostate cancer aggressiveness among African and European American men
- Increased Utilization of Low-Dose CT for Lung Cancer Screening at an Arkansas Community Oncology Clinic
- Carcinogenic air pollutants and breast cancer risk in the Arkansas rural community health study: A nested case-control study
- Abstract B096: Cigarette smoking and prostate cancer aggressiveness among African and European American men
- Saliva and Urine Sampling to Quantify Trace Metal Exposure for Epidemiologic Studies
- Genome-Wide DNA Methylation Signatures Predict the Early Asymptomatic Doxorubicin-Induced Cardiotoxicity in Breast Cancer
- Increased Utilization of Low-Dose CT for Lung Cancer Screening at an Arkansas Community Oncology Clinic
- Abstract B015: Racial differences in epigenetic aging and its impact on expression of T-cell inhibitory receptors
- Association of DNA methylation signatures with cognitive performance among smokers and ex-smokers
- Abstract 3680: Distinctive metabolomics profiles associated with African American current smokers who have high aggressive prostate cancer
- Systematic review of metabolomics approaches in identifying biomarkers of chemotherapy-induced cardiotoxicity among breast cancer patients
- Abstract 3625: Metabolic phenotypes of doxorubicin-induced cardiotoxicity in breast cancer patients
- Abstract C089: Modulation of DNA methylation by plasma folate and heavy metals in relation to prostate cancer aggressiveness
- Abstract 1450: Interactions of <i>DNMTs</i> genetic variants associated with breast cancer risk
- Abstract B015: Racial differences in epigenetic aging and its impact on expression of T-cell inhibitory receptors
- Saliva and Urine Sampling to Quantify Trace Metal Exposure for Epidemiologic Studies
- Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study
- Association between pesticide exposure and colorectal cancer risk and incidence: A systematic review
- A Case-Control Study of Dietary Choline Intake and Risk of Colorectal Cancer Modified by Dietary B-Vitamin Intake
- Abstract PO-160: Associations between diet and food security with colorectal cancer-based health disparity among African Americans
- Genome-Wide DNA Methylation Signatures Predict the Early Asymptomatic Doxorubicin-Induced Cardiotoxicity in Breast Cancer
- Abstract PO-160: Associations between diet and food security with colorectal cancer-based health disparity among African Americans
- Abstract A058: Plasma folate and folic acid status in relation to prostate cancer aggressiveness: Insights into racial disparities from the PCaP study
- Geospatial Assessment of Pesticide Concentration in Ambient Air and Colorectal Cancer Incidence in Arkansas, 2013–2017
- Abstract 1450: Interactions of <i>DNMTs</i> genetic variants associated with breast cancer risk
- Abstract B015: Racial differences in epigenetic aging and its impact on expression of T-cell inhibitory receptors
- Genome-Wide DNA Methylation Signatures Predict the Early Asymptomatic Doxorubicin-Induced Cardiotoxicity in Breast Cancer
- Systematic review of metabolomics approaches in identifying biomarkers of chemotherapy-induced cardiotoxicity among breast cancer patients
- Geospatial Assessment of Pesticide Concentration in Ambient Air and Colorectal Cancer Incidence in Arkansas, 2013–2017
- A Case-Control Study of Dietary Choline Intake and Risk of Colorectal Cancer Modified by Dietary B-Vitamin Intake
- Geospatial Assessment of Pesticide Concentration in Ambient Air and Colorectal Cancer Incidence in Arkansas, 2013–2017
- Carcinogenic air pollutants and breast cancer risk in the Arkansas rural community health study: A nested case-control study
- Carcinogenic air pollutants and breast cancer risk in the Arkansas rural community health study: A nested case-control study
- Abstract 1450: Interactions of <i>DNMTs</i> genetic variants associated with breast cancer risk
- Cognition, Aryl Hydrocarbon Receptor Repressor Methylation, and Abstinence Duration-Associated Multimodal Brain Networks in Smoking and Long-Term Smoking Cessation
- Association of DNA methylation signatures with cognitive performance among smokers and ex-smokers
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